Should adults with isolated serous otitis media be undergoing routine biopsies of the post-nasal space?

2020 ◽  
Vol 134 (9) ◽  
pp. 811-813
Author(s):  
H A Cunniffe ◽  
A K Gona ◽  
J S Phillips
Keyword(s):  
Retrospective Study ◽  
Otitis Media ◽  
Otitis Media With Effusion ◽  
Clinical Findings ◽  
Endoscopic Examination ◽  
Referral Centre ◽  
Tertiary Referral Centre ◽  
Tube Dysfunction ◽  
Serous Otitis Media ◽  
Robust Evidence

AbstractBackgroundSerous otitis media is a recognised presentation of Eustachian tube dysfunction secondary to post-nasal space pathology. Post-nasal space biopsies are commonly taken in patients with isolated serous otitis media, despite normal nasendoscopy findings, without robust evidence for doing so. This study examined cases of unilateral serous otitis media with effusion in adults. It is the largest known retrospective study to investigate whether post-nasal space biopsies are indicated in non-endemic regions.MethodsA retrospective analysis was performed of 119 patients who underwent post-nasal space biopsy because of isolated serous otitis media, in a tertiary referral centre, from 2007 to 2017. Endoscopic examination and final histological report findings were reviewed.ResultsOf the 119 patients identified, 6 (5.0 per cent) were found to have abnormal histology. In all six cases, suspicious clinical findings had been noted on nasendoscopic examination prior to biopsy.ConclusionSuspicious findings pre-operatively predict sinister pathology. Biopsies are not recommended in cases of adult serous otitis media with normal nasendoscopy findings if no other risk factors exist. A UK-wide retrospective study or prospective study over the next 10 years will help provide the evidence necessary to support this guidance.

scholarly journals ATOPY, RISK FACTOR FOR OTITIS MEDIA WITH EFFUSION

2016 ◽  
Vol 65 (2) ◽  
pp. 174-176
Author(s):  
Ileana Ioniuc ◽  
◽  
Aurica Rugina ◽  
Alina Murgu ◽  
Irina Criscov ◽  
...  
Keyword(s):  
Gastroesophageal Reflux ◽  
Otitis Media ◽  
Otitis Media With Effusion ◽  
Acute Otitis Media ◽  
Allergic Diseases ◽  
Pediatric Clinic ◽  
Major Implication ◽  
Tube Dysfunction ◽  
Serous Otitis Media

Chronic otitis, one of the major causes of pediatric hypoacusia is frequent associated with some allergic diseases. The continuous rice of atopic diseases prevalence in childhood, involves a multidisciplinary approach of Eustachian tube dysfunction, adenoid inflammation or recurrent otitis, for a complex pathogenic management. The objective of this study was to determinate the association between otitis media and the allergic diseases with the implication in the treatment and evolution of this patients. Methods. Retrospective study on 92 children, between 6 month and 6 years, admitted in II Pediatric Clinic, Clinical Hospital of Children “Sf. Maria” Iasi with diagnosis of acute otitis media, for a period of 1 year. Results. Majority of cases (61patients) have been suppurate otitis, 31 cases have been otitis media with effusion out of which 23 have been recurrent. Association with allergic diseases has been more frequent in children with serous otitis media (26/31 cases). 4 cases with suppurate otitis media have developed adverse reaction to antibiotics with major implication in the cases evolution. Association with gastroesophageal reflux was relatively similar between cases with serous otitis and the suppurate ones (10/31 cases and 11/61 cases). From the atopic patients with gastroesophageal reflux, 10 presented cow’s milk protein allergy. In conclusion, the children with otitis media, especially those with recurrent none suppurate form should be investigated for atopy and, eventually, for gastroesophageal reflux, possibly with determination of the allergic markers or of pepsin in the otic exudates, in order to a targeted therapeutic management.

scholarly journals Effects of COVID-19 Lockdown on Otitis Media With Effusion in Children: Future Therapeutic Implications

2021 ◽  
pp. 019459982098745
Author(s):  
Mirko Aldè ◽  
Federica Di Berardino ◽  
Paola Marchisio ◽  
Giovanna Cantarella ◽  
Umberto Ambrosetti ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Otitis Media ◽  
Outpatient Clinic ◽  
Otitis Media With Effusion ◽  
Tertiary Level ◽  
Vestibular Disorders ◽  
Therapeutic Implications ◽  
History Of ◽  
Clinic Population

Objective To evaluate the role of social isolation during the lockdown due to the SARS-CoV-2 outbreak (severe acute respiratory syndrome coronavirus 2) in modifying the prevalence of otitis media with effusion (OME) and the natural history of chronic OME. Study Design Retrospective study. Setting Tertiary level referral audiologic center. Methods We assessed the prevalence of OME among children aged 6 months to 12 years who attended the outpatient clinic for hearing or vestibular disorders during 2 periods before the lockdown, May-June 2019 (n = 350) and January-February 2020 (n = 366), and the period immediately after the lockdown, May-June 2020 (n = 216). We also compared the disease resolution rates between a subgroup of children with chronic OME (n = 30) who were diagnosed in summer 2019 and reevaluated in May-June 2020 and a similar subgroup (n = 29) assessed in 2018-2019. Results The prevalence of OME in this clinic population was 40.6% in May-June 2019, 52.2% in January-February 2020, and 2.3% in May-June 2020. Children with chronic OME had a higher rate of disease resolution in May-June 2020 (93.3%) than those examined in May-June 2019 (20.7%, P < .001). Conclusion Closure of schools and the physical distancing rules were correlated with a reduction in the prevalence of OME and favored the resolution of its chronic forms among children who attended the outpatient clinic. These data could suggest that in the presence of chronic OME, keeping young children out of group care settings for a period might be beneficial to allow for OME resolution.

Relationship between Eustachian tube dysfunction and otitis media with effusion in radiotherapy patients

2018 ◽  
Vol 132 (2) ◽  
pp. 111-116 ◽  
Author(s):  
K Akazawa ◽  
H Doi ◽  
S Ohta ◽  
T Terada ◽  
M Fujiwara ◽  
...  
Keyword(s):  
Radiation Dose ◽  
Otitis Media ◽  
Eustachian Tube ◽  
Otitis Media With Effusion ◽  
Intensity Modulated Radiotherapy ◽  
Eustachian Tube Dysfunction ◽  
Dose Volume ◽  
Tube Dysfunction ◽  
The Relationship ◽  
Higher Doses

AbstractObjective:This study evaluated the relationship between radiation and Eustachian tube dysfunction, and examined the radiation dose required to induce otitis media with effusion.Methods:The function of 36 Eustachian tubes in 18 patients with head and neck cancer were examined sonotubometrically before, during, and 1, 2 and 3 months after, intensity-modulated radiotherapy. Patients with an increase of 5 dB or less in sound pressure level (dB) during swallowing were categorised as being in the dysfunction group. Additionally, radiation dose distributions were assessed in all Eustachian tubes using three dose–volume histogram parameters.Results:Twenty-two of 25 normally functioning Eustachian tubes before radiotherapy (88.0 per cent) shifted to the dysfunction group after therapy. All ears that developed otitis media with effusion belonged to the dysfunction group. The radiation dose threshold evaluation revealed that ears with otitis media with effusion received significantly higher doses to the Eustachian tubes.Conclusion:The results indicate a relationship between radiation dose and Eustachian tube dysfunction and otitis media with effusion.

Ocular Cysticercosis — A Profile

2003 ◽  
Vol 33 (3) ◽  
pp. 185-188 ◽  
Author(s):  
Anuradha Chowdhary ◽  
Rajlakshmi Bansal ◽  
Kirti Singh ◽  
Varinder Singh
Keyword(s):  
Retrospective Study ◽  
Medical Treatment ◽  
Surgical Excision ◽  
North India ◽  
Age Group ◽  
Common Site ◽  
Referral Centre ◽  
Tertiary Referral ◽  
Tertiary Referral Centre ◽  
Ocular Cysticercosis

A retrospective study was conducted on all histopathologically proven cases of ocular cysticercosis spanning a decade in a tertiary referral centre of North India. The symptomatology, presentation, complications and treatment therapies of 18 of these patients are discussed. The most common age group to be affected was 11–20 years (50%), while the most common site involved was subconjunctival (78%), followed by lid (11%). Spontaneous extrusion was documented in three cases. Medical treatment with albendazole under the cover of corticosteroids was found to be a useful adjunct to surgical excision.

scholarly journals Otitis media with effusion in Southwestern Region of Saudi Arabia

2013 ◽  
Vol 19 (1) ◽  
pp. 36-40
Author(s):  
Ali Maeed S Al-Shehri ◽  
Fach Arzt Ahmad Neklawi ◽  
Ayed A Shati ◽  
Ali M Alsuheel ◽  
Saleh M Al-Qahtani ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Saudi Arabia ◽  
Academic Performance ◽  
Retrospective Study ◽  
Medical Treatment ◽  
Otitis Media ◽  
Otitis Media With Effusion ◽  
Hearing Threshold ◽  
Preschool Age ◽  
Treatment Methods

Aim of Study: To determine effectiveness of myringotomy and grommet insertion (MGI) for patients with otitis media with effusion (OME), who failed medical treatment. Methods: A retrospective study was done on 86 patients who underwent MGI for OME between 2005 to 2010. Result: Age of patients ranged from 1 to 12 years, most of them (72%) were less than 6 years old. In children with OME, hearing and academic performance improved after grommet insertion. Conclusion: OME is mainly a disease of preschool age. The leading presenting complaint is hearing loss. MGI is important to be done if medical treatment failed. Hearing threshold improves significantly postoperatively. DOI: http://dx.doi.org/10.3329/bjo.v19i1.14861 Bangladesh J Otorhinolaryngol 2013; 19(1): 36-40

Adult-onset otitis media with effusion: results following ventilation tube insertion

2001 ◽  
Vol 115 (11) ◽  
pp. 874-878 ◽  
Author(s):  
M. W. Yung ◽  
R. Arasaratnam
Keyword(s):  
Otitis Media ◽  
Otitis Media With Effusion ◽  
Previous History ◽  
Endoscopic Examination ◽  
Lateral Nasal Wall ◽  
Adult Onset ◽  
Ventilation Tube ◽  
Tube Insertion ◽  
Prick Test ◽  
History Of

The outcome of otitis media with effusion (OME) in children is generally good. However, it is less clear in adults. All adult patients who had a ventilation tube inserted for OME at the Ipswich Hospital between 1996 and 1997 were studied. Of 53 patients studied, 28 had had a previous history of ventilation tube insertion. Furthermore, at 15–27 months following ventilation tube insertion, the ventilation tube had already extruded in 31 patients and the OME had already recurred in 19 of these. Endoscopic examination revealed that many patients still had evidence of inflammation at the lateral nasal wall (26.4 per cent) and at the eustachian tube orifice (51 per cent). There is also a strong history of atopy in the studied group and the skin prick test was positive in 57 per cent of the patients. This study shows that many patients with adult-onset OME have underlying pathology that could lead to recurrence of OME following ventilation tube extrusion.

Otitis Media with Effusion

1978 ◽  
Vol 87 (2) ◽  
pp. 191-196 ◽  
Author(s):  
M. Persico ◽  
L. Podoshin ◽  
M. Fradis
Keyword(s):  
Otitis Media ◽  
Eustachian Tube ◽  
Otitis Media With Effusion ◽  
Surface Active Agent ◽  
Combined Treatment ◽  
Active Agent ◽  
Systemic Steroid ◽  
Tube Dysfunction ◽  
Chemotherapeutic Treatment ◽  
The One

Eustachian tube dysfunction has been considered the main factor in the etiology of otitis media with effusion (OME). A short-term systemic steroid therapy, with combined chemotherapeutics, yielded 53.1% cure in 160 children in which OME had been diagnosed, whereas only 12.5% of similar 116 children were cured by chemotherapeutic treatment alone. It is postulated that steroids, acting by a mechanism much similar to the one in the newborn lung, increase the level of a tubal surface active agent, thus enhancing Eustachian tube refunctioning. This combined treatment, we believe, deserves its place as a routine conservative trial before surgery.

Refractory otitis media with effusion from viewpoints of eustachian tube dysfunction and nasal sinusitis

1993 ◽  
Vol 14 (3) ◽  
pp. 187-190 ◽  
Author(s):  
Akihiko Fujita ◽  
Iwao Honjo ◽  
Kyosuke Kurata ◽  
I-Ken Gan ◽  
Haruo Takahashi
Keyword(s):  
Otitis Media ◽  
Eustachian Tube ◽  
Otitis Media With Effusion ◽  
Eustachian Tube Dysfunction ◽  
Tube Dysfunction

Antibody Activity in Otitis Media with Effusion

1979 ◽  
Vol 88 (3) ◽  
pp. 392-396 ◽  
Author(s):  
Daniel M. Lewis ◽  
Herbert G. Birck ◽  
James L. Schram ◽  
David J. Lim
Keyword(s):  
Otitis Media ◽  
Otitis Media With Effusion ◽  
Bacterial Species ◽  
Disease Process ◽  
Antibody Activity ◽  
Igg Antibodies ◽  
Iga Antibodies ◽  
Antibody Method ◽  
Serous Otitis Media ◽  
Immunofluorescence Antibody

Bacteria were isolated from a high percentage of the effusions from patients with otitis media with effusion (OME, serous otitis media). In an attempt to determine if the isolated bacteria were involved in the disease process, we analyzed the serum and effusion of 25 OME patients for the presence of antibacterial antibodies by the indirect immunofluorescence antibody method. Specific antibody activity was detected in 20 of 25 effusions (80%) and 19 of 22 sera (86%). IgG antibodies were the most frequently found class of antibodies in both sera and effusions, but IgA antibodies were detected more frequently in the effusions than in the sera. Hemophilus influenzae, Streptococcus pneumoniae, and diphtheroids were the most frequently isolated organisms, and antibody activity to all bacterial species isolated was detected. The results support the concept that the isolated bacteria are not contaminants but are actively involved in the disease process.

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