The role of depression in the insomnia of people with subjective memory impairment, mild cognitive impairment, and dementia in a community sample of elderly individuals in South Korea

2016 ◽  
Vol 29 (4) ◽  
pp. 653-661 ◽  
Author(s):  
Won-Hyoung Kim ◽  
Ji-Hyun Kim ◽  
Byung-Soo Kim ◽  
Sung-Man Chang ◽  
Dong-Woo Lee ◽  
...  
Keyword(s):  
Memory Impairment ◽  
Community Sample ◽  
The Elderly ◽  
Sociodemographic Factors ◽  
Subjective Memory ◽  
Elderly Individuals ◽  
Sleep Complaints ◽  
Subjective Memory Impairment ◽  
Significant Relationships ◽  
The Relationship

ABSTRACTBackground:This study investigates the relationship between insomnia and cognitive dysfunctions including, subjective memory impairment (SMI), mild cognitive impairment (MCI), and dementia, by considering depression in a community sample of elderly individuals.Methods:Data for 1,740 elderly individuals aged 65 years and over were obtained from a nationwide dementia epidemiological study conducted in South Korea. Cognitive functional status was assessed by the Mini-Mental State Examination and the Consortium to Establish a Registry for Alzheimer's Disease Assessment Packet Clinical Assessment Battery. Insomnia was defined as the presence of at least one of the four sleep complaints (difficulty in initiating sleep, difficulty in maintaining sleep, early morning awakening, and non-restorative sleep), accompanied by moderate to severe daytime consequences. Depression was evaluated using the Geriatric Depression Scale.Results:The prevalence of insomnia in the patients with SMI, MCI, and dementia was found to be 23.2%, 19.6%, and 31.0%, respectively. The patients with SMI, MCI, and dementia were significantly more likely to have insomnia and the four sleep complaints than the normal comparison patients. After adjusting for sociodemographic factors, the significant relationships between cognitive dysfunctional status and insomnia remained. However, after adjusting for sociodemographic factors and depression, no significant relationships with any of the sleep complaints or insomnia remained.Conclusion:Insomnia is a very common complaint in the elderly with SMI, MCI, and dementia. Depression might play an important factor in the relationship between insomnia and cognitive dysfunctional status in the elderly.

Hippocampal volume and subjective memory impairment in depressed patients

2004 ◽  
Vol 19 (7) ◽  
pp. 438-440 ◽  
Author(s):  
Armin von Gunten ◽  
Maria A. Ron
Keyword(s):  
Memory Impairment ◽  
Hippocampal Volume ◽  
Subjective Memory ◽  
Subjective Memory Impairment ◽  
Depressed Patients ◽  
The Right ◽  
The Relationship

AbstractThe relationship between severity of subjective memory impairment and volume of the hippocampus/amygdala complex was investigated in non-demented depressed patients and it was found to correlate with decreasing volume in the right hippocampus.

scholarly journals Characteristics of Performance according to Type of Semantic Lexical Task in Normal Elderly and Individuals with Subjective Memory Impairment

2021 ◽  
Vol 17 (3) ◽  
pp. 300-306
Author(s):  
Sangwook Park ◽  
JungWan Kim
Keyword(s):  
Reaction Time ◽  
Memory Impairment ◽  
Low Frequency ◽  
The Elderly ◽  
Semantic Knowledge ◽  
Semantic Association ◽  
Subjective Memory ◽  
Subjective Memory Impairment ◽  
Category Fluency ◽  
Fluency Test

Purpose: For comparison of a semantic knowledge processing of the elderly, particularly the normal individuals and individuals with subjective memory impairment, this study aims to clarify what factors of semantic knowledge task could sensitively discriminate between the two groups by conducting various types of tasks and analyzing the aspects.Methods: High/low frequency category fluency test, concrete/abstract noun word defining test, and semantic association task were performed by 30 normal subjects and 30 subjective memory impaired subjects over 65 years old. Total and each subcategory scores were assessed for the category fluency test and word defining test, and correct response and reaction time were measured for the semantic association task.Results: It was found that there were significant differences between the two groups in the total score of the category fluency task (p < 0.001), low-frequency category score, abstract noun word defining task score (p < 0.05), and reaction time of semantic association task (p < 0.01).Conclusion: The result showed that in case of a target word with lower contact frequency and more abstract concept, the elderly with subjective memory impairment have difficulties in neural-networking activation of semantic knowledge and control of interruption stimulation when approaching a target word, with increased reaction time. This findings demonstrate that a semantic and lexical task has a clinical significance in discriminating a subjective memory impairment group.

The Gospel Oak Study stage IV: the clinical relevance of subjective memory impairment in older people

1995 ◽  
Vol 25 (4) ◽  
pp. 779-786 ◽  
Author(s):  
R. Tobiansky ◽  
R. Blizard ◽  
G. Livingston ◽  
A. Mann
Keyword(s):  
Older People ◽  
Memory Impairment ◽  
Community Sample ◽  
Stage Iv ◽  
Subjective Memory ◽  
Subjective Memory Impairment ◽  
Memory Complaints ◽  
Screening Questions ◽  
Population Screen ◽  
With Memory

SYNOPSISThe prevalence rate of subjective memory impairment (SMI) and its value as a predictor of future depression or dementia was studied in a community sample of elderly residents in one electoral ward using the short-CARE. SMI was found to be common, occurring in 25% of subjects. Subjects with SMI were more likely to be suffering from either dementia or depression than those without the complaint, although 60% of subjects with SMI did not have evidence of either disorder. When followed up over a 2-year period, subjects with SMI were found to be at four-fold greater risk of developing future dementia and two-fold greater risk of developing a depression compared with those without SMI. The SMI scale was not found to be useful as a population screen for dementia or depression, although two of the nine items might have value as screening questions in clinical circumstances to determine those with memory complaints at risk for dementia.

Subjective Memory Impairment. A review of its definitions indicates the need for a comprehensive set of standardised and validated criteria

2008 ◽  
Vol 23 (5) ◽  
pp. 321-330 ◽  
Author(s):  
Khaled Abdulrab ◽  
Reinhard Heun
Keyword(s):  
Memory Impairment ◽  
Predictive Power ◽  
The Elderly ◽  
Subjective Memory ◽  
Standard Definition ◽  
Subjective Memory Impairment ◽  
Literature Searches ◽  
Increased Risk ◽  
Definition Of ◽  
Published Research

AbstractBackgroundSubjective Memory Impairment (SMI) may hold value in the elderly as a predictor of dementia. There is yet to exist any standard definition of SMI for use in research or for clinical practice.ObjectiveThis study aims to identify previous and current definitions of SMI used in published research and to propose a set of criteria that may help increase SMI's predictive power of future cognitive decline.MethodsLiterature searches were conducted across a number of electronic databases including Medline.Results515 citations were identified, 336 papers were obtained, of which 44 were selected for containing definitions for SMI. These definitions varied widely in terms of the types of questions used to determine SMI and additional features pertaining to memory complaints included in the definition.ConclusionThere is no consistency in how SMI is defined. We propose a set of criteria aimed to increase specificity of memory complainers for those at increased risk of dementia. Further research is required to refine and validate the different criteria suggested. An international consent on the necessary criteria by experts in the field might be useful.

scholarly journals The Independent and Joint Effects of Different Childhood Abuse Types on Subjective Prospective and Retrospective Memory Impairment During Pregnancy

2021 ◽  
Vol 12 ◽  
Author(s):  
Xuan Zhang ◽  
Liuliu Wu ◽  
Juan Wang ◽  
Fangxiang Mao ◽  
Jiwei Sun ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Childhood Abuse ◽  
Emotional Abuse ◽  
Memory Impairment ◽  
Linear Regression Analysis ◽  
Retrospective Memory ◽  
Negative Effects ◽  
Subjective Memory ◽  
Subjective Memory Impairment ◽  
The Relationship

Background and Objective: Childhood abuse is considered a risk factor in various health outcomes during pregnancy. However, no study has explored the relationship between childhood abuse and memory impairment during pregnancy. This study is the first to explore the relationship between childhood abuse and subjective memory impairment.Participants, Setting, and Methods: A total of 1,825 pregnant women were recruited from a comprehensive hospital in Shandong province, China, and completed a questionnaire survey. Multivariable linear regression analysis was used to explore the relationship between childhood abuse and subjective prospective and retrospective memory.Results: Pregnant women with high total childhood abuse scores had high prospective and retrospective memory impairment. Among pregnant women reporting only emotional abuse, only physical abuse, or only sexual abuse, women reporting only emotional abuse were found to have high prospective and retrospective memory impairment. Women with all three childhood abuse types also had high prospective and retrospective memory impairment.Conclusion: Women who experienced childhood abuse, especially childhood emotional abuse, had high subjective memory impairment during pregnancy. It is important to ask pregnant women about their experiences of childhood abuse, especially emotional abuse, during early prenatal care, as such abuse is likely to have negative effects on memory during pregnancy.

Risk factors of major depression in the elderly

2005 ◽  
Vol 20 (3) ◽  
pp. 199-204 ◽  
Author(s):  
Reinhard Heun ◽  
Sandra Hein
Keyword(s):  
Risk Factors ◽  
Multivariate Analysis ◽  
Depressive Episode ◽  
Memory Impairment ◽  
Somatoform Disorders ◽  
Significant Risk ◽  
The Elderly ◽  
Subjective Memory ◽  
Subjective Memory Impairment ◽  
Increased Risk

AbstractBackgroundSeveral risk factors of depression have been identified in retrospective as well as some prospective studies in the elderly. Confirmation in independent samples is needed. The present follow-up study prospectively investigated risk factors of depression in an elderly German sample.MethodsOne thousand four hundred and thirty-one subjects from a family study were re-investigated after 4.7 ± 2.5 years. Bivariate and multivariate forward logistic regression analyses were used to identify risk factors of the development of new depression in the elderly.ResultsRisk factors of a new depressive episode in 1408 elderly without current depression were age, female gender, a previous depression, subjective memory impairment, previous anxiety and somatoform disorders. The presence of dementia or mild cognitive impairment were significant risk factors in bivariate, but not multivariate analysis controlling for possible confounding. Risk factors of a first geriatric depressive episode were age, gender and subjective memory impairment; age remained the only significant risk factor in multivariate analysis.ConclusionsThis investigation confirms previous studies from other countries concerning the relevance of risk factors for depression in the elderly. The knowledge of risk factors might help identify subjects at increased risk of depression for early intervention approaches. Elderly with a history of previous depression carry the highest risk.

The Anterior-posterior Functional Connectivity Disconnection in the Elderly with Subjective Memory Impairment and Amnestic Mild Cognitive Impairment

2020 ◽  
Vol 17 (4) ◽  
pp. 373-381
Author(s):  
Wuhai Tao ◽  
Jinping Sun ◽  
Xin Li ◽  
Wen Shao ◽  
Jing Pei ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Functional Connectivity ◽  
Memory Impairment ◽  
Amnestic Mild Cognitive Impairment ◽  
Magnetic Resonance Imaging Scan ◽  
Subjective Memory ◽  
Long Distance ◽  
Whole Brain ◽  
Subjective Memory Impairment

Background: Subjective Memory Impairment (SMI) may tremendously increase the risk of Alzheimer’s Disease (AD). The full understanding of the neuromechanism of SMI will shed light on the early intervention of AD. Methods: In the current study, 23 Healthy Controls (HC), 22 SMI subjects and 24 amnestic Mild Cognitive Impairment (aMCI) subjects underwent the comprehensive neuropsychological assessment and the resting-state functional magnetic resonance imaging scan. The difference in the connectivity of the Default Mode Network (DMN) and Functional Connectivity (FC) from the Region of Interest (ROI) to the whole brain were compared, respectively. Results: The results showed that HC and SMI subjects had significantly higher connectivity in the region of the precuneus area compared to aMCI subjects. However, from this region to the whole brain, SMI and aMCI subjects had significant FC decrease in the right anterior cingulum, left superior frontal and left medial superior frontal gyrus compared to HC. In addition, this FC change was significantly correlated with the cognitive function decline in participants. Conclusion: Our study indicated that SMI subjects had relatively intact DMN connectivity but impaired FC between the anterior and posterior brain. The findings suggest that long-distance FC is more vulnerable than the short ones in the people with SMI.

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