scholarly journals Nanoscale Magnetization and Current Imaging Using Time-Resolved Scanning-Probe Magnetothermal Microscopy

Nano Letters ◽  
2021 ◽  
Author(s):  
Chi Zhang ◽  
Jason M. Bartell ◽  
Jonathan C. Karsch ◽  
Isaiah Gray ◽  
Gregory D. Fuchs
Keyword(s):  
Scanning Probe ◽  
Time Resolved

Nanolocal time-resolved optical study using scanning probe microscope

1999 ◽  
Author(s):  
Yurii E. Lozovik ◽  
A. V. Klyuchnik ◽  
S. P. Merkulova
Keyword(s):  
Scanning Probe Microscope ◽  
Scanning Probe ◽  
Optical Study ◽  
Time Resolved ◽  
Probe Microscope

Investigation of Protein/Lipid Interactions via Scanning Probe Acceleration Microscopy: Theory and Experiment

2012 ◽  
Author(s):  
Justin Legleiter ◽  
Kathleen A. Burke ◽  
Elizabeth A. Yates
Keyword(s):  
Lipid Membrane ◽  
Neurodegenerative Disorder ◽  
Scanning Probe ◽  
Force Curve ◽  
Time Resolved ◽  
Lipid Interactions ◽  
Tapping Mode Afm ◽  
Afm Probe ◽  
Theory And Experiment ◽  
Polyq Domain

There is great interest in the application of proximal probe techniques to simultaneously image and measure mechancial properties of surfaces with nanoscale spatial resolution. There have been several innovations in generating time-resolved force interaction between the tip and surface while acquiring a tapping mode AFM image. These tip/sample forces contain information regarding mechanical properties of surfaces in an analogous fashion to a force curve experiment. Here, we demonstrate, via simulation, that the maximum and minimum tapping forces change with respect to the Young’s modulus and adhesiveness of a surface, but the roughness of the surfaces has no effect on the tapping forces. Using these changes in tapping forces, we determine the mechanical changes of a lipid membrane after exposure to a huntingtin exon1 (htt exon1) protein with an expanded polyglutamine (polyQ) domain. Expanded polyQ domains in htt is associated with Huntington’s disease, a genetic neurodegenerative disorder. The htt exon1 protein caused regions of increased surface roughness to appear in the lipid membrane, and these areas were associated with decreased elasticity and adhesion to the AFM probe.

scholarly journals Time-Resolved Electrical Scanning Probe Microscopy of Layered Perovskites Reveals Spatial Variations in Photoinduced Ionic and Electronic Carrier Motion

ACS Nano ◽  
2019 ◽  
Vol 13 (3) ◽  
pp. 2812-2821 ◽  
Author(s):  
Rajiv Giridharagopal ◽  
Jake T. Precht ◽  
Sarthak Jariwala ◽  
Liam Collins ◽  
Stephen Jesse ◽  
...  
Keyword(s):  
Scanning Probe Microscopy ◽  
Spatial Variations ◽  
Scanning Probe ◽  
Time Resolved ◽  
Probe Microscopy ◽  
Layered Perovskites

Near-Field Second Harmonic Microscopy of Thin Ferroelectric Films

1999 ◽  
Vol 596 ◽  
Author(s):  
I. I. Smolyaninov ◽  
H. Y. Liang ◽  
C. H. Lee ◽  
C. C. Davis ◽  
L. D. Rotter ◽  
...  
Keyword(s):  
Second Harmonic ◽  
Near Field ◽  
Laser System ◽  
Optical Resolution ◽  
Optical Probe ◽  
Ferroelectric Materials ◽  
Scanning Probe ◽  
Fast Time ◽  
Regenerative Amplifier ◽  
Time Resolved

AbstractNear-field second harmonic microscopy is ideally suited for studies of local nonlinearity and poling of ferroelectric materials at the microscopic level. Its main advantages in comparison with other scanning probe techniques are the possibility of fast time-resolved measurements, and substantially smaller perturbation of the sample under investigation caused by the optical probe. We report second harmonic imaging of the surface of thin BaTiO3 films obtained in a near-field microscopy setup using a Ti:sapphire laser system consisting of an oscillator and a regenerative amplifier operating at 810 nm. Optical resolution on the order of 80 nm has been achieved.

scholarly journals The new FAST module: A portable and transparent add-on module for time-resolved investigations with commercial scanning probe microscopes

2019 ◽  
Vol 205 ◽  
pp. 49-56 ◽  
Author(s):  
Carlo Dri ◽  
Mirco Panighel ◽  
Daniel Tiemann ◽  
Laerte L. Patera ◽  
Giulia Troiano ◽  
...  
Keyword(s):  
Scanning Probe ◽  
Time Resolved

Correlation of Atomic Force Microscopy Tapping Forces to Mechanical Properties of Lipid Membranes

2012 ◽  
Author(s):  
Nicole Shamitko-Klingensmith ◽  
Kelley M. Wambaugh ◽  
Kathleen A. Burke ◽  
George J. Magnone ◽  
Justin Legleiter
Keyword(s):  
Mechanical Properties ◽  
Atomic Force Microscopy ◽  
Lipid Membranes ◽  
Scanning Probe ◽  
Second Derivative ◽  
Time Resolved ◽  
Cantilever Deflection ◽  
Force Microscopy ◽  
Atomic Force ◽  
Mode Atomic Force Microscopy

There is considerable interest in measuring, with nanoscale spatial resolution, the physical properties of lipid membranes because of their role in the physiology of living systems. Due to its ability to nondestructively image surfaces in solution, tapping mode atomic force microscopy (TMAFM) has proven to be a useful technique for imaging lipid membranes. However, further information concerning the mechanical properties of surfaces is contained within the time-resolved tip/sample force interactions. The tapping forces can be recovered by taking the second derivative of the cantilever deflection signal and scaling by the effective mass of the cantilever; this technique is referred to as scanning probe acceleration microscopy. Herein, we describe how the maximum and minimum tapping forces change with surface mechanical properties. Furthermore, we demonstrate how these changes can be used to measure mechanical changes in lipid membranes containing cholesterol.

Microtubule nucleation sequence studied by time-resolved x-ray scattering and electron microscopy

1983 ◽  
Vol 41 ◽  
pp. 766-767
Author(s):  
Eva-Maria Mandelkow ◽  
Eckhard Mandelkow ◽  
Joan Bordas
Keyword(s):  
Electron Microscopy ◽  
Dynamic Equilibrium ◽  
Time Resolved ◽  
X Ray ◽  
Additional Information ◽  
X Ray Scattering ◽  
Low Concentrations ◽  
Microtubule Growth ◽  
Ray Patterns ◽  
Ray Scattering

When a solution of microtubule protein is changed from non-polymerising to polymerising conditions (e.g. by temperature jump or mixing with GTP) there is a series of structural transitions preceding microtubule growth. These have been detected by time-resolved X-ray scattering using synchrotron radiation, and they may be classified into pre-nucleation and nucleation events. X-ray patterns are good indicators for the average behavior of the particles in solution, but they are difficult to interpret unless additional information on their structure is available. We therefore studied the assembly process by electron microscopy under conditions approaching those of the X-ray experiment. There are two difficulties in the EM approach: One is that the particles important for assembly are usually small and not very regular and therefore tend to be overlooked. Secondly EM specimens require low concentrations which favor disassembly of the particles one wants to observe since there is a dynamic equilibrium between polymers and subunits.

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