OP242 Patient-based Evidence: A Comparison Of The Views Of Patient And Clinical Engagement Participants And Committee Members

2021 ◽  
Vol 37 (S1) ◽  
pp. 8-8
Author(s):  
Sharon Hems ◽  
Louise Taylor ◽  
Jan Jones ◽  
Eileen Holmes
Keyword(s):  
Decision Making ◽  
Rank Order ◽  
Health Benefits ◽  
Treatment Choice ◽  
Added Value ◽  
Normal Life ◽  
Early Health Technology Assessment ◽  
The Future ◽  
Early Health ◽  
Clinical Engagement

IntroductionThe Scottish Medicines Consortium (SMC) conducts early health technology assessment (HTA) of new medicines on behalf of NHSScotland. Evidence from patients and carers on end-of-life and orphan medicines is gathered during Patient and Clinician Engagement (PACE) meetings. The output is a consensus statement describing a medicine's added value from the perspective of patients/carers and clinicians, which is used by SMC committee members in decision-making. This study compared the importance of factors in the PACE statement to PACE participants and committee members.MethodsA survey of ninety-eight PACE participants (consisting of forty-two patient group (PG) representatives and fifty-six clinicians) investigated the importance of quality of life (QoL) themes (family/carer impact, health benefits, tolerability, psychological benefit, hope, normal life, treatment choice and convenience) identified from an earlier thematic analysis of PACE statements. The findings from PG representatives and clinicians were compared, and the overall results were further compared with those from a previous survey of committee members (n = 26).ResultsAmong PACE participants who responded (twenty-six PG representatives and fourteen clinicians), 100 percent rated ‘health benefits’ and ‘ability to take part in normal life’ as important / very important. ‘Convenience of administration’ and ‘treatment choice’ received the lowest rating with fifteen percent and nineteen percent respectively of PG representatives versus seven percent of clinicians rating each as very important. ‘Hope for the future’ received the most diverse response with fifty-eight percent of PG representatives and fourteen of clinicians rating this as very important.In general, PACE participants rated importance of QoL themes higher than committee members (n = 21) but the rank order was similar. Differences between the proportion of PACE participants and committee members who rated themes important/very important was greatest for ‘treatment choice’ (sixty-seven percent versus twenty percent respectively) and ‘hope for the future’ (eighty-two percent versus fifty-three percent).ConclusionsThe findings demonstrate some alignment between PACE participants’ and committee members’ responses, supporting the value of the PACE output in decision-making. Areas for further research are highlighted.

scholarly journals The Potential Impact of Digital Biomarkers in Multiple Sclerosis in the Netherlands: An Early Health Technology Assessment of MS Sherpa

2021 ◽  
Vol 11 (10) ◽  
pp. 1305
Author(s):  
Sonja Cloosterman ◽  
Inez Wijnands ◽  
Simone Huygens ◽  
Valérie Wester ◽  
Ka-Hoo Lam ◽  
...  
Keyword(s):  
Cost Effective ◽  
Health Technology ◽  
Added Value ◽  
Early Health Technology Assessment ◽  
Early Health ◽  
Treatment Switch ◽  
Potential Impact ◽  
Digital Biomarkers ◽  
Care Path ◽  
Active Disease

(1) Background: Monitoring of Multiple Sclerosis (MS) with eHealth interventions or digital biomarkers provides added value to the current care path. Evidence in the literature is currently scarce. MS sherpa is an eHealth intervention with digital biomarkers, aimed at monitoring symptom progression and disease activity. To show the added value of digital biomarker–based eHealth interventions to the MS care path, an early Health Technology Assessment (eHTA) was performed, with MS sherpa as an example, to assess the potential impact on treatment switches. (2) Methods: The eHTA was performed according to the Dutch guidelines for health economic evaluations. A decision analytic MS model was used to estimate the costs and benefits of MS standard care with and without use of MS sherpa, expressed in incremental cost-effectiveness ratios (ICERs) from both societal and health care perspectives. The efficacy of MS sherpa on early detection of active disease and the initiation of a treatment switch were modeled for a range of assumed efficacy (5%, 10%, 15%, 20%). (3) Results: From a societal perspective, for the efficacy of 15% or 20%, MS sherpa became dominant, which means cost-saving compared to the standard of care. MS sherpa is cost-effective in the 5% and 10% scenarios (ICERs EUR 14,535 and EUR 4069, respectively). From the health care perspective, all scenarios were cost-effective. Sensitivity analysis showed that increasing the efficacy of MS sherpa in detecting active disease early leading to treatment switches be the most impactful factor in the MS model. (4) Conclusions: The results indicate the potential of eHealth interventions to be cost-effective or even cost-saving in the MS care path. As such, digital biomarker–based eHealth interventions, like MS sherpa, are promising cost-effective solutions in optimizing MS disease management for people with MS, by detecting active disease early and helping neurologists in decisions on treatment switch.

scholarly journals CONDITIONS OF INVESTMENT DECISION-MAKING IN AREA OF RFID TECHNOLOGY

2014 ◽  
Vol 2 ◽  
pp. 55-64
Author(s):  
Marzena Jankowska-Mihułowicz ◽  
Piotr Jankowski-Mihułowicz
Keyword(s):  
Decision Making ◽  
Radio Frequency Identification ◽  
Interdisciplinary Approach ◽  
Market Potential ◽  
Added Value ◽  
Simultaneous Estimation ◽  
Product Code ◽  
Electronic Product Code ◽  
Electronic Product ◽  
The Future

The application of the electronic product code (EPC) in an enterprise may turn out to be one of the choices in the future. The subject of this article is an analysis preceding decisive conditions in an investment process of its implementation. These reflections are preceded by the research in Polish enterprises, aiming at an estimation of the possibility of the RFID (Radio Frequency IDentification) transponder commercialisation (market potential) being consistent with the EPC requirements. Conducting such research in the future will lead to a decrease in the decision gap among managers within the scope of the possibility of implementing the innovative solution described, as well as the anticipated business results.  Methods of analysis and synthesis have been applied, within the theory of decision-making and telecommunications. An interdisciplinary approach to the issue in question constitutes the added value of this article.  The conclusion comprises a synthesis of the article contents—crucial decisive areas that require monitoring and simultaneous estimation (now and in the future) regarding implementation of the electronic product code in an organization. In general, these areas are macro environment, competitive environment, strategic potential of an organization, and managers’ decisiveness.

PEMILIHAN KEPLING TELADAN MENERAPKAN METODE RANK ORDER CENTROID (ROC) DAN METODE ADDITIVE RATIO ASSESSMENT (ARAS) DI KECAMATAN MEDAN AREA

2019 ◽  
Vol 3 (1) ◽  
Author(s):  
Liza Handayani ◽  
Muhammad Syahrizal ◽  
Kennedi Tampubolon
Keyword(s):  
Decision Making ◽  
Decision Support ◽  
Decision Support System ◽  
Support System ◽  
Rank Order ◽  
Priority Level ◽  
The Village ◽  
Field Area ◽  
Selection Of

The head of the environment is an extension of the head of the village head in assisting or providing services to the community both in the administration of administration in the village and to other problems. It is natural for a kepling to be appreciated for their performance during their special tenure in the kecamatan field area. Previously, the selection of a dipling in a sub-district was very inefficient and seemed unfair for this exemplary selection to use a system to produce an accurate value, and no intentional element. To overcome the process of selecting an exemplary kepling that experiences these obstacles by using an application called a Decision Support System. Decision Support System (SPK) is a system that can solve a problem, and this system is also assisted with several methods, namely the Rank Order Centroid (ROC) method that can assign weight values to each of the criteria based on their priority level. And to do the ranking or determine an exemplary set using the Additive Ratio Assessment (ARAS) method, this method provides decision making that takes decisions based on ranking or the highest value.Keywords: Head of Medan Area Subdistrict, SPK, Centroid Rank Order, Additive Ratio Assessment (ARAS).

FISCAL PESSIMISM IN HISTORICAL PERSPECTIVE: TOCQUEVILLE'S CROSS REVISITED

2021 ◽  
pp. 1-21
Author(s):  
Isabel Cepeda ◽  
Pedro Fraile Balbín
Keyword(s):  
Economic Growth ◽  
Decision Making ◽  
Political Economy ◽  
Historical Perspective ◽  
Income Redistribution ◽  
Government Control ◽  
Economic Decision ◽  
Modern School ◽  
Economic Decision Making ◽  
The Future

ABSTRACT This paper explores Alexis de Tocqueville's thought on fiscal political economy as a forerunner of the modern school of preference falsification and rational irrationality in economic decision making. A good part of the literature has misrepresented Tocqueville as an unconditional optimist regarding the future of fiscal moderation under democracy. Yet, although he initially shared the cautious optimism of most classical economists with respect to taxes under extended suffrage, Tocqueville's view turned more pessimistic in the second volume of his Democracy in America. Universal enfranchisement and democratic governments would lead to higher taxes, more intense income redistribution and government control. Under democracy, the continuous search for unconditional equality would eventually jeopardise liberty and economic growth.

Redisign of the Air Traffic Control System-Moving People through Distributed Management

1978 ◽  
Vol 22 (1) ◽  
pp. 485-485
Author(s):  
John G. Kreifeldt
Keyword(s):  
Decision Making ◽  
Control System ◽  
Traffic Control ◽  
Air Traffic Control ◽  
Negative Impact ◽  
Air Traffic ◽  
Critical Function ◽  
Congressional Hearings ◽  
The Future ◽  
Traffic Control System

The present national Air Traffic Control system is a ground-centralized, man intensive system which through design allows relatively little meaningful pilot participation in decision making. The negative impact of this existing design can be measured in delays, dollars and lives. The FAA's design plans for the future ATC system will result in an even more intensive ground-centralized system with even further reduction of pilot decision making participation. In addition, controllers will also be removed from on-line decision making through anticipated automation of some or all of this critical function. Recent congressional hearings indicate that neither pilots nor controllers are happy or sanguine regarding the FAA's design for the future ATC system.

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