Light-Stimulated Carbon Dot Hydrogel: Targeting and Clearing Infectious Bacteria In Vivo

Author(s):  
Chang Heon Lee ◽  
Seuk Young Song ◽  
You Jung Chung ◽  
Eun Kyoung Choi ◽  
Jinhyeong Jang ◽  
...  
Keyword(s):  
2018 ◽  
Vol 42 (18) ◽  
pp. 15311-15314 ◽  
Author(s):  
Xiao Juan Lin ◽  
Xiao Qing Fan ◽  
Sai Jin Xiao ◽  
Yan He ◽  
Wen Jing Qi ◽  
...  

A new type of carbon dot (CD) is proposed, which has great potential to be an excellent fluorescent probe for bioimaging in vivo.


The Analyst ◽  
2019 ◽  
Vol 144 (22) ◽  
pp. 6609-6616 ◽  
Author(s):  
Yan Huang ◽  
Na He ◽  
Qi Kang ◽  
Dazhong Shen ◽  
Xiaoyan Wang ◽  
...  

The fluorescent nanoprobe CD-DB complexation with iron ions was used to determine the fluctuation of ascorbic acid induced by hypoxia in living cells, zebrafish and mice.


RSC Advances ◽  
2015 ◽  
Vol 5 (57) ◽  
pp. 46158-46162 ◽  
Author(s):  
Changhui Fu ◽  
Li Qiang ◽  
Qinghua Liang ◽  
Xue Chen ◽  
Linlin Li ◽  
...  

Carbon dots embedded in silica nanorattle (CDs@SN) nanocomposites with high luminescence are synthesized and exhibit brighter fluorescence in vitro and in vivo than CDs alone.


RSC Advances ◽  
2021 ◽  
Vol 11 (46) ◽  
pp. 28809-28817
Author(s):  
Zhuoling Zhong ◽  
Xingying Li ◽  
Shuyao Liu ◽  
Chuanwei Zhang ◽  
Xiaoping Xu ◽  
...  

Carbon dots (CDS) have been proved to be a type of ideal biological imaging probe.


Biomaterials ◽  
2015 ◽  
Vol 51 ◽  
pp. 290-302 ◽  
Author(s):  
Philippe Pierrat ◽  
Rongrong Wang ◽  
Dimitri Kereselidze ◽  
Marie Lux ◽  
Pascal Didier ◽  
...  

2012 ◽  
Vol 124 (29) ◽  
pp. 7297-7301 ◽  
Author(s):  
Anwei Zhu ◽  
Qiang Qu ◽  
Xiangling Shao ◽  
Biao Kong ◽  
Yang Tian

2019 ◽  
Vol 2 (3) ◽  
pp. 11-23 ◽  
Author(s):  
Muktha H ◽  
Sharath R ◽  
Nagaraju Kottam ◽  
Srinath S ◽  
Randhir Y

Treating post-surgical wound is one of the major challenges in the field of medical Science due to the several disadvantages posed by the antibiotics. The antimicrobial and Wound healing activity of metal based nanoparticles were well known, but the effects of carbon dot nanoparticles (C-Dots) are less explored. In the present study a wet chemical method for the synthesis of C-Dots from sucrose, glucose and fructose was developed and they were characterized by UV-Visible, Fluorescent spectroscopic techniques and the pharmaceutical applications such as antibacterial and the wound healing activities were evaluated. The study revealed that the C-Dots synthesized from Sucrose (SCD) and Glucose (GCD) showed potent antibacterial activity against both positive and negative bacterial strains at 12.5µl/ml (0.1 ± 0.003) and Fructose (FCD) at 50 µl/ml (0.1 ± 0.01) compared to the vehicle Control (0.61 ± 0.06). The wound healing of SCD (367.8 ± 15.2) was observed better than the Control (280.8 ± 10.72) and FCD (326.8 ± 9.41). GCD (166.8 ± 10.83) skin tissues indicated best healing as compared to FCD (135.8 ± 8.29), SCD (157.3 ± 16.97) and Control (135.8 ± 8.29). The results suggest that C-Dots applied topically possess wound healing activity and have potential applications as a bacteriostatic agent.


Author(s):  
S. Phyllis Steamer ◽  
Rosemarie L. Devine

The importance of radiation damage to the skin and its vasculature was recognized by the early radiologists. In more recent studies, vascular effects were shown to involve the endothelium as well as the surrounding connective tissue. Microvascular changes in the mouse pinna were studied in vivo and recorded photographically over a period of 12-18 months. Radiation treatment at 110 days of age was total body exposure to either 240 rad fission neutrons or 855 rad 60Co gamma rays. After in vivo observations in control and irradiated mice, animals were sacrificed for examination of changes in vascular fine structure. Vessels were selected from regions of specific interest that had been identified on photomicrographs. Prominent ultrastructural changes can be attributed to aging as well as to radiation treatment. Of principal concern were determinations of ultrastructural changes associated with venous dilatations, segmental arterial stenosis and tortuosities of both veins and arteries, effects that had been identified on the basis of light microscopic observations. Tortuosities and irregularly dilated vein segments were related to both aging and radiation changes but arterial stenosis was observed only in irradiated animals.


Author(s):  
E. J. Kollar

The differentiation and maintenance of many specialized epithelial structures are dependent on the underlying connective tissue stroma and on an intact basal lamina. These requirements are especially stringent in the development and maintenance of the skin and oral mucosa. The keratinization patterns of thin or thick cornified layers as well as the appearance of specialized functional derivatives such as hair and teeth can be correlated with the specific source of stroma which supports these differentiated expressions.


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