scholarly journals Higher Anxiety Is Associated with Lower Cardiovascular Autonomic Function in Female Twins

2020 ◽  
Vol 23 (3) ◽  
pp. 156-164
Author(s):  
Zeynep Nas ◽  
Harriëtte Riese ◽  
Arie M. van Roon ◽  
Frühling V. Rijsdijk

AbstractAnxiety symptoms co-occur with cardiovascular health problems, with increasing evidence suggesting the role of autonomic dysfunction. Yet, there is limited behavior genetic research on underlying mechanisms. In this twin study, we investigated the phenotypic, genetic and environmental associations between a latent anxiety factor and three cardiovascular autonomic function factors: interbeat interval (IBI, time between heart beats), heart rate variability (HRV, overall fluctuation of heart-beat intervals) and baroreflex sensitivity (BRS, efficiency in regulating blood pressure [BP]). Multivariate twin models were fit using data of female twins (N = 250) of the Twin Interdisciplinary Neuroticism Study (TWINS). A significant negative association was identified between latent anxiety and BRS factors (r = −.24, 95% CI [−.40, −.07]). Findings suggest that this relationship was mostly explained by correlated shared environmental influences, and there was no evidence for pleiotropic genetic or unique environmental effects. We also identified negative relationships between anxiety symptoms and HRV (r = −.17, 95% CI [−.34, .00]) and IBI factors (r = −.13, 95% CI [−.29, .04]), though these associations did not reach statistical significance. Findings implicate that higher anxiety scores are associated with decreased efficiency in short-term BP regulation, providing support for autonomic dysfunction with anxiety symptomatology. The baroreflex system may be a key mechanism underlying the anxiety–cardiovascular health relationship.


2014 ◽  
Vol 5 (3) ◽  
pp. 91-94 ◽  
Author(s):  
M.I.Glad Mohesh ◽  
K Ratchagan ◽  
A Sundaramurthy

Background: WHO (2010) reported the rise in the number of smokeless tobacco users in India. Dipping tobacco is a form of smokeless tobacco being used in these region in various trade names. Nicotine in smoking tobacco is found to alter the cardiovascular autonomic functions. As the expected cardiovascular mortality due to tobacco use across the globe is very high, here we studied the effect of dipping tobacco on cardiovascular autonomic function using the short term heart rate variability (HRV) analysis. Methods: Five minutes Lead II ECG at rest is aquired from male dipping tobacco moderate users (n=30) and age matched controls (n=30). Frequency and time domain parameters were derived and analysed using the Kubios HRV analysis software. Blood pressure changes were also compared. Unpaired ‘t’ test was done using SPSS 17.0 and statistical significance was set at p<0.05. Results: Significant changes in certain parameters indicated that there is a developing set back in the sympathetic control over the heart (LF, 383.8+115.8, 952.8+131.1, p<0.01) and also an established increase in diastolic blood pressure (73.1+2.8, 65.48+1.5, p<0.01). Conclusion: Dipping tobacco a form of smokeless tobacco is equally harmful like any smoked tobacco in altering the cardiovascular autonomic function. Thereby the increase in smokeless tobacco users in India or any country is going to add up more to the mortality rate due to tobacco related diseases in near future as estimated by WHO. An immediate measure to stop the production, sale and use of these smokeless tobacco products could curb this menace. Asian Journal of Medical Science, Volume-5(3) 2014: 91-94 http://dx.doi.org/10.3126/ajms.v5i3.9588



Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 554-P
Author(s):  
LYNN ANG ◽  
KELLEY M. KIDWELL ◽  
JACOB REISS ◽  
BRENDAN R. DILLON ◽  
KARA R. MIZOKAMI-STOUT ◽  
...  


Author(s):  
Camilla Rocchi ◽  
Rocco Cerroni ◽  
Matteo Conti ◽  
Benedetta Lauretti ◽  
Alessandro Stefani ◽  
...  


2021 ◽  
Author(s):  
◽  
V. J. Martínez Hernández

Exercise induces parasympathetic withdrawal and sympathetic activation. Heart rate variability (HRV) is a noninvasive tool for the assessment of cardiac autonomic function. Physical training can improve cardiovascular health through an increase in HRV. In this study, two physical trainings were conducted, one with moderate intensity (MT) and the second one with higher intensity (IT), for 10 weeks. A test protocol which consisted of 3 maneuvers: control, exercise, and recovery was performed each week of training to follow up the HRV changes in 18 sedentary volunteers aged 20.3±2 years. The RR intervals were analyzed by indexes of traditional Poincaré plot (SPP) and segmented Poincaré plot (SEPP). The results showed an increase in column 7 probabilities in week 10 with respect to week 4 during control stage for both trainings. Regarding, trainings differences, row 9 probability decreases in MT training suggesting a higher cardiac vagal activity in this training.



Obesity ◽  
2007 ◽  
Vol 15 (2) ◽  
pp. 364-369 ◽  
Author(s):  
Raelene E. Maser ◽  
M. James Lenhard ◽  
Isaias Irgau ◽  
Gail M. Wynn


PLoS ONE ◽  
2016 ◽  
Vol 11 (8) ◽  
pp. e0161604 ◽  
Author(s):  
Nelli Perkiömäki ◽  
Juha Auvinen ◽  
Mikko P. Tulppo ◽  
Arto J. Hautala ◽  
Juha Perkiömäki ◽  
...  


2018 ◽  
Vol 43 (2) ◽  
pp. 136-146 ◽  
Author(s):  
Marcus Mund ◽  
Franz J. Neyer

Individuals feel lonely when they perceive a discrepancy between their desired and their actually experienced quantity and quality of social relationships. Prior research has demonstrated the importance of loneliness for various health-related aspects. In the present article, we extend the existing literature on loneliness by investigating its role for predicting personality traits and their development from late adolescence to early midlife. Using data from a representative German sample ( N = 12,402) sampling individuals from three different birth cohorts, we found loneliness to predict the levels of all Big Five traits except openness five years later. The effects of loneliness on the development of neuroticism and extraversion reached statistical significance but were only marginal in terms of effect size. Furthermore, we found that a self-regulatory focus geared to the prevention of negative events mediated the effects of loneliness on later levels of the Big Five.



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