Seroepidemiology ofToxoplasma gondiiinfection in the Israeli population

2013 ◽  
Vol 142 (1) ◽  
pp. 149-155 ◽  
Author(s):  
M. PERRY MARKOVICH ◽  
T. SHOHAT ◽  
I. RIKLIS ◽  
R. AVNI ◽  
D. YUJELEVSKI-ROZENBLIT ◽  
...  

SUMMARYToxoplasmosis seroprevalence varies considerably between countries. We studied the seoprevalence ofToxoplasma gondiiIgG antibodies in a national sample of the Israeli population; 2794 sera were tested. The highest age-adjusted seroprevalence rate was in Arabs (non-Bedouins) (60·4%), significantly higher compared to the rate in Jews (19·9%) and Bedouins (27·5%) (P < 0·01). There were no significant gender differences. Seropositivity increased with age in all population groups. For Jews, seropositivity was associated with place of birth and socioeconomic status. A finding of low seroprevalence rate in Bedouins despite their poor living conditions and close contact with livestock is surprising, and might be attributed to the dry and hot climate conditions in their area of residence. In women of reproductive age the seroprevalence was 15·1% in Jews, 25·4% in Bedouins and 72·3% in Arabs (non-Bedouins). Thus, the majority of pregnant women are susceptible to primary infection withT. gondii, and the risk for congenital toxoplasmosis remains high.

2010 ◽  
Vol 139 (4) ◽  
pp. 530-538 ◽  
Author(s):  
A. HOFHUIS ◽  
W. VAN PELT ◽  
Y. T. H. P. VAN DUYNHOVEN ◽  
C. D. M. NIJHUIS ◽  
L. MOLLEMA ◽  
...  

SUMMARYTo estimate the change in the seroprevalence and risk factors for toxoplasmosis in The Netherlands, a study was conducted in the general population in 2006/2007, similarly designed as a previous study in 1995/1996. Testing 5541 sera for IgG antibodies against Toxoplasma gondii showed a marked decrease of the overall seroprevalence to 26·0% [95% confidence interval (CI) 24·0–28·0], compared to 40·5% (95% CI 37·5–43·4) in 1995/1996. In women of reproductive age the seroprevalence decreased from 35·2% (95% CI 32·9–38·6) in 1995/1996 to 18·5% (95% CI 16·2–20·7) in 2006/2007, leaving the majority of pregnant women susceptible to primary infection with T. gondii and their babies to congenital toxoplasmosis. In participants aged ⩾20 years, Toxoplasma seropositivity was associated with living in the Northwest, living in urban areas, low educational level, consumption of raw pork, keeping a cat, and not having occupational contact with clients or patients. For younger participants, risk factors were keeping sheep or cattle, consumption of raw unwashed vegetables and putting sand in the mouth.


2018 ◽  
Vol 117 ◽  
pp. 52-60 ◽  
Author(s):  
Allison N. Kurti ◽  
Ryan Redner ◽  
Janice Y. Bunn ◽  
Katherine Tang ◽  
Tyler Nighbor ◽  
...  

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Bahram Moazzami ◽  
Shahla Chaichian ◽  
Saeed Samie ◽  
Masoumeh Majidi Zolbin ◽  
Fatemeh Jesmi ◽  
...  

Abstract Background In today’s world, coronavirus disease 2019 (COVID-19) is the most critical health problem and research is continued on studying the associated factors. But it is not clear whether endometriosis increases the risk of COVID-19. Methods Women who referred to the gynecology clinic were evaluated and 507 women with endometriosis (case group) were compared with 520 women without endometriosis (control group). COVID-19 infection, symptoms, exposure, hospitalization, isolation, H1N1 infection and vaccination, and past medical history of the participants were recorded and compared between the groups using IBM SPSS Statistics for Windows version 21. Results Comparison between the groups represent COVID-19 infection in 3.2% of the case group and 3% of the control group (P = 0.942). The control group had a higher frequency of asymptomatic infection (95.7% vs. 94.5%; P < 0.001) and fever (1.6% vs. 0%; P = 0.004), while the frequency of rare symptoms was more common in the case group (P < 0.001). The average disease period was 14 days in both groups (P = 0.694). COVID-19 infection was correlated with close contact (r = 0.331; P < 0.001 in the case group and r = 0.244; P < 0.001 in the control group), but not with the history of thyroid disorders, H1N1 vaccination, traveling to high-risk areas, and social isolation (P > 0.05). Conclusion Endometriosis does not increase the susceptibility to COVID-19 infections, but alters the manifestation of the disease. The prevalence of the disease may depend on the interaction between the virus and the individual’s immune system but further studies are required in this regard.


2020 ◽  
Vol 66 (2) ◽  
pp. 162-166
Author(s):  
I.V. Menzhinskaya ◽  
A.G. Melkumyan ◽  
S.V. Pavlovich ◽  
V.D. Chuprynin ◽  
L.V. Vanko ◽  
...  

Endometriosis is a common estrogen-dependent chronic disease in women of reproductive age; it is associated with dysregulation of the immune response, local inflammation, and increased formation of autoantibodies. The aim of the study was to investigate the profile of autoantibodies in women with endometriosis and to evaluate their diagnostic value using new modifications of enzyme immunoassay. In women with endometriosis of stage III-IV (n=39), a wide spectrum of autoantibodies was detected, mainly of class G, including antibodies to endometrial antigens (tropomyosin 3, tropomodulin 3), the enzyme α-enolase, steroid (estradiol, progesterone) and gonadotropic hormones. At the same time, the frequency of detection of IgG antibodies to tropomyosin 3, α-enolase, estradiol and human chorionic gonadotropin and their levels in patients with endometriosis were higher than in healthy women (n=26) (p


2020 ◽  
Author(s):  
Bahram Moazzami ◽  
Shahla Chaichian ◽  
Saeed Samie ◽  
Masoumeh Majidi Zolbin ◽  
Fatemeh Jesmi ◽  
...  

Abstract Background: In today’s world, coronavirus disease 2019 (COVID–19) is the most critical health problem and research is continued on studying the associated factors. But it is not clear whether endometriosis increases the risk of COVID–19.Methods: Women who referred to the gynecology clinic were evaluated and 507 women with endometriosis (case group) were compared with 520 women without endometriosis (control group). COVID–19 infection, symptoms, exposure, hospitalization, isolation, H1N1 infection and vaccination, and past medical history of the participants were recorded and compared between the groups using IBM SPSS Statistics for Windows version 21.Results: Comparison between the groups represent COVID–19 infection in 3.2% of the case group and 3% of the control group (P=.942). The control group had a higher frequency of asymptomatic infection (95.7% vs. 94.5%; P<.001) and fever (1.6% vs. 0%; P=.004), while the frequency of rare symptoms was more common in the case group (P<.001). The average disease period was 14 days in both groups (P=.694). COVID–19 infection was correlated with close contact (r=.331; P<.001 in the case group and r=.244; P<.001 in the control group), but not with the history of thyroid disorders, H1N1 vaccination, traveling to high-risk areas, and social isolation (P>.05).Conclusion: Endometriosis does not increase the susceptibility to COVID–19 infections, but alters the manifestation of the disease. The prevalence of the disease may depend on the interaction between the virus and the individual’s immune system but further studies are required in this regard.


2018 ◽  
Vol 117 ◽  
pp. 61-68 ◽  
Author(s):  
Alexa A. Lopez ◽  
Ryan Redner ◽  
Allison N. Kurti ◽  
Diana R. Keith ◽  
Andrea C. Villanti ◽  
...  

PLoS ONE ◽  
2018 ◽  
Vol 13 (11) ◽  
pp. e0207818 ◽  
Author(s):  
Tyler D. Nighbor ◽  
Nathan J. Doogan ◽  
Megan E. Roberts ◽  
Antonio Cepeda-Benito ◽  
Allison N. Kurti ◽  
...  

2012 ◽  
Vol 141 (10) ◽  
pp. 2192-2195 ◽  
Author(s):  
M. MOSTI ◽  
B. PINTO ◽  
A. GIROMELLA ◽  
S. FABIANI ◽  
R. CRISTOFANI ◽  
...  

SUMMARYThis study aimed to estimate possible changes in seroprevalence of anti-Toxoplasma gondii IgG and IgM antibodies in people living in the area of Massa and Carrara (central Italy), in recent years. Serum samples from over 13 000 individuals were tested for both IgG and IgM anti-Toxoplasma antibodies using an immunoenzymatic method (Access® Toxo IgG, and Access® Toxo IgM II, Beckman Coulter Inc., USA). Our survey showed a decreasing trend of overall seroprevalence of 24·4% [95% confidence interval (CI) 22·62–25·71] in 2010 compared to 31·0% (95% CI 29·29–32·72) in 2007. A positive trend according to age was found, with low positivity observed in younger age groups. For women of reproductive age the prevalence of IgG antibodies was 30·2% (95% CI 28·44–31·96) in 2007 and 23·6% (95% CI 22·05–25·20) in 2010. IgM seroprevalence in women of this age group also progressively decreased from 1·6% to 0·97% during the study period. Our study confirms a decline of toxoplasmosis in Western countries.


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