Dual-Therapeutics-Loaded Mesoporous Silica Nanoparticles Applied for Breast Tumor Therapy

2019 ◽  
Vol 11 (50) ◽  
pp. 46497-46503 ◽  
Author(s):  
Xiang Li ◽  
Gao He ◽  
Hui Jin ◽  
Jing Tao ◽  
Xinping Li ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Breast Tumor ◽  
Mesoporous Silica Nanoparticles ◽  
Tumor Therapy

Redox-Responsive Nanocarrier Based on Heparin End-Capped Mesoporous Silica Nanoparticles for Targeted Tumor Therapy in Vitro and in Vivo

Langmuir ◽  
2014 ◽  
Vol 30 (26) ◽  
pp. 7867-7877 ◽  
Author(s):  
Liangliang Dai ◽  
Jinghua Li ◽  
Beilu Zhang ◽  
Junjie Liu ◽  
Zhong Luo ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Tumor Therapy ◽  
Redox Responsive

Recent Developments in Mesoporous Silica Nanoparticles for Tumor Theranostic Applications

2021 ◽  
Vol 27 ◽  
Author(s):  
Xuerui Wang ◽  
Mengyuan Zheng ◽  
Faizal Raza ◽  
Yuhao Liu ◽  
Yiqi Wei ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Tumor Therapy ◽  
Drug Carriers ◽  
Synthetic Methods ◽  
Medicine Research ◽  
Recent Developments ◽  
Theranostic Applications ◽  
Clinical Transformation

: Due to the advantages of adjustable pore size, easy surface modification, high biocompatibility, and so on, mesoporous silica nanoparticles (MSNs) have attracted lots of attention. And they are widely used in the fields of biology and medicine research, mostly focusing on drug and gene delivery and bioimaging. This review introduces several commonly used synthetic methods of MSNs and the latest progress of MSNs in tumor therapy and diagnosis, mainly including the study about modified MSNs as drug carriers and the application of MSNs in bioimaging. The deficiencies of MSNs’ application and prospects for its future clinical transformation are also discussed.

Enzyme responsive mesoporous silica nanoparticles for targeted tumor therapy in vitro and in vivo

Nanoscale ◽  
2015 ◽  
Vol 7 (8) ◽  
pp. 3614-3626 ◽  
Author(s):  
Junjie Liu ◽  
Beilu Zhang ◽  
Zhong Luo ◽  
Xingwei Ding ◽  
Jinghua Li ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Tumor Therapy

Reversibly-regulated drug release using poly(tannic acid) fabricated nanocarriers for reduced secondary side effects in tumor therapy

2020 ◽  
Vol 5 (6) ◽  
pp. 986-998
Author(s):  
Chao Chen ◽  
Tonghao Ma ◽  
Wen Tang ◽  
Xiaoli Wang ◽  
Yibing Wang ◽  
...  
Keyword(s):  
Side Effects ◽  
Drug Release ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Tannic Acid ◽  
Mesoporous Silica Nanoparticles ◽  
Tumor Therapy ◽  
Ph Responsive ◽  
Normal Tissues ◽  
Secondary Side

This article introduced a reversibly pH-responsive and targeting nanocarrier based on mesoporous silica nanoparticles which could be utilized to reduce the “secondary” side effects on normal tissues.

scholarly journals Cetyltrimethylammonium chloride-loaded mesoporous silica nanoparticles as a mitochondrion-targeting agent for tumor therapy

RSC Advances ◽  
2020 ◽  
Vol 10 (29) ◽  
pp. 17050-17057
Author(s):  
Menghuan Tang ◽  
Peng Zhang ◽  
Jiahui Liu ◽  
Yijuan Long ◽  
Yuan Cheng ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Cancer Cells ◽  
Mesoporous Silica Nanoparticles ◽  
Tumor Therapy ◽  
Cetyltrimethylammonium Chloride

CTAC@MSNs-HSA lead to the dysfunction of mitochondria, resulting in the necrosis and apoptosis of cancer cells.

Gas-generating mesoporous silica nanoparticles with rapid localized drug release for enhanced chemophotothermal tumor therapy

2020 ◽  
Vol 8 (23) ◽  
pp. 6754-6763
Author(s):  
Zhiming Zhang ◽  
Li Zhang ◽  
Chenlu Huang ◽  
Qing Guo ◽  
Yueyue Zuo ◽  
...  
Keyword(s):  
Drug Release ◽  
Combination Therapy ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Tumor Therapy ◽  
Promising Strategy

Chemophotothermal combination therapy has emerged as a novel and promising strategy to treat cancer.

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