scholarly journals Sedentary Patterns and Systemic Inflammation: Sex-Specific Links in Older Adults

2021 ◽  
Vol 12 ◽  
Author(s):  
Oscar Bergens ◽  
Andreas Nilsson ◽  
Konstantinos-Georgios Papaioannou ◽  
Fawzi Kadi
Keyword(s):  
Physical Activity ◽  
Older Adults ◽  
Sedentary Time ◽  
Inflammatory Marker ◽  
Vigorous Physical Activity ◽  
Older Men ◽  
Inflammatory Biomarkers ◽  
Low Grade ◽  
Linear Regression Models ◽  
Anti Inflammatory

The study aimed to examine sex-specific associations between objectively measured sedentary patterns and pro- and anti-inflammatory biomarkers in older adults when considering the moderating impact of physical activity (PA). Accelerometer-based monitoring of sedentary patterns and PA was conducted in a population of older men (n = 83; age: 67.4 ± 1.5; height: 178.7 ± 6.6 cm; weight: 80.9 ± 10.6 kg) and women (n = 146; age: 67.4 ± 1.6; height: 164.2 ± 6.1 cm; weight: 64.6 ± 10.1 kg) aged 65–70. Blood samples were collected for the assessment of the inflammatory biomarkers C-reactive protein (CRP), fibrinogen, interleukin-6 (IL-6), IL-10, IL-18, and monocyte chemoattractant protein-1 (MCP-1). Data were analyzed using multiple linear regression models. Total and bouts of ≥10 min of sedentary time were inversely associated with the anti-inflammatory marker IL-10 in older men (accumulated sedentary time: β = −0.116; bouts: β = −0.099; all p < 0.05). Associations were independent of moderate-to-vigorous physical activity (MVPA) and total PA volume. In women, total and bouts of ≥10 min of sedentary time were detrimentally associated with the pro-inflammatory marker fibrinogen (accumulated sedentary time: β = −0.130; bouts: β = −0.085; all p < 0.05). Associations remained between accumulated sedentary time and fibrinogen when adjusting for MVPA and total PA volume. This study highlights sex-specific routes by which sedentary patterns impact on pro- and anti-inflammatory biomarkers in older adults. The findings support efforts to promote accumulation of time spent in PA at the expense of time in sedentary pursuits on low-grade inflammation in older men and women.

Is Physical Activity-Related Self-Efficacy Associated with Moderate to Vigorous Physical Activity and Sedentary Behaviour among Ambulatory Children with Cerebral Palsy?

2021 ◽  
pp. e20200064
Author(s):  
Felipe Ganz ◽  
Virginia Wright ◽  
Patricia J. Manns ◽  
Lesley Pritchard
Keyword(s):  
Physical Activity ◽  
Sedentary Behaviour ◽  
Motor Function ◽  
Self Efficacy ◽  
Sedentary Time ◽  
Vigorous Physical Activity ◽  
Linear Regression Models ◽  
Gross Motor ◽  
Gross Motor Function ◽  
Gmfcs Level

Purpose: To determine how physical activity-related self-efficacy is associated with physical activity and sedentary behaviour time among ambulatory children with cerebral palsy (CP). Method: Children with CP, Gross Motor Function Classification System (GMFCS) Levels I-III ( N = 26; aged 9–18 y), completed the task self-efficacy component of a self-efficacy scale and wore Actigraph GT3X+ accelerometers for 5 days. Correlations (Pearson and Spearman’s rank-order; a = 0.050) were conducted to evaluate the relationships among age, GMFCS level, self-efficacy, and both daily moderate-to-vigorous physical activity (MVPA) and sedentary time. Linear regression models were used to determine the relationships among the independent variables and MVPA and sedentary time. Results: Self-efficacy was positively associated with MVPA time ( r = 0.428, p = 0.015) and negatively correlated with sedentary time ( r = –0.332, p = 0.049). In our linear regression models, gross motor function (β = –0.462, p = 0.006), age (β = –0.344, p = 0.033), and self-efficacy (β = 0.281, p = 0.080) were associated with MVPA time ( R2 = 0.508), while GMFCS level (β = 0.439, p = 0.003) and age (β = 0.605, p < 0.001) were associated with sedentary time ( R2 = 0.584). Conclusions: This research suggests that self-efficacy, age, and gross motor function are associated with MVPA in children with CP. Additional research is needed to confirm these findings and further explore the influence of self-efficacy on sedentary behaviour.

scholarly journals Changes in Objectively Measured Lifestyle Factors During the COVID-19 Pandemic in Community-Dwelling Older Adults

2021 ◽  
Author(s):  
Takuya Ataka ◽  
Noriyuki Kimura ◽  
Atsuko Eguchi ◽  
Etsuro Matsubara
Keyword(s):  
Physical Activity ◽  
Older Adults ◽  
Sedentary Time ◽  
Vigorous Physical Activity ◽  
Wearable Sensors ◽  
Lifestyle Factors ◽  
Community Dwelling ◽  
Activity Level ◽  
Objectively Measured ◽  
Community Dwelling Older Adults

Abstract Background: In this manuscript, we aimed at investigating whether objectively measured lifestyle factors, including walking steps, sedentary time, amount of unforced physical activity, level of slight and energetic physical activity, conversation time, and sleep parameters altered before and during the COVID-19 pandemic among community-dwelling older adults.Methods: Data were obtained from a prospective cohort study conducted from 2015 to 2019 and a subsequent dementia prevention study undertaken in September 2020. Community-dwelling adults aged ≥65 years wore wearable sensors before and during the pandemic.Results: A total of 56 adults were enrolled in this study. The mean age was 74.2±3.9 years, and 58.9% (n=33) of the participants were female. The moderate and vigorous physical activity time significantly decreased and sedentary time significantly increased during the pandemic. Conclusions: This is the first study to demonstrate differences in objectively assessed lifestyle factors before and during the COVID-19 pandemic among community-dwelling older adults. The findings show that the pandemic has adversely affected physical activity among older adults living on their own in Japan.

scholarly journals Physical Activity Intensity Cut-Points for Wrist-Worn GENEActiv in Older Adults

2021 ◽  
Vol 2 ◽  
Author(s):  
François Fraysse ◽  
Dannielle Post ◽  
Roger Eston ◽  
Daiki Kasai ◽  
Alex V. Rowlands ◽  
...  
Keyword(s):  
Physical Activity ◽  
Older Adults ◽  
Classification Accuracy ◽  
Operating Characteristic ◽  
Sedentary Time ◽  
Vigorous Physical Activity ◽  
Physical Activity Intensity ◽  
Characteristic Analysis ◽  
Free Living ◽  
Activity Intensity

Purpose: This study aims to (1) establish GENEActiv intensity cutpoints in older adults and (2) compare the classification accuracy between dominant (D) or non-dominant (ND) wrist, using both laboratory and free-living data.Methods: Thirty-one older adults participated in the study. They wore a GENEActiv Original on each wrist and performed nine activities of daily living. A portable gas analyzer was used to measure energy expenditure for each task. Testing was performed on two occasions separated by at least 8 days. Some of the same participants (n = 13) also wore one device on each wrist during 3 days of free-living. Receiver operating characteristic analysis was performed to establish the optimal cutpoints.Results: For sedentary time, both dominant and non-dominant wrist had excellent classification accuracy (sensitivity 0.99 and 0.97, respectively; specificity 0.91 and 0.86, respectively). For Moderate to Vigorous Physical Activity (MVPA), the non-dominant wrist device had better accuracy (ND sensitivity: 0.90, specificity 0.79; D sensitivity: 0.90, specificity 0.64). The corresponding cutpoints for sedentary-to-light were 255 and 375 g · min (epoch independent: 42.5 and 62.5 mg), and those for the light-to-moderate were 588 and 555 g · min (epoch-independent: 98.0 and 92.5 mg) for the non-dominant and dominant wrist, respectively. For free-living data, the dominant wrist device resulted in significantly more sedentary time and significantly less light and MVPA time compared to the non-dominant wrist.

scholarly journals Relationship between Physical Performance and Frailty Syndrome in Older Adults: The Mediating Role of Physical Activity, Sedentary Time and Body Composition

2020 ◽  
Vol 18 (1) ◽  
pp. 203
Author(s):  
Irene Rodríguez-Gómez ◽  
Asier Mañas ◽  
José Losa-Reyna ◽  
Luis M. Alegre ◽  
Leocadio Rodríguez-Mañas ◽  
...  
Keyword(s):  
Physical Activity ◽  
Older Adults ◽  
Body Composition ◽  
Physical Performance ◽  
Healthy Aging ◽  
Sedentary Time ◽  
Vigorous Physical Activity ◽  
Skeletal Muscle Index ◽  
The Relationship

The objectives were to clarify whether the relationship between physical performance and frailty was independently and jointly mediated by movement behaviors and body composition. We analyzed 871 older adults (476 women) from The Toledo Study for Healthy Aging. Skeletal muscle index (SMI) and fat index (FI) were determined using bone densitometry. Sedentary time (ST) and moderate-to-vigorous physical activity (MVPA) were assessed using accelerometry. The Frailty Trait Scale and The Short Physical Performance Battery (SPPB) were used to evaluate frailty and physical performance, respectively. Simple and multiple mediation analyses were carried out to determine the role of movement behaviors and body composition, adjusted for potential confounders. ST and MVPA acted independently as mediators in the relationship between SPPB and frailty (0.06% for ST and 16.89% for MVPA). FI also acted as an independent mediator in the same relationship (36.47%), while the mediation role of SMI was not significant. MVPA and FI both acted jointly as mediators in this previous relationship explaining 58.15% of the model. Our data support the fact that interventions should simultaneously encourage the promotion of MVPA and strategies to decrease the FI in order to prevent or treat frailty through physical performance improvement.

Risk for losing physical independence in older adults: The role of sedentary time, light, and moderate to vigorous physical activity

Maturitas ◽  
2014 ◽  
Vol 79 (1) ◽  
pp. 91-95 ◽  
Author(s):  
Elisa A. Marques ◽  
Fátima Baptista ◽  
Diana A. Santos ◽  
Analiza M. Silva ◽  
Jorge Mota ◽  
...  
Keyword(s):  
Physical Activity ◽  
Older Adults ◽  
Sedentary Time ◽  
Vigorous Physical Activity ◽  
Physical Independence

scholarly journals Sedentary Time in US Older Adults Associated With Disability in Activities of Daily Living Independent of Physical Activity

2015 ◽  
Vol 12 (1) ◽  
pp. 93-101 ◽  
Author(s):  
Dorothy D. Dunlop ◽  
Jing Song ◽  
Emily K. Arntson ◽  
Pamela A. Semanik ◽  
Jungwha Lee ◽  
...  
Keyword(s):  
Physical Activity ◽  
Older Adults ◽  
Activities Of Daily Living ◽  
Sedentary Behavior ◽  
Daily Living ◽  
Sedentary Time ◽  
Vigorous Physical Activity ◽  
Strong Relationship ◽  
Vigorous Activity ◽  
Adl Disability

Background:The harmful relationship of sedentary behavior to health may reflect an exchange of sedentary activity for moderateto- vigorous physical activity (MVPA), or sedentary behavior may be a separate risk factor. We examined whether time spent in sedentary behavior is related to disability in activities of daily living (ADL), independent of time spent in MVPA in older adults.Methods:The nationally representative 2003−2006 National Health and Nutrition Examinations Surveys (NHANES) included 2286 adults aged 60 years and older in whom physical activity was assessed by accelerometer. The association between ADL task disability and the daily percentage of sedentary time was evaluated by multiple logistic regression.Results:These adults on average spent 9h/d being sedentary during waking hours and 4.5% reported ADL disability. The odds of ADL disability were 46% greater (odds ratio, 1.46; 95% confidence interval, 1.07−1.98) for each daily hour spent in sedentary behavior, adjusted for MVPA and socioeconomic and health factors.Conclusion:These US national data show a strong relationship between greater time spent in sedentary behavior and the presence of ADL disability, independent of time spent in moderate or vigorous activity. These findings support programs encouraging older adults to decrease sedentary behavior regardless of their engagement in moderate or vigorous activity.

scholarly journals Duration or Timing? What is the Optimal Core for Older Adults to Engage in Moderate-to-vigorous Physical Activity to Prevent Disability?

2020 ◽  
Author(s):  
Ting-Fu Lai ◽  
Yung Liao ◽  
Chien-Yu Lin ◽  
Wan-Chi Huang ◽  
Ming-Chun Hsueh ◽  
...  
Keyword(s):  
Physical Activity ◽  
Older Adults ◽  
Physical Function ◽  
Gait Speed ◽  
Handgrip Strength ◽  
Vigorous Physical Activity ◽  
Total Duration ◽  
Functional Mobility ◽  
Linear Regression Models ◽  
Timed Up And Go

Abstract Background The positive association between the total duration of physical activity and performances of physical function may vary at different times of the day as circadian rhythm regulates individuals in response to external stimulations. We aimed to examine the association of timing-specific and overall moderate-to-vigorous physical activity (MVPA) with performances of physical function in older adults. Methods A cross-sectional analysis was conducted among 118 older adults (mean age = 70.0 ± 5.0 years). We assessed and identified timing-specific (morning: 06:01-12:00; afternoon: 12:01-18:00; evening: 18:01-24:00) and overall MVPA using a triaxial accelerometer. Different measures of physical function were evaluated including handgrip strength (by grip dynamometer), gait speed (five-meter walk test), basic functional mobility (timed up and go test), and lower limb strength (five times sit-to-stand test). Multivariate linear regression models adjusting for covariates were used to investigate the associations. Results Participants spent 0.4 hours in MVPA per day on average, half the time spent during the morning (47.7%), followed by during the afternoon (29.9%) and evening (21.6%). The time spent on overall MVPA was generally associated with better physical function performances. There was statistical evidence for the percentages of MVPA engagement during the morning ( B = 0.214, 95% confidence interval [CI] 0.001 to 0.428) and afternoon ( B = -0.273, 95% CI -0.518 to -0.027) associated with basic functional mobility but with contrary directions; the percentage of MVPA engagement during the evening was associated with less time spent in gait speed performance ( B = -0.237, 95% CI -0.468 to -0.006). Conclusions Our findings inform implications that the overall MVPA engagement was more important than timing-specific MVPA to older adults’ physical function performances. Strategies for accumulating time of MVPA is more practical and effective than encouraging to engage MVPA in specific timing for the enhancement of functional ability and therefore prevent disability among older adults.

scholarly journals Considerations in Processing Accelerometry Data to Explore Physical Activity and Sedentary Time in Older Adults

2020 ◽  
Vol 28 (4) ◽  
pp. 623-633
Author(s):  
Claire L. Cleland ◽  
Sara Ferguson ◽  
Paul McCrorie ◽  
Jasper Schipperijn ◽  
Geraint Ellis ◽  
...  
Keyword(s):  
Physical Activity ◽  
Older Adults ◽  
Sedentary Time ◽  
Vigorous Physical Activity ◽  
Low Frequency ◽  
Correlation Coefficients ◽  
Population Surveillance ◽  
Rank Test ◽  
Cut Points ◽  
The Impact

Processing decisions for accelerometry data can have important implications for outcome measures, yet little evidence exists exploring these in older adults. The aim of the current study was to investigate the impact of three potentially important criteria on older adults, physical activity, and sedentary time. Participants (n = 222: mean age 71.75 years [SD = 6.58], 57% male) wore ActiGraph GT3X+ for 7 days. Eight data processing combinations from three criteria were explored: low-frequency extension (on/off), nonwear time (90/120 min), and intensity cut points (moderate-to-vigorous physical activity ≥1,041 and >2,000 counts/min). Analyses included Wilcoxon signed-rank test, paired t tests, and correlation coefficients (significance, p < .05). Results for low-frequency extension on 90-min nonwear time and >1,041 counts/min showed significantly higher light and moderate-to-vigorous physical activity and lower sedentary time. Cut points had the greatest impact on physical activity and sedentary time. Processing criteria can significantly impact physical activity and/or sedentary time, potentially leading to data inaccuracies, preventing cross-study comparisons and influencing the accuracy of population surveillance.

scholarly journals Is adiposity associated with objectively measured physical activity and sedentary time in older adults?

2019 ◽  
Author(s):  
Wenfei Zhu ◽  
Zhiwei Cheng ◽  
Virginia J. Howard ◽  
Suzanne E. Judd ◽  
Steven N. Blair ◽  
...  
Keyword(s):  
Physical Activity ◽  
Older Adults ◽  
Racial Differences ◽  
White Women ◽  
Sedentary Time ◽  
Sedentary Behaviors ◽  
Linear Regression Models ◽  
Cross Sectional ◽  
Black And White ◽  
Objectively Measured

Abstract Background: Many older adults in the U.S. do not achieve the recommended amount of physical activity (PA) to fully realize a myriad of health benefits. Adiposity may be one of those important correlates of PA and sedentary behaviors. However, the full extent to which adiposity is associated with PA and sedentary time (SED) is uncertain. Therefore, we examined the association of adiposity with objectively measured PA and SED in black and white older adults. Methods: We conducted a cross-sectional study of older adults enrolled in the REasons for Geographic and Racial Differences in Stroke (REGARDS) Study 2003-2007 who participated in an ancillary accelerometer study 2009-2013. Assessment of body mass index (BMI) and waist circumference (WC) was completed during an in-home visit in the parent study. PA was measured by ActicalTM accelerometers, which provided estimates of moderate-to-vigorous-intensity PA (MVPA), light-intensity PA (LPA), and SED for 4-7 consecutive days. Data from accelerometers were standardized to square root percentages of total wear time per day (SqrtMVPA%, SqrtLPA%, and SqrtSED%). Interactions were tested for BMI and WC by race and sex, separately. Results: Data were available for 7,873 participants (69.8 ± 8.7 yr, 54.2% women, 31.5% African American). In mixed linear regression models, significant interactions existed in BMI by race and sex for the SqrtMVPA%, WC by race and sex for the SqrtMVPA% and the SqrtLPA% model(P<0.05). No interaction was significant for the logistic model of meeting the PA guideline or not. In subgroup analyses, BMI was inversely associated with SqrtMVPA%, SqrtLPA%, and positively related to SqrtSED% in black women, white men and white women after adjustments. Similar patterns were observed between WC and SqrtMVPA%, SqrtLPA%, and SqrtSED% in all groups, respectively. However, BMI was not associated with SqrtMVPA% in black men. Those with higher BMI or WC were less likely to meet the PA guideline in all groups. Conclusions: Adiposity was inversely associated with higher levels of MVPA/LPA and positively associated with higher levels of SED among black and white older adults. Prevention efforts aimed at promoting weight control may be beneficial to prevent physical inactivity and sedentary lifestyle among older adults.

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