Evaluation of chronic diarrhea and irritable bowel syndrome with diarrhea in adults in the era of precision medicine

2018 ◽  
Vol 113 (5) ◽  
pp. 660-669 ◽  
Author(s):  
Lawrence R. Schiller
Keyword(s):  
Irritable Bowel Syndrome ◽  
Precision Medicine ◽  
Chronic Diarrhea ◽  
Irritable Bowel

Benign Chronic Diarrhea of Infancy

1981 ◽  
Vol 3 (5) ◽  
pp. 153-158
Author(s):  
W. Allan Walker
Keyword(s):  
Irritable Bowel Syndrome ◽  
Chronic Diarrhea ◽  
Spontaneous Resolution ◽  
Gastrointestinal Problems ◽  
High Incidence ◽  
Bowel Movements ◽  
Separate Clinical Entity ◽  
Irritable Bowel ◽  
Classic Paper ◽  
Referral Practice

Chronic nonspecific diarrhea of infancy (CNSD) or irritable bowel syndrome represents one of the most common gastrointestinal problems confronted by practicing pediatricias. In the subspecialty setting of the pediatric gastroenterologist, this entity comprised almost 35% of the outpatient referral practice. CNSD, originally thought to be part of the celiac syndrome, was described as a separate clinical entity by Cohlan in 1956.1 Since that time in the classic paper on this subject, Davidson and Wasserman2 have described consistent diagnostic criteria further characterizing CNSD as a recognizable syndrome. The onset of symptoms occurs classically between 6 and 30 months of age with the development of three to six loose stools with mucous per day, with no associated malabsorption or growth and development abnormalities (to be discussed in detail below). Whereas spontaneous resolution of CNSD is anticipated by 39 months of age, longitudinal observations indicate that these patients have a high incidence of functional bowel complaints during adolescence and beyond suggesting a continuum with "irritable bowel syndrome" of adulthood.3 From the standpoint of the child, this "complaint" all too frequently becomes the "problem" when the frequency and/or consistency of the bowel movements impair training or become intolerable to the parents.

The pathogenic role of Blastocystis isolated from patients with irritable bowel syndrome and colitis from Iasi, Romania

2014 ◽  
Vol 60 (1) ◽  
Author(s):  
Doina S. Matiut ◽  
Lucian Hritcu
Keyword(s):  
Irritable Bowel Syndrome ◽  
Chronic Diarrhea ◽  
Clinical Manifestations ◽  
Total Serum ◽  
Pathogenic Potential ◽  
Ige Antibody ◽  
Etiologic Agents ◽  
Serum Iga ◽  
Irritable Bowel ◽  
Antibody Levels

AbstractBlastocystis is a common parasite and regarded as one of the etiologic agents of irritable bowel syndrome, colitis and chronic diarrhea. Our study was undertaken in order to identify different subtypes of Blastocystis isolated in patients with irritable bowel syndrome and colitis, as well as with chronic diarrhea and to evaluate their pathogenic potential. Seventy-three subjects (10 asymptomatic infected subjects, 49 subjects harboring Blastocystis or associated with other etiologic agents like bacteria, yeasts, protozoa, helminthes and 14 subjects with unknown etiologic agents) were investigated by in vitro parasitological and bacteriological stool samples followed by PCR subtyping of Blastocystis using STS primers, immunological markers (total serum IgA and IgE antibody levels), Helicobacter pylori antigen rapid test and fecal occult blood test. Also, among 49 subjects, there were 12 subjects harboring Blastocystis as the single etiologic agent. Subtyping proved that only three subtypes of Blastocystis were identified as following: subtype II (66.66%) in single infected subjects, subtype I (16.66%) in mixed infection with subtype II and subtype IV (8.33%) in single infected subjects. Total serum IgA and IgE antibody levels were in normal range. Subtype II was the most frequent subtype followed by subtype I and subtype IV of Blastocystis isolates in patients with irritable bowel syndrome, colitis, and chronic diarrhea as well as in asymptomatic infected group. Our results suggest that the severity of clinical manifestations depend on factors involving the host and possible parasitic density and not necessarily by isolated subtype.

scholarly journals CHRONIC DIARRHEA IN SOLDIERS; FACTS

2021 ◽  
Vol 71 (2) ◽  
pp. 638-41
Author(s):  
Muhammad Hafeez ◽  
Farrukh Saeed ◽  
Zafar Qureshi ◽  
Saad Ali Khan ◽  
Fuad Ahmad Siddiqi
Keyword(s):  
Irritable Bowel Syndrome ◽  
Chronic Diarrhea ◽  
Villous Atrophy ◽  
Military Hospital ◽  
Control Group ◽  
Control Groups ◽  
Duration Of Symptoms ◽  
Prospective Comparative Study ◽  
Irritable Bowel ◽  
And Control

Objective: To find out the underlying causes of chronic diarrhea in soldiers and how it differs from general population. Study Design: Prospective comparative study. Place and Duration of Study: Combined Military Hospital (CMH) Multan and Pak Emeritus Military Hospital (PEMH) Rawalpindi, from Dec 2017 to Jan 2020. Methodology: All soldiers in active service, having diarrhea more than 4 weeks in study and non-soldiers of the same age were included in the control group. There were inquired in details about the diarrhea symptoms and investigations carried out accordingly to find out the underlying cause. The two groups were compared to find out any differences. The data were analyzed by SPSS version 22. Results: Seventy one in study and 50 patients in control had their mean ages of 34.61 ± 8.35 and 32.42 ± 10.28 years. Mean duration of symptoms were 18 and 15 months in study and control groups respectively. Irritable Bowel Syndrome (IBS) was more common in both groups i.e. 14 (20%) and 20 (40%) in study and control groups respectively but frequency was more in second one. Seropositive celiac disease 13 (18.5%), seronegative villous atrophy 10 (14%) in study and Inflammatory Bowel Disease IBD 6 (12%) in control group were second most common conditions. Conclusions: Irritable bowel syndrome is common in this age group. Celiac and seronegative villous atrophy is second common conditions in the study group.

scholarly journals TREATMENT OF IRRITABLE BOWEL SYNDROME: A REVIEW

2018 ◽  
Vol 11 (9) ◽  
pp. 46
Author(s):  
Gupta Bikash ◽  
Dash Biswajit ◽  
Paul Sujata ◽  
Bora Jyoti Aditya
Keyword(s):  
Irritable Bowel Syndrome ◽  
Alternative Treatment ◽  
Chronic Diarrhea ◽  
Gastrointestinal Disease ◽  
Bulking Agents ◽  
Irritable Bowel ◽  
Pharmaceutical Agents ◽  
Specific Symptoms ◽  
Mucous Colitis

Irritable bowel syndrome (IBS) is a gastrointestinal disease which is also called as spastic colon, mucous colitis is characterized by some non-specific symptoms, such as altered bowel habits and abdominal pain, stomach bloating, chronic diarrhea or constipation or alternating between the two. The therapy is based on the healing of symptoms using various pharmaceutical and non-pharmaceutical agents. The objective of treatment is relief from symptom and improved quality of life. The approach for the treatment of IBS is based on the predominant symptoms of the patient. Classical as well as alternative treatment, both appear to be effective for the patients. Classical treatments basically consist of antidiarrheal, antidepressants, antispasmodic, bulking agents, osmotic laxatives, etc. Still, herbal or alternative treatment always seems to be the same beneficiary for the patients due to their negligible adverse effect.

Risk Factors for Chronic Diarrhea Not Related to Irritable Bowel Syndrome

2007 ◽  
Vol 102 ◽  
pp. S503-S504
Author(s):  
Joseph Y. Chang ◽  
Giles R. Locke ◽  
Cathy D. Schleck ◽  
Alan R. Zinsmeister ◽  
Nicholas J. Talley
Keyword(s):  
Risk Factors ◽  
Irritable Bowel Syndrome ◽  
Chronic Diarrhea ◽  
Irritable Bowel
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