scholarly journals The relationship of body mass index and serum testosterone with disease outcomes in men with castration-resistant metastatic prostate cancer

2008 ◽  
Vol 12 (1) ◽  
pp. 88-93 ◽  
Author(s):  
A J Armstrong ◽  
S Halabi ◽  
R de Wit ◽  
I F Tannock ◽  
M Eisenberger
Keyword(s):  
Prostate Cancer ◽  
Body Mass Index ◽  
Body Mass ◽  
Metastatic Prostate Cancer ◽  
Serum Testosterone ◽  
Castration Resistant ◽  
Disease Outcomes ◽  
Relationship Of ◽  
The Relationship

Prognostic role of body mass index (BMI) in patients with metastatic castration resistant prostate cancer (mCRPC) receiving chemotherapy: Preliminary results from a retrospective Italian multicenter study.

2016 ◽  
Vol 34 (2_suppl) ◽  
pp. 342-342
Author(s):  
Stefania Eufemia Lutrino ◽  
Caterina Fontanella ◽  
Orazio Caffo ◽  
Francesco Massari ◽  
Francesco Atzori ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Body Mass Index ◽  
Body Mass ◽  
Multicenter Study ◽  
Normal Weight ◽  
World Health ◽  
Castration Resistant Prostate Cancer ◽  
Castration Resistant ◽  
The Relationship ◽  
High Bmi

342 Background: Body mass index (BMI) is linked to an increased risk of cancers and a poorer prognosis. However, the evidence on the relationship between high BMI and metastatic castration resistant prostate cancer (mCRPC) is not entirely consistent and the data are conflicting. The aim of this observational, retrospective, multicenter study was to evaluate the correlation between BMI and progression-free survival (PFS) and overall survival (OS) in patients (pts) with mCRPC treated with chemotherapy. Methods: We collected mCRPC pts who received docetaxel 75 mg/m2 every 21 days as first line therapy in6 Italian Cancer Centers from 2005 to 2015. We classified BMI group according with the World Health Organization definition : normal weight BMI < 25kg/m2, overweight 25 ≤ BMI < 30kg/m2, and obese BMI ≥ 30kg/m2. Baseline characteristics and treatment information has been recorded in an anonymized excel file. Results: We collected 113 pts with a median age of 70.7 years (62 to 87) at the time of mCRPC diagnosis. In our cohort 33.6% of pts were normal weight at the HRPC diagnosis, 50.9% were overweight, and 15.5% were obese. At the baseline, 83.3% of obese pts had at least 1 co-morbidity versus 64.9% of normal/overweight pts. Moreover, 27.8% of obese pts needed a docetaxel dose reduction versus 17.5% normal/overweight pts. Only a non-significant trend for the detrimental effect of high BMI on PFS and OS has been documented. Median PFS in obese pts 6.4 months vs 7.0 months in of normal/overweight pts (p = 0.439); median OS in obese pts 38.8 months vs 43.4 months in of normal/overweight pts (p = 0.157). Conclusions: The relationship between BMI and mCRPC is extremely complex and unclear. Even if in this preliminary analysis we failed to confirm a significant association between BMI and survival, the data suggests that obesity may be associated with a lower tolerance to chemotherapy. Overall, we expected to enroll approximately 500 pts and data collection is currently ongoing.

The Relationship of Body Mass Index to Outcomes after Percutaneous Coronary Intervention

2006 ◽  
Vol 19 (5) ◽  
pp. 388-395 ◽  
Author(s):  
MAMDOUH M. SHUBAIR ◽  
POORNIMA PRABHAKARAN ◽  
VIKTORIA PAVLOVA ◽  
JAMES L. VELIANOU ◽  
ARYA M. SHARMA ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Percutaneous Coronary Intervention ◽  
Body Mass ◽  
Coronary Intervention ◽  
Percutaneous Coronary ◽  
Relationship Of ◽  
The Relationship

scholarly journals An Exploration of the Relationship of Body Mass Index with Motor Performance Measures and Quality of Life in Children Living in an Urban Setting

2016 ◽  
Vol 01 (04) ◽  
Author(s):  
John Fidler ◽  
Patrick McLaughlin ◽  
Deborah Bubela ◽  
Samantha E Scarneo ◽  
Jennifer McGarry ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Body Mass Index ◽  
Body Mass ◽  
Performance Measures ◽  
Motor Performance ◽  
Urban Setting ◽  
Relationship Of ◽  
The Relationship

scholarly journals The relationship of body mass index to penile length and testicular volume in adolescent boys

2012 ◽  
Vol 52 (5) ◽  
pp. 267
Author(s):  
Rizky Adriansyah ◽  
Muhammad Ali ◽  
Hakimi Hakimi ◽  
Melda Deliana ◽  
Siska Mayasari Lubis
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Junior High School ◽  
Testicular Volume ◽  
Adolescent Boys ◽  
Penile Length ◽  
School Students ◽  
Cross Sectional ◽  
Relationship Of ◽  
The Relationship

Background Evidence suggests that obesity may be related toearly onset of puberty in girls. However, few studies have found alink between body mass index (BMI) and puberty onset in boys.More study is needed to assess the relationship of BMI to penilelength and testicular volume.Objective To investigate the relationship ofBMI to penile lengthand testicular volume in adolescent boys.Methods A cross􀀿sectional study was carried out on adolescentboys aged 9 to 14 years in Secanggang District, Langkat Regency,North Sumatera Province in August 2009. Subjects' BMIs werecalculated by dividing body weight (BW) in kilograms by bodyheight (BH) in meters squared. Penile length (em) was measuredwith a spatula. We took the average of three measurements fromthe symphysis pubis to the tip of the glans penis. Testicular volume(mL) was estimated by palpation using an orchidometer. Pearson'scorrelation test (r) was used to assess the relationship of BMI topenile length and BMI to testicular volume.Resu lts There were 108 participants, consisting of 64primary school students and 44 junior high school students.Subjects' mean age was 11.7 (SO 1.62) years; mean BWwas 35.2 (SO 8.48) kg; mean BH was 1.4 (SO 0.11) m;mean BMI was 17.5 (SO 2.34) kg/m'; mean penile lengthwas 4.5 (SO 1.25) cm; and mean testicular volume was 3.6(SD 1.20) mL. We found no significant association betweenBMI and penile length (r􀀻-0.25, P􀀻0.06), nor betweenBMI and testicular volume (r􀀻-O.21; P􀀻O.09).Conclusion T here was no significant relationship ofBMI to penilelength nor BMI to testicular volume in adolescent boys.[Paediatr lndanes. 2012;52:267-71].

scholarly journals Body Mass Index and Its Change from Adolescence to Adulthood Are Closely Related to the Risk of Adult Metabolic Syndrome in China

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Bingyang Liu ◽  
Yue Li ◽  
Jiamei Guo ◽  
Yuting Fan ◽  
Ling Li ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Body Mass Index ◽  
Body Mass ◽  
Glycosylated Hemoglobin ◽  
Early Adulthood ◽  
Study Groups ◽  
Relationship Of ◽  
Baseline Bmi ◽  
The Relationship

Aims. To investigate the influence of body mass index (BMI) and its change from adolescence to adulthood (ΔBMI) on the risk of metabolic syndrome (MetS) in early adulthood. Methods. We selected 931 students from 12 to 16 years of age in Liaoyang City, China. Ninety-three participants from 18 to 22 years of age with complete baseline data were available for follow-up after 5 years. Statistical analysis determined the relationship of MetS at follow-up with baseline BMI (BMIb), ΔBMI, and follow-up BMI (BMIf). Results. ΔBMI was positively correlated with the change of waist circumference (ΔWC), systolic blood pressure (ΔSBP), triglycerides (ΔTG), uric acid, and glycosylated hemoglobin (ΔHbA1c) in follow-up ( p < 0.05 ). For every 1 kg/m2 increase in BMIb, ΔBMI, and BMIf, the risk of MetS at follow-up increased 1.201-fold, 1.406-fold, and 1.579-fold, respectively. Both BMIb and ΔBMI were predictive of MetS at follow-up, with prediction thresholds of 23.47 kg/m2 and 1.95 kg/m2. The participants were divided by the predicted BMIb and ΔBMI threshold values into four study groups. Interestingly, the group with lower BMI but a higher increase in BMI presented the same metabolic derangements and Mets% of the group with higher BMI but lower Δ BMI. Conclusion. Both BMI of adolescence and ΔBMI were predictive of MetS and cardiovascular risk factors in adulthood. Control of both variables in adolescents would be more effective in decreasing the risk of MetS in young adults than control of BMI alone.

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