Vigorous physical activity slows progression of prostate cancer in older men

2005 ◽  
Vol 2 (6) ◽  
pp. 268-269
Keyword(s):  
Physical Activity ◽  
Prostate Cancer ◽  
Vigorous Physical Activity ◽  
Older Men

scholarly journals Obesity and low levels of physical activity impact on cardiopulmonary fitness in older men after treatment for prostate cancer

2021 ◽  
Author(s):  
Sara Faithfull ◽  
Agnieszka Lemanska ◽  
Karen Poole ◽  
Jonathan Aning ◽  
Ralph Manders ◽  
...  
Keyword(s):  
Physical Activity ◽  
Prostate Cancer ◽  
Older Men ◽  
Cardiopulmonary Fitness ◽  
Low Levels

scholarly journals Objectively measured physical activity, sedentary behaviour and all-cause mortality in older men: does volume of activity matter more than pattern of accumulation?

2018 ◽  
Vol 53 (16) ◽  
pp. 1013-1020 ◽  
Author(s):  
Barbara J Jefferis ◽  
Tessa J Parsons ◽  
Claudio Sartini ◽  
Sarah Ash ◽  
Lucy T Lennon ◽  
...  
Keyword(s):  
Physical Activity ◽  
Sedentary Behaviour ◽  
Vigorous Physical Activity ◽  
Older Men ◽  
Population Based ◽  
Physical Activity Guidelines ◽  
All Cause Mortality ◽  
Sedentary Breaks ◽  
Objectively Measured

ObjectivesTo understand how device-measured sedentary behaviour and physical activity are related to all-cause mortality in older men, an age group with high levels of inactivity and sedentary behaviour.MethodsProspective population-based cohort study of men recruited from 24 UK General Practices in 1978–1980. In 2010–2012, 3137 surviving men were invited to a follow-up, 1655 (aged 71–92 years) agreed. Nurses measured height and weight, men completed health and demographic questionnaires and wore an ActiGraph GT3x accelerometer. All-cause mortality was collected through National Health Service central registers up to 1 June 2016.ResultsAfter median 5.0 years’ follow-up, 194 deaths occurred in 1181 men without pre-existing cardiovascular disease. For each additional 30 min in sedentary behaviour, or light physical activity (LIPA), or 10 min in moderate to vigorous physical activity (MVPA), HRs for mortality were 1.17 (95% CI 1.10 to 1.25), 0.83 (95% CI 0.77 to 0.90) and 0.90 (95% CI 0.84 to 0.96), respectively. Adjustments for confounders did not meaningfully change estimates. Only LIPA remained significant on mutual adjustment for all intensities. The HR for accumulating 150 min MVPA/week in sporadic minutes (achieved by 66% of men) was 0.59 (95% CI 0.43 to 0.81) and 0.58 (95% CI 0.33 to 1.00) for accumulating 150 min MVPA/week in bouts lasting ≥10 min (achieved by 16% of men). Sedentary breaks were not associated with mortality.ConclusionsIn older men, all activities (of light intensity upwards) were beneficial and accumulation of activity in bouts ≥10 min did not appear important beyond total volume of activity. Findings can inform physical activity guidelines for older adults.

scholarly journals A Clinician Referral and 12-Week Exercise Training Program for Men With Prostate Cancer: Outcomes to 12 Months of the ENGAGE Cluster Randomized Controlled Trial

2017 ◽  
Vol 14 (5) ◽  
pp. 353-359 ◽  
Author(s):  
Cadeyrn J. Gaskin ◽  
Melinda Craike ◽  
Mohammadreza Mohebbi ◽  
Kerry S. Courneya ◽  
Patricia M. Livingston
Keyword(s):  
Physical Activity ◽  
Prostate Cancer ◽  
Exercise Training ◽  
Training Program ◽  
Controlled Trial ◽  
Vigorous Physical Activity ◽  
Randomized Controlled ◽  
Exercise Training Program ◽  
Cluster Randomized

Background:The ENGAGE (efficacy of a referral and physical activity program for survivors of prostate cancer) study established that a clinician referral and 12-week exercise training program increased vigorous physical activity at 12 weeks among men with prostate cancer. Here, we report the 6- and 12-month outcomes.Methods:In this multicenter cluster randomized controlled trial, we compared a clinician referral and exercise training program to usual care. Discounted gym membership was offered to men in the intervention condition on completion of the 12-week exercise program. Self-reported physical activity at 6 and 12 months was the primary outcome. Quality of life, anxiety, and depressive symptoms were secondary outcomes.Results:A total of 147 men meeting eligibility criteria agreed to participate (54 intervention, 93 control). A positive interaction effect for vigorous physical activity was observed at 6 months, but not 12 months. No significant effects for the secondary outcomes were found.Conclusions:A clinician referral and community-based supervised and unsupervised exercise training program, along with discounted gym membership, had a positive short-term effect on vigorous physical activity levels, but did not improve quality of life, in men with prostate cancer.

scholarly journals Gene Expression Pathways in Prostate Tissue Associated with Vigorous Physical Activity in Prostate Cancer

2021 ◽  
pp. cebp.1461.2020
Author(s):  
Claire H Pernar ◽  
Giovanni Parmigiani ◽  
Edward L. Giovannucci ◽  
Eric B. Rimm ◽  
Svitlana Tyekucheva ◽  
...  
Keyword(s):  
Gene Expression ◽  
Physical Activity ◽  
Prostate Cancer ◽  
Vigorous Physical Activity ◽  
Prostate Tissue ◽  
Expression Pathways

scholarly journals Sedentary Patterns and Systemic Inflammation: Sex-Specific Links in Older Adults

2021 ◽  
Vol 12 ◽  
Author(s):  
Oscar Bergens ◽  
Andreas Nilsson ◽  
Konstantinos-Georgios Papaioannou ◽  
Fawzi Kadi
Keyword(s):  
Physical Activity ◽  
Older Adults ◽  
Sedentary Time ◽  
Inflammatory Marker ◽  
Vigorous Physical Activity ◽  
Older Men ◽  
Inflammatory Biomarkers ◽  
Low Grade ◽  
Linear Regression Models ◽  
Anti Inflammatory

The study aimed to examine sex-specific associations between objectively measured sedentary patterns and pro- and anti-inflammatory biomarkers in older adults when considering the moderating impact of physical activity (PA). Accelerometer-based monitoring of sedentary patterns and PA was conducted in a population of older men (n = 83; age: 67.4 ± 1.5; height: 178.7 ± 6.6 cm; weight: 80.9 ± 10.6 kg) and women (n = 146; age: 67.4 ± 1.6; height: 164.2 ± 6.1 cm; weight: 64.6 ± 10.1 kg) aged 65–70. Blood samples were collected for the assessment of the inflammatory biomarkers C-reactive protein (CRP), fibrinogen, interleukin-6 (IL-6), IL-10, IL-18, and monocyte chemoattractant protein-1 (MCP-1). Data were analyzed using multiple linear regression models. Total and bouts of ≥10 min of sedentary time were inversely associated with the anti-inflammatory marker IL-10 in older men (accumulated sedentary time: β = −0.116; bouts: β = −0.099; all p < 0.05). Associations were independent of moderate-to-vigorous physical activity (MVPA) and total PA volume. In women, total and bouts of ≥10 min of sedentary time were detrimentally associated with the pro-inflammatory marker fibrinogen (accumulated sedentary time: β = −0.130; bouts: β = −0.085; all p < 0.05). Associations remained between accumulated sedentary time and fibrinogen when adjusting for MVPA and total PA volume. This study highlights sex-specific routes by which sedentary patterns impact on pro- and anti-inflammatory biomarkers in older adults. The findings support efforts to promote accumulation of time spent in PA at the expense of time in sedentary pursuits on low-grade inflammation in older men and women.

scholarly journals Variability of Pain Outcomes and Physical Activity Among a Diverse Sample of Older Men: Is It More Than Just Race?

2019 ◽  
Vol 5 ◽  
pp. 233372141987858
Author(s):  
Tamara A. Baker ◽  
Elizabeth Vásquez ◽  
Jacquelyn A. Minahan
Keyword(s):  
Physical Activity ◽  
Physical Functioning ◽  
Vigorous Physical Activity ◽  
Panel Study ◽  
White Men ◽  
Well Being ◽  
Older Men ◽  
The United States ◽  
Number Of Factors ◽  
Pain Outcomes

There is a compendium of data documenting the increasing number of older adults. This suggests the continued need to understand identified health outcomes across domains of pain and physical activity, particularly among older men. Therefore, the aim of this study was to evaluate race similarities and/or differences in pain and rates of physical activity among White, Black, and Hispanic men 60+ years of age. Data were taken from the Health and Retirement Study, a longitudinal panel study surveying a representative sample of people in the United States. Logistic regression analysis was used to examine associations between race and pain and the odds of regular physical activity. Results showed that Black men were less likely to participate in light or moderate/vigorous physical activity. Similarly, pain increased the odds of physical activity among Hispanics, but decreased the odds of physical activity among White men. Findings may reflect a number of factors that impact the well-being of what it means to experience pain and physical functioning, while also assuming a masculine identity. This perspective may allow for a better understanding of short- and long-term implications of the pain experience and the pain and physical functioning dyad among this group of men.

scholarly journals Physical Activity and Prostate Cancer Mortality in Puerto Rican Men

2008 ◽  
Vol 5 (6) ◽  
pp. 918-929 ◽  
Author(s):  
Carlos J. Crespo ◽  
Mario R. Garcia-Palmieri ◽  
Ellen Smit ◽  
I-Min Lee ◽  
Daniel McGee ◽  
...  
Keyword(s):  
Physical Activity ◽  
Prostate Cancer ◽  
Puerto Rican ◽  
Cancer Mortality ◽  
Activity Index ◽  
Vigorous Physical Activity ◽  
Multivariate Logistic Regression Analysis ◽  
Rural Residence ◽  
Prostate Cancer Mortality ◽  
Urban Rural

Studies on the association between physical activity and fatal prostate cancer have produced inconclusive results. The Puerto Rico Heart Health Program was a cohort study of a randomly selected sample of 9824 men age 35 to 79 years at baseline who were followed for mortality until 2002. Multiple examinations collected information on lifestyle, diet, body composition, exercise, urban-rural residence, and smoking habits. Physical activity status was measured using the Framingham Physical Activity Index, an assessment of occupational, leisure-time, and other physical activities measured as usual activity over the course of a 24-hour day. Physical activity was strati-fed into quartiles. Multivariate logistic regression analysis was used to assess the association of physical activity with prostate cancer mortality. Other covariates included age, education, urban-rural residence, smoking, and body mass index. Compared with the lowest level of physical activity (Q1), the risk of prostate cancer mortality was OR = 0.99 (95% CI = 0.64–1.55) for Q2, OR = 1.34 (95% CI = 0.88–2.05) for Q3, and OR = 1.19 (95% CI = 0.75–1.90) for Q4. Further analyses by age group, overweight status, or vigorous physical activity also did not show a significant association between physical activity and prostate cancer mortality. Physical activity did not predict prostate cancer mortality in this group of Puerto Rican men.

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