Dynamic Alteration in the Vaginal Secretory Proteome across the Early and Mid-Trimesters of Pregnancy

2021 ◽  
Vol 20 (2) ◽  
pp. 1190-1205
Author(s):  
Bhoj Kumar ◽  
Amit Kumar Dey ◽  
Sandhini Saha ◽  
Abhishek Kumar Singh ◽  
Pallavi Kshetrapal ◽  
...  
Keyword(s):  
Dynamic Alteration

Dynamic alteration of internal carotid artery related to granuloma in a case of Tolosa–Hunt syndrome

2021 ◽  
Author(s):  
Takafumi Wada ◽  
Atsushi Shima ◽  
Akira Kuzuya ◽  
Takakuni Maki ◽  
Hirofumi Yamashita ◽  
...  
Keyword(s):  
Carotid Artery ◽  
Internal Carotid Artery ◽  
Internal Carotid ◽  
Hunt Syndrome ◽  
Dynamic Alteration

scholarly journals Dynamic alteration in the gut microbiota and metabolome during the pregnancy

2021 ◽  
Author(s):  
Peifeng Xie ◽  
Chengjun Hu ◽  
Qinghua He ◽  
Qian Zhu ◽  
Xiangfeng Kong
Keyword(s):  
Gut Microbiota ◽  
Metabolic Pathways ◽  
Late Pregnancy ◽  
Metabolite Profile ◽  
Microbiota Composition ◽  
Glutamate Metabolism ◽  
Fat Percentage ◽  
Rrna Sequencing ◽  
Dynamic Alteration ◽  
Gut Microbiota Composition

Abstract Background Gut microbiota and their metabolites were associated with obesity. Our previous study showed that maternal body fat percentage increased from days 45 to 110 of gestation in a Huanjiang mini-pig model. Thus, 16S rRNA sequencing and metabonomic techniques were used to investigate the changes of maternal gut microbiota composition and microbial metabolite profile from days 45 to 110 of gestation. Results The abundances of Clostridium_sensu_stricto_1, Romboutsia, Turicibacter, and Streptococcus in jejunum contents were higher in day 110 than those in day 45 or 75 of gestation. In ileum, the abundance of Streptococcus was the highest (P < 0.05) at day 110 of gestation, as well as the metabolism function of jejunal and ileal microbiota. The ileal butyrate and acetate concentrations were the highest at day 45 and day 110 of gestation, respectively. In colon, the concentrations of cadaverine and spermine were the highest (P < 0.05) at days 45 and 110 of gestation, respectively. Metabonomic analysis demonstrated that metabolic pathways including glutamine and glutamate metabolism, phenylalanine, tyrosine and tryptophan biosynthesis, and alanine, aspartate, and glutamate metabolism changed during gestation. Conclusions Microbiota composition and metabolites changed dramatically from the early to the late pregnancy, which might be associated with the maternal fat accumulation.

Dynamic Alteration of Neutrophil-to-Lymphocyte Ratio over Treatment Trajectory is Associated with Survival in Esophageal Adenocarcinoma

2020 ◽  
Vol 27 (11) ◽  
pp. 4413-4419 ◽  
Author(s):  
Y. Al Lawati ◽  
J. Cools-Lartigue ◽  
J. L. Ramirez-GarciaLuna ◽  
J. C. Molina-Franjola ◽  
D. Pham ◽  
...  
Keyword(s):  
Esophageal Adenocarcinoma ◽  
Neutrophil To Lymphocyte Ratio ◽  
Lymphocyte Ratio ◽  
Dynamic Alteration

scholarly journals Cytosolic T3-binding protein modulates dynamic alteration of T3-mediated gene expression in cells

2014 ◽  
Vol 61 (6) ◽  
pp. 561-570 ◽  
Author(s):  
Keiko Takeshige ◽  
Takashi Sekido ◽  
Jun-ichirou Kitahara ◽  
Yousuke Ohkubo ◽  
Dai Hiwatashi ◽  
...  
Keyword(s):  
Gene Expression ◽  
Binding Protein ◽  
Dynamic Alteration ◽  
In Cells

Artificial scotoma-induced perceptual distortions are orientation dependent and short lived

2004 ◽  
Vol 21 (1) ◽  
pp. 79-87 ◽  
Author(s):  
CHRIS TAILBY ◽  
ANDREW METHA
Keyword(s):  
Visual Cortex ◽  
Receptive Field ◽  
Test Stimulus ◽  
Primary Visual Cortex ◽  
Retinal Area ◽  
One Dimensional ◽  
Cortical Areas ◽  
Perceptual Distortions ◽  
Orientation Specificity ◽  
Dynamic Alteration

Conditioning human observers with an “artificial scotoma”—a small retinal area deprived of patterned stimulation within a larger area of dynamically textured noise—results in contractions and expansions of perceived space that are thought to reflect receptive-field changes among cells in the primary visual cortex (Kapadia et al., 1994). Here we show that one-dimensional counter-phase flickering grating patterns are also potent stimuli for producing artificial scotomata capable of altering three-element bisection ability analogous to those results reported earlier. Moreover, we found that the magnitude of the induced spatial distortions depends critically on the relative orientations of peri-scotomatous and test-stimulus spatial contrast. In addition, the perceptual distortions are found to be relatively short lived, decaying within 660 ms. The results support the hypothesis that artificial scotoma-induced perceptual distortions are generated by dynamic alteration of connection efficacy within a network linking cortical areas of similar orientation specificity, consistent with established anatomical and physiological results.

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