scholarly journals Effect of Basic Cell-Penetrating Peptides on the Structural, Thermodynamic, and Hydrodynamic Properties of a Novel Drug Delivery Vector, ELP[V5G3A2-150]

Biochemistry ◽  
2014 ◽  
Vol 53 (6) ◽  
pp. 1081-1091 ◽  
Author(s):  
Daniel F. Lyons ◽  
Vu Le ◽  
Wolfgang H. Kramer ◽  
Gene L. Bidwell ◽  
Edwin A. Lewis ◽  
...  
Pharmaceutics ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 987
Author(s):  
Ülo Langel

In the most recent 25–30 years, multiple novel mechanisms and applications of cell-penetrating peptides (CPP) have been demonstrated, leading to novel drug delivery systems. In this review, I present a brief introduction to the CPP area with selected recent achievements. This is followed by a nostalgic journey into the research in my own laboratories, which lead to multiple CPPs, starting from transportan and paving a way to CPP-based therapeutic developments in the delivery of bio-functional materials, such as peptides, proteins, vaccines, oligonucleotides and small molecules, etc.


2019 ◽  
Vol 56 (2) ◽  
pp. 396-398
Author(s):  
Georgeta Zegan ◽  
Daniela Anistoroaei ◽  
Elena Mihaela Carausu ◽  
Eduard Radu Cernei ◽  
loredana Golovcencu

Amoxicillin and clavulanic acid are two of the most commonly prescribed antibacterial worldwide for treating oral infectious diseases. Oral health is of big importance for well-being and general health. A few novel drug delivery systems were designed for oral treatment and prophylaxis of different diseases in the oral cavity. This work focused on the latest drug delivery development of the most common oral pathologies, namely, periodontitis, oral mucosal infections, dental caries and oral cancer. Herein we reveal the synthesis, characterization and application of chitosan nanoparticles for intracellular transport of the weakly cell-penetrating amoxicillin and clavulanic acid in order to improve their efficacy on bacterial infections.


2010 ◽  
Vol 15 (23-24) ◽  
pp. 1103-1103
Author(s):  
Monerah H. Al-Soraj ◽  
Catherine L. Watkins ◽  
Dries Vercauteren ◽  
Stefaan De Smedt ◽  
Kevin Braeckmans ◽  
...  

ChemNanoMat ◽  
2020 ◽  
Vol 6 (8) ◽  
pp. 1138-1148
Author(s):  
Lin Gui ◽  
Xue‐Hao Zhang ◽  
Zeng‐Ying Qiao ◽  
Hao Wang

2019 ◽  
Vol 16 (9) ◽  
pp. 3727-3743 ◽  
Author(s):  
Shang Eun Park ◽  
Muhammad Imran Sajid ◽  
Keykavous Parang ◽  
Rakesh Kumar Tiwari

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