Technologies used to enhance, augment, or replace traditional course content have been widely examined. With few exceptions, study of these technologies focuses on the effects of the technologies in isolation. Only a few discussions have attempted to evaluate multi-technologies and their contribution to effective learning for online students. This chapter looks at the traditional learning styles and creates a model for robust, multi-technology, student learning-centered approach to optimize student learning in online classes in a business school. It finds that a well-designed, multi-technology approach results in better student performance, more satisfied students, and greater cost-benefit for the business school. The results have been adapted into course design to create a new kind of resource for online course deployment.