Metastatic testicular teratoma of the nasal cavity: a rare cause of severe intractable epistaxis

1998 ◽  
Vol 112 (11) ◽  
pp. 1078-1081 ◽  
Author(s):  
M. Tariq ◽  
P. Gluckman ◽  
P. Thebe
Keyword(s):  
Germ Cell ◽  
Nasal Cavity ◽  
Paranasal Sinuses ◽  
Rare Case ◽  
Germ Cell Tumour ◽  
Reproductive Organs ◽  
Malignant Neoplasms ◽  
Germ Cell Tumours ◽  
Lymphatic Route ◽  
Intractable Epistaxis

AbstractMalignant neoplasms of the nasal cavity and paranasal sinuses are uncommon. Choriocarcinoma is a highly malignant germ cell tumour occurring in the reproductive organs. Metastasis may be principally by the lymphatic route as in other germ cell tumours but choriocarcinoma is also known to spread haematogenously. We present a rare case of metastatic choriocarcinoma to the nasal cavity from testicular teratoma presenting with intractable epistaxis in a 32-year-old Caucasian male, who ultimately succumbed to this disease.

scholarly journals Malignant mixed germ cell tumours- A rare case report with unusual presentation in a 05 years old female child

2021 ◽  
Vol 8 (3) ◽  
pp. 425-428
Author(s):  
Harendra Kumar ◽  
Ritu Sonkar ◽  
Pooja Nagayach ◽  
Puneet Srivastava
Keyword(s):  
Germ Cell ◽  
Rare Case ◽  
Case Reports ◽  
Germ Cell Tumour ◽  
Female Child ◽  
Malignant Neoplasms ◽  
Germ Cell Tumours ◽  
Rare Case Report ◽  
Cell Components ◽  
Yolk Sac Tumour

Mixed germ cell tumours (MGCT) of the ovary are malignant neoplasms of the ovary comprising of two or more types of germ cell components. Most of the malignant MGCT consists of dysgerminoma accompanied by endodermal sinus tumours, immature teratoma or choriocarcinoma. There are only few case reports of MGCTs with different combinations of malignant components. We present a very rare case of malignant MGCT in a 05 years old female child, who presented with difficulty in defecation for 6 months, swelling over sacral region for 2 months, along with bilateral inguinal swellings and difficulty in urination for 1 week. Swelling was firm, non-mobile & non-tender measuring 6.6x5 cm. On cytology it was diagnosed as malignant germ cell tumour, which was confirmed on histology as malignant MGCT (predominantly yolk sac tumour >90% and embryonal carcinoma (<10%)), metastasizing into bilateral inguinal lymph nodes.

Teratocarcinosarcoma of the nose, paranasal sinuses and nasopharynx

2003 ◽  
Vol 117 (4) ◽  
pp. 321-324 ◽  
Author(s):  
Kishore Chandra Prasad ◽  
Radha R. Pai ◽  
K. Padmanabhan ◽  
Sanjeev Chawla
Keyword(s):  
Germ Cell ◽  
Head And Neck ◽  
Paranasal Sinuses ◽  
Rare Case ◽  
Treatment Options ◽  
Germ Cell Tumour ◽  
Malignant Tumours ◽  
Rare Tumours ◽  
Upper Jaw ◽  
Tumour Origin

Teratomas affecting the head and neck are rare tumours of ambiguous origin. The benign form is seen in children and mostly affects the nasopharynx. Malignant tumours in the upper jaw have been reported rarely. They are almost exclusively seen in the adult male. They are highly aggressive tumours that are difficult to diagnose pre-operatively due to the varied histological patterns. Treatment options available are surgery, radiotherapy or a combination of both. Despite intensive treatment, the prognosis is still poor. A rare case of teratocarcinosarcoma of the nose, paranasal sinuses and nasopharynx in a 25-year-old male is presented. The tumour had a non-germ cell tumour origin. The clinical features, pathologic characteristics and treatment are detailed. It was managed by surgery, radiotherapy and chemotherapy.

scholarly journals Clinical presentation and management of malignant germ cell ovarian tumours in BPKMCH

2016 ◽  
Author(s):  
Jitendra Pariyar ◽  
Binuma Shrestha
Keyword(s):  
Neoadjuvant Chemotherapy ◽  
Germ Cell ◽  
Clinical Presentation ◽  
Early Stage ◽  
Germ Cell Tumour ◽  
Cystic Teratoma ◽  
Germ Cell Tumours ◽  
Early Stage Disease ◽  
Cancer Hospital ◽  
Disseminated Disease

Background: Germ cell malignancies account for about 5% of all ovarian cancers. These tumours grow rapidly and often produce symptoms quicker than the slow growing epithelial tumour. Commonly seen in the first two decades of life germ cell malignancies are highly chemosensitive and are potentially curable with surgery and chemotherapy. This study is the first of its kind regarding the epidemiology, management and outcome of patients with malignant germ cell tumour in Nepal. Objective: To analyze the clinical presentation and management outcomes of malignant germ cell tumours managed in B.P. Koirala Memorial Cancer Hospital, Nepal. Methodology: Descriptive study conducted in B.P. Koirala Memorial Cancer Hospital, Nepal. Case records of malignant germ cell tumours attending the hospital from January 1999 to December 2009 were analyzed regarding their illness history, clinical examination, investigations, treatment, follow-up and outcomes measured. Observations: Total 65 cases of malignant germ cell tumours with age range from 2 to 58 years (mean 21.7 years) were received. 42% cases were Tibeto-Burmese; 30% were Indo-Aryans. There were 15 cases (23%) of dysgeminoma, 21 endodermal sinus tumor (32%), 16 Immature Cystic Teratoma (24.5%), 9 (14%) Mixed Germ Cell, 2 unclassified GCT (3.5%) and 2 malignant transformation in teratoma (3.5%). 33 (49.5%) patients had early stage disease, 37 (57%) underwent fertility preserving surgery. 4 cases (9%) due to disseminated disease, underwent neoadjuvant chemotherapy followed by debulking surgery. 51 cases (78.5%) received adjuvant chemotherapy (BEP or EP regimen). The overall survival was 70%. Conclusion: Early stage germ cell malignancies can be safely managed by fertility preserving surgery followed by, chemotherapy if indicated. For advanced diseases, neoadjuvant chemotherapy followed by surgery can be undertaken with curable intent.

Malignant neoplasms of the nasal cavity and paranasal sinuses: A series of 256 patients in Mexico City and Monterrey. Is air pollution the missing link?☆☆☆

2000 ◽  
Vol 122 (4) ◽  
pp. 499-508 ◽  
Author(s):  
LILIAN CALDERÓN-GARCIDUEÑAS ◽  
RICARDO DELGADO ◽  
ANA CALDERÓN-GARCIDUEÑAS ◽  
ABELARDO MENESES ◽  
LUZ MARIA RUIZ ◽  
...  
Keyword(s):  
Air Pollution ◽  
Nasal Cavity ◽  
Mexico City ◽  
Paranasal Sinuses ◽  
Malignant Neoplasms ◽  
Missing Link

Pineal tumours

2019 ◽  
pp. 427-438
Author(s):  
Mueez Waqar ◽  
Samantha Mills ◽  
Conor L Mallucci ◽  
Michael D Jenkinson
Keyword(s):  
Germ Cell ◽  
Adjuvant Radiotherapy ◽  
Residual Disease ◽  
Germ Cell Tumour ◽  
Third Ventriculostomy ◽  
Germ Cell Tumours ◽  
Line Treatment ◽  
Surgical Biopsy ◽  
First Line Treatment

Tumours of the pineal are very rare, tend to be more common in children and while there are a wide variety of pathologies the majority are germ cell tumours and pineal parenchymal tumours. These tumours usually present with hydrocephalus and endoscopic third ventriculostomy is the operation of choice. It is important to test for tumour markers in the blood and cerebrospinal fluid, since the diagnosis of a secreting germ cell tumour precludes the need for surgery. Surgical biopsy can be performed by endoscopy or with frame-based stereotaxy. For germ cell tumours chemotherapy and radiotherapy are the mainstay of treatment, but surgery has a role in the management of residual disease. For primary parenchymal tumours, maximum surgical resection is the first-line treatment and can be curative for pineocytoma. Pineoblastoma require adjuvant radiotherapy and for intermediate grade pineal tumours the role of radiotherapy is still being evaluated.

Small cell neuroendocrine carcinoma of the nasal cavity and paranasal sinuses: a rare case

2012 ◽  
Vol 126 (12) ◽  
pp. 1284-1286 ◽  
Author(s):  
I P Tang ◽  
S Singh ◽  
G Krishnan ◽  
L M Looi
Keyword(s):  
Nasal Cavity ◽  
Neuroendocrine Carcinoma ◽  
Paranasal Sinuses ◽  
Rare Case ◽  
Surgical Excision ◽  
Small Cell ◽  
High Rate ◽  
Intracranial Extension ◽  
Small Cell Neuroendocrine Carcinoma ◽  
Rare Tumour

AbstractObjective:We report a rare case of small cell neuroendocrine carcinoma of the nasal cavity and paranasal sinuses with intracranial extension, and discuss the management of this rare tumour.Results:Small cell neuroendocrine carcinoma involving the nasal cavity and paranasal sinuses with intracranial extension may be treated successfully with surgery alone, without development of local recurrence.Conclusion:Small cell neuroendocrine carcinoma is a locally aggressive tumour with a high rate of recurrence. Early and aggressive surgical excision with or without radiotherapy or chemotherapy can improve a patient's outcome and prognosis. Regular follow up is needed to detect any local or distant recurrence.

scholarly journals An extremely rare case of testicular malign neoplasm; alveolar subtype of rhabdomyosarcoma with long term follow-up.

2014 ◽  
Vol 4 (2) ◽  
pp. 134-135
Author(s):  
Tumay Ipekci ◽  
Yigit Akin ◽  
Burak Hoscan ◽  
Ahmet Tunckiran
Keyword(s):  
Germ Cell ◽  
Rare Case ◽  
Clinical Findings ◽  
Testicular Neoplasm ◽  
Solid Organ ◽  
Germ Cell Tumours ◽  
Long Term Follow Up ◽  
Solid Organ Tumours

Testicular neoplasm usually occur in men aged between 15 and 35. These are solid organ tumours and also should be operated when there is a suspicious clinical findings. Testis tumours are levelled after histopathology evaluation. The medical, surgical and follow-up strategies of well know testis tumours, such as seminomas, non-seminom germ cell tumours, have been established. In case of testis tumours rare entities may occur as rhabdomyosarcoma.We here presented a rare case of   alveolar subtype of rhabdomyosarcoma in testis with long term follow-up.

scholarly journals A study of ovarian tumors at Kathmandu medical college teaching hospital

2017 ◽  
Vol 7 (2) ◽  
pp. 1188-1191 ◽  
Author(s):  
Sailesh Bahadur Pradhan ◽  
Sanat Chalise ◽  
Binita Pradhan ◽  
Sailuja Maharjan
Keyword(s):  
Germ Cell ◽  
Hospital Admissions ◽  
Germ Cell Tumour ◽  
Malignant Neoplasm ◽  
Cystic Teratoma ◽  
College Teaching ◽  
Cell Tumour ◽  
Germ Cell Tumours ◽  
Cross Sectional ◽  
Epithelial Tumours

Background: Ovarian cysts, which present as neoplastic and non-neoplastic lesions, are the most common gynecological cause of hospital admissions. This study was conducted to know the spectrum of ovarian tumors.Materials and methods: A cross sectional study was carried out among all the ovarian specimens sent for histopathological examination.Results: Forty two cases were Surface epithelial tumours and 49 cases were germ cell tumour. Among Surface epithelial tumours, 34 (80.95%) were benign neoplasm, 2(4.76%) were borderline and 6 including one Krukenberg tumour (14.29%) were malignant neoplasm. Among all Germ cell tumours, 45 (91.84%) were Mature cystic teratoma, 1 (4.08%) was Immature cystic teratoma and 2 (4.08%) were Dysgerminoma. Conclusion: Incidence of Surface epithelial tumours and germ cell tumours were found to be almost equal with mild predominance of Germ cell tumour.

Sign in / Sign up

Export Citation Format

Share Document