scholarly journals Salivary Gland-Like Tumor of the Sella

2007 ◽  
Vol 34 (4) ◽  
pp. 478-482 ◽  
Author(s):  
Wouter van Furth ◽  
Harley S. Smyth ◽  
Eva Horvath ◽  
Kalman Kovacs ◽  
Fateme Salehi ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Case Report ◽  
Pituitary Adenomas ◽  
Biological Behavior ◽  
Benign Tumors ◽  
Sellar Region ◽  
Non Invasive ◽  
Medical Issues ◽  
Sellar Tumor ◽  
Pituitary Carcinomas

Tumors arising in the sellar region are predominantly benign, non-invasive pituitary adenomas. Invasive pituitary adenomas (approximately 35 % of the pituitary adenomas) and pituitary carcinomas (0.1 – 0.5 %) arise from the same cells in the pituitary gland as the benign tumors, but have different pathology and biological behavior. A wide variety of nonadenomatous lesions involve the sellar region. These include tumors that arise specifically from sellar and suprasellar structures, as well as those that are also found elsewhere in the CNS (e.g. meningioma, glioma, metastasis, etc.). Typical nonadenomatous tumors that originate in the sellar region are craniopharyngioma and Rathke’s cleft cyst. The purpose of this paper is to describe another nonadenomatous tumor specific to the sellar region, a salivary gland-like tumor, and review the literature on this subject. This case report will also illustrate the management decisions regarding a patient with multiple medical issues and an aggressive sellar tumor.

Intrasellar Paraganglioma with Suprasellar Extension: Case Report

1998 ◽  
Vol 84 (3) ◽  
pp. 408-411 ◽  
Author(s):  
Maria Laura Del Basso De Caro ◽  
Antonella Siciliano ◽  
Paolo Cappabianca ◽  
Alessandra Alfieri ◽  
Enrico de Divitiis
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Case Report ◽  
Pelvic Floor ◽  
The Body ◽  
Benign Tumors ◽  
Sellar Region ◽  
The Central Nervous System ◽  
Base Of The Skull ◽  
Suprasellar Extension

Paragangliomas are usually benign tumors which can be found in many sites of the body, from the base of the skull down to the pelvic floor. In the central nervous system the sellar region is very rarely involved; only three well studied cases have been reported to date. We present the cytological, histological, histochemical, immunocytochemical and ultrastructural features of an intrasellar and suprasellar paraganglioma in an 84-year-old man.

scholarly journals Benign tumors of the heart: Myxoma of the right atrium - a case report

2018 ◽  
Vol 75 (5) ◽  
pp. 512-515 ◽  
Author(s):  
Sasa Hinic ◽  
Jelena Saric ◽  
Predrag Milojevic ◽  
Jelena Gavrilovic ◽  
Tijana Durmic ◽  
...  
Keyword(s):  
Case Report ◽  
Body Position ◽  
Atrial Myxoma ◽  
Right Atrial ◽  
Benign Tumors ◽  
Non Invasive ◽  
Right Atrial Myxoma ◽  
The Right

Introduction. Myxoma is the most common primary benign heart tumor. The most frequent location is the left atrium, the chamber of the heart that receives oxygen- rich blood from the lungs. Myxomas usually develop in women, typically between the ages of 40 and 60. Symptoms may occur at any time, but most often they are asymptomatic or oligosymptomatic for a long period of time. Symptoms usually go along with body position, and are related to compression of the heart cavities, embolization and the appearance of general symptoms. The diagnosis of benign tumors of the heart is based on anamnesis, clinical features and findings of the tumor masses by use of non-invasive and invasive imaging methods. Extensive surgical resection of the myxoma is curative with minimal mortality. Long term clinical and echocardiographic follow-up is mandatory. Case report. We reported a case of a 62-year-old male, presented with 15 days of intermittent shortness of breath, dizziness and feeling of heart palpitations and subsequently diagnosed with right atrial myxoma based on transthoracic echocardiography . The patient was emergently operated in our hospital. Long-term followup did not reveal recurrence. Conclusion. Our case was an atypical localisation of right atrial myxoma. Whether the intracardiac mass is benign or malignant, early surgery is obligatory in order to prevent complications.

scholarly journals Intrasellar Chondroid Chordoma: A Case Report

2011 ◽  
Vol 2011 ◽  
pp. 1-5 ◽  
Author(s):  
Renata M. Hirosawa ◽  
Antonio B. A. Santos ◽  
Mariana M. França ◽  
Viciany Erique Fabris ◽  
Ana Valéria B. Castro ◽  
...  
Keyword(s):  
Case Report ◽  
Pituitary Adenomas ◽  
Bone Tumors ◽  
Bone Erosion ◽  
Sellar Region ◽  
Malignant Bone Tumors ◽  
Intracranial Neoplasms ◽  
Progressive Loss ◽  
Chondroid Chordoma ◽  
History Of

Chordomas are tumors derived from cells that are remnants of the notochord, particularly from its proximal and distal extremes, they are mainly midline and represent approximately 1% of all malignant bone tumors and 0.1 to 0.2% of intracranial neoplasms. Chordomas involving the sellar region are rare. Herein, we describe a 57-year-old male patient presenting with a history of retro-orbital headache, progressive loss of vision, and clinical features of hypopituitarism, for over 2 months. During evaluation, the CT scan revealed a large contrast-enhancing intrasellar tumor with a 3.6-cm largest diameter. The patient underwent transsphenoidal partial resection of the tumor, and histological examination was consistent with the diagnosis of chondroid chordoma. Although chordomas are rare, they may be considered to constitute a differential diagnostic of pituitary adenomas, especially if a calcified intrasellar tumor with bone erosion is diagnosed.

Treatment of Aggressive Pituitary Adenomas and Carcinomas – An Overview

2012 ◽  
Vol 7 (3) ◽  
pp. 178
Author(s):  
Luis V Syro ◽  
Leon D Ortiz ◽  
Fabio Rotondo ◽  
Humberto Uribe ◽  
Luis C Penagos ◽  
...  
Keyword(s):  
Growth Rate ◽  
Side Effects ◽  
Pituitary Adenomas ◽  
Treatment Options ◽  
Sella Turcica ◽  
Incomplete Resection ◽  
Pituitary Tumours ◽  
Non Invasive ◽  
Rapid Growth Rate ◽  
Pituitary Carcinomas

Most pituitary tumours are non-invasive, benign adenomas that remain confined to the sella turcica. Some of them recur, have a rapid growth rate, and invade surrounding tissues. These adenomas, considered aggressive pituitary tumours, are difficult to manage and present problems due to incomplete resection. A pituitary carcinoma is diagnosed when craniospinal and/or systemic metastases are documented. Treatment options for pituitary adenomas are surgery, radiation and drugs. Recent publications report the efficacy of temozolomide in the treatment of aggressive pituitary adenomas and carcinomas. Indications for, results with, and side effects of temozolomide therapy in aggressive pituitary tumours and pituitary carcinomas are reviewed here. Alternative treatment options for resistant or recurrent pituitary tumours are also discussed.

scholarly journals Comparative Proteomic Study Shows the Expression of Hint-1 in Pituitary Adenomas

Diagnostics ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 330
Author(s):  
Carolina Carrillo-Najar ◽  
Daniel Rembao-Bojórquez ◽  
Martha L. Tena-Suck ◽  
Sergio Zavala-Vega ◽  
Noemí Gelista-Herrera ◽  
...  
Keyword(s):  
Pituitary Adenomas ◽  
Biological Behavior ◽  
Ki 67 ◽  
Non Invasive ◽  
Proteomic Study ◽  
Neoplastic Process ◽  
Adenohypophyseal Hormones ◽  
Aggressive Tumors ◽  
Proteomic Map

Pituitary adenomas (PAs) can be unpredictable and aggressive tumors. No reliable markers of their biological behavior have been found. Here, a proteomic analysis was applied to identify proteins in the expression profile between invasive and non-invasive PAs to search for possible biomarkers. A histopathological and immunohistochemical (adenohypophyseal hormones, Ki-67, p53, CD34, VEGF, Flk1 antibodies) analysis was done; a proteomic map was evaluated in 64 out of 128 tumors. There were 107 (84%) invasive and 21 (16%) non-invasive PAs; 80.5% belonged to III and IV grades of the Hardy–Vezina classification. Invasive PAs (n = 56) showed 105 ± 43 spots; 86 ± 32 spots in non-invasive PAs (n = 8) were observed. The 13 most prominent spots were selected and 11 proteins related to neoplastic process in different types of tumors were identified. Hint1 (Histidine triad nucleotide-binding protein 1) high expression in invasive PA was found (11.8 ± 1.4, p = 0.005), especially at high index (>10; p = 0.0002). High Hint1 expression was found in invasive VEGF positive PA (13.8 ± 2.3, p = 0.005) and in Flk1 positive PA (14.04 ± 2.28, p = 0.006). Hint1 is related to human tumorigenesis by its interaction with signaling pathways and transcription factors. It could be related to invasive behavior in PAs. This is the first report on Hint expression in PAs. More analysis is needed to find out the possible role of Hint in these tumors.

Monomorphic Adenoma of Posterior Palate: A Rare Case Report

2021 ◽  
Author(s):  
Abhinav Sharma
Keyword(s):  
Salivary Gland ◽  
Case Report ◽  
Rare Case ◽  
Malignant Tumors ◽  
Minor Salivary Gland ◽  
Benign Tumors ◽  
Rare Entity ◽  
Present Case Report ◽  
Rare Case Report ◽  
Monomorphic Adenoma

Background: Minor salivary gland benign tumors account for a very small percentage of salivary gland tumors of which monomorphic adenomas are a rare entity. Methods and Findings: The present case report discusses a rare case report of an 18-year-old female patient diagnosed with monomorphic adenoma of the posterior palatal region. The diagnosis was reached after thorough radiographical and pathological investigations. Conclusion: Monomorphic Adenoma in a younger individual is a rare disorder and can be used as a collective term for benign or malignant tumors comprising of one type or even two types of cells.

Treatment of Aggressive Pituitary Adenomas and Carcinomas—An Overview

2012 ◽  
Vol 08 (01) ◽  
pp. 50
Author(s):  
Luis V Syro ◽  
Leon D Ortiz ◽  
Fabio Rotondo ◽  
Humberto Uribe ◽  
Luis C Penagos ◽  
...  
Keyword(s):  
Growth Rate ◽  
Side Effects ◽  
Pituitary Adenomas ◽  
Treatment Options ◽  
Sella Turcica ◽  
Pituitary Tumors ◽  
Incomplete Resection ◽  
Non Invasive ◽  
Rapid Growth Rate ◽  
Pituitary Carcinomas

Most pituitary tumors are non-invasive, benign adenomas that remain confined to the sella turcica. Some of them recur, have a rapid growth rate, and invade surrounding tissues. These adenomas, considered aggressive pituitary tumors, are difficult to manage and present problems due to incomplete resection. A pituitary carcinoma is diagnosed when craniospinal and/or systemic metastases are documented. Treatment options for pituitary adenomas are surgery, radiation, and drugs. Recent publications report the efficacy of temozolomide in the treatment of aggressive pituitary adenomas and carcinomas. Indications for, results with, and side effects of temozolomide therapy in aggressive pituitary tumors and pituitary carcinomas are reviewed here. Alternative treatment options for resistant or recurrent pituitary tumors are also discussed.

scholarly journals Canalicular Adenoma Presenting as an Asymptomatic Swelling of the Upper Lip: A Case Report

2008 ◽  
Vol 9 (1) ◽  
pp. 91-97 ◽  
Author(s):  
Luciana Reis Azevedo ◽  
Jean Nunes Dos Santos ◽  
Antônio Adilson Soares De Lima ◽  
Maria Ângela Naval Machado ◽  
Ana Maria Trindade Grégio
Keyword(s):  
Salivary Gland ◽  
Case Report ◽  
Basal Cell ◽  
Salivary Gland Tumor ◽  
Surgical Excision ◽  
Late Recurrence ◽  
World Health ◽  
Benign Tumors ◽  
Upper Lip ◽  
Cell Adenoma

Abstract Aim The purpose of this report is to present the clinical and histological features of a canalicular adenoma (CA) occurring in the upper lip and vestibular fornix of a 62-year-old woman. Background CA is an uncommon benign salivary gland tumor occurring almost exclusively in the intraoral glands. This tumor has often been referred to as a variant of the basal cell adenoma. However, the World Health Organization's latest histological classification of salivary gland tumors recognizes it as a separate entity under the broader heading of monomorphic adenoma, which is not related to any of the subtypes of basal cell adenomas. Case Report A 62-year-old woman with a chief complaint of an extraoral swelling in the upper lip. The evolution of the lesion was not known by the patient who recognized it when she touched her upper lip and found “an acne” on it. The patient wore complete dentures since age 17 and was not aware of any pain or tenderness in the area. Extra and intraoral examination revealed a mobile nodular lesion located in the right aspect of the upper lip near the nose and in the vestibular fornix between the lateral incisor and canine. Microscopic examination confirmed the final diagnosis of CA. The patient is currently free of disease 54 months after surgical excision of the tumor. Summary Local excision of symptomatic nodules seems to be sufficient to manage patients with multifocal CA.10 But, unlike other benign tumors, CA may need a longer follow-up due to its tendency towards multifocal occurrence and late recurrence.3,7 Citation Azevedo LR, Dos Santos JN, De Lima AAS, Machado MÂN, Grégio AMT. Canalicular Adenoma Presenting as an Asymptomatic Swelling of the Upper Lip: A Case Report. J Contemp Dent Pract 2008 January; (9)1:091-097.

Large Vulvar Lipoma in an Adolescent: A Case Report

JMS SKIMS ◽  
2011 ◽  
Vol 14 (1) ◽  
pp. 28-29
Author(s):  
R K Maurya ◽  
Pawan Kumar Singh ◽  
Sandeep Singh
Keyword(s):  
Case Report ◽  
Epithelial Cell ◽  
Adolescent Girl ◽  
Rare Case ◽  
Mesenchymal Cell ◽  
Benign Tumors ◽  
Melanocytic Tumors

Lipomas of vulva have been reported only rarely. Benign tumors of the vulva are normally classified according to their origin as epithelial cell tumors (e.g., keratinocytic, adnexal and ectopic tumors), or mesenchymal cell tumors (e.g., vascular, fibrous, muscular, neural, adipose and melanocytic tumors). Vulvar lipomas need to be differentiated from liposarcomas, which are rare but are very similar to lipomas clinically. Here we present a rare case of large vulvar lipoma in an adolescent girl. JMS 2011;14(1):28-29

Birt-Hogg-Dubé Syndrome: A Case Report Describing Sonographic Evaluation of Salivary Gland Oncocytomas

2019 ◽  
Vol 2 ◽  
pp. 5
Author(s):  
Kevin Kapcio ◽  
Kamila Skalski ◽  
Vikram Dogra
Keyword(s):  
Salivary Gland ◽  
Case Report ◽  
Renal Cell ◽  
Autosomal Dominant ◽  
Colonic Polyps ◽  
Sonographic Evaluation ◽  
Parathyroid Adenomas ◽  
Pulmonary Cysts ◽  
Renal Screening ◽  
Bhd Syndrome

Birt-Hogg-Dubé (BHD) syndrome is a rare hereditary disorder associated with autosomal dominant hereditary epithelial carcinomas, in which patients have an increased incidence of renal cell carcinomas, scattered hamartomas, pulmonary cysts, and spontaneous pneumothoraces. Other less common findings include lipomas, parathyroid adenomas, salivary gland tumors, and colonic polyps/tumors. Early diagnosis of BHD can help establish renal screening and reduce mortality by early detection and more effective treatment of renal cell carcinoma. This case report describes the sonographic features of salivary gland oncocytomas found in a patient with BHD.

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