scholarly journals High rates of serum selenium deficiency among HIV- and HCV-infected and uninfected drug users in Buenos Aires, Argentina – Corrigendum

2011 ◽  
Vol 15 (1) ◽  
pp. 186-186
Author(s):  
Heidi B Sheehan ◽  
Jorge Benetucci ◽  
Estela Muzzio ◽  
Liliana Redini ◽  
Jorge Naveira ◽  
...  
Keyword(s):  
Drug Users ◽  
Buenos Aires ◽  
Selenium Deficiency ◽  
Serum Selenium

scholarly journals High rates of serum selenium deficiency among HIV- and HCV-infected and uninfected drug users in Buenos Aires, Argentina

2011 ◽  
Vol 15 (3) ◽  
pp. 538-545 ◽  
Author(s):  
Heidi B Sheehan ◽  
Jorge Benetucci ◽  
Estela Muzzio ◽  
Liliana Redini ◽  
Jorge Naveira ◽  
...  
Keyword(s):  
Drug Users ◽  
Buenos Aires ◽  
Selenium Deficiency ◽  
Multivariate Regression Analysis ◽  
Serum Selenium ◽  
Dietary Interventions ◽  
Heavy Alcohol Consumption ◽  
Food Recalls ◽  
Average Serum ◽  
Low Serum

AbstractObjectiveTo describe the prevalence of low serum Se and determine whether HIV, hepatitis C virus (HCV) and/or the types of drugs used are associated with serum Se in a cohort of infected and uninfected drug users.DesignIndependent correlates of low serum Se levels based on data collected from food recalls, physical examinations and clinical questionnaires were identified using multivariate regression analysis.SettingBuenos Aires, ArgentinaSubjectsA total of 205 (twenty-five female and 180 male) former and current drug users.ResultsDrug users had an average serum Se level of 69·8 (sd 32·8) μg/dl, and 82 % were considered deficient (<85 μg/dl). Multivariate analyses found that HIV- and/or HCV-infected individuals had lower mean Se compared with healthy, uninfected drug users (HIV/HCV co-infection: −25·3 μg/l (se 7·6), P = 0·001; HIV alone: −28·9 μg/l (se 6·9), P < 0·001; HCV alone: −19·4 μg/l (se 7·1), P = 0·006). Current and previous drug use was associated with higher serum Se. Cigarette smoking and heavy alcohol consumption were not found to be associated with Se status.ConclusionsLow serum Se levels are highly prevalent among drug users in Buenos Aires, Argentina. Se supplementation and/or dietary interventions may be warranted in drug users who are at high risk for HIV and/or HCV infection.

scholarly journals High Seroprevalence of Bloodborne Viruses among Street‐Recruited Injection Drug Users from Buenos Aires, Argentina

2003 ◽  
Vol 37 (s5) ◽  
pp. S348-52 ◽  
Author(s):  
Mercedes Weissenbacher ◽  
Diana Rossi ◽  
Graciela Radulich ◽  
Sergio Sosa‐Estáni ◽  
Marcelo Vila ◽  
...  
Keyword(s):  
Injection Drug Users ◽  
Drug Users ◽  
Buenos Aires ◽  
Injection Drug ◽  
High Seroprevalence ◽  
Bloodborne Viruses

scholarly journals The role of selenium and vitamin E in a Transylvanian enzootic equine recurrent rhabdomyolysis syndrome

2021 ◽  
Author(s):  
Csaba Attila Kósa ◽  
Krisztina Nagy ◽  
Ottó Szenci ◽  
Boglárka Baska-Vincze ◽  
Emese Andrásofszky ◽  
...  
Keyword(s):  
Vitamin E ◽  
Serum Vitamin ◽  
Selenium Deficiency ◽  
Selenium Concentration ◽  
Severe Form ◽  
Serum Selenium ◽  
Muscle Enzymes ◽  
Affected Area ◽  
Recurrent Rhabdomyolysis

Abstract A severe form of recurrent exertional rhabdomyolysis occurs enzootically in a well-defined region of Transylvania, Harghita county. At the highest lying two settlements (more than 800 m above sea level), the prevalence of equine rhabdomyolysis is between 17 and 23%, while in the neighbouring villages in the valley it is less than 2%. The objective of our study was to clarify the role of selenium and vitamin E in the high prevalence of rhabdomyolysis in that region. Soil and hay samples were collected from each area to evaluate mineral content. Ten horses from the non-affected and 20 horses from the affected area were tested for serum selenium, vitamin E, glutathione peroxidase (GSH-Px), muscle enzymes, lactate and electrolytes. Hay samples collected from the affected area had lower selenium content. Horses in the affected regions had significantly lower serum selenium (P = 0.006) and GSH-Px levels than animals living in the non-affected regions. A good correlation between erythrocyte GSH-Px and serum selenium concentration could be demonstrated (r = 0.777, P < 0.001). Serum vitamin E levels were low independently of the origin of the horse. Based on our results, selenium deficiency possibly has a role in the Transylvanian enzootic equine recurrent rhabdomyolysis syndrome.

scholarly journals Association of Initial Low Serum Selenium Level with Infectious Complications and 30-Day Mortality in Multiple Trauma Patients

Nutrients ◽  
2019 ◽  
Vol 11 (8) ◽  
pp. 1844 ◽  
Author(s):  
Soon Bo Choi ◽  
Yun Tae Jung ◽  
Jae Gil Lee
Keyword(s):  
Multiple Trauma ◽  
Selenium Deficiency ◽  
Infectious Complications ◽  
Selenium Level ◽  
Trauma Patients ◽  
Serum Selenium ◽  
Serum Selenium Levels ◽  
Multiple Trauma Patients ◽  
Serum Selenium Level ◽  
Low Serum

Low serum selenium levels are commonly observed in critically injured multiple trauma patients. This study aimed to identify the association between initial serum selenium levels and in-hospital infectious complications in multiple trauma patients. We retrospectively reviewed multiple trauma patients admitted between January 2015 and November 2017. We selected 135 patients whose serum selenium levels were checked within 48 h of admission. Selenium deficiency was defined as a serum selenium level <70 ng/mL. Survival analyses of selenium deficiency and 30-day mortality were performed. Multivariate logistic regression analysis was performed to identify the association between initial serum selenium level and in-hospital infectious complications. Thirty-day mortality (8.3% vs. 0.0%; p = 0.018) and incidence rates of pneumonia (66.7% vs. 28.3%; p < 0.001) and infectious complications (83.3% vs. 46.5%; p < 0.001) were higher in patients with selenium deficiency than in patients without selenium deficiency. Kaplan–Meier survival cures also showed similar results (log rank test, p = 0.021). Of 135 patients, 76 (56.3%) experienced at least one infectious complication during admission. High injury severity score (ISS, odds ratio (OR) 1.065, 95% confidence interval (CI) 1.024–1.108; p = 0.002) and selenium deficiency (OR 3.995, 95% CI 1.430–11.156; p = 0.008) increased the risk of in-hospital infectious complications in multiple trauma patients. Patients with selenium deficiency showed higher 30-day mortality and higher risks of pneumonia and infectious complications.

scholarly journals Clinical study of experimentally induced vitamin E and selenium deficiency in Awassi ewes and their newborn lambs

2012 ◽  
Vol 36 (2) ◽  
pp. 158-162
Author(s):  
H. K. Abood
Keyword(s):  
Body Weight ◽  
Clinical Study ◽  
Vitamin E ◽  
Clinical Signs ◽  
Selenium Deficiency ◽  
Serum Selenium ◽  
Deficient Diet ◽  
Sheep Industry ◽  
Experimental Induction ◽  
Deficient Group

Experimental induction of vitamin E and selenium deficiency by deficient diet was carried out on Awassi ewes and their newborn lambs. The clinical signs were characterized by sudden death in 4 lambs out of 14 lambs in deficient group and other lambs showed a variable signs included inability to suckle, arched back, weakness, dullness, emaciation and recumbency. Serum selenium and vitamin E levels of these lambs were 0.01 ppm and 0.34 mg/L respectively. The clinical signs in ewes included loss of body weight and loss of wool, Weakness, dullness and recumbency. Serum selenium and vitamin E levels of these ewes were 0.02 ppm and 0.61mg/L respectively. It was concluded that vitamin E and selenium are essential antioxidants and their deficiency exposes the sheep industry to many serious losses.

scholarly journals INVESTIGATION OF THE SELENIUM STATUS AND ACTIVITY OF THE ANTIOXIDANT SYSTEM IN THE ROMANOV SHEEP IN THE NORTH-WESTERN REGION

2021 ◽  
Vol 248 (4) ◽  
pp. 136-140
Author(s):  
A.A. Kurilova ◽  
◽  
L.Yu. Karpenko ◽  
◽  
Keyword(s):  
Metabolic Diseases ◽  
Selenium Deficiency ◽  
Western Region ◽  
Serum Selenium ◽  
Production Loss ◽  
Selenium Status ◽  
The North ◽  
Antioxidant Function ◽  
Nutritional Element ◽  
North Western

The extension of the characteristics of the cattle ration is widely spread nowadays. One of the most significant nutritional element is selenium. Selenium has antioxidant function because it is a necessary part of the antioxidant enzyme glutathione peroxidase. There is a deficiency of selenium on the large territories of Russian Federation, especially on North-Western region. The selenium deficiency is the reason of different metabolic diseases and stiff lamb disease. All of the aforesaid leads to production loss. In this article it is firstly reported about selenium status, biochemistry characteristics and their variations after treatment selenium –containing drug among Romanov sheep in north-western region. In the course of study was found that selenium concertation in sheep serum was lower than normal. The selenium drug administration was led to an increase of serum selenium concertation

Selenium deficiency as a possible factor in the pathogenesis of myxoedematous endemic cretinism

1987 ◽  
Vol 114 (4) ◽  
pp. 497-502 ◽  
Author(s):  
P. Goyens ◽  
J. Golstein ◽  
B. Nsombola ◽  
H. Vis ◽  
J. E. Dumont
Keyword(s):  
Glutathione Peroxidase ◽  
Oxygen Toxicity ◽  
Selenium Deficiency ◽  
Serum Levels ◽  
Serum Selenium ◽  
Endemic Cretinism ◽  
Plasma Glutathione Peroxidase ◽  
Plasma Glutathione ◽  
Low Selenium

Abstract. Myxoedematous endemic cretinism is prevalent in African goitre endemies. It has been related to a thyroid 'exhaustion' atrophy occurring near birth. It is proposed that this might result from the low resistance of a fragile tissue to enhanced H2O2 generation under intense thyroid stimulation by thyrotropin. In support of this hypothesis, low selenium and glutathione peroxidase serum levels have been found in the African endemic area of the Idjwi Island (Kivu, Zaire). Serum selenium and plasma glutathione peroxidase were lower in the area of high endemicity of goitre and cretinism (Northern part of the Island). However, only the former difference is statistically significant. These data thus suggest a role of oligoelements and oxygen toxicity in the pathogenesis of endemic cretinism.

scholarly journals Age-related Reference Values for Serum Selenium Concentrations in Infants and Children

2002 ◽  
Vol 48 (3) ◽  
pp. 555-560 ◽  
Author(s):  
Ania C Muntau ◽  
Monika Streiter ◽  
Matthias Kappler ◽  
Wulf Röschinger ◽  
Irene Schmid ◽  
...  
Keyword(s):  
Reference Values ◽  
Electrothermal Atomic Absorption Spectrometry ◽  
Selenium Deficiency ◽  
Selenium Supplementation ◽  
Specific Reference ◽  
Serum Selenium ◽  
Healthy Children ◽  
Restricted Diet ◽  
Age Related ◽  
Protein Restricted Diet

Abstract Background: Children are at particular risk for selenium deficiency, which has potentially serious medical implications. Reliable age-specific reference values for serum selenium concentrations in children are sparse, but are essential for the identification of selenium deficiency and decisions regarding selenium supplementation. Methods: Using electrothermal atomic absorption spectrometry, we analyzed serum selenium concentrations from 1010 apparently healthy children (age range, 1 day to 18 years) and from 60 patients on a protein-restricted diet because of inborn errors of metabolism. Reference intervals were defined according to recommended guidelines. Results: Medians for serum selenium concentrations showed a statistically significant age dependency: a decrease from the age &lt;1 month (0.64 μmol/L) to 4 months (0.44 μmol/L); an increase to 0.62 μmol/L in the 4–12 months age group; constant values in children between 1 and 5 years of age (0.90 μmol/L); and an additional slight increase to reach a plateau between 5 and 18 years (0.99 μmol/L). Of 43 children older than 1 year and on a protein-restricted diet, 87% showed serum selenium concentrations below the 2.5 percentile. Conclusions: Because of nutritional changes, serum selenium concentrations are significantly higher in older children than in infants under 1 year of age. The application of age-adjusted reference values may provide more specific criteria for selenium supplementation. Long-term protein restriction in children is reflected by a failure to achieve higher serum selenium concentrations with increasing age.

scholarly journals The HIV/AIDS epidemic and changes in injecting drug use in Buenos Aires, Argentina

2006 ◽  
Vol 22 (4) ◽  
pp. 741-750 ◽  
Author(s):  
Diana Rossi ◽  
María Pía Pawlowicz ◽  
Victoria Rangugni ◽  
Dhan Zunino Singh ◽  
Paula Goltzman ◽  
...  
Keyword(s):  
Drug Use ◽  
Injection Drug Users ◽  
Drug Users ◽  
Buenos Aires ◽  
Injecting Drug Use ◽  
Sex Partners ◽  
Aids Epidemic ◽  
Depth Interviews ◽  
Hiv Aids

This article discusses the changes in injecting drug use from 1998 to 2003 in Buenos Aires, Argentina. The Rapid Situation Assessment and Response methodology was used to obtain the information. Quantitative and qualitative techniques were triangulated: 140 current IDUs and 35 sex partners of injection drug users (IDUs) were surveyed; 17 in-depth interviews with the surveyed IDUs and 2 focus groups were held, as well as ethnographic observations. The way in which risk and care practices among injecting drug users changed and the influence of the HIV/ AIDS epidemic on this process are described. In recent years, the frequency of injection practices and sharing of injecting equipment has decreased, while injecting drug use is a more hidden practice in a context of increasing impact of the disease in the injecting drug use social networks and changes in the price and quality of drugs. Knowledge about these changes helps build harm reduction activities oriented to IDUs in their particular social context.

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