Design and Optimization of a Corona Discharge Ion Source for Supercritical Fluid Chromatography Time-of-Flight Mass Spectrometry

1996 ◽  
Vol 68 (11) ◽  
pp. 1924-1932 ◽  
Author(s):  
Iulia M. Lazar ◽  
Milton L. Lee ◽  
Edgar D. Lee
Keyword(s):  
Mass Spectrometry ◽  
Corona Discharge ◽  
Supercritical Fluid ◽  
Supercritical Fluid Chromatography ◽  
Time Of Flight ◽  
Ion Source ◽  
Design And Optimization ◽  
Flight Mass Spectrometry

Rapid profiling of triacylglycerols for identifying authenticity of edible oils using supercritical fluid chromatography-quadruple time-of-flight mass spectrometry combined with chemometric tools

2016 ◽  
Vol 8 (21) ◽  
pp. 4226-4238 ◽  
Author(s):  
Anqi Tu ◽  
Zhenxia Du ◽  
Shuping Qu
Keyword(s):  
Mass Spectrometry ◽  
Rapid Method ◽  
Supercritical Fluid ◽  
Supercritical Fluid Chromatography ◽  
Edible Oils ◽  
Time Of Flight ◽  
Flight Mass Spectrometry ◽  
Chemometric Tools ◽  
Tof Ms

A rapid method was developed for identifying the authenticity of edible oils using SFC-Q-TOF-MS combined with PCA.

scholarly journals A Rapid and Sensitive Method for the Simultaneous Determination of Multipolar Compounds in Plant Tea by Supercritical Fluid Chromatography Coupled to Ion Mobility Quadrupole Time-of-Flight Mass Spectrometry

Foods ◽  
2022 ◽  
Vol 11 (1) ◽  
pp. 111
Author(s):  
Zi-Xuan Yue ◽  
Jun Cao
Keyword(s):  
Mass Spectrometry ◽  
Supercritical Fluid ◽  
Supercritical Fluid Chromatography ◽  
Ion Mobility ◽  
Solid Phase ◽  
Time Of Flight ◽  
Solution Temperature ◽  
Flight Mass Spectrometry ◽  
Target Analytes ◽  
Collisional Cross Section

In this study, matrix solid phase dispersion (MSPD) microextraction combined with supercritical fluid chromatography-ion mobility quadrupole time-of-flight mass spectrometry (SFC/IM-QTOF-MS) was used to analyze the multipolar compounds in plant tea. The parameters of stationary phase, mobile phase, make-up solution, temperature, and back pressure were optimized. The target analytes were gradient eluted in 8 min by supercritical CO2 on a Zorbax RX-SIL column. Collisional Cross Section (CCS) values for single and multiple fields were measured. A series of validation studies were carried out under the optimal conditions, and the linear relationship and reproducibility were good. The limits of detection were 1.4 (Scoparone (1))~70 (Naringenin (4)) ng/mL, and the limits of quantification were 4.7 (Scoparone (1))~241 (Naringenin (4)) ng/mL. The recoveries of most compounds ranged from 60.7% to 127%. As a consequence, the proposed method was used for the separation and quantitative analysis of active ingredients in caulis dendrobii.

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