scholarly journals High rates of serum selenium deficiency among HIV- and HCV-infected and uninfected drug users in Buenos Aires, Argentina

2011 ◽  
Vol 15 (3) ◽  
pp. 538-545 ◽  
Author(s):  
Heidi B Sheehan ◽  
Jorge Benetucci ◽  
Estela Muzzio ◽  
Liliana Redini ◽  
Jorge Naveira ◽  
...  
Keyword(s):  
Drug Users ◽  
Buenos Aires ◽  
Selenium Deficiency ◽  
Multivariate Regression Analysis ◽  
Serum Selenium ◽  
Dietary Interventions ◽  
Heavy Alcohol Consumption ◽  
Food Recalls ◽  
Average Serum ◽  
Low Serum

AbstractObjectiveTo describe the prevalence of low serum Se and determine whether HIV, hepatitis C virus (HCV) and/or the types of drugs used are associated with serum Se in a cohort of infected and uninfected drug users.DesignIndependent correlates of low serum Se levels based on data collected from food recalls, physical examinations and clinical questionnaires were identified using multivariate regression analysis.SettingBuenos Aires, ArgentinaSubjectsA total of 205 (twenty-five female and 180 male) former and current drug users.ResultsDrug users had an average serum Se level of 69·8 (sd 32·8) μg/dl, and 82 % were considered deficient (<85 μg/dl). Multivariate analyses found that HIV- and/or HCV-infected individuals had lower mean Se compared with healthy, uninfected drug users (HIV/HCV co-infection: −25·3 μg/l (se 7·6), P = 0·001; HIV alone: −28·9 μg/l (se 6·9), P < 0·001; HCV alone: −19·4 μg/l (se 7·1), P = 0·006). Current and previous drug use was associated with higher serum Se. Cigarette smoking and heavy alcohol consumption were not found to be associated with Se status.ConclusionsLow serum Se levels are highly prevalent among drug users in Buenos Aires, Argentina. Se supplementation and/or dietary interventions may be warranted in drug users who are at high risk for HIV and/or HCV infection.

scholarly journals High rates of serum selenium deficiency among HIV- and HCV-infected and uninfected drug users in Buenos Aires, Argentina – Corrigendum

2011 ◽  
Vol 15 (1) ◽  
pp. 186-186
Author(s):  
Heidi B Sheehan ◽  
Jorge Benetucci ◽  
Estela Muzzio ◽  
Liliana Redini ◽  
Jorge Naveira ◽  
...  
Keyword(s):  
Drug Users ◽  
Buenos Aires ◽  
Selenium Deficiency ◽  
Serum Selenium

scholarly journals Association of Initial Low Serum Selenium Level with Infectious Complications and 30-Day Mortality in Multiple Trauma Patients

Nutrients ◽  
2019 ◽  
Vol 11 (8) ◽  
pp. 1844 ◽  
Author(s):  
Soon Bo Choi ◽  
Yun Tae Jung ◽  
Jae Gil Lee
Keyword(s):  
Multiple Trauma ◽  
Selenium Deficiency ◽  
Infectious Complications ◽  
Selenium Level ◽  
Trauma Patients ◽  
Serum Selenium ◽  
Serum Selenium Levels ◽  
Multiple Trauma Patients ◽  
Serum Selenium Level ◽  
Low Serum

Low serum selenium levels are commonly observed in critically injured multiple trauma patients. This study aimed to identify the association between initial serum selenium levels and in-hospital infectious complications in multiple trauma patients. We retrospectively reviewed multiple trauma patients admitted between January 2015 and November 2017. We selected 135 patients whose serum selenium levels were checked within 48 h of admission. Selenium deficiency was defined as a serum selenium level <70 ng/mL. Survival analyses of selenium deficiency and 30-day mortality were performed. Multivariate logistic regression analysis was performed to identify the association between initial serum selenium level and in-hospital infectious complications. Thirty-day mortality (8.3% vs. 0.0%; p = 0.018) and incidence rates of pneumonia (66.7% vs. 28.3%; p < 0.001) and infectious complications (83.3% vs. 46.5%; p < 0.001) were higher in patients with selenium deficiency than in patients without selenium deficiency. Kaplan–Meier survival cures also showed similar results (log rank test, p = 0.021). Of 135 patients, 76 (56.3%) experienced at least one infectious complication during admission. High injury severity score (ISS, odds ratio (OR) 1.065, 95% confidence interval (CI) 1.024–1.108; p = 0.002) and selenium deficiency (OR 3.995, 95% CI 1.430–11.156; p = 0.008) increased the risk of in-hospital infectious complications in multiple trauma patients. Patients with selenium deficiency showed higher 30-day mortality and higher risks of pneumonia and infectious complications.

Low serum selenium concentration in patients with colonic adenomatous polyps

1993 ◽  
Vol 12 ◽  
pp. 46
Author(s):  
F. Fernández-Bañares ◽  
M. Esteve ◽  
M.D. Mingorance ◽  
A. Abad-Lacruz ◽  
E. Cabré ◽  
...  
Keyword(s):  
Selenium Concentration ◽  
Adenomatous Polyps ◽  
Serum Selenium ◽  
Serum Selenium Concentration ◽  
Low Serum

scholarly journals High Seroprevalence of Bloodborne Viruses among Street‐Recruited Injection Drug Users from Buenos Aires, Argentina

2003 ◽  
Vol 37 (s5) ◽  
pp. S348-52 ◽  
Author(s):  
Mercedes Weissenbacher ◽  
Diana Rossi ◽  
Graciela Radulich ◽  
Sergio Sosa‐Estáni ◽  
Marcelo Vila ◽  
...  
Keyword(s):  
Injection Drug Users ◽  
Drug Users ◽  
Buenos Aires ◽  
Injection Drug ◽  
High Seroprevalence ◽  
Bloodborne Viruses

scholarly journals Low serum selenium in pregnancy is associated with reduced T3 and increased risk of GDM

2021 ◽  
Vol 248 (1) ◽  
pp. 45-57
Author(s):  
Pierre Hofstee ◽  
Janelle James-McAlpine ◽  
Daniel R McKeating ◽  
Jessica J Vanderlelie ◽  
James S M Cuffe ◽  
...  
Keyword(s):  
Thyroid Hormone ◽  
Pregnant Women ◽  
Thyroid Function ◽  
Tertiary Care ◽  
Endocrine Disorders ◽  
Serum Selenium ◽  
Selenium Status ◽  
Increased Risk ◽  
The Relationship ◽  
Low Serum

Thyroid disorders are the most common endocrine disorders affecting women commencing pregnancy. Thyroid hormone metabolism is strongly influenced by selenium status; however, the relationship between serum selenium concentrations and thyroid hormones in euthyroid pregnant women is unknown. This study investigated the relationship between maternal selenium and thyroid hormone status during pregnancy by utilizing data from a retrospective, cross-sectional study (Maternal Outcomes and Nutrition Tool or MONT study) with cohorts from two tertiary care hospitals in South East Queensland, Australia. Pregnant women (n = 206) were recruited at 26–30 weeks gestation and serum selenium concentrations were assessed using inductively coupled plasma mass spectrometry. Thyroid function parameters were measured in serum samples from women with the lowest serum selenium concentrations (51.2 ± 1.2 µg/L), women with mean concentrations representative of the entire cohort (78.8 ± 0.4 µg/L) and women with optimal serum selenium concentrations (106.9 ± 2.3 µg/L). Women with low serum selenium concentrations demonstrated reduced fT3 levels (P < 0.05) and increased TPOAb (P < 0.01). Serum selenium was positively correlated with fT3 (P < 0.05) and negatively correlated with TPOAb (P < 0.001). Serum fT4 and thyroid-stimulating hormone (TSH) were not different between all groups, though the fT4/TSH ratio was increased in the low selenium cohort (P < 0.05). Incidence of pregnancy disorders, most notably gestational diabetes mellitus, was increased within the low serum selenium cohort (P < 0.01). These results suggest selenium status in pregnant women of South East Queensland may not be adequate, with possible implications for atypical thyroid function and undesirable pregnancy outcomes.

scholarly journals The role of selenium and vitamin E in a Transylvanian enzootic equine recurrent rhabdomyolysis syndrome

2021 ◽  
Author(s):  
Csaba Attila Kósa ◽  
Krisztina Nagy ◽  
Ottó Szenci ◽  
Boglárka Baska-Vincze ◽  
Emese Andrásofszky ◽  
...  
Keyword(s):  
Vitamin E ◽  
Serum Vitamin ◽  
Selenium Deficiency ◽  
Selenium Concentration ◽  
Severe Form ◽  
Serum Selenium ◽  
Muscle Enzymes ◽  
Affected Area ◽  
Recurrent Rhabdomyolysis

Abstract A severe form of recurrent exertional rhabdomyolysis occurs enzootically in a well-defined region of Transylvania, Harghita county. At the highest lying two settlements (more than 800 m above sea level), the prevalence of equine rhabdomyolysis is between 17 and 23%, while in the neighbouring villages in the valley it is less than 2%. The objective of our study was to clarify the role of selenium and vitamin E in the high prevalence of rhabdomyolysis in that region. Soil and hay samples were collected from each area to evaluate mineral content. Ten horses from the non-affected and 20 horses from the affected area were tested for serum selenium, vitamin E, glutathione peroxidase (GSH-Px), muscle enzymes, lactate and electrolytes. Hay samples collected from the affected area had lower selenium content. Horses in the affected regions had significantly lower serum selenium (P = 0.006) and GSH-Px levels than animals living in the non-affected regions. A good correlation between erythrocyte GSH-Px and serum selenium concentration could be demonstrated (r = 0.777, P < 0.001). Serum vitamin E levels were low independently of the origin of the horse. Based on our results, selenium deficiency possibly has a role in the Transylvanian enzootic equine recurrent rhabdomyolysis syndrome.

scholarly journals Low serum albumin and the acute phase response predict low serum selenium in HIV-1 infected women

2006 ◽  
Vol 6 (1) ◽  
Author(s):  
Paul K Drain ◽  
Jared M Baeten ◽  
Julie Overbaugh ◽  
Mark H Wener ◽  
Daniel D Bankson ◽  
...  
Keyword(s):  
Serum Albumin ◽  
Acute Phase ◽  
Acute Phase Response ◽  
Phase Response ◽  
Serum Selenium ◽  
Hiv 1 ◽  
Low Serum

Low serum selenium concentration is associated with preeclampsia in pregnant women from Bangladesh

2016 ◽  
Vol 33 ◽  
pp. 21-25 ◽  
Author(s):  
Md. Mahmodul Haque ◽  
Md. Mizanur Rahman Moghal ◽  
Md. Shahid Sarwar ◽  
Shamima Nasrin Anonna ◽  
Mariyam Akter ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Selenium Concentration ◽  
Serum Selenium ◽  
Serum Selenium Concentration ◽  
Low Serum
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