Ring-Opening Polymerization of N-Carboxyanhydride-Induced Self-Assembly for Fabricating Biodegradable Polymer Vesicles

2019 ◽  
Vol 8 (10) ◽  
pp. 1216-1221 ◽  
Author(s):  
Jinhui Jiang ◽  
Xinyue Zhang ◽  
Zhen Fan ◽  
Jianzhong Du
2008 ◽  
Vol 85 (2) ◽  
pp. 258 ◽  
Author(s):  
Jennifer L. Robert ◽  
Katherine B. Aubrecht

2021 ◽  
Author(s):  
Mathieu J.-L. Tschan ◽  
Régis M. Gauvin ◽  
Christophe M. Thomas

In this review, we describe recent developments in biodegradable polymer synthesis with a focus on the use of discrete complexes and organocatalysts as active initiators for the stereocontrolled ring-opening polymerization of cyclic esters.


2021 ◽  
Author(s):  
Qianqian Shi ◽  
Yibing Chen ◽  
Junjiao Yang ◽  
Jing Yang

Reported here is the first polyester-based bioactive nanoparticles accessed via ring-opening polymerization-induced self-assembly (ROPISA) of salicylic acid o-carboxyanhydride (SAOCA) monomers. Superfast ROPISA of SAOCA was completed in 30 seconds to form worm-like morphology.


2020 ◽  
Vol 04 ◽  
Author(s):  
Manu Singhai ◽  
Sankha Bhattacharya

Abstract:: Polysarcosine (psar) is a non-ionic hydrophilic polypeptoid with numerous biologically relevant properties. Polysarcosine is poly (n-methylated glycine) and has been reported first by wesley and co-workers in the 1920s. Polysarcosine was first synthesized via ring-opening polymerization (rop) of sarcosine n-carboxyanhydride, using high-vacuum techniques. Overall, findings highlight the potential of poly(sarcosine) as an alternative corona-forming polymer to poly (ethylene glycol)-based analogues of (polymerization-induced self-assembly) pisa assemblies for use in various pharmaceutical and biomedical applications. Numerous studies suggested that such polypeptoids hold enormous potential for many biomedical applications, including protein delivery, colloidal stabilization, and nanomedicine.


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