Effect of Ethylene Glycol and Polyethylene Glycol on the Acid-Unfolded State of Trypsinogen

2003 ◽  
Vol 22 (7/8) ◽  
pp. 677-682 ◽  
Author(s):  
Farah Naseem ◽  
Rizwan Hasan Khan
Keyword(s):  
Polyethylene Glycol ◽  
Ethylene Glycol ◽  
Unfolded State

scholarly journals Study of the properties of Ce3+-doped fluoride nanophosphors: phase composition, morphology, luminescence

2021 ◽  
Vol 2056 (1) ◽  
pp. 012048
Author(s):  
A M Dorokhina ◽  
V V Bakhmetyev ◽  
H Kominami ◽  
A Toru ◽  
M Hisashi
Keyword(s):  
Particle Size ◽  
Photodynamic Therapy ◽  
Phase Composition ◽  
Polyethylene Glycol ◽  
Ethylene Glycol ◽  
Solvothermal Synthesis ◽  
Luminescent Properties ◽  
Optimal Duration ◽  
Oncological Diseases ◽  
Synthesis Medium

Abstract To date, nanophosphors have found application in various fields, one of which is medicine. These phosphors were developed with the aim to become one of the components of a drug for photodynamic therapy of oncological diseases. The aim of this work was to study the effect of the duration, environment, and stabilizers of solvothermal synthesis on the microstructure and luminescent properties of the YF3:Ce nanophosphor. The solvothermal synthesis technique was carried out in three different media: water, ethanol, and ethylene glycol. The optimal duration of the synthesis was also determined (the synthesis was carried out at a temperature of 200°C for 4…20 hours). The dependence of the YF3 luminescence on the phase composition and the solvothermal synthesis medium was studied. Using SEM, the morphology and particle size of YF3:Ce phosphors were studied depending on different stabilizers (polyethylene glycol, polyethyleneimine, polyvinylpyrrolidone). The luminescence intensity of YF3:Ce and Na(Y1,5Na0,5)F6:Ce samples was compared.

Preparation of amphiphilic block copolymers (polyethylene adipate-block-polyethylene glycol) and its application in rotogravure ink formulations

2018 ◽  
Vol 47 (5) ◽  
pp. 415-423 ◽  
Author(s):  
Yasser Assem ◽  
Heba A. Mohamed ◽  
Rana Said ◽  
Ahmed El-Masry
Keyword(s):  
Optical Properties ◽  
Polyethylene Glycol ◽  
Block Copolymers ◽  
Ethylene Glycol ◽  
Adipic Acid ◽  
Amphiphilic Block Copolymers ◽  
Synthesis Process ◽  
Gravimetric Analysis ◽  
Content Type ◽  
Molecular Weights

Purpose The purpose of this paper is to prepare amphiphilic block copolymers polyethylene adipate-block-polyethylene glycol (PEA-b-PEG)s and study their performance as plasticizers in rotogravure ink formulations. Design/methodology/approach Series of amphiphilic block copolymers (PEA-b-PEG1), (PEA-b-PEG2), (PEA-b-PEG3), (PEA-b-PEG4) and (PEA-b-PEG5) were prepared by the reaction of adipic acid, ethylene glycol and polyethylene glycol of different molecular weights (300, 1,000, 2,000, 10,000 and 20,000 g/mol), respectively. Full characterization of the prepared copolymers was achieved using Fourier Transfer Infrared Spectroscopy (FTIR), 1H NMR, thermal gravimetric analysis (TGA) and differential scanning calorimetry (DSC). The performance of the prepared copolymers as plasticizers for neat nitrocellulose resin were studied in different formulations, namely, R1, R2, R3, R4 and R5 containing copolymers (PEA-b-PEG1), (PEA-b-PEG2), (PEA-b-PEG3), (PEA-b-PEG4) and (PEA-b-PEG5), respectively. In addition to formula R0 that contains acetyl tributyl citrate (ATBC) as a commercial plasticizer. The mechanical properties, thermal analysis (DSC, TGA) and optical properties of the prepared formulations films were investigated. Theses amphiphilic block copolymers were then applied as plasticizers in different rotogravure ink formulations (F1, F2, F3, F4 and F5) and compared with commercial rotogravure ink formula (F0). The color measurements and optical properties of all formulations were achieved. Findings It was found that the performance of the prepared copolymers as plasticizers in different formulations based on nitro cellulose resin gives better gloss, adhesion for R1 compared with the other samples and color strength for F1 compared with F0. Finally, all the samples gave excellent plasticizing effect. Research limitations/implications The authors believe that type of these materials open the way for a new class of plasticizers that upon application or even degradation gives small ecofriendly molecules (adipic acid and or ethylene glycol moieties) taking into consideration the simplicity of the rout of the synthesis process. Practical implications The prepared ecofriendly (PEA-b-PEG)s could be successfully used as plasticizers instead of commercial plasticizer ATBC. Originality/value The research provides that the prepared (PEA-b-PEG)s with different molecular weights can act as plasticizers in rotogravure ink formulations, and their performance was acceptable and available.

Comparison of two different methods for the vitrification of hatched blastocysts from the dromedary camel (Camelus dromedarius)

2005 ◽  
Vol 17 (5) ◽  
pp. 523 ◽  
Author(s):  
J. A. Skidmore ◽  
M. Billah ◽  
N. M. Loskutoff
Keyword(s):  
Polyethylene Glycol ◽  
Survival Rate ◽  
Ethylene Glycol ◽  
Liquid Nitrogen ◽  
Survival Rates ◽  
Camelus Dromedarius ◽  
Dromedary Camel ◽  
Vitrification Solution

The uteri of 32 donor camels were flushed non-surgically on Day 6, 7 or 8 after ovulation and a total of 184 embryos was recovered. Sixty Day 6 embryos and 61 Day 7 embryos were vitrified or frozen ultrarapidly using open pulled straws and a modified version of the Vajta protocol. These embryos were subjected to concentrations of either 10% and 20% or 20% and 40% ethanediol as the cryoprotectant before being loaded into open pulled straws (OPS) and plunged into liquid nitrogen. All embryos were subsequently thawed and rehydrated either directly into holding media or into holding media containing 0.2 m sucrose and were incubated for 5 or 10 min before being transferred to holding media before transfer to recipients. Although the survival rate of the embryos immediately after thawing was high (OPS 20%/40% ethanediol resulted in 97% and 100% survival for Day 6 and Day 7 embryos, respectively; OPS 10%/20% ethanediol resulted in 90% and 70% survival for Day 6 and Day 7 embryos, respectively), after 2 h in culture, survival rates had decreased to 46% and 53% for Day 6 and Day 7 embryos, respectively, using OPS 10%/20% and 53% and 63% for Day 6 and Day 7 embryos, respectively, using OPS 20%/40%; however, none of the embryos transferred resulted in a viable fetus. A further 63 embryos (Day 6: n = 31; Day 7: n = 16; Day 8: n = 16) were subsequently exposed to vitrification solution (20% glycerol + 20% ethylene glycol + 0.3 m sucrose + 0.375 m glucose + 3% polyethylene glycol) in three steps and after loading into 0.25 mL straws were plunged into liquid nitrogen. However, a much greater percentage of the Day 7 and Day 8 embryos (43.8% and 81.2% respectively) were fractured or torn after warming and none of the 12 intact embryos transferred resulted in a pregnancy. Better survival rates immediately after thawing and rehydration were obtained with the smaller Day 6 embryos (94%), which resulted in a total of eight fetuses from the 21 embryos transferred.

Modification of Soy Protein Isolate-Polyethylene Glycol Composite Packaging Films with Ethylene Glycol

2015 ◽  
Vol 731 ◽  
pp. 565-568
Author(s):  
Pei Wang ◽  
Zhen Huang ◽  
Wei Zheng ◽  
Ma Dong Si
Keyword(s):  
Polyethylene Glycol ◽  
Ethylene Glycol ◽  
Soy Protein ◽  
Soy Protein Isolate ◽  
Protein Isolate ◽  
Raw Material ◽  
Casting Method ◽  
Elongation At Break ◽  
E Coli ◽  
Solution Casting Method

With soy protein isolate (SPI) as the main raw material, and ethylene glycol (EG) and polyethylene glycol (PEG) as two additives, a number of SPI-based films were prepared through the solution casting method. Results show that the film flexibility is obviously improved after adding EG and the film tensile strength and elongation at break could reach more than 10.5 MPa and 140%, respectively. The antimicrobial results exhibit EG has higher antibacterial effect against both bacteria ofE. coliandS. aureusthan PEG-400.

Development of Environmentally Friendly Binder in Extrusion Molding

2014 ◽  
Vol 941-944 ◽  
pp. 1735-1739
Author(s):  
Xiao Wei Meng
Keyword(s):  
Polyethylene Glycol ◽  
Ethylene Glycol ◽  
Ethyl Cellulose ◽  
Environmentally Friendly ◽  
High Strength ◽  
Cemented Carbide ◽  
Homogeneous Microstructure ◽  
Polyoxyethylene Ether ◽  
Thermodynamic Conditions ◽  
Stable Performance

A new kind of binder was developed in extrusion molding. It included four ingredients: ethylene glycol acetate (60%~85% (mass/mass, as follows)), ethyl cellulose (10%~30%), ethylene glycol polyoxyethylene ether (5%~10%), polyethylene glycol stearate (0.8%~3%). The components of binder were compatible with thermodynamic conditions, so the binder was well-distributed in molecule level. The new binder is actual nontoxic, secure and environmentally friendly. The forming property of the binder is so excellent that it can load 54% ~ 56% (vol. /vol.) cemented carbide powders. The rods produced by this new binder provide high strength, stable performance, homogeneous microstructure.

Reappearance of slow mode in mixtures of polyethylene glycol and poly(sodium methacrylate)

Soft Matter ◽  
2018 ◽  
Vol 14 (24) ◽  
pp. 5039-5047
Author(s):  
Ksenija Kogej ◽  
Jaka Štirn ◽  
Jurij Reščič
Keyword(s):  
Polyethylene Glycol ◽  
Light Scattering ◽  
Dynamic Light Scattering ◽  
Ethylene Glycol ◽  
Slow Mode ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene ◽  
Scattering Signal ◽  
Sodium Methacrylate

After addition of poly(ethylene glycol) to a solution of poly(sodium methacrylate), the slow-mode dynamic light scattering signal reappears.

Alternative polymer precipitants for protein crystallization

2010 ◽  
Vol 43 (4) ◽  
pp. 737-742 ◽  
Author(s):  
Tereza Skálová ◽  
Jarmila Dušková ◽  
Jindřich Hašek ◽  
Petr Kolenko ◽  
Andrea Štěpánková ◽  
...  
Keyword(s):  
Polyethylene Glycol ◽  
Ethylene Glycol ◽  
Protein Crystallization ◽  
Glycol Adipate ◽  
Poly Ethylene Glycol ◽  
Ph Values ◽  
Ethylene Glycol Adipate ◽  
Acid Sodium Salt ◽  
Poly Ethylene ◽  
Glycol Methyl Ether

A set of 16 inexpensive and commercially available polymer precipitants were tested for protein crystallization. Eight of them were found suitable: polyethylene glycol dimethyl ether of molecular weight (MW) 500, 1000 and 2000; di[poly(ethylene glycol)] adipate, MW 900; poly(ethylene glycol-ran-propylene glycol), MW 2500 and 12000; poly(acrylic acid) sodium salt, MW 2100; and polyethylene glycol methyl ether methacrylate, MW 1100. Two new crystallization screens, PolyA and PolyB, were formulated using these eight polymers, each containing 96 solutions – four polymers in combination with 24 common salts and buffers, covering pH values from 4.5 to 9.0. The screens were tested on 29 proteins, 21 of which were crystallized. The tests confirmed the applicability of the eight polymers as precipitants for protein crystallization.

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