Correction of the cDNA-derived protein sequence of prostatic spermine binding protein: pivotal role of tandem mass spectrometry in sequence analysis

Biochemistry ◽  
1988 ◽  
Vol 27 (12) ◽  
pp. 4214-4221 ◽  
Author(s):  
Robert J. Anderegg ◽  
Steven A. Carr ◽  
I. Yih Huang ◽  
Richard A. Hiipakka ◽  
Chawnshang Chang ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Sequence Analysis ◽  
Tandem Mass Spectrometry ◽  
Protein Sequence ◽  
Binding Protein ◽  
Pivotal Role ◽  
Tandem Mass

scholarly journals Tandem Mass Spectrometry for Peptide and Protein Sequence Analysis

BioTechniques ◽  
2005 ◽  
Vol 38 (4) ◽  
pp. 519-523 ◽  
Author(s):  
Joshua J. Coon ◽  
John E.P. Syka ◽  
Jeffrey Shabanowitz ◽  
Donald F. Hunt
Keyword(s):  
Mass Spectrometry ◽  
Sequence Analysis ◽  
Tandem Mass Spectrometry ◽  
Protein Sequence ◽  
Tandem Mass ◽  
Protein Sequence Analysis

The pivotal role of tandem mass spectrometry in structural determinations of Nod factors produced by Rhizobia

2002 ◽  
Vol 219 (3) ◽  
pp. 703-716 ◽  
Author(s):  
Jean Claude Promé ◽  
Myriam Ferro ◽  
Frederic Debellé ◽  
Danielle Promé ◽  
Hari B Krisnan
Keyword(s):  
Mass Spectrometry ◽  
Tandem Mass Spectrometry ◽  
Pivotal Role ◽  
Tandem Mass ◽  
Nod Factors

Amino Acid Sequence Analysis of Human S100A7 (Psoriasin) by Tandem Mass Spectrometry

1995 ◽  
Vol 217 (1) ◽  
pp. 257-263 ◽  
Author(s):  
D.M. Burgisser ◽  
G. Siegenthaler ◽  
T. Kuster ◽  
U. Hellman ◽  
P. Hunziker ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Amino Acid ◽  
Sequence Analysis ◽  
Amino Acid Sequence ◽  
Tandem Mass Spectrometry ◽  
Tandem Mass ◽  
Amino Acid Sequence Analysis

scholarly journals Steroid Hormone Analysis by Tandem Mass Spectrometry

2009 ◽  
Vol 55 (6) ◽  
pp. 1061-1066 ◽  
Author(s):  
Steven J Soldin ◽  
Offie P Soldin
Keyword(s):  
Mass Spectrometry ◽  
Tandem Mass Spectrometry ◽  
High Performance ◽  
Tandem Mass ◽  
Mass Spectrometers ◽  
Liquid Chromatography Tandem Mass ◽  
Steroid Profiles ◽  
Diagnostic Capabilities ◽  
New Applications

Abstract Background: New high-performance liquid chromatography/tandem mass spectrometry (LC-MS/MS) methods are among the most successful approaches to improve specificity problems inherent in many immunoassays. Content: We emphasize problems with immunoassays for the measurement of steroids and review the emerging role of LC-MS/MS in the measurement of clinically relevant steroids. The latest generation of tandem mass spectrometers has superior limits of quantification, permitting omission of previously employed derivatization steps. The measurement of steroid profiles in the diagnosis and treatment of congenital adrenal hyperplasia, adrenal insufficiency, chronic pelvic pain and prostatitis, oncology (breast cancer), and athletes has important new applications. Conclusions: LC-MS/MS now affords the specificity, imprecision, and limits of quantification necessary for the reliable measurement of steroids in human fluids, enhancing diagnostic capabilities, particularly when steroid profiles are available.

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