Sub-Micrometer Magnetic Nanocomposites: Insights into the Effect of Magnetic Nanoparticles Interactions on the Optimization of SAR and MRI Performance

2016 ◽  
Vol 8 (39) ◽  
pp. 25777-25787 ◽  
Author(s):  
Renato Grillo ◽  
Juan Gallo ◽  
Daniel G. Stroppa ◽  
Enrique Carbó-Argibay ◽  
Renata Lima ◽  
...  
2019 ◽  
Vol 73 (1) ◽  
pp. 25-35
Author(s):  
Bojana Markovic ◽  
Vojislav Spasojevic ◽  
Aleksandra Dapcevic ◽  
Zorica Vukovic ◽  
Vladimir Pavlovic ◽  
...  

Magnetic and non-magnetic macroporous crosslinked copolymers of glycidyl methacrylate and trimethylolpropane trimethacrylate were prepared by suspension copolymerization and functionalized with diethylenetriamine. The samples were characterized by mercury porosimetry, scanning electron microscopy with energy-dispersive X-ray spectroscopy (SEM-EDS), Fourier transform infrared spectroscopy analysis (FTIR-ATR), thermogravimetric analysis (TGA), X-ray diffractometry (XRD), atomic force microscopy (AFM), transmission electron microscopy (TEM) and SQUID magnetometry. The FTIR-ATR analysis of synthesized magnetic nanocomposites confirmed the presence of magnetite and successful amino- functionalization. Non-functionalized and amino-functionalized nanocomposites exhibited superparamagnetic behavior at 300 K, with a saturation magnetization of 5.0 emu/g and 2.9 emu/g, respectively. TEM analysis of the magnetic nanocomposite has shown that magnetic nanoparticles were homogeneously dispersed in the polymer matrix. It was demonstrated that incorporation of magnetic nanoparticles enhanced the thermal stability of the magnetic nanocomposite in comparison to the initial non-magnetic macroporous copolymer.


2012 ◽  
Vol 10 (1) ◽  
Author(s):  
Abolfazl Akbarzadeh ◽  
Mohammad Samiei ◽  
Sang Woo Joo ◽  
Maryam Anzaby ◽  
Younes Hanifehpour ◽  
...  

Abstract Background The aim of present study was to develop the novel methods for chemical and physical modification of superparamagnetic iron oxide nanoparticles (SPIONs) with polymers via covalent bonding entrapment. These modified SPIONs were used for encapsulation of anticancer drug doxorubicin. Method At first approach silane–grafted magnetic nanoparticles was prepared and used as a template for polymerization of the N-isopropylacrylamide (NIPAAm) and methacrylic acid (MAA) via radical polymerization. This temperature/pH-sensitive copolymer was used for preparation of DOX–loaded magnetic nanocomposites. At second approach Vinyltriethoxysilane-grafted magnetic nanoparticles were used as a template to polymerize PNIPAAm-MAA in 1, 4 dioxan and methylene-bis-acrylamide (BIS) was used as a cross-linking agent. Chemical composition and magnetic properties of Dox–loaded magnetic hydrogel nanocomposites were analyzed by FT-IR, XRD, and VSM. Results The results demonstrate the feasibility of drug encapsulation of the magnetic nanoparticles with NIPAAm–MAA copolymer via covalent bonding. The key factors for the successful prepardtion of magnetic nanocomposites were the structure of copolymer (linear or cross-linked), concentration of copolymer and concentration of drug. The influence of pH and temperature on the release profile of doxorubicin was examined. The in vitro cytotoxicity test (MTT assay) of both magnetic DOx–loaded nanoparticles was examined. The in vitro tests showed that these systems are no toxicity and are biocompatible. Conclusion IC50 of DOx–loaded Fe3O4 nanoparticles on A549 lung cancer cell line showed that systems could be useful in treatment of lung cancer.


RSC Advances ◽  
2019 ◽  
Vol 9 (35) ◽  
pp. 20087-20099 ◽  
Author(s):  
Pedram Nasehi ◽  
Boshra Mahmoudi ◽  
Seyed Foad Abbaspour ◽  
Mojtaba Saei Moghaddam

In this study, magnetic nanocomposites (UIO-66-MnFe2O4-TiO2) were synthesized based on the metal–organic framework.


2017 ◽  
Vol 502 ◽  
pp. 201-209 ◽  
Author(s):  
Eugenio Redolfi Riva ◽  
Isabel Pastoriza-Santos ◽  
Aidin Lak ◽  
Teresa Pellegrino ◽  
Jorge Pérez-Juste ◽  
...  

2017 ◽  
Vol 100 (1) ◽  
pp. 198-205 ◽  
Author(s):  
Alireza Feizbakhsh ◽  
Shokooh Ehteshami

Abstract In this study, a polythiophene/chitosan polymer and electrospinning polymer nanofibers as modifiercompounds were used, and magnetic nanocomposites as a novel adsorbent were proposed, for the preconcentration of some triazines, includingatrazine, ametryn, and terbutryn, in aqueous samples before GC.The synthesized magnetic nanoparticles, magnetic polymer nanofibers, and polythiophene magnetic nanocomposite were characterizedby scanning electron microscopy. The separation of the target analytes fromthe aqueous solutioncontaining the triazines and different magnetic nanocomposites were simply achieved by applying an external magnetic field. The extraction efficiency of magnetic polyamide nanofiberswas enhanced as compared with other modified magnetic nanoparticles. The main factors affecting the extraction efficiency, including desorption conditions, nanocomposite component ratio, electrospinningtime, sorbent amount, extraction time, ionic strength, and sample pH, were optimized. The developed method proved to be convenient and offers sufficient sensitivity and good reproducibility.Under optimized conditions, the method's LOD (S/N = 3) and LOQ (S/N = 10) were 1–5 and 15ng L−1, respectively; good linearity was obtained within the range of 15–2000 ng L−1 for triazines, with correlation coefficients >0.9997. The RSDat the concentration level of 100 ng L−1 was 9–14% (n = 3). Furthermore, the method was successfully applied to the determination of triazines in realsamples, in which relative recoveriesof 98–103% were obtained. Compared with other methods, the current method is characterized by its ease, fast separation, and low detection limits.


2018 ◽  
Vol 20 ◽  
pp. 149-172 ◽  
Author(s):  
Swati Sharma ◽  
Ambika Verma ◽  
Ashok Kumar ◽  
Hesam Kamyab

Magnetic nanocomposites are multi-component, nanosized magnetic materials, to generate the response to an external stimulus (i.e., outer inert or alternative magnetic field). The novel nanocomposites is a combination of excess of various materials such as liquid crystals, silica, gels, renewable polymers, carbon along with different magnetic particles. They have immense applications in the field of medical diagnosis and therapy, catalysis and separation. These nanocarriers are mainly classified into nanotubes, nanosheets, spherical nanoparticles, nanofibres, highly porous nanocomposites. The porous nanostructures provides a better surface for the entrapment or covalent binding of enzymes, proteins, biomolecules and drugs but the major challenge is to design and synthesize a desired structure with suitable surface properties and biocompatibility. Extensive attempts have been made to manipulate the mesoporous materials and its combination with other structure in order to synthesize a matrix with appropriate pore size, large surface area to volume ratio. “Bottom-up” and “Bottom-down” chemical-based synthesis methods have been widely employed to prepare magnetic nanoparticles. Magnetic nanocomposites are synthesized from magnetic nanoparticles and biopolymers by using sol-gel technique, chemical precipitation methods and NanogenTM, a microwave plasma method. In this chapter, we described the advances and developments in the formation/synthesis of magnetic nanocomposites. This chapter will review the characteristics, properties and applications of the magnetic nanocomposites.


2020 ◽  
Vol 6 (4) ◽  
pp. 49
Author(s):  
Joseph Govan

Water resources are of extreme importance for both human society and the environment. However, human activity has increasingly resulted in the contamination of these resources with a wide range of materials that can prevent their use. Nanomaterials provide a possible means to reduce this contamination, but their removal from water after use may be difficult. The addition of a magnetic character to nanomaterials makes their retrieval after use much easier. The following review comprises a short survey of the most recent reports in this field. It comprises five sections, an introduction into the theme, reports on single magnetic nanoparticles, magnetic nanocomposites containing two of more nanomaterials, magnetic nanocomposites containing material of a biologic origin and finally, observations about the reported research with a view to future developments. This review should provide a snapshot of developments in what is a vibrant and fast-moving area of research.


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