Aqueous Protein–Polymer Bioconjugation via Photoinduced RAFT Polymerization Using High Loading Heterogeneous Catalyst

2021 ◽  
Author(s):  
Ya Huang ◽  
Xue Li ◽  
Yu Chi Zhang ◽  
Zhiwei Shi ◽  
Lun Zeng ◽  
...  
Keyword(s):  
Heterogeneous Catalyst ◽  
Raft Polymerization ◽  
High Loading ◽  
Protein Polymer

Visible light induced fast synthesis of protein–polymer conjugates: controllable polymerization and protein activity

2014 ◽  
Vol 50 (49) ◽  
pp. 6506-6508 ◽  
Author(s):  
Xin Li ◽  
Lei Wang ◽  
Gaojian Chen ◽  
David M. Haddleton ◽  
Hong Chen
Keyword(s):  
Visible Light ◽  
Ambient Temperature ◽  
Raft Polymerization ◽  
Protein Activity ◽  
Polymer Conjugates ◽  
Protein Polymer ◽  
Novel Method ◽  
Fast Synthesis

Visible light induced fast and controllable RAFT polymerization from protein as a novel method for preparing protein–polymer conjugates at ambient temperature.

Transiently responsive protein–polymer conjugates via a ‘grafting-from’ RAFT approach for intracellular co-delivery of proteins and immune-modulators

2015 ◽  
Vol 51 (73) ◽  
pp. 13972-13975 ◽  
Author(s):  
N. Vanparijs ◽  
R. De Coen ◽  
D. Laplace ◽  
B. Louage ◽  
S. Maji ◽  
...  
Keyword(s):  
Raft Polymerization ◽  
Immune Modulators ◽  
Polymer Conjugates ◽  
Protein Polymer ◽  
Grafting From ◽  
Response To Temperature

‘Grafting-from’ RAFT polymerization is used to synthesize protein–polymer conjugates that change from the soluble to the aggregated state in response to temperature, but become fully soluble by acid triggered hydrolysis.

scholarly journals Fabrication of low-fouling, high-loading polymeric surfaces through pH-controlled RAFT

RSC Advances ◽  
2020 ◽  
Vol 10 (34) ◽  
pp. 20302-20312
Author(s):  
Alexander H. Jesmer ◽  
Vincent Huynh ◽  
Ryan G. Wylie
Keyword(s):  
Chain Transfer ◽  
Raft Polymerization ◽  
High Loading ◽  
One Pot ◽  
Polymeric Surfaces ◽  
One Pot Synthesis ◽  
Reversible Addition ◽  
Ph Controlled

pH-Controlled surface-reversible addition–fragmentation chain-transfer (S-RAFT) polymerization yields a one-pot synthesis for bimodal polymeric surfaces for improved capture agent immobilization.

The microtubule associated protein (MAP) tau forms a new class of triple-stranded left-hand helical fibrous protein polymer

1992 ◽  
Vol 50 (1) ◽  
pp. 540-541
Author(s):  
G. C. Ruben ◽  
K. Iqbal ◽  
I. Grundke-Iqbal ◽  
H. Wisniewski ◽  
T. L. Ciardelli ◽  
...  
Keyword(s):  
Axial Ratio ◽  
Normal Structure ◽  
Paired Helical Filaments ◽  
Left Hand ◽  
New Class ◽  
Protein Polymer ◽  
Fibrous Protein ◽  
Protein Map ◽  
Neurotransmitter Transport ◽  
Alzheimer Neurofibrillary Tangles

In neurons, the microtubule associated protein, tau, is found in the axons. Tau stabilizes the microtubules required for neurotransmitter transport to the axonal terminal. Since tau has been found in both Alzheimer neurofibrillary tangles (NFT) and in paired helical filaments (PHF), the study of tau's normal structure had to preceed TEM studies of NFT and PHF. The structure of tau was first studied by ultracentrifugation. This work suggested that it was a rod shaped molecule with an axial ratio of 20:1. More recently, paraciystals of phosphorylated and nonphosphoiylated tau have been reported. Phosphorylated tau was 90-95 nm in length and 3-6 nm in diameter where as nonphosphorylated tau was 69-75 nm in length. A shorter length of 30 nm was reported for undamaged tau indicating that it is an extremely flexible molecule. Tau was also studied in relation to microtubules, and its length was found to be 56.1±14.1 nm.

Synthesis of carbonate esters by carboxymethylation using NaAlO2 as a highly active heterogeneous catalyst

2018 ◽  
Author(s):  
Sreerangappa Ramesh ◽  
Kiran Indukuri ◽  
Olivier Riant ◽  
Damien Debecker
Keyword(s):  
Heterogeneous Catalyst ◽  
Dimethyl Carbonate ◽  
Sodium Aluminate ◽  
High Yield ◽  
Solid Catalyst ◽  
Highly Active ◽  
Aromatic Alcohols ◽  
Green Conditions ◽  
Mixed Carbonate

<p>Sodium aluminate is presented as a highly active heterogeneous catalyst able to convert a range of alcohols into the corresponding mixed carbonate esters, in high yield and under green conditions. The reaction is carried out using dimethyl carbonate both as a reactant and solvent, at 90°C. Allylic, aliphatic and aromatic alcohols are converted in good yields. The solid catalyst is shown to be truly heterogeneous, resistant to leaching, and recyclable. </p>

The Synthesis and Application of Functionalized Mesoporous Silica SBA-15 as Heterogeneous Catalyst in Organic Synthesis

2020 ◽  
Vol 24 ◽  
Author(s):  
Ghodsi Mohammadi Ziarani ◽  
Shima Roshankar ◽  
Fatemeh Mohajer ◽  
Alireza Badiei
Keyword(s):  
Mesoporous Silica ◽  
Heterogeneous Catalyst ◽  
Organic Synthesis ◽  
Lewis Acid ◽  
Heterogeneous Catalysts ◽  
Organic Transformations ◽  
Functionalized Mesoporous Silica ◽  
Silica Nanomaterials ◽  
Wide Range ◽  
Target Molecules

Abstract:: Mesoporous silica nanomaterials provide an extraordinary advantage for making new and superior heterogeneous catalysts because of their surface silanol groups. The functionalized mesoporous SBA-15, such as acidic, basic, BrÖnsted, lewis acid, and chiral catalysts, are used for a wide range of organic synthesis. The importance of the chiral ligands, which were immobilized on the SBA-15, was mentioned in this review to achieve chiral products as valuable target molecules. Herein, their synthesis and application in different organic transformations are reviewed from 2016 till date 2020.

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