Clinical characteristics and audiological significance of spontaneous otoacoustic emissions in tinnitus patients with normal hearing

2010 ◽  
Vol 125 (3) ◽  
pp. 246-250 ◽  
Author(s):  
D-K Kim ◽  
S-N Park ◽  
K-H Park ◽  
H G Choi ◽  
E-J Jeon ◽  
...  
Keyword(s):  
Otoacoustic Emissions ◽  
Early Stage ◽  
Otoacoustic Emission ◽  
Normal Hearing ◽  
Control Group ◽  
Study Group ◽  
Distortion Product Otoacoustic Emission ◽  
Spontaneous Otoacoustic Emissions ◽  
Distortion Product ◽  
The Mean

AbstractObjective:To define the clinical and audiological features of normal-hearing tinnitus patients with spontaneous otoacoustic emissions, and to evaluate the role of spontaneous otoacoustic emissions in tinnitus generation.Materials and methods:Thirty-two patients with spontaneous otoacoustic emissions were compared with 29 patients without spontaneous otoacoustic emissions, regarding clinical and audiological aspects.Results:The mean age of the study group subjects was significantly lower, and they experienced the kindling effect less frequently than the control group. The mean tinnitus handicap inventory score of the study group was considerably higher than that of the controls, although the difference was not statistically significant. The study group had significantly quieter tinnitus, and higher transient evoked and distortion product otoacoustic emission responses, compared with the control group.Conclusions:Normal-hearing tinnitus patients with spontaneous otoacoustic emissions have different clinical and audiological characteristics, compared with those without spontaneous otoacoustic emissions. Appropriate evaluation and treatment should be considered at an early stage in these patients.

Distortion product otoacoustic emissions following stapedectomy versus stapedotomy

2009 ◽  
Vol 124 (1) ◽  
pp. 16-18
Author(s):  
L Migirov ◽  
M Wolf
Keyword(s):  
Otoacoustic Emissions ◽  
Surgical Techniques ◽  
Otoacoustic Emission ◽  
Normal Hearing ◽  
Stapes Surgery ◽  
Distortion Product Otoacoustic Emissions ◽  
Control Group ◽  
Distortion Product Otoacoustic Emission ◽  
Distortion Product ◽  
Gap Closure

AbstractObjectives:To evaluate distortion product otoacoustic emissions following stapes surgery in patients with otosclerosis, and to compare in this respect two surgical techniques used in our department.Method:This retrospective study included 17 stapedectomy and 23 stapedotomy patients aged 16–68 years who had been followed up for at least 12 months. Distortion product otoacoustic emission results at 2, 3, 4 and 5 kHz (i.e. =f2, with 2f1 − f2 = 0.6f2) were obtained pre-operatively and four weeks post-operatively. The control group included 13 volunteers aged 18–50 years with normal hearing and normal otoscopic findings.Results:Distortion product otoacoustic emissions were detected pre-operatively in 34.8 per cent of stapedotomy patients and 29.4 per cent of stapedectomy patients, and post-operatively in 91.3 per cent of stapedotomy patients and 88.2 per cent of stapedectomy patients. The differences between the stapedotomy and stapedectomy groups were statistically insignificant for each tested frequency, both pre- and post-operatively. The patients' post-operative distortion product otoacoustic emission amplitudes were less than those of normal hearing individuals, even in patients with complete air–bone gap closure and a significant improvement in hearing.Conclusion:Distortion product otoacoustic emissions were detected in most of our patients following successful stapes surgery, and appeared to be unaffected by the surgical technique or prosthesis used.

Effect of chronic suppurative otitis media on distortion product otoacoustic emission input–output functions in conventional and ultra-high frequencies

2019 ◽  
Vol 133 (11) ◽  
pp. 995-1004
Author(s):  
S I Kirubaharane ◽  
S Palani ◽  
A Alexander ◽  
A Sreenivasan
Keyword(s):  
Otitis Media ◽  
Otoacoustic Emissions ◽  
Otoacoustic Emission ◽  
Chronic Suppurative Otitis Media ◽  
Distortion Product Otoacoustic Emissions ◽  
Control Group ◽  
Clinical Group ◽  
Distortion Product Otoacoustic Emission ◽  
Suppurative Otitis Media ◽  
Distortion Product

AbstractBackgroundDetection and valid measurements of distortion product otoacoustic emissions are not influenced by cochlear status alone, but also by middle-ear status. There is a need to understand the use of ultra-high frequency distortion product otoacoustic emissions in cases of abnormal distortion product otoacoustic emission findings for conventional frequencies related to the middle-ear condition.MethodThe present study investigated distortion product otoacoustic emission input–output functions in conventional and ultra-high frequencies in: 37 adults with chronic suppurative otitis media (clinical group) and 37 adults with normal hearing sensitivity (control group).ResultsThere were significant reductions in distortion product otoacoustic emission amplitude and mean signal-to-noise ratio in the clinical group compared to the control group, especially for conventional frequencies.ConclusionThere was a significant reduction in the rate of ears with measurable distortion product otoacoustic emissions in the clinical group, especially for conventional frequencies. The effect of chronic suppurative otitis media was more pronounced in the conventional frequency range compared to the smaller effect seen in the ultra-high frequency range.

Effects of spontaneous otoacoustic emissions on distortion product otoacoustic emission

2001 ◽  
Vol 28 ◽  
pp. S33-S38 ◽  
Author(s):  
Tsutomu Kuroda ◽  
Satoshi Fukuda ◽  
Eiji Chida ◽  
Masaaki Kashiwamura ◽  
Michiya Matsumura ◽  
...  
Keyword(s):  
Otoacoustic Emissions ◽  
Otoacoustic Emission ◽  
Distortion Product Otoacoustic Emission ◽  
Spontaneous Otoacoustic Emissions ◽  
Distortion Product

scholarly journals Distortion Product Otoacoustic Emissions (DPOAEs) In Tinnitus Patients

2021 ◽  
Author(s):  
Hend F. Alshabory ◽  
Takwa A. Gabr ◽  
Mona A. Kotait
Keyword(s):  
Otoacoustic Emissions ◽  
Direct Consequence ◽  
Normal Hearing ◽  
Distortion Product Otoacoustic Emissions ◽  
Control Group ◽  
Study Group ◽  
Input Output ◽  
Sound Stimulation ◽  
Hearing Sensitivity ◽  
Distortion Product

Abstract Introduction Tinnitus is the perception of sound in the absence of external sound stimulation. There is a general agreement that it is a direct consequence of irreversible and permanent cochlear damage. Objectives The present work is designed to study the distortion product otoacoustic emissions (DPOAEs) in tinnitus patients with normal hearing in comparison with normal hearing control and to study any possible correlation between DPOAEs recording and patients' complaints. Methods The present study included 80 subjects divided into 2 groups: Control group: consisted of 30 normal-hearing adults not complaining of tinnitus and Study group: consisted of 50 normal-hearing adults complaining of tinnitus. The methodology includes full audiological history, otoscopic examination, basic audiological evaluation, DPOAEs including both DP-gram and DPOAEs input/output functions. Results Basic audiological evaluation showed within normal hearing sensitivity in both groups, however, with significant higher hearing thresholds in tinnitus patients at all frequency ranges. The Tinnitus Handicap Inventory Questionnaire showed mean scores of 35.2 ± 16.9 in the study group. The DP-gram showed higher amplitudes in the control group when compared with tinnitus patients. The DPOAEs input-output functions at different frequencies (1, 2, 4 and 6kHz) also showed higher amplitudes at all frequencies and different input levels. The slope of the I/O function tends to be steeper in tinnitus cases. Conclusion Patients with tinnitus might have neural dysfunction at either the level of the cochlea, as shown in reduced DPOAE levels, and changes in the normal DP-I/O function recorded in the present work.

scholarly journals Estimation of outer hair cells function in chronic bilateral tinnitus patients with normal hearing using distortion product otoacoustic emissions

2021 ◽  
Author(s):  
Aras Karimiani ◽  
Nematollah Rouhbakhsh ◽  
Farzaneh Zamiri Abdollahi ◽  
Shohreh Jalaie
Keyword(s):  
Hair Cells ◽  
Otoacoustic Emissions ◽  
Normal Hearing ◽  
Outer Hair Cells ◽  
Distortion Product Otoacoustic Emissions ◽  
Control Group ◽  
Distortion Product Otoacoustic Emission ◽  
Frequency Range ◽  
Cochlear Function ◽  
Distortion Product

Background and Aim: It is not clear if the measurement of distortion product otoacoustic emissions (DPOAE) at frequencies above 8 kHz adds any value in determining the differences in the cochlear function between patients with and without tinnitus. This study aimed to compare DPOAE in the frequency range of 0.5−10 kHz in patients with normal hearing with and without tinnitus. Methods: This comparative cross-sectional study was conducted on 20 individuals with tinnitus and normal hearing as a study group (SG) and a control group (CG) of 20 normal-hearing individuals without tinnitus. The DPOAE was measured with F1/F2 = 1.22 and intensities of F1 = 65 dB SPL and F2 =55 dB SPL in the frequency range of 0.5−10 kHz, moreover in the frequency of tinnitus in SG and corresponding frequency in CG. Results: DPOAE level at 10 kHz did not differ significantly between SG and CG (p = 0.491). However, the mean of overall DPOAE level, DPOAE level at the frequency of tinnitus, and F2 values of 2.5, 5, and 6.298 kHz were significantly lower in SG than CG (p < 0.05). Conclusion: Measurement of DPOAE at 10 kHz did not seem to add any value in determining the differences in the cochlear function between patients with and without tinnitus. However, decreased DPOAE levels at 2.5, 5, and 6.298 kHz which were observed among patients who have tinnitus and normal hearing, indicates some outer hair cells damage that was not detectable by conventional audiometry. Keywords: Tinnitus; normal hearing; outer hair cell; distortion product otoacoustic emission

scholarly journals Otoacoustic emissions and biomarkers of oxidative stress in students of a tobacco-producing region

CoDAS ◽  
2014 ◽  
Vol 26 (3) ◽  
pp. 219-225 ◽  
Author(s):  
Letícia Regina Kunst ◽  
Michele Vargas Garcia ◽  
Alencar Kolinski Machado ◽  
Fernanda Barbisan ◽  
Aron Ferreira da Silveira
Keyword(s):  
Oxidative Stress ◽  
Otoacoustic Emissions ◽  
Micronucleus Test ◽  
Normal Hearing ◽  
Control Group ◽  
Response Level ◽  
Distortion Product ◽  
Significant Difference ◽  
The Mean ◽  
Biomarkers Of Oxidative Stress

PURPOSE: To verify the association between the amplitude of distortion-product otoacoustic emissions (DPOAE) and biomarkers of oxidative stress (OS) in resident students of the tobacco-producing region. METHODS: Participated in the study group (SG) 21 normal-hearing students from the tobacco-producing region, and in the control group (CG) 25 normal-hearing students who did not live in the countryside. The auditory system was assessed by DPOAE and the following biomarkers: dichlorofluorescein diacetate (DCFH-DA) and micronucleus test (MN). RESULTS: Both groups showed DPOAE present in both ears. Significant difference was detected between groups - in the right ear in the frequency of 4.000 Hz and in the left ear in the frequency of 2.000 Hz - with the mean amplitude of the DPOAE of the SG lower than the one found in the CG. Considering both ears, the SG presented lower mean across all frequencies and it was found a significant difference in the frequencies of 2.000 and 4.000 Hz. The overall mean of DPOAE, by ear, no significant differences were observed. In relation to the rate of production of free radicals, the mean of the SG was significantly higher than that of the mean of the CG. For the frequency of abnormal cells in the MN test, the mean of the SG was also considerate significantly higher than the mean of the CG. CONCLUSION: The SG showed a lower response level of DPOAE at all frequencies and high levels of biomarkers of EO, however there was no association between assessments.

Exploring Optimal Stimulus Frequency Ratio for Measurement of the Quadratic f 2 –f 1 Distortion Product Otoacoustic Emission in Humans

2018 ◽  
Vol 61 (7) ◽  
pp. 1794-1806
Author(s):  
Rachael R. Baiduc ◽  
Sumitrajit Dhar
Keyword(s):  
Otoacoustic Emissions ◽  
Endolymphatic Hydrops ◽  
Stimulus Frequency ◽  
Otoacoustic Emission ◽  
Normal Hearing ◽  
Distortion Product Otoacoustic Emission ◽  
Clinical Implementation ◽  
Distortion Product ◽  
Recent Interest ◽  
Stimulus Parameters

Purpose Distortion product otoacoustic emissions (DPOAEs) are a by-product of active cochlear processes that lead to the compressive nonlinearity of healthy ears. The most commonly studied emission is at the frequency 2f 1 –f 2 , but there has been recent interest in using the quadratic distortion product at the frequency f 2 –f 1 to detect cochleopathies including endolymphatic hydrops. Before the DPOAE at f 2 –f 1 can be applied clinically in any capacity, optimal stimulus parameters for its elicitation must be established. Method We investigated stimulus parameters for the DPOAEs at f 2 –f 1 and 2f 1 –f 2 in 23 adults with normal hearing. Logarithmically swept tones between approximately 0.6 and 20 kHz (L 1 = L 2 = 70 dB SPL) served as the higher frequency stimulus (f 2 ). DPOAEs were measured for 6 f 2 /f 1 ratios: 1.14, 1.18, 1.22, 1.30, 1.32, and 1.36. Results Both DPOAEs were consistently measurable. In line with previous investigations, the highest levels of the DPOAE at 2f 1 –f 2 were generated between f 2 /f 1 ratios of 1.14–1.22, with a peak in the level ratio function at 1.22. In contrast, f 2 –f 1 was less influenced by ratio, although the narrowest ratio (1.14) produced slightly higher levels across frequency. Conclusion The DPOAE at f 2 –f 1 is measurable in individuals with normal hearing up to f 2 of 20 kHz at narrow f 2 /f 1 ratios. Measurements at additional stimulus levels and in subjects with hearing impairment will be needed before clinical implementation.

Effect of mastoid drilling on hearing of the contralateral ear

2013 ◽  
Vol 127 (10) ◽  
pp. 952-956 ◽  
Author(s):  
A Goyal ◽  
P P Singh ◽  
A Vashishth
Keyword(s):  
Hearing Loss ◽  
High Frequency ◽  
Otoacoustic Emissions ◽  
Pure Tone Audiometry ◽  
Otoacoustic Emission ◽  
Prospective Clinical Study ◽  
Distortion Product Otoacoustic Emission ◽  
High Frequencies ◽  
Distortion Product ◽  
Contralateral Ear

AbstractObjectives:This study aimed to: understand the effect that high intensity noise associated with drilling (during otological surgery) has on hearing in the contralateral ear; determine the nature of hearing loss, if any, by establishing whether it is temporary or persistent; and examine the association between hearing loss and various drill parameters.Methods:A prospective clinical study was carried out at a tertiary centre. Thirty patients with unilateral cholesteatoma and normal contralateral hearing were included. Patients were evaluated pre-operatively and for five days following surgery using high frequency pure tone audiometry, and low and high frequency transient evoked and distortion product otoacoustic emission testing.Results:The findings revealed statistically significant changes in distortion product otoacoustic emissions at high frequencies (p = 0.016), and in transient evoked otoacoustic emissions at both low and high frequencies (p = 0.035 and 0.021, respectively). There was a higher statistical association between otoacoustic emission changes and cutting burrs compared with diamond burrs.Conclusion:Drilling during mastoid surgery poses a threat to hearing in the contralateral ear due to noise and vibration conducted transcranially.

Sign in / Sign up

Export Citation Format

Share Document