Four years after implementation of a national micronutrient powder program in Kyrgyzstan, prevalence of iron deficiency and iron deficiency anemia is lower, but prevalence of vitamin A deficiency is higher

2018 ◽  
Vol 73 (3) ◽  
pp. 416-423 ◽  
Author(s):  
Elizabeth A. Lundeen ◽  
Jennifer N. Lind ◽  
Kristie E. N. Clarke ◽  
Nancy J. Aburto ◽  
Cholpon Imanalieva ◽  
...  
Nutrients ◽  
2018 ◽  
Vol 10 (10) ◽  
pp. 1483 ◽  
Author(s):  
James Wirth ◽  
Tamerlan Rajabov ◽  
Nicolai Petry ◽  
Bradley Woodruff ◽  
Nafisa Shafique ◽  
...  

Data on the nutritional situation and prevalence of micronutrient deficiencies in Azerbaijan are scarce, and knowledge about anemia risk factors is needed for national and regional policymakers. A nationally representative cross-sectional survey was conducted to assess the prevalence of micronutrient deficiencies, over- and undernutrition, and to disentangle determinants of anemia in children and women in Azerbaijan. The survey generated estimates of micronutrient deficiency and growth indicators for children aged 0–59 months of age (6–59 months for blood biomarkers) and non-pregnant women 15–49 years of age. Questionnaire data, anthropometric measurements, and blood samples were collected to assess the prevalence of under- and over-nutrition, anemia, iron deficiency, and iron deficiency anemia, in both groups. In children only, vitamin A deficiency and zinc deficiency were also assessed. In women only, folate and vitamin B12 deficiencies and vitamin A insufficiency were assessed. In total, 3926 household interviews were successfully completed with a response rate of 80.6%. In the 1455 children, infant and young child feeding practices were relatively poor overall; the prevalence of wasting and stunting were 3.1% and 18.0%, respectively; and 14.1% of children were overweight or obese. The prevalence of anemia was 24.2% in 6–59 months old children, the prevalence of iron deficiency was 15.0% in this age group, and the prevalence of iron deficiency anemia was 6.5%. Vitamin A deficiency was found in 8.0% of children, and zinc deficiency was found in 10.7%. Data from 3089 non-pregnant women 15–49 years of age showed that while undernutrition was scarce, 53% were overweight or obese, with increasing prevalence with increasing age. Anemia affected 38.2% of the women, iron deficiency 34.1% and iron deficiency anemia 23.8%. Vitamin A insufficiency was found in 10.5% of women. Folate and vitamin B12 deficiency were somewhat more common, with prevalence rates of 35.0% and 19.7%, respectively. The main risk factors for anemia in children were recent lower respiratory infection, inflammation and iron deficiency. In women, the main risk factors for anemia were iron deficiency and vitamin A insufficiency. Anemia is a public health problem in Azerbaijani children and women, and additional efforts are needed to reduce anemia in both groups.


Author(s):  
Arnab Biswas

Background: The objective of the study were to study the effect of the supplementation of vitamin A along with standard dose of iron on hematopoiesis in children with documented iron deficiency anemia, a hospital based prospective study is carried out for 6 months on children with documented iron deficiency anemia in OPD and indoor patients of the department of paediatric medicine, Medical College Kolkata..Methods: Thirty children (1-12 years age) presenting with iron deficiency anemia (hemoglobin less than 10 g/dl, mean corpuscular volume (MCV) <75 fl, and serum iron <55 mcg/dl) were studied in two groups of 15 each. Group I was supplemented with iron (ferrous sulphate 3 mg/kg/d) while group II in addition to iron was also supplemented with vitamin A (5000 IU/d).Collected data were expressed as mean±SE. Comparison of variables was done by using student t test or chi square test as applicable. P<0.0001 was taken as statistically significant.Results: Hemoglobin concentration was found to be significantly increased after 4 weeks of iron supplementation. Rise in hemoglobin was comparatively more in group II, as compared to group I, after 4 and 8 weeks.Conclusions: The result of this study suggests that supplementation of vitamin A improves hematopoiesis.


2020 ◽  
Vol 11 (1) ◽  
pp. 52-56
Author(s):  
Dwi Rahayu ◽  
Dono Indarto

Latar belakang: Anemia defisensi besi (ADB) merupakan salah satu masalah nutrisi pada remaja putri di seluruh dunia. Penyerapan zat besi di usus halus dipengaruhi oleh adanya vitamin C, kalsium, dan zink pada makanan. Penelitian ini bertujuan untuk mengetahui hubungan pola konsumsi vitamin A, vitamin C, kalsium dan zink terhadap kejadian ADB pada remaja putri. Metode: Penelitian ini merupakan penelitian case control yang melibatkan 60 remaja putri dengan ADB dan 58 remaja putri tanpa ADB. Diagnosis ADB berdasarkan kadar Hb dan indeks eritrosit, dan semikuantitatif FFQ digunakan untuk menentukan asupan vitamin dan mineral. Semua data dianalisis menggunakan test chi square dan tes regresi logistik ganda dengan p<0.05. Hasil: Semua subjek penelitian mempunyai asupan vitamin A dan C harian yang cukup tetapi asupan kalsium dan zinknya tergolong kurang (dalam mg). Namun, mereka semua memiliki frekuensi harian yang berbeda dalam mengkonsumsi mikronutrien tersebut. Remaja putri dengan asupan vitamin A yang jarang (OR=2.67; CI95%=1.10-6.50; p=0.03) dan asupan kalsium yang sering (OR=2.27; CI95%=0.85-6.03; p=0.10) lebih berisiko terkena ADB dibandingkan dengan remaja putri dengan asupan vitamin A yang sering dan asupan kalsium yang jarang. Akan tetapi hanya asupan vitamin A yang memiliki efek signifikan secara statistik. Kesimpulan: Hasil penelitian ini menunjukkan bahwa tingginya risiko ADB pada remaja putri berkaitan dengan asupan vitamin A yang jarang. Kata kunci: anemia defisiensi besi, asupan mikronutrien, remaja putri   Abstract Background: Iron deficiency anemia (IDA) is a nutritional problem that occurs in female adolescents around the world. Iron absorption in the small intestine is influenced by the presence of vitamin C, calcium, and zinc in ingested foods. This study aimed to investigate the relationship of vitamin A, vitamin C, calcium, and zinc intake with IDA in female adolescents. Methods: This case-control study was conducted in 60 anemic and 58 normal female adolescents. IDA diagnosis was determined using Hb levels and erythrocyte indexes and the semiquantitative food frequency questionnaire was used to determine vitamin and mineral intake. All collected data were analyzed using chisquare and multiple logistic regression tests with p<0.05. Results: All groups had an adequate intake of vitamin A and C but they had inadequate intake of calcium and zinc (in mg). However, they all had different frequencies in consuming those micronutrients. Rare intake of vitamin A (OR=2.67; CI95%=1.10-6.50; p=0.03) and frequent intake of calcium (OR=2.27; CI95%=0.85- 6.03; p=0.10) increased IDA, compared with frequent intake of vitamin A and rare intake of calcium but only vitamin A intake had a significant effect. Conclusion: Our findings suggest that a higher risk of IDA in female adolescents is related to a rare intake of vitamin A. Keywords: Iron deficiency anemia; micronutrient intake; female adolescents


2017 ◽  
Vol 16 (2) ◽  
pp. 90-95
Author(s):  
Rahayu Astuti ◽  
Hertanto Wahyu Subagyo ◽  
Siti Fatimah Muis ◽  
Budi Widianarko

2012 ◽  
Vol 2 (2) ◽  
pp. 180-90 ◽  
Author(s):  
B K Adhikari ◽  
U Koirala ◽  
STA Lama ◽  
P Dahal

Background Control of iron deficiency disorders is prioritized in the nutrition policies of Nepal. The situation is still threatening the public health in both rural and urban areas. Objective There are limited reviews on the iron deficiency situation in Nepal. This study was undertaken to find out the extent of iron deficiency anemia and intake of dietary iron among the general population in Nepal. Materials and methods Published research articles, books, bulletins, and online materials regarding iron deficiency were studied in both national and international scenarios. Results Nearly 46 percent of children (6–59 months) and 35 percent of women (15–49 years) were still suffering from anemia though the trend has been decreasing for the last 15 years. Mostly, young children (6–23 months) and pregnant women were the victims due to their high iron requirements and lower intake of dietary iron. The most common risk factors related to iron deficiency anemia (IDA) found in different studies were low intake of dietary iron, vitamin A deficiency, hookworm infection, malaria, heavy menstrual blood loss, and multiparity. Iron deficiency situation in the Nepalese population is triggered by Illiteracy, lack of awareness, negligence, poor economy, food insecurity, lack of food diversity, changes in dietary behavior, cultural behaviors, poor health and sanitation, and patriarchal structure of the society. Conclusion The main risk factor of IDA is low intake of dietary iron. There is a need of multiple approaches to address IDA with more focus on dietary iron to reduce anemia.DOI: http://dx.doi.org/10.3126/nje.v2i2.6573 Nepal Journal of Epidemiology 2012;2(2):182-190 


2021 ◽  
Vol 5 (1-1) ◽  
pp. 10-15
Author(s):  
Ali Sungkar

Nearly half of pregnant women in the world are reported to suffer anemia. And most of them are caused by iron deficiency, while the others by folate, vitamin B12 or vitamin A deficiency, chronic inflammation, parasite infections and hereditary disorders. Anemia in pregnant women is characterized when < 11 g / dL or any time during pregnancy. And when followed by low iron, it's called iron deficiency anemia. Iron plays an important role in many metabolic processes by transporting oxygen and allowing cells to generate energy. Low iron levels during pregnancy leading to anemia, related to an heightened risk of mother and fetus disease. Iron deficiency anemia can affect fetal development and persist long-term, while mild and serious pregnancy anemia can lead to premature birth, maternal and child mortality, bleeding, and infectious disease. The iron requirement during pregnancy exceeds 1000 mg for red cell expansion, 300 mg – 350 mg for developing fetus and placenta, and 250 mg for variable blood loss at delivery. Iron adequacy during pregnancy can be assured by proper nutrition, iron supplementation and fortification, and intravenous iron or blood transfusion. Iron supplementation is only enough to cover the prenatal iron requirements. Summary: Iron deficiency leading to anemia, rising risk of negative pregnancy outcomes. To meet increasing iron requirements during pregnancy including iron supplementation, fortification of staple iron foods, and intravenous iron or blood transfusion if required.


2022 ◽  
Vol 2022 ◽  
pp. 1-6
Author(s):  
Yan Ma ◽  
Yanbo Ma ◽  
Xiuqing Zhang ◽  
Xuejing Wang ◽  
Zhigang Sun

Objective. The purpose was to evaluate the treatment effect of iron proteinsuccinylate oral solution combined with vitamin A and D drops on children with nutritional iron deficiency anemia. Methods. 124 children treated in the outpatient department of our hospital from January 2017 to January 2020 were selected as the study subjects. They were randomly divided into control and observation two groups. The control group was treated with iron proteinsuccinylate oral solution (1.5 mL/kg) in the morning and evening, respectively. The observation group received adjuvant treatment with oral vitamin A and D drops based on the treatment of the control group. The treatment effect of proteinsuccinylate oral solution combined with vitamin A and D drops was evaluated by the serum iron (SI), serum ferritin (SF), and transferrin (TRF) levels, the values of CD3+, CD4+, and CD4+/CD8+, and other evaluation indicators. Results. After treatment, the SI and SF levels of children in both groups significantly increased ( P < 0.01 ) while the TRF level significantly decreased ( P < 0.01 ), and the SI and SF levels in the observation group increased more significantly, and the TRF level decreased more significantly compared with those in the control group ( P < 0.01 ). After treatment, the values of CD3+, CD4+, and CD4+/CD8+ of children in both groups significantly increased compared with those before treatment ( P < 0.01 ), and the values of CD3+, CD4+, and CD4+/CD8+ increased more significantly in the observation group compared with those in the control group ( P < 0.01 ). In addition, the evaluation results of treatment effect showed that the markedly effective rate in the observation group was significantly higher than that in the control group ( P < 0.01 ). Conclusion. Iron proteinsuccinylate oral solution combined with vitamin A and D drops can better improve the anemia symptoms in children, with high application value.


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