A dyadic approach to health, cognition, and quality of life in aging adults.

2015 ◽  
Vol 30 (2) ◽  
pp. 449-461 ◽  
Author(s):  
Kyle J. Bourassa ◽  
Molly Memel ◽  
Cindy Woolverton ◽  
David A. Sbarra
2002 ◽  
Vol 18 (3) ◽  
pp. 497-507 ◽  
Author(s):  
Andrew Clegg ◽  
Jackie Bryant ◽  
Tricia Nicholson ◽  
Linda McIntyre ◽  
Sofie De Broe ◽  
...  

Objectives: Systematic review of the clinical and cost-effectiveness of donepezil, rivastigmine, and galantamine for people suffering from Alzheimer's disease.Methods: Sixteen electronic databases (including MEDLINE, the Cochrane Library, and Embase) and bibliographies of related papers were searched for published/unpublished English language studies, and experts and pharmaceutical companies were consulted for additional information. Randomized controlled trials (RCTs) and economic studies were selected. Clinical effectiveness was assessed on measurement scales assessing progression of Alzheimer's disease on the person's global health, cognition, functional ability, behavior and mood, and quality of life. Cost-effectiveness was presented as incremental cost per year spent in a nonsevere state (by Mini Mental Health State Examination) or quality-adjusted life-year.Results: Twelve of 15 RCTs included were judged to be of good quality. Although donepezil had beneficial effects in Alzheimer's patients on global health and cognition, rivastigmine on global health, and galantamine on global health, cognition, and functional scales, these improvements were small and may not be clinically significant. Measures of quality of life and behavior and mood were rarely assessed. Adverse effects were usually mild and transient. Cost-effectiveness base case estimates ranged from £2,415 savings to £49,476 additional cost (1997 prices) per unit of effect for donepezil and a small savings for rivastigmine. Estimates were not considered robust or generalizable.Conclusions: Donepezil, rivastigmine, and galantamine appear to have some clinical effect for people with Alzheimer's disease, although the extent to which these translate into real differences in everyday life remains unclear. Due to the nature of current economic studies, cost-effectiveness remains uncertain and the impact on different care sectors has been inadequately investigated. Further research is needed to establish the actual benefits of acetylcholinesterase inhibitors (AChEls) for people with Alzheimer's disease and their caregivers, the relationship of these changes to clinical management, and careful prospective evaluation of resource and budgetary consequences.


2010 ◽  
Vol 47 (3) ◽  
pp. 264-281 ◽  
Author(s):  
C. Sole ◽  
M. Mercadal-Brotons ◽  
S. Gallego ◽  
M. Riera
Keyword(s):  

2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. 964-964
Author(s):  
Jessika Dayrit ◽  
Ana maria Pasatiempo ◽  
Kevin Hitosis

Abstract Background Social isolation among older adults linked to serious health conditions. However, little is known if functional mobility among isolated aging adults impacts quality of life. Objectives: This study will examine the association between levels of functional mobilities and risks for developing depression, poor health status, and physical inactivity by controlling socioeconomic factors. Methods This is a cross-sectional study, using Behavioral Risk Factor Surveillance System (BRFSS) data 2017. Target population are over age 65 who are living alone (N=50,784). Outcome variables are depression, self-reported health status, and physical inactivity whereas main predictors are activities of daily living (ADL) and instrumental activities of daily living (IADL) controlling for gender, race, marital status, employment status, annual income, and educational level. Weight adjustment analysis and logistic regression were conducted. Results Depression, self-reported poor health status, and physical inactivity are higher among isolated aging adults who have limitations with ADL/IADL. Specifically, those with difficulties concentrating/decision making (OR=3.62; CI=3.35-3.91) have higher chance of developing depression than those who do not have this limitation. Female are at risk for developing depression (OR=1.41-1.61; CI=1.51), yet they are likely to report for better health status (OR=1.54; CI=1.45-1.64) than males. Asian (OR=0.56; CI=0.39-0381), Black or African American (OR=0.54; CI=0.48-0.60) are less likely to be diagnosed with depressive disorder than White. Discussion/Recommendation: Physical and cognitive changes that come with aging can pose challenge, as functional capacity diminishes in home environment. Further research should be explored in longitudinal studies on mobility and improving quality of living among isolated aging population.


2018 ◽  
Vol 31 (06) ◽  
pp. 789-797 ◽  
Author(s):  
Judith Godin ◽  
Joshua J. Armstrong ◽  
Lindsay Wallace ◽  
Kenneth Rockwood ◽  
Melissa K. Andrew

ABSTRACTBackground:How cognitive impairment and frailty combine to impact on older adults’ Quality of Life (QoL) is little studied, but their inter-relationships are important given how often they co-occur. We sought to examine how frailty and cognitive impairment, as well as changes in frailty and cognition, are associated with QoL and how these relationships differ based on employment status and social circumstances.Methods:Using the Survey of Health, Ageing, and Retirement in Europe data, we employed moderated regression, followed by simple slopes analysis, to examine how the relationships between levels of health (i.e., of frailty and cognition) and QoL varied as a function of sex, age, education, social vulnerability, and employment status. We used the same analysis to test whether the relationships between changes in health (over two years) and QoL varied based on these same moderators.Results:Worse frailty (b = −1.61, p < .001) and cognitive impairment (b = −0.08, p < .05) were each associated with lower QoL. Increase in frailty (b = −2.17, p < .001) and cognitive impairment (b = −0.25, p < .001) were associated with lower QoL. The strength of these relationships varied depending on interactions with age, sex, education, social vulnerability, and employment status. Higher social vulnerability was consistently associated with lower QoL in analyses examining both static health (b = −3.16, p < .001) and change in health (b = −0.66, p < .001).Conclusions:Many predictors of QoL are modifiable, providing potential targets to improve older adults’ QoL. Even so, the relationships between health, cognition, and social circumstances that shape QoL in older adults are complex, highlighting the importance for individualized interventions.


2020 ◽  
Vol 29 (4) ◽  
pp. 2097-2108
Author(s):  
Robyn L. Croft ◽  
Courtney T. Byrd

Purpose The purpose of this study was to identify levels of self-compassion in adults who do and do not stutter and to determine whether self-compassion predicts the impact of stuttering on quality of life in adults who stutter. Method Participants included 140 adults who do and do not stutter matched for age and gender. All participants completed the Self-Compassion Scale. Adults who stutter also completed the Overall Assessment of the Speaker's Experience of Stuttering. Data were analyzed for self-compassion differences between and within adults who do and do not stutter and to predict self-compassion on quality of life in adults who stutter. Results Adults who do and do not stutter exhibited no significant differences in total self-compassion, regardless of participant gender. A simple linear regression of the total self-compassion score and total Overall Assessment of the Speaker's Experience of Stuttering score showed a significant, negative linear relationship of self-compassion predicting the impact of stuttering on quality of life. Conclusions Data suggest that higher levels of self-kindness, mindfulness, and social connectedness (i.e., self-compassion) are related to reduced negative reactions to stuttering, an increased participation in daily communication situations, and an improved overall quality of life. Future research should replicate current findings and identify moderators of the self-compassion–quality of life relationship.


Sign in / Sign up

Export Citation Format

Share Document