Neurophysiological correlates of senile dementia: II. The somatosensory evoked response

1971 ◽  
Vol 1 (2) ◽  
pp. 159-165 ◽  
Author(s):  
Raymond Levy ◽  
Anthony Isaacs ◽  
Joan Behrman

SYNOPSISSpecific cortical somatosensory evoked responses were recorded in nine patients suffering from senile dementia and eight elderly depressed patients. The results were as follows. (1) The latencies of each peak were longer in the demented than in the depressed group but this difference was significant only for peak 3 (the second negative deviation). (2) The late negative deviation (peak 5) was either absent or very flat in demented patients. The ratio of the amplitude of this late wave to that of the first peak discriminated between demented and non-demented patients at the 0·5% level. (3) The value of this ratio combined with that of the latency of peak 3 could be used to classify all but one patient into the correct diagnostic group. The results are discussed in the light of the relevant literature. It is suggested that slowing of conduction in the nervous system may be a very basic disturbance associated with cognitive impairment in old age and that measurements of this kind may come to assist in the diagnosis of dementia.

2002 ◽  
Vol 14 (2) ◽  
pp. 123-126 ◽  
Author(s):  
Conor P. Maguire

Pinner and Bouman's review article “To Tell or Not to Tell: On Disclosing the Diagnosis of Dementia” (pp. 127–137 in this issue) outlines the pros and cons of diagnosis disclosure to this diagnostic group. It is only over the past 10 years that the question of informing patients with dementia of their diagnosis has become topical, although the hard evidence for and against telling remains sparse, with much of the argument on either side being anecdotal. Paternalism is a common theme of surveys that examine the attitudes of spouse caregivers, relatives, and nonaffected older adults toward telling the diagnosis of dementia (Connell & Gallant, 1996; Erde et al., 1988; Holroyd et al., 1996; Maguire et al., 1996).


Author(s):  
Ineta Balode ◽  
Dzintra Lele-Rozentāle

Dementia is a condition observed in persons afflicted with different brain diseases, first of all, with Alzheimer’s Disease. Alzheimer’s is the most common type of senile dementia. Limited cognitive and lingual capacity and other problems make the affected persons dependent on medical and social help. With the progression of the disease, the economic burden becomes heavy both for the family and society. So far, no effective medical treatment has been discovered, which could stop the decrease in brain capacity. However, early diagnosis of dementia symptoms is important because alternative individual preventive instruments can be implemented to slow down the progression of the disease and prolong the period of the relatively independent existence of patients. The worldwide known MoCA test is one of the most common instruments for testing persons worried about their mental condition and cognitive capacities. The test is translated and partially adapted in several languages, including Latvian. Our analysis was aimed at the question: does the Latvian test version respond to the requirements which are necessary to achieve optimal results. In other words, can it provide an objective rating of a lingual performance by the tested persons? The first critical inventory concerned three relevant parts: the formulation of tasks, the prescribed instructions, and the principles of interpretation of testing results. Several examples demonstrate that some deficits can be observed in all the analysed parts. Some tasks should be better adapted to the Latvian situation so that a lingual or cognitive test would be separated from the test of the-so-called world knowledge. The instructions should be formulated clearly, without using complicated grammatical structures (currently, some of them are more complicated than the tasks), and they should focus on the tasks instead of examiners’ activities. In some cases, the suggested interpretation principles of the test results cannot be seen as reasoned from the linguistic point of view. Some observations indicate that the translation of the test and its requirements or instructions were carried out by a person who does not deal professionally with linguistics. The main conclusion is that the current quality of the Latvian MoCA test needs a critical review and, possibly, complete revision. Thus, the interdisciplinary cooperation between linguists and physicians, as well as joint research, is an actual and necessary precondition for the improvement of health care in Latvia.


2021 ◽  
Vol 80 (2) ◽  
pp. 619-637
Author(s):  
Jessica Grothe ◽  
Georg Schomerus ◽  
Jens Dietzel ◽  
Steffi Riedel-Heller ◽  
Susanne Röhr

Background: Social functioning is an important parameter for the early detection and diagnosis of dementia, as well as the description of its course and the assessment of intervention effects. Therefore, valid and reliable instruments to measure social functioning in individuals with dementia are needed. Objective: We aimed to provide an overview of such instruments including information on feasibility and psychometric properties. Methods: The review is informed by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Relevant literature was identified using a pre-specified search string in the databases MEDLINE, PsycINFO, and Web of Science. Information on the characteristics, feasibility, and psychometric properties of the identified instruments were extracted, summarized, and discussed. Results: Out of 5,307 articles, 8 were selected to be included in the study, describing a total of three instruments for measuring social functioning in individuals with dementia: the Nurses’ Observation Scale for Geriatric Patients (NOSGER; dimension “social behavior”), the Socioemotional Dysfunction Scale (SDS), and the Social Functioning in Dementia Scale (SF-DEM). The validity of all the three instruments was overall acceptable. Reliability was high for the NOSGER scale “social behavior” and the SF-DEM. Information on the usability of the instruments tended to be scarce. Conclusion: There are a few valid and reliable instruments to assess social functioning in individuals with dementia. Further considerations could comprise their feasibility with regard to measuring changes in social functioning over time, in additional target groups, e.g., different types and stages of dementia, and adaptions to different languages and cultural backgrounds.


1968 ◽  
Vol 2 (4) ◽  
pp. 264-271 ◽  
Author(s):  
G. Vernon Davies

This paper is a summary of an investigation into family relationships of 200 elderly patients admitted consecutively to the Mont Park Mental Hospital, Melbourne, in 1965–66. From the study, some data of statistical significance concerning social aspects of mental disorders of late life were obtained. Most of these data concerned senile dementia, which was the diagnostic group to which one-third of the patients was allotted. The survey was the basis for a thesis submitted to the Department of Psychiatry in the University of Melbourne for the degree of Doctor of Philosophy.


Perception ◽  
1977 ◽  
Vol 6 (1) ◽  
pp. 85-95 ◽  
Author(s):  
Denis M Parker ◽  
Eric A Salzen

Two studies on the amplitude, latency, and waveform of human visual evoked responses to the onset of sine-wave grating patterns were made. Results indicated that the peak latencies of both early and late waves were a function of the spatial frequency of the stimulus. The amplitude of the early wave (N1−P1) was consistently greatest at low spatial frequencies while the late wave (N2−P2) showed consistent attenuation at low spatial frequencies. In addition the location of the peak amplitude response of the late, but not the early, wave depended on the location (macular versus extramacular) and area (small versus large stimulus field) of retina stimulated. These findings are discussed in the light of evidence for separate transient and sustained systems within the human visual system.


1968 ◽  
Vol 11 (2) ◽  
pp. 334-342 ◽  
Author(s):  
Gretchen B. Henry ◽  
Donald C. Teas

Averaged evoked responses to noise burst signals at six sensation levels were obtained in three experimental contexts and compared on the basis of response magnitude. No significant effects were found related to context; systematic differences were found, however, within the ensemble of responses making up the average. These differences suggest that the maximum estimate of response magnitude may be contained in the first few responses to a series of stimuli.


GeroPsych ◽  
2020 ◽  
Vol 33 (4) ◽  
pp. 246-251
Author(s):  
Gozde Cetinkol ◽  
Gulbahar Bastug ◽  
E. Tugba Ozel Kizil

Abstract. Depression in older adults can be explained by Erikson’s theory on the conflict of ego integrity versus hopelessness. The study investigated the relationship between past acceptance, hopelessness, death anxiety, and depressive symptoms in 100 older (≥50 years) adults. The total Beck Hopelessness (BHS), Geriatric Depression (GDS), and Accepting the Past (ACPAST) subscale scores of the depressed group were higher, while the total Death Anxiety (DAS) and Reminiscing the Past (REM) subscale scores of both groups were similar. A regression analysis revealed that the BHS, DAS, and ACPAST predicted the GDS. Past acceptance seems to be important for ego integrity in older adults.


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