Changes in Swallowing-Related Tachycardia and Respiratory Arrhythmia Induced by Modulation of Tonic Parasympathetic Influences

2003 ◽  
Vol 35 (6) ◽  
pp. 434-444 ◽  
Author(s):  
O. P. Sheroziya ◽  
V. V. Ermishkin ◽  
E. V. Lukoshkova ◽  
E. P. Mazygula ◽  
V. B. Ryb'yakova ◽  
...  
1995 ◽  
Vol 32 (4) ◽  
pp. 329-334 ◽  
Author(s):  
RICHARD J. CONTRADA ◽  
ALBERTO BO ◽  
LINDA LEVY ◽  
THEODORE WEISS

2009 ◽  
Vol 106 (1) ◽  
pp. 29-39 ◽  
Author(s):  
Michela Masè ◽  
Marcello Disertori ◽  
Flavia Ravelli

Respiratory sinus arrhythmia (RSA) is generally known as the autonomically mediated modulation of the sinus node pacemaker frequency in synchrony with respiration. Cardiorespiratory interactions have been largely investigated during sinus rhythm, whereas little is known about interactions during reentrant arrhythmias. In this study, cardiorespiratory interactions at the atrial and ventricular level were investigated during atrial flutter (AFL), a supraventricular arrhythmia based on a reentry, by using cross-spectral analysis and computer modeling. The coherence and phase between respiration and atrial (γ[Formula: see text], φAA) and ventricular (γ[Formula: see text], φRR) interval series were estimated in 20 patients with typical AFL (68.0 ± 8.8 yr) and some degree of atrioventricular (AV) conduction block. In all patients, atrial intervals displayed oscillations strongly coupled and in phase with respiration (γ[Formula: see text]= 0.97 ± 0.05, φAA = 0.71 ± 0.31 rad), corresponding to a paradoxical lengthening of intervals during inspiration. The modulation pattern was frequency independent, with in-phase oscillations and short time delays (0.40 ± 0.15 s) for respiratory frequencies in the range 0.1–0.4 Hz. Ventricular patterns were affected by AV conduction type. In patients with fixed AV conduction, ventricular intervals displayed oscillations strongly coupled (γ[Formula: see text]= 0.97 ± 0.03) and in phase with respiration (φRR = 1.08 ± 0.80 rad). Differently, in patients with variable AV conduction, respiratory oscillations were secondary to Wencheback rhythmicity, resulting in a decreased level of coupling (γ[Formula: see text]= 0.50 ± 0.21). Simulations with a simplified model of AV conduction showed ventricular patterns to originate from the combination of a respiratory modulated atrial input with the functional properties of the AV node. The paradoxical frequency-independent modulation pattern of atrial interval, the short time delays, and the complexity of ventricular rhythm characterize respiratory arrhythmia during AFL and distinguish it from normal RSA. These peculiar features can be explained by assuming a direct mechanical action of respiration on AFL reentrant circuit.


2001 ◽  
Vol 280 (1) ◽  
pp. H401-H406 ◽  
Author(s):  
Carl J. Meurling ◽  
Johan E. P. Waktare ◽  
Fredrik Holmqvist ◽  
Antti Hedman ◽  
A. John Camm ◽  
...  

High-resolution digital Holter recording was carried out in 21 patients (15 men, 64 ± 12 yr) with chronic atrial fibrillation. Dominating atrial cycle length (DACL) was derived by frequency domain analysis of QRST-reduced electrocardiograms. Daytime mean DACL was 150 ± 17 ms, and nighttime mean was 157 ± 22 ms ( P = 0.0002). Diurnal fluctuation in DACL differed among patients: it tended to be virtually absent in those with a short mean DACL, but in those with longer DACL the night-day difference was as much as 23 ms ( R = 0.72, P < 0.001, correlation of mean DACL to night-day difference). Mean DACL also correlated with ventricular cycle length ( R = 0.40, P < 0.001), particularly at night ( r = 0.49). The shorter cycle lengths found in this study during the day are consistent with sympathetic and/or other physiological modulation, but since increased vagal tone shortens atrial refractoriness in most models, parasympathetic influences are not likely to play a major role. Alternatively, atrial effective refractory period may not be the sole determinant of atrial cycle length during atrial fibrillation.


1995 ◽  
Vol 198 (11) ◽  
pp. 2307-2315 ◽  
Author(s):  
P E Signore ◽  
D R Jones

Neural control of free and forced diving bradycardia and peripheral resistance was studied in the muskrat (Ondatra zibethicus) by means of acute pharmacological blockade with the muscarinic blocker atropine, the alpha-adrenergic blocker phentolamine and the beta-adrenergic blockers nadolol and propranolol. Saline injection was used as a control. Heart rate in control animals increased before voluntary dives and dropped markedly as soon as the animals submerged. Heart rate started increasing towards the end of voluntary dives and reached pre-dive values within the first 5 s of recovery. Pre-dive and post-dive tachycardia were reduced in beta-blocked animals, emphasizing the role of the sympathetic system during the preparatory and recovery periods of voluntary dives. Diving bradycardia and the acceleration in heart rate before surfacing were abolished by atropine and unaffected by nadolol, demonstrating the importance of vagal efferent activity during diving. The results after blockade with nadolol suggest that there is an accentuated antagonism between the two branches of the autonomic nervous system during diving, so that parasympathetic influences on the heart predominate. Propranolol-treated muskrats had a higher diving heart rate than saline- and nadolol-treated animals, which may be due to a sedative effect caused by propranolol crossing the blood-brain barrier, a blockade of central catecholaminergic pathways or a peripheral neural effect, due to the anaesthetic properties of propranolol. Phentolamine did not affect diving bradycardia, indicating that diving bradycardia occurs independently of peripheral vasoconstriction.(ABSTRACT TRUNCATED AT 250 WORDS)


2003 ◽  
Vol 6 (1) ◽  
pp. 60-78 ◽  
Author(s):  
Jaime Vila ◽  
María Carmen Fernández ◽  
Joaquín Pegalajar ◽  
María Nieves Vera ◽  
Humbelina Robles ◽  
...  

The study of cardiac defense has a long tradition in psychological research both within the cognitive approach—linked to Pavlov, Sokolov, and Graham's work on sensory reflexes—and within the motivational one—linked to the work of Cannon and subsequent researchers on the concepts of activation and stress. These two approaches have been difficult to reconcile in the past. We summarize a series of studies on cardiac defense from a different perspective, which allows integration of the traditional approaches. This new perspective emphasizes a sequential process interpretation of the cardiac defense response. Results of descriptive and parametric studies, as well as those of studies examining the physiological and psychological mechanisms underlying the response, show a complex response pattern with both accelerative and decelerative components, with both sympathetic and parasympathetic influences, and with both attentional and emotional significance. The implications of this new look at cardiac defense are discussed in relation to defensive reactions in natural settings, the brain mechanisms controlling such reactions, and their effects on health and illness.


2021 ◽  
Author(s):  
Y.Y. Bikbaeva ◽  
D.A. Pavlov ◽  
A.S. Kuznetsov ◽  
E.S. Balykina ◽  
I.V. Antipov

The effect of percutaneous electrical stimulation of the spinal cord on the reactions of the autonomic nervous system in patients after acute cerebral circulatory disorders was evaluated. Patients in the acute period of rehabilitation treatment underwent a course of percutaneous electrical stimulation for 10 days. Before and after rehabilitation, vegetative reactions were assessed using an orthoclinostatic test, an A.M.Wein questionnaire, and neurological disorders on the Scandinavian scale. The inclusion of the course of percutaneous electrical stimulation in the program of physical rehabilitation of patients who have suffered an ischemic stroke indicates an improvement in the motor status of patients and a decrease in the imbalance of sympathetic and parasympathetic influences Keywords: ischemic stroke, percutaneous electrical stimulation of the spinal cord, vegetative reactions


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