Blood pressure levels and control in Italy: comprehensive analysis of clinical data from 2000–2005 and 2005–2011 hypertension surveys

UNSTRUCTURED Lifestyle interventions have been recognised as a line treatment of non-communicable diseases. The aimed of this study was to evaluate a bespoke mHealth approach to delivers personalised feedback to improve blood pressure and weight for hypertensive patients in community settings. A total of 307 participants, 50 from each community, were expected to be in the intervention or control group. A professional health facilitator was assigned for each of the 6 communities. The primary outcomes of the study are the reduction in blood pressure and weight at baseline and post-intervention. Of 307 recruited,192 (62.5%) participants completed the study (intervention: 104 and control: 88). There was no difference in attrition rates between the two groups (33.5%vs41.9%, p=0.291). After 6-months of intensive feedback intervention through mHealth approach, patients had better blood pressure, weight, and BMI compared with control. People who were adherent to the intervention demonstrated a clinical benefit with regards to weight and blood pressure.

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Inorganic nitrate and nitrite and control of blood pressure

Cardiovascular Research ◽

10.1093/cvr/cvq309 ◽

2010 ◽

Vol 89 (3) ◽

pp. 492-498 ◽

Cited By ~ 77

Author(s):

Mark Gilchrist ◽

Angela C. Shore ◽

Nigel Benjamin

Keyword(s):

Blood Pressure ◽

Inorganic Nitrate ◽

Nitrate And Nitrite ◽

And Control

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Hypertension Prevalence, Awareness, Treatment, and Control: Should 24-Hour Ambulatory Blood Pressure Monitoring be the Tool of Choice?

Journal of Clinical Hypertension ◽

10.1111/jch.12737 ◽

2015 ◽

Vol 18 (7) ◽

pp. 697-702 ◽

Cited By ~ 1

Author(s):

Anne Marie O'Flynn ◽

Ronan J. Curtin ◽

Ivan J. Perry ◽

Patricia M. Kearney

Keyword(s):

Blood Pressure ◽

Ambulatory Blood Pressure Monitoring ◽

Ambulatory Blood Pressure ◽

Blood Pressure Monitoring ◽

Pressure Monitoring ◽

Hypertension Prevalence ◽

And Control

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Abstract P125: Hypertension, Awareness, Treatment, And Control In Nepal: Results From May Measurement Month 2020 Blood Pressure Screening

Hypertension ◽

10.1161/hyp.78.suppl_1.p125 ◽

2021 ◽

Vol 78 (Suppl_1) ◽

Author(s):

Pawan Acharya ◽

Sweta Koirala ◽

Pabitra Babu Soti ◽

Sneha Sharma ◽

Abhishek Sapkota ◽

...

Keyword(s):

Blood Pressure ◽

Smoking Status ◽

Blood Pressure Measurement ◽

Age Groups ◽

Hypertension Status ◽

Safety Measures ◽

Treatment Of Hypertension ◽

Hypertension Awareness ◽

The Mean ◽

And Control

Background: May Measurement Month (MMM) 2020 was not officially executed globally due to the COVID-19 pandemic. But in Nepal, the MMM 2020 was conducted by following COVID-19 safety measures. Methods: We used an opportunistic screening campaign for blood pressure measurement among individuals ≥18 years in Nepal. Of the three measurements, the second and third measurements were used to estimate the mean systolic and diastolic blood pressure(BP). We defined hypertension as the systolic BP ≥ 120 or diastolic BP≥90 mmHg and or currently taking antihypertensive medicine. Results: Among the total 11,486 participants, 57%(6568/11486) were females. The mean age of the screenees was 45years(SD=17.0). The mean systolic and diastolic BP were 125.8(SD= 18.0) and 81.6(SD=10.5) respectively. About 31.3%(3592/11481) participants had hypertension. Among the hypertensive persons, 40.2%(1444/3592) were aware of their hypertension status. Among these who were aware, 79.4%(1146/1444) were taking antihypertensive medicine. However, the overall proportion of hypertensive patients taking medicine was 32.0%(1146/3592). The BP was controlled among 46% ( 527/1444) of participants who were under medication. Logistic regression analysis adjusting age, sex, body mass index(BMI), and smoking status found males, higher age groups, higher BMI, and smokers had higher odds of being hypertensive. (Figure 1) Conclusion: The results suggest a need to address the gap in awareness, diagnosis, and treatment of hypertension in Nepal. The results are limited due to the non-random participation of screenees. Figure 1. Odds ratio plot

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Acute Blood Pressure Response to High- and Moderate-Speed Resistance Exercise in Older Adults With Hypertension

Journal of Aging and Physical Activity ◽

10.1123/japa.2021-0214 ◽

2021 ◽

pp. 1-8

Author(s):

Carlos Leonardo Figueiredo Machado ◽

Régis Radaelli ◽

Clarissa Muller Brusco ◽

Eduardo Lusa Cadore ◽

Eurico N. Wilhelm ◽

...

Keyword(s):

Blood Pressure ◽

Older Adults ◽

Resistance Exercise ◽

Blood Pressure Response ◽

Individual Response ◽

Older Individuals ◽

Repetition Maximum ◽

Control Protocol ◽

The Individual ◽

And Control

An increase in blood pressure (BP) occurs during resistance exercise; attention to this response may be necessary in older individuals with hypertension. We compared the BP responses following high- (HSRE) and moderate-speed resistance exercise (MSRE) (4 × 8 repetitions at 60% one-repetition maximum) and control protocol in 15 older adults with hypertension. HSRE and MSRE increased systolic BP (SBP) by the end of each set compared with preexercise and control protocol. Immediately after the fourth set, a higher SBP was observed in MSRE than HSRE (147 ± 14 vs. 141 ± 12 mmHg; p = .01). Taking an exploratory analysis of the individual response, we observed that MSRE resulted in greater mean changes and number of SBP exposures to values ≥150 mmHg (22-fold) than HSRE (10-fold). Diastolic BP increased (p < .05) with exercise, but only MSRE increased compared with the control condition (p < .05). HSRE may be an alternative for individuals in which SBP peak should be avoided.

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Abstract 15595: Missed Targets: United States Trends in Hypertension Prevalence, Control, and Treatment 2005-2018

Circulation ◽

10.1161/circ.142.suppl_3.15595 ◽

2020 ◽

Vol 142 (Suppl_3) ◽

Author(s):

Rahul Aggarwal ◽

Nicholas Chiu ◽

Rishi Wadhera ◽

Changyu Shen ◽

Robert W Yeh ◽

...

Keyword(s):

Blood Pressure ◽

Temporal Trends ◽

Cost Effective ◽

Pressure Control ◽

Healthy People ◽

Sensitivity Analyses ◽

Base Case ◽

Improve Blood Pressure Control ◽

Hypertension Prevalence ◽

And Control

Introduction: Hypertension is a major risk factor for cardiovascular disease. The US government, through the Healthy People Initiative 2020, set targets to improve hypertension prevalence and treatment rates in US adults by a relative 10% from 2005 to 2020, and increase control rates by a relative 40%. We examined US progress towards this goal from 2005-2018. Methods: We analyzed data from 38,876 non-pregnant US adults from the NHANES 2005-2018 surveys to determine nationally representative estimates of hypertension prevalence, treatment rates, and control. Temporal trends in hypertension prevalence, treatment, and control were assessed using weighted linear regression after age adjustment to the 2000 US census (per the Healthy People Initiative approach). In the base case, we defined hypertension as blood pressure >140/90 or on an antihypertensive; we used the ACC/AHA definition of blood pressure >130/80 in sensitivity analyses. Results: In 2017-2018, 34.3% (±1.7) of US adults had hypertension, of these 69.7% (±1.5) were on treatment, and 43.7% (±1.6) were controlled. After age-adjustment, no statistically significant changes in hypertension prevalence, treatment rates, or control were observed from 2005-2018 (p for trend 0.91, ,0.98, 0.66, Figure 1). In sensitivity analyses, applying the ACC/AHA definition increased the estimated prevalence of hypertension during the period, but trends in prevalence remained unchanged. Conclusions: There has been no material progress in reducing the prevalence of hypertension or improving rates of treatment and control from 2005 to 2018. As planning is underway for Healthy People Initiative 2030, setting of hypertension targets must be accompanied with investments in cost-effective, scalable programs to improve blood pressure control nationwide, with a focus on high-risk populations.

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Interleukin-1β and neurogenic control of blood pressure in normal rats and rats with chronic renal failure

AJP Heart and Circulatory Physiology ◽

10.1152/ajpheart.2000.279.6.h2786 ◽

2000 ◽

Vol 279 (6) ◽

pp. H2786-H2796 ◽

Cited By ~ 25

Author(s):

Shaohua Ye ◽

Pantea Mozayeni ◽

Michael Gamburd ◽

Huiqin Zhong ◽

Vito M. Campese

Keyword(s):

Nitric Oxide ◽

Blood Pressure ◽

Renal Failure ◽

Nervous System ◽

Chronic Renal Failure ◽

Lateral Ventricle ◽

Mrna Abundance ◽

And Control ◽

The Brain ◽

Local Expression

Increased sympathetic nervous system (SNS) activity plays a role in the genesis of hypertension in rats with chronic renal failure (CRF). The rise in central SNS activity is mitigated by increased local expression of neuronal nitric oxide synthase (NOS) mRNA and NO2/NO3 production. Because interleukin (IL)-1β may activate nitric oxide in the brain, we have tested the hypothesis that IL-1β may modulate the activity of the SNS via regulation of the local expression of neuronal NOS (nNOS) in the brain of CRF and control rats. To this end, we first found that administration of IL-1β in the lateral ventricle of control and CRF rats decreased blood pressure and norepinephrine (NE) secretion from the posterior hypothalamus (PH) and increased NOS mRNA expression. Second, we observed that an acute or chronic injection of an IL-1β-specific antibody in the lateral ventricle raised blood pressure and NE secretion from the PH and decreased NOS mRNA abundance in the PH of control and CRF rats. Finally, we measured the IL-1β mRNA abundance in the PH, locus coeruleus, and paraventricular nuclei of CRF and control rats by RT-PCR and found it to be greater in CRF rats than in control rats. In conclusion, these studies have shown that IL-1β modulates the activity of the SNS in the central nervous system and that this modulation is mediated by increased local expression of nNOS mRNA.

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24-Hour ambulatory blood pressure levels and control in a large cohort of adult outpatients with different classes of obesity

Journal of Human Hypertension ◽

10.1038/s41371-018-0132-4 ◽

2018 ◽

Vol 33 (4) ◽

pp. 298-307 ◽

Cited By ~ 2

Author(s):

Ilaria Figliuzzi ◽

Vivianne Presta ◽

Francesca Miceli ◽

Barbara Citoni ◽

Roberta Coluccia ◽

...

Keyword(s):

Blood Pressure ◽

Ambulatory Blood Pressure ◽

Large Cohort ◽

And Control

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Nucleus tractus solitarius and control of blood pressure in chronic sinoaortic denervated rats

AJP Regulatory Integrative and Comparative Physiology ◽

10.1152/ajpregu.1992.263.2.r258 ◽

1992 ◽

Vol 263 (2) ◽

pp. R258-R266 ◽

Cited By ~ 28

Author(s):

A. M. Schreihofer ◽

A. F. Sved

Keyword(s):

Blood Pressure ◽

Plasma Levels ◽

Nucleus Tractus Solitarius ◽

Inhibitory Influence ◽

Baroreceptor Reflexes ◽

Alpha Chloralose ◽

And Control ◽

Bilateral Destruction ◽

Conscious Control

To determine the role of the nucleus tractus solitarius (NTS) in the tonic maintenance of arterial pressure (AP) following chronic baroreceptor denervation, the present study examined the effect of inhibition of the NTS on AP in chronic sinoaortic denervated (SAD) and control rats. One to two weeks after complete SAD (no residual arterial baroreceptor reflexes) mean AP was not significantly different from that of control rats. Bilateral microinjections of muscimol and lidocaine into the NTS markedly increased AP in alpha-chloralose-anesthetized control rats. However, microinjections of these neuroinhibitory drugs had no effect on AP in SAD rats. Similarly, 1 h after bilateral destruction of the NTS conscious control rats were hypertensive, while AP in SAD rats was not changed. Plasma levels of vasopressin (VP), which were also elevated in control rats 1 h after NTS lesions, were not significantly altered in SAD rats. These results demonstrate that inhibition of the NTS has no effect on AP or plasma levels of VP in chronic SAD rats. This suggests neither the NTS nor afferents to the NTS supply a tonic inhibitory influence on AP after chronic baroreceptor denervation.

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