scholarly journals Spatial Mapping of Protein Adsorption on Mesoporous Silica Nanoparticles by Stochastic Optical Reconstruction Microscopy

2017 ◽  
Vol 139 (11) ◽  
pp. 3978-3981 ◽  
Author(s):  
Alden M. Clemments ◽  
Pablo Botella ◽  
Christopher C. Landry
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Protein Adsorption ◽  
Mesoporous Silica Nanoparticles ◽  
Spatial Mapping ◽  
Stochastic Optical Reconstruction Microscopy ◽  
Optical Reconstruction

A soft–hard template approach towards hollow mesoporous silica nanoparticles with rough surfaces for controlled drug delivery and protein adsorption

2015 ◽  
Vol 3 (31) ◽  
pp. 6480-6489 ◽  
Author(s):  
Haijiao Zhang ◽  
Huijuan Xu ◽  
Minghong Wu ◽  
Yufang Zhong ◽  
Donghai Wang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Protein Adsorption ◽  
Rough Surfaces ◽  
Mesoporous Silica Nanoparticles ◽  
Controlled Drug Delivery ◽  
Hard Template ◽  
Hollow Mesoporous Silica

Novel hollow mesoporous silica nanoparticles (HMSNs) with rough surfaces have been successfully prepared using a facile soft–hard template route.

scholarly journals Influence of serum concentration and surface functionalization on the protein adsorption to mesoporous silica nanoparticles

RSC Advances ◽  
2019 ◽  
Vol 9 (58) ◽  
pp. 33912-33921 ◽  
Author(s):  
Chih-Yu Lin ◽  
Chia-Min Yang ◽  
Mika Lindén
Keyword(s):  
Mesoporous Silica ◽  
Serum Concentration ◽  
Silica Nanoparticles ◽  
Protein Adsorption ◽  
Surface Functionalization ◽  
Mesoporous Silica Nanoparticles ◽  
Serum Concentrations ◽  
Functional Derivatives

In this work, protein adsorption on MSNs at in vitro (10%) and in vivo (100%) relevant serum concentrations was studied using three types of MSNs and their functional derivatives.

Recent Advances in Application of Azobenzenes Grafted on Mesoporous Silica Nanoparticles in Controlled Drug Delivery Systems Using Light as External Stimulus

2020 ◽  
Vol 20 (11) ◽  
pp. 1001-1016
Author(s):  
Sandra Ramírez-Rave ◽  
María Josefa Bernad-Bernad ◽  
Jesús Gracia-Mora ◽  
Anatoly K. Yatsimirsky
Keyword(s):  
Drug Delivery ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Drug Delivery Systems ◽  
Mesoporous Silica Nanoparticles ◽  
High Surface ◽  
Delivery Systems ◽  
Surface Reactivity ◽  
External Stimulus ◽  
Recent Advances

Hybrid materials based on Mesoporous Silica Nanoparticles (MSN) have attracted plentiful attention due to the versatility of their chemistry, and the field of Drug Delivery Systems (DDS) is not an exception. MSN present desirable biocompatibility, high surface area values, and a well-studied surface reactivity for tailoring a vast diversity of chemical moieties. Particularly important for DDS applications is the use of external stimuli for drug release. In this context, light is an exceptional alternative due to its high degree of spatiotemporal precision and non-invasive character, and a large number of promising DDS based on photoswitchable properties of azobenzenes have been recently reported. This review covers the recent advances in design of DDS using light as an external stimulus mostly based on literature published within last years with an emphasis on usually overlooked underlying chemistry, photophysical properties, and supramolecular complexation of azobenzenes.

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