IMPROVING THE EFFICIENCY OF THE CONTACT FORCE METHOD OF THE ATOMIC FORCE SPECTROSCOPY

Предложена методика, оптимизирующая метод контактной силовой спектроскопии. С помощью макроязыка, интегрированного в программное обеспечение NOVA установки сканирующего зондового микроскопа Solver P47, был разработан алгоритм, позволяющий анализировать силовые кривые, не покидая его основного интерфейса. Апробация метода выполнена на образцах синтезированного полимера, поскольку одним из важнейших механических свойств, определяющим их спектр областей применения, является упругость. В работе получены локальные значения модуля Юнга на поверхности полимера методом контактной силовой спектроскопии с применением скрипта YUNG, разработанного с помощью макроязыка, интегрированного в программу управления сканирующего зондового микроскопа. Показано, что применение скрипта YUNG позволяет оптимизировать метод контактной силовой спектроскопии по поиску показателя степени γ, выбору модели для расчета силы взаимодействия для дальнейшего определения локального модуля Юнга. We propose a technique that optimizing the method of contact force spectroscopy. With the help of a macro language integrated into the NOVA software of the Solver P47 scanning probe microscope, an algorithm was developed that allows analyzing force curves without leaving its main interface. The approbation of the method was done on samples of synthesized polymer, since one of the most important mechanical properties determining their range of applications is elasticity. In this paper, local values of the Young's modulus on the polymer surface are obtained by the method of contact force spectroscopy using the YUNG script developed using a macro language integrated into the control program of a scanning probe microscope. It is shown that the use of the YUNG script makes it possible to optimize the method of contact force spectroscopy by searching for the exponent γ, choosing a model for calculating the interaction force for further determination of the local Young modulus.

METHOD OF OBTAINING THE SPECTRAL CHARACTERISTICS OF THE SCANNING PROBE MICROSCOPE

The article discusses methods and algorithms for digital processing and filtering when carrying out nano-measurements using a scanning probe microscope. The paper discusses frequency methods for improving images, in particular, the use of the Fourier transforms with various filtering methods to improve the quality of the resulting image. Stable computational algorithms have been developed for transforming discrete signals based on the Fourier transform. Methods for the interpretation of the numerical results of the discrete Fourier transform in such packages as Matlab, MathCad, Matematica are presented. It is proposed to use a window transform, developed based on the Fourier transform, which makes it possible to single out the informative features of the signal and to reduce the influence of the destabilizing factors that arise when processing signals from a scanning gold microscope in real conditions.

Atomi c-force microscopy of viruses and bacteria

The article is devoted to the study of viruses and bacteria using a scanning probe microscope in atomic force mode, in particular, to the features of sample preparation, interpretation of the data obtained, and image processing.

Drag force of polyethyleneglycol in flows of polymer solutions measured by a scanning probe microscope

The drag force of polyethyleneglycol thiol (mPEG-SH) attached to a cantilever probe in the flows of glycerol and polyethyleneglycol (PEG) solutions was measured. The effects of the molecular weights of...