Validation of GATE Monte Carlo code for simulation of proton therapy using National Institute of Standards and Technology library data

2018 ◽  
Vol 18 (1) ◽  
pp. 38-45 ◽  
Author(s):  
Shiva Zarifi ◽  
Hadi Taleshi Ahangari ◽  
Sayyed Bijan Jia ◽  
Mohammad Ali Tajik-Mansoury
Keyword(s):  
Monte Carlo ◽  
Energy Range ◽  
Water Medium ◽  
Monte Carlo Code ◽  
Statistical Uncertainty ◽  
Simulation Code ◽  
Simulation Efficiency ◽  
Optimal Value ◽  
Beam Range ◽  
Range Calculation

AbstractAimTo validate the Geant4 Application for Tomographic Emission (GATE) Monte Carlo simulation code by calculating the proton beam range in the therapeutic energy range.Materials and methodsIn this study, the GATE code which is based on Geant4 was used for simulation. The proton beams in the therapeutic energy range (5–250 MeV) were simulated in a water medium, and then compared with the data from National Institute of Standards and Technology (NIST) in order to investigate the accuracy of different physics list available in the GATE code. In addition, the optimal value of SetCut was assessed.ResultsIn all energy ranges, the QBBC physics had a greater deviation in the ranges relative to the NIST data. With respect to the range calculation accuracy, the QGSP_BIC_EMY and QGSP_BERT_HP_EMY physics were in the range of statistical uncertainty; however, QGSP_BIC_EMY produced better results using the least squares. Based on an investigation into the range calculation precision and simulation efficiency, the optimal SetCut was set at 0·1 mm.FindingsBased on an investigation into the range calculation precision and simulation yield, the QGSP_BIC_EMY physics and the optimal SetCut was recommended to be 0·1 mm.

GATE MODELING OF LATERAL SCATTERING OF PROTON PENCIL BEAMS

2020 ◽  
Vol 189 (1) ◽  
pp. 76-88
Author(s):  
Shiva Zarifi ◽  
Hadi Taleshi Ahangari ◽  
Sayyed Bijan Jia ◽  
Mohammad Ali Tajik-Mansoury ◽  
Milad Najafzadeh
Keyword(s):  
Monte Carlo Simulation ◽  
Monte Carlo ◽  
Energy Range ◽  
Ionization Potential ◽  
Gaussian Function ◽  
Gaussian Model ◽  
Absorbed Dose ◽  
Body Tissue ◽  
Simulation Code ◽  
Optimal Value

Abstract To validate the GATE Monte Carlo simulation code and to investigate the lateral scattering of proton pencil beams in the major body tissue elements in the therapeutic energy range. In this study, GATE Monte Carlo simulation code was used to compute absorbed dose and fluence of protons in a water cubic phantom for the clinical energy range. To apply the suitable physics model for simulation, different physics lists were investigated. The present research also investigated the optimal value of the water ionization potential as a simulation parameter. Thereafter, the lateral beam profile of proton pencil beams were simulated at different energies and depths in body tissue elements. The range results obtained using the QGSP_BIC_EMY physics showed the best compatibility with the NIST database data. Moreover, it was found that the 76 eV is the optimal value for the water ionization potential. In the next step, it was shown that the beam halo can be described by adding a supplementary Gaussian function to the standard single-Gaussian model, which currently is used by treatment planning systems (TPS).

scholarly journals A comprehensive Monte Carlo study to design a novel multi-nanoparticle loaded nanocomposites for augmentation of attenuation coefficient in the energy range of diagnostic X-rays

2021 ◽  
Vol 27 (4) ◽  
pp. 279-289
Author(s):  
Elahe Sayyadi ◽  
Asghar Mesbahi ◽  
Reza Eghdam Zamiri ◽  
Farshad Seyyed Nejad
Keyword(s):  
Monte Carlo ◽  
Energy Range ◽  
Radiation Protection ◽  
Experimental Studies ◽  
Rubber Matrix ◽  
Photon Flux ◽  
Monte Carlo Code ◽  
X Rays ◽  
Wide Range ◽  
Shielding Properties

Abstract Introduction: The present study aimed to investigate the radiation protection properties of silicon-based composites doped with nano-sized Bi2O3, PbO, Sm2O3, Gd2O3, WO3, and IrO2 particles. Radiation shielding properties of Sm2O3 and IrO2 nanoparticles were investigated for the first time in the current study. Material and methods: The MCNPX (2.7.0) Monte Carlo code was utilized to calculate the linear attenuation coefficients of single and multi-nano structured composites over the X-ray energy range of 10–140 keV. Homogenous distribution of spherical nanoparticles with a diameter of 100 nm in a silicon rubber matrix was simulated. The narrow beam geometry was used to calculate the photon flux after attenuation by designed nanocomposites. Results: Based on results obtained for single nanoparticle composites, three combinations of different nano-sized fillers Sm2O3+WO3+Bi2O3, Gd2O3+WO3+Bi2O3, and Sm2O3+WO3+PbO were selected, and their shielding properties were estimated. In the energy range of 20-60 keV Sm2O3 and Gd2O3 nanoparticles, in 70-100 keV energy range WO3 and for photons energy higher than 90 keV, PbO and Bi2O3 nanoparticles showed higher attenuation. Despite its higher density, IrO2 had lower attenuation compared to other nanocomposites. The results showed that the nanocomposite containing Sm2O3, WO3, and Bi2O3 nanoparticles provided better shielding among the studied samples. Conclusions: All studied multi-nanoparticle nanocomposites provided optimum shielding properties and almost 8% higher attenuation relative to single nano-based composites over a wide range of photon energy used in diagnostic radiology. Application of these new composites is recommended in radiation protection. Further experimental studies are suggested to validate our findings.

scholarly journals Towards muon-electron scattering at NNLO

2020 ◽  
Vol 2020 (11) ◽  
Author(s):  
Carlo M. Carloni Calame ◽  
Mauro Chiesa ◽  
Syed Mehedi Hasan ◽  
Guido Montagna ◽  
Oreste Nicrosini ◽  
...  
Keyword(s):  
Monte Carlo ◽  
Electron Scattering ◽  
Photon Radiation ◽  
Monte Carlo Code ◽  
Radiative Corrections ◽  
Small Momentum Transfer ◽  
Simulation Code ◽  
Theoretical Formulation ◽  
Loop Contribution ◽  
The Impact

Abstract The recently proposed MUonE experiment at CERN aims at providing a novel determination of the leading order hadronic contribution to the muon anomalous magnetic moment through the study of elastic muon-electron scattering at relatively small momentum transfer. The anticipated accuracy of the order of 10ppm demands for high-precision predictions, including all the relevant radiative corrections. The theoretical formulation for the fixed-order NNLO photonic radiative corrections is described and the impact of the numerical results obtained with the corresponding Monte Carlo code is discussed for typical event selections of the MUonE experiment. In particular, the gauge-invariant subsets of corrections due to electron radiation as well as to muon radiation are treated exactly. The two-loop contribution due to diagrams where at least two virtual photons connect the electron and muon lines is approximated taking inspiration from the classical Yennie-Frautschi-Suura approach. The calculation and its Monte Carlo implementation pave the way towards the realization of a simulation code incorporating the full set of NNLO corrections matched to multiple photon radiation, that will be ultimately needed for data analysis.

INCOMPLETE FUSION IN THE EXCITATION FUNCTIONS OF 12C + 115In REACTIONS AT 4–7 MeV/NUCLEON

2006 ◽  
Vol 15 (01) ◽  
pp. 237-245 ◽  
Author(s):  
S. MUKHERJEE ◽  
A. SHARMA ◽  
S. SODAYE ◽  
A. GOSWAMI ◽  
B. S. TOMAR
Keyword(s):  
Monte Carlo Simulation ◽  
Monte Carlo ◽  
Energy Range ◽  
Coulomb Barrier ◽  
Incomplete Fusion ◽  
Simulation Code ◽  
Excitation Functions ◽  
Complete And Incomplete Fusion ◽  
Evaporation Residues ◽  
Fusion Products

We measured the excitation functions for nine evaporation residues for the 12C + 115In system in the energy range well beyond the Coulomb barrier. The experimental results are compared with the theoretical values calculated using the Monte Carlo simulation code PACE2. Several complete and incomplete fusion products are observed in the present study. It is observed that a definite amount of incomplete fusion contribution is present, even at the lowest energy. The results clearly show the incomplete fusion contributions in the iodine and antimony products.

scholarly journals Evaluation of Electron Specific Absorbed Fractions in Organs of Digimouse Voxel Phantom Using Monte Carlo Simulation Code FLUKA

2019 ◽  
Vol 9 (2Apr) ◽  
Author(s):  
A Sinha ◽  
N Singh ◽  
B M Dixit ◽  
N K Painuly ◽  
H K Patni ◽  
...  
Keyword(s):  
Monte Carlo ◽  
Electron Energy ◽  
Absorbed Dose ◽  
Radiological Protection ◽  
Monte Carlo Code ◽  
Simulation Code ◽  
Human Organ ◽  
Voxel Phantom ◽  
Publication Number ◽  
Target Organs

Background: For preclinical evaluations of radiopharmaceuticals, most studies are carried out on mice. Values of electron specific absorbed fractions (SAF) have had vital role in the assessment of absorbed dose. In past studies, electron specific absorbed fractions were given for limited source target pairs using older reports of human organ compositions.Objective: Electron specific absorbed fraction values for monoenergetic electrons of energies 15, 50, 100, 500, 1000 and 4000 keV were evaluated for the Digimouse voxel phantom incorporated in Monte Carlo code FLUKA. The organ sources considered in this study were lungs, skeleton, heart, bladder, testis, stomach, spleen, pancreas, liver, kidney, adrenal, eye and brain. The considered target organs were lungs, skeleton, heart, bladder, testis, stomach, spleen, pancreas, liver, kidney, adrenal and brain. Eye and brain were considered as target organs only for eye and brain as source organs. From the latest report (International Commission on Radiological Protection ICRP) publication number 110, organ compositions and densities were adopted.Results: The electron specific absorbed fraction values for self-irradiation decreases with increasing electron energy. The electron specific absorbed fraction values for cross-irradiation are also found to be dependent on the electron energy and the geometries of source and target. Organ masses and electron specific absorbed fraction values are presented in tabular form. Conclusion: The results of this study will be useful in evaluating the absorbed dose to various organs of mice similar in size to the present study. 

INVESTIGATION OF APPLICABILITY OF PURE PROPANE GAS FOR MICRODOSIMETRY AT NEUTRON FIELDS: A MONTE CARLO STUDY

2018 ◽  
Vol 185 (1) ◽  
pp. 74-86 ◽  
Author(s):  
Arghya Chattaraj ◽  
T Palani Selvam ◽  
D Datta
Keyword(s):  
Monte Carlo ◽  
Energy Range ◽  
Neutron Energy ◽  
Proportional Counter ◽  
Monte Carlo Study ◽  
Monte Carlo Code ◽  
Scaling Factors ◽  
Neutron Sources ◽  
Tissue Equivalent ◽  
Tissue Equivalent Proportional Counter

Abstract Applicability of pure propane gas for microdosimetric measurements in neutron fields was investigated using the FLUKA Monte Carlo code. Monoenergetic neutrons in the energy range 1 keV−20 MeV and the ISO-neutron sources such as 241Am-Be, 241Am-B, 252Cf and 252Cf + D2O were considered in the present study. The tissue-equivalent proportional counter (TEPC) simulated in the study was LET-1/2 (by Far West Technology) with site sizes 1, 2 and 8 μm. The study demonstrates that for a given site size, the TEPC filled with tissue-equivalent propane and pure propane gases produce similar microdosimetric distributions when the density of pure propane gas is lowered appropriately. For the ISO-neutron sources, the density of propane gas requires scaling by a factor 0.85. For the monoenergetic neutrons, depending upon the neutron energy, the values of scaling factors are in the range of 0.58–0.93.

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