The patient described by Wattad et al is quite similar to the two children we describe.1 Once again the striking features are acute flank pain and nonoliguric renal dysfunction. The renal biopsy demonstrates mild interstitial nephritis. We believe that knowledge of the association of this clinical syndrome with nonsteroidal anti-inflammatory drug use will make renal biopsy (and its potential complications) unnecessary in evaluating future cases. We strongly suspect that this condition is much more common than previously recognized.
The effect of aspirin and nonsteroidal anti-inflammatory drug use after diagnosis on survival of oesophageal cancer patients
