Activatable NIR Fluorescence/MRI Bimodal Probes for in Vivo Imaging by Enzyme-Mediated Fluorogenic Reaction and Self-Assembly

2019 ◽  
Vol 141 (26) ◽  
pp. 10331-10341 ◽  
Author(s):  
Runqi Yan ◽  
Yuxuan Hu ◽  
Fei Liu ◽  
Shixuan Wei ◽  
Daqing Fang ◽  
...  
Keyword(s):  
Self Assembly ◽  
In Vivo Imaging ◽  
Nir Fluorescence ◽  
Fluorogenic Reaction

Development and in vivo imaging of a PET/MRI nanoprobe with enhanced NIR fluorescence by dye encapsulation

Nanomedicine ◽  
2012 ◽  
Vol 7 (2) ◽  
pp. 219-229 ◽  
Author(s):  
Jun Sung Kim ◽  
Young-Hwa Kim ◽  
Jin Hyun Kim ◽  
Keon Wook Kang ◽  
Eunju Lee Tae ◽  
...  
Keyword(s):  
In Vivo Imaging ◽  
Nir Fluorescence

scholarly journals Rational design of a NIR-II fluorescent nano-system with maximized fluorescence performance and applications

2021 ◽  
Author(s):  
Haoli Yu ◽  
Yuesong Wang ◽  
Yan Chen ◽  
Min Ji
Keyword(s):  
Fluorescence Imaging ◽  
In Vivo Imaging ◽  
Rational Design ◽  
Near Infrared ◽  
Nir Fluorescence

Purpose: Near-infrared (NIR) fluorescence imaging (FI) become a research hotspot in the field of in vivo imaging. Here, we intend to synthesize a NIR-II fluorescence nano-system with an excellent fluorescence...

Recent advances in stimuli-responsive in situ self-assembly of small molecule probes for in vivo imaging of enzymatic activity

2021 ◽  
Author(s):  
Yuqi Wang ◽  
Jianhui Weng ◽  
Xidan Wen ◽  
Yuxuan Hu ◽  
Deju Ye
Keyword(s):  
Enzymatic Activity ◽  
Small Molecule ◽  
Self Assembly ◽  
In Vivo Imaging ◽  
Molecular Probes ◽  
Stimuli Responsive ◽  
Small Molecule Probes ◽  
Recent Advances

Stimuli-responsive in situ self-assembly of small molecule probes into nanostructures has been promising for the construction of molecular probes for in vivo imaging.

Near-infrared Emitting Gold-silver Nanoclusters with Large Stokes Shift for Two-Photon in Vivo Imaging

2021 ◽  
Author(s):  
Yaowei Peng ◽  
Xiaoyu Huang ◽  
Fu Wang
Keyword(s):  
In Vivo Imaging ◽  
Near Infrared ◽  
Stokes Shift ◽  
Silver Nanoclusters ◽  
One Pot ◽  
Two Photon ◽  
Nir Fluorescence ◽  
Gold Silver ◽  
Stokes Shifts

Near-infrared emitting bi-metallic gold/silver nanoclusters with great stokes shifts were manufactured through one-pot synthesis. The gold/silver nanoclusters exhibit strong NIR fluorescence due to the silver effect, which can be applied...

A fluorinated aza-BODIPY derivative for NIR fluorescence/PA/19F MR tri-modality in vivo imaging

2019 ◽  
Vol 55 (42) ◽  
pp. 5851-5854 ◽  
Author(s):  
Lianhua Liu ◽  
Yaping Yuan ◽  
Yuqi Yang ◽  
Michael T. McMahon ◽  
Shizhen Chen ◽  
...  
Keyword(s):  
Contrast Agent ◽  
Small Molecule ◽  
In Vivo Imaging ◽  
Near Infrared ◽  
Tumor Imaging ◽  
Near Infrared Fluorescence ◽  
Highly Efficient ◽  
Nir Fluorescence

A fluorinated aza-BODIPY derivative BDPF was developed as a small molecule contrast agent, which displayed highly efficient near infrared fluorescence/photoacoustic/19F MR tri-modality tumor imaging.

Electrohydrodynamic Sprayable Amphiphilic Polysaccharide-Clasped Nanoscale Self-Assembly for In Vivo Imaging

2020 ◽  
Vol 12 (35) ◽  
pp. 38899-38905
Author(s):  
Jeong Chan Park ◽  
Do Hyeon Kim ◽  
Young Hoon Song ◽  
Hyung Joon Cha ◽  
Jeong Hyun Seo
Keyword(s):  
Self Assembly ◽  
In Vivo Imaging

scholarly journals In Vivo Imaging of Click-Crosslinked Hydrogel Depots Following Intratympanic Injection

Materials ◽  
2020 ◽  
Vol 13 (14) ◽  
pp. 3070
Author(s):  
Hyeon Jin Ju ◽  
Mina Park ◽  
Ji Hoon Park ◽  
Gi Ru Shin ◽  
Hak Soo Choi ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Hyaluronic Acid ◽  
Residence Time ◽  
In Vivo Imaging ◽  
Near Infrared ◽  
Tympanic Cavity ◽  
Nir Fluorescence ◽  
Degradation Pattern ◽  
Intratympanic Injection

In this study, we developed injectable intratympanic hyaluronic acid (HA) depots for the treatment of hearing loss. We prepared an injectable click-crosslinking formulation by modifying HA with tetrazine (HA-TET) and trans-cyclooctene (HA-TCO), which crosslinked to form an HA depot (Cx-HA). Preparation of the click-crosslinking HA formulation was facile, and Cx-HA depot formation was reproducible. Additionally, the Cx-HA hydrogel was significantly stiffer than HA hydrogel. To monitor the degradation pattern of hydrogels, we mixed a zwitterionic near-infrared (NIR) fluorophore (e.g., ZW800-1C) in the click-crosslinking HA formulation. Then, HA-TET and HA-TCO solutions containing ZW800-1C were loaded separately into the compartments of a dual-barrel syringe for intratympanic injection. The Cx-HA depots formed quickly, and an extended residence time in the tympanic cavity was confirmed by performing NIR fluorescence imaging. We have successfully prepared an injectable click-crosslinking HA formulation that has promise as an intratympanic drug depot.

scholarly journals Er3+-Ions-Doped Multiscale Nanoprobes for Fluorescence Imaging in Cellular and Living Mice

Nanomaterials ◽  
2021 ◽  
Vol 11 (10) ◽  
pp. 2676
Author(s):  
Cong Cao ◽  
Yu Xie ◽  
Shi-Wen Li ◽  
Chang Hong
Keyword(s):  
Light Scattering ◽  
Fluorescence Imaging ◽  
In Vivo Imaging ◽  
Near Infrared ◽  
Cell Imaging ◽  
Diagnostic Techniques ◽  
Single Nanoparticle ◽  
Nir Fluorescence ◽  
Nir Luminescence

With the development of biotechnology, luminescent nanoprobes for biological disease detection are widely used. However, the further application in clinic is limited by the reduced penetration depth in the tissues and light scattering. In this work, we have synthesized NaYF4:Yb,Er,Ce@SiO2-OAlg nanomaterials, which have both upconversion and near-infrared (NIR) luminescence. The optimized probes were determined to achieve cell imaging by its upconversion (UCL) luminescence and in vivo imaging through collection of NIR fluorescence signals simultaneously. The research is conducive to developing accurate diagnostic techniques based on UCL and NIR fluorescence imaging by a single nanoparticle.

In vitro and in vivo polysaccharides assembly: ultrastructural and cytochemical study of growing plant cell wall components.

1978 ◽  
Vol 36 (2) ◽  
pp. 434-435
Author(s):  
D. Reis ◽  
B. Vian ◽  
J. C. Roland
Keyword(s):  
Cell Wall ◽  
Self Assembly ◽  
Plant Cell Wall ◽  
Higher Plants ◽  
Three Dimensional ◽  
Cytochemical Study ◽  
Wall Components

Wall morphogenesis in higher plants is a problem still open to controversy. Until now the possibility of a transmembrane control and the involvement of microtubules were mostly envisaged. Self-assembly processes have been observed in the case of walls of Chlamydomonas and bacteria. Spontaneous gelling interactions between xanthan and galactomannan from Ceratonia have been analyzed very recently. The present work provides indications that some processes of spontaneous aggregation could occur in higher plants during the formation and expansion of cell wall.Observations were performed on hypocotyl of mung bean (Phaseolus aureus) for which growth characteristics and wall composition have been previously defined.In situ, the walls of actively growing cells (primary walls) show an ordered three-dimensional organization (fig. 1). The wall is typically polylamellate with multifibrillar layers alternately transverse and longitudinal. Between these layers intermediate strata exist in which the orientation of microfibrils progressively rotates. Thus a progressive change in the morphogenetic activity occurs.

Sign in / Sign up

Export Citation Format

Share Document