Application of Comparative Lipidomics to Elucidate Postprandial Metabolic Excursions Following Dairy Milk Ingestion in Individuals with Prediabetes

Author(s):  
Li Chen ◽  
Shiqi Zhang ◽  
Xiaowei Sun ◽  
Joshua D. McDonald ◽  
Richard S. Bruno ◽  
...  
Keyword(s):  
2016 ◽  
Vol 116 (2) ◽  
pp. 204-210 ◽  
Author(s):  
Billie K. Alba ◽  
Anna E. Stanhewicz ◽  
W. Larry Kenney ◽  
Lacy M. Alexander

AbstractIn epidemiological studies, chronic dairy milk consumption is associated with improved vascular health and reduced age-related increases in blood pressure. Although milk protein supplementation augments conduit artery flow-mediated dilation, whether or not acute dairy milk intake may improve microvascular function remains unclear. We hypothesised that dairy milk would increase direct measurement of endothelial nitric oxide (NO)-dependent cutaneous vasodilation in response to local skin heating. Eleven men and women (61 (sem2) years) ingested two or four servings (473 and 946 ml) of 1 % dairy milk or a rice beverage on each of 4 separate study days. In a subset of five subjects, an additional protocol was completed after 473 ml of water ingestion. Once a stable blood flow occurred, 15 mm-NG-nitro-l-arginine methyl ester was perfused (intradermal microdialysis) to quantify NO-dependent vasodilation. Red-blood-cell flux (RBF) was measured by laser-Doppler flowmetry, and cutaneous vascular conductance (CVC=RBF/mean arterial pressure) was calculated and normalised to maximum (%CVCmax; 28 mm-sodium nitroprusside). Full expression of cutaneous vasodilation was not different among dairy milk, rice beverage and water, and there was no effect of serving size on the total vasodilatory response. Contrary to our hypothesis, NO-dependent vasodilation was lower for dairy milk than rice beverage (D: 49 (sem5), R: 55 (sem5) %CVCmax;P<0·01). Acute dairy milk ingestion does not augment NO-dependent vasodilation in the cutaneous microcirculation compared with a rice beverage control.


2010 ◽  
Vol 13 (3) ◽  
pp. 650-656 ◽  
Author(s):  
Kristen M. Beavers ◽  
Monica C. Serra ◽  
Daniel P. Beavers ◽  
Geoffrey M. Hudson ◽  
Darryn S. Willoughby

2020 ◽  
Vol 26 (1) ◽  
Author(s):  
Nabil Nabil Moohialdin ◽  
Ahmad Shamsodini ◽  
Steven K. Wilson ◽  
Osama Abdeljaleel ◽  
Ibrahim Alnadhari ◽  
...  

Abstract Background Infection after the penile prosthesis can be devastating to both the patient and surgeon with various complications and consequences. After introduction of antibiotic-coated implants, the rate of infection has dramatically decreased, but still we see uncommon organisms causing infection. We present a first case report of penile prosthesis infection by brucellosis due to raw milk ingestion. To our knowledge, this is the first reported case of brucellosis penile prosthesis infection. Case presentation We present a first case report of penile prosthesis infection by brucellosis due to raw milk ingestion. A 75-year-old, diabetic male patient presented with penile prosthesis infection 5 months post-penile exchange surgery due to mechanical malfunctioning of 2-piece penile prosthesis which was inserted 11 years ago. The initial treatment with broad spectrum antibiotics did not subside the infection. After diagnosis of brucellosis, the antibiotic was changed to anti-brucellosis (Rifampicin + Tetracycline). The patient improved dramatically and was discharged home with smooth follow-up course. Conclusion Brucellosis can cause infection of penile prosthesis and can be treated with anti-brucellosis antibiotics without necessitating surgical intervention and removal of prosthesis.


2014 ◽  
Vol 32 (5) ◽  
pp. 528-542 ◽  
Author(s):  
Xiang You ◽  
Zihao Zhou ◽  
Zhenkai Liao ◽  
Liming Che ◽  
Xiao Dong Chen ◽  
...  

1997 ◽  
Vol 127 (9) ◽  
pp. 1737-1743 ◽  
Author(s):  
Yasuko Motohashi ◽  
Akiko Fukushima ◽  
Takashi Kondo ◽  
Keiko Sakuma

2020 ◽  
Vol 2 (2) ◽  
pp. 58-65
Author(s):  
Jaji Jaji ◽  
◽  
Antarini Idriasari ◽  
M Zainal Fikri

The low coverage of breastfeeding is a threat to the growth and development of children. Some of the things that hinder exclusive breastfeeding include the low level of knowledge of mothers and families about the benefits of breastfeeding, and how to breastfeed properly. In addition, the lack of lactation counseling services and support from health workers, socio-cultural factors, the incessant marketing of formula milk, and factors of working mothers. Some things that can facilitate breastfeeding for working mothers are support from the office environment, support from superiors, coworkers, flexible work schedules, rest periods, positive work colleagues 'attitudes towards breastfeeding, working mothers' attitudes. While some things that can hinder breastfeeding are psychological stress caused by tight work time and discomfort at the time of breastfeeding. Lack of time and location of breastfeeding rooms is also recognized as one of the obstacles in breastfeeding during working hours. The counseling and assistance activities of exclusive breastfeeding are a real form of triad prevention that must be carried out by health workers, especially nurses at the community Health centers. Expressing milk is one of the solutions to keep breastfeeding at work. 5 facilities that can be provided by the workplace to keep breastfeeding, namely: a breast milk pump, a room for milking or a room for breastfeeding, rest periods for milking or for breastfeeding, there is a refrigerator for storing milk and there is support from the workplace. Mothers are committed to giving exclusive breastfeeding to their children, and for workplace institutions to provide opportunities for mothers who have children aged 0-6 months, continue to give their milk by relaxing time for the management of dairy milk.


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