Influence of Fortified Tempe with Iron and Vitamin A to Increase Hemoglobin Level of Rats with Iron Deficiency Anemia

2017 ◽  
Vol 16 (2) ◽  
pp. 90-95
Author(s):  
Rahayu Astuti ◽  
Hertanto Wahyu Subagyo ◽  
Siti Fatimah Muis ◽  
Budi Widianarko
Keyword(s):  
Iron Deficiency ◽  
Vitamin A ◽  
Iron Deficiency Anemia ◽  
Hemoglobin Level ◽  
Deficiency Anemia

scholarly journals Iron Deficiency Anemia With a Life-Threatening Low Hemoglobin Level

Cureus ◽  
2021 ◽  
Author(s):  
Abdulrahman M Alateeq ◽  
Hessa A Alshammari ◽  
Abdulmalik M Alsaif
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Hemoglobin Level ◽  
Deficiency Anemia ◽  
Life Threatening

scholarly journals Edukasi Anemia Defisiensi Besi dan Pemeriksaan Hemoglobin sebagai Deteksi Dini Resiko pada Ibu Hamil di Desa Matang Seulimeng Kecamatan Langsa Barat Kota Langsa

2022 ◽  
Vol 1 (1) ◽  
pp. 114-121
Author(s):  
Dewita Dewita ◽  
Henniwati Henniwati ◽  
Lili Kartika Sari Hrp ◽  
Nora Veri
Keyword(s):  
Iron Deficiency ◽  
Early Detection ◽  
Pregnant Women ◽  
Community Service ◽  
Iron Deficiency Anemia ◽  
Hemoglobin Level ◽  
Economic Conditions ◽  
Deficiency Anemia ◽  
Questions And Answers ◽  
Three Stages

ABSTRAK  Anemia merupakan masalah global terutama bagi ibu hamil. Penyebab utama anemia pada kehamilan adalah defisiensi besi kemudian diikuti oleh defisiensi folat. WHO memperkirakan angka kejadian anemia sekitar 42 % terjadi pada ibu hamil dengan kondisi ekonomi menengah kebawah. Tujuan Pengabdian ini adalah untuk meningkatkan pengetahuan ibu hamil. tentang anemia defisensi besi dan pemeriksaan kadar hemoglobin sebagai deteksi dini mandiri di Desa Matang Seulimeng wilayah kerja Puskesmas Langsa Barat Kota Langsa. Bentuk kegiatan pengabdian masyarakat adalah dengan metode penyuluhan dengan ceramah dan tanya jawab. Sedangkan deteksi dini resiko tinggi dilakukan dengan pemeriksaan kadar hemoglobin dan setelah 2 minggu intervensi dilakukan evaluasi ibu hamil anemia dengan pemeriksaan kadar Hemoglobin. Terjadi perubahan peningkatan pengetahuan baik sebesar 85 % dan hasil pemeriksaan hemoglobin dari 18 ibu hamil anemia setelah evaluasi menjadi 67,8 %  tidak anemia .Penilaian mengenai pemahaman ibu hamil tentang edukasi anemia Defisiensi besi dan pemeriksaan Hemoglobin sebagai deteksi dini resiko pada ibu hamil adalah 3 (tiga) tahap (tahap pretest, tahap penyuluhan, dan tahap posttest serta evaluasi ibu hamil anemia). Adanya peningkatan pengetahuan setelah diberikan edukasi anemia defisiensi pada ibu hamil, dan mampu melakukan deteksi dini mandiri tanda gejala anemia sehingga mendapat penanganan sesegera mungkin. Kata Kunci : anemia defisiensi zat besi, kadar hemoglobin, deteksi dini, ibu hamil  ABSTRACT  Anemia is a global problem, especially for pregnant women. The main cause of anemia in pregnancy is iron deficiency followed by folate deficiency. WHO estimates that the incidence of anemia is around 42% in pregnant women with middle to lower economic conditions. The purpose of this service is to increase the knowledge of pregnant women. regarding iron deficiency anemia and hemoglobin level examination as an independent early detection in Matang Seulimeng Village, the working area of Langsa Barat Health Center, Langsa City. The form of community service activities is the extension method with lectures and questions and answers. Meanwhile, early detection of high risk is carried out by examining hemoglobin levels and after 2 weeks of intervention, pregnant women with anemia are evaluated by examining hemoglobin levels. There was an increase in knowledge of both 85% and the results of hemoglobin examination from 18 anemic pregnant women after the evaluation became 67.8% not anemic. An assessment of the understanding of pregnant women about iron deficiency anemia education and hemoglobin examination as early detection of risk in pregnant women is 3 (three) stages (pretest stage, counseling stage, and posttest stage and evaluation of anemic pregnant women). There is an increase in knowledge after being given education on deficiency anemia in pregnant women, and being able to independently detect early signs of anemia so that they get treatment as soon as possible. Keywords: iron deficiency anemia, hemoglobin levels, early detection, pregnant women

scholarly journals A COMPARATIVE STUDY OF INTRAVENOUS IRON SUCROSE VERSUS ORAL IRON THERAPY IN IRON DEFICIENCY ANEMIA DURING POSTPARTUM PERIOD

2021 ◽  
Vol 5 (12) ◽  
Author(s):  
Satish Kumar
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Serum Ferritin ◽  
Intravenous Iron ◽  
Hemoglobin Level ◽  
Oral Iron ◽  
Iron Sucrose ◽  
Deficiency Anemia ◽  
Iron Group ◽  
Iv Iron

Introduction: Anemia is the commonest major contributing factor in maternal mortality and morbidity in developing countries and according to World Health Organization (WHO) criteria, it contributes to 20% of maternal deaths. Anemia in pregnancy defined as hemoglobin level <11 gm/dl (7.45 mmol/L) and hematocrit less than 33% (WHO). Aim: To compare the efficacy of oral iron ferrous sulphate therapy with intravenous iron sucrose therapy in the treatment of iron deficiency anemia during postpartum period. Material & Methods: This was a prospective randomized comparative clinical trial single center study conducted on 200 postpartum women aged >18 years (after normal delivery or LSCS) within 10 days of delivery with Hb level more or equal to 6 gm/dl but less than 10 gm/dl were included in the study. This was a one year study conducted during 1st December 2018 to 30th November 2019. Results : There was a significant increase in the hemoglobin level in both the groups i.e. in IV iron group, from 8.26 ±1.03gm/dl on day 1 to 11.62±0.94gm/dl on day 45 as compared to oral iron group, from 8.24±1.09gm/dl on day 1 to 11.07±1.14gm/dl on day 45; and serum ferritin level from 41.69±40.45ng/ml on day 1 to 77.34±41.60ng/ml on day 45 in IV iron group as compared to the oral iron group from 22.20±8.82ng/ml on day 1 to 31.72±9.72 ng/ml on day 45. So, there was a rapid increase in both hemoglobin and serum ferritin levels in IV iron group as compared to the oral iron group. Conclusion: Intravenous iron sucrose administration increases the hemoglobin level and serum ferritin more rapidly in compare to the oral intake of ferrous sulphate in women with iron deficiency anemia in postpartum women in our study. Keywords: Iron deficiency anemia, Intravenous iron sucrose, Serum ferritin, Maternal mortality.

Immature Reticulocyte Fraction after Iron Therapy for Iron Deficiency Anemia.

Blood ◽  
2005 ◽  
Vol 106 (11) ◽  
pp. 3746-3746
Author(s):  
Young Jin Yuh ◽  
Sung Rok Kim ◽  
Tae Hee Han
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Fluorescence Intensity ◽  
Complete Blood Count ◽  
Reticulocyte Count ◽  
Hemoglobin Level ◽  
Iron Therapy ◽  
Deficiency Anemia ◽  
High Fluorescence ◽  
Lost To Follow Up

Abstract Background: Automated counting of reticulocyte introduced new reticulocyte parameters such as immature reticulocyte fraction(IRF). IRF is thought to be more sensitive than absolute or corrected reticulocyte count for detecting recovery of bone marrow function. The aim of this study is to assess the role of IRF for predicting the response of therapy after treatment of iron deficiency anemia. Methods: Patients with previously untreated iron deficiency anemia (blood hemoglobin &lt; 10.0g/dL and serum ferritin &lt; 10ng/mL) were enrolled into this study. On the 8th day of iron therapy, Complete blood count(CBC) with reticulocyte count and IRF was assessed by RAM-1 reticulocyte autoanalyzer(Sysmex. Tokyo, Japan). IRF was defined as sum of the reticulocyte fraction of high-fluorescence intensity regions plus the fraction of middle fluorescence intensity regions. After 1 month of iron therapy, CBC was reassessed to evaluate the response of iron therapy. The correlation of the 8th day IRF and the change of hemoglobin level after 4 weeks of therapy was evaluated. The 8th day corrected reticulcyte count was also evaluated. Results: From Jan. 2001 to May 2003, 27 patients with iron deficiency anemia (3 men and 24 women) entered into this study. We evaluated 21 patients, excluding 6 patients who were lost to follow-up or refused blood sampling after 1 month of iron therapy. The range of pretreatment hemoglobin level was 3.3–9.7g/dL (median 7.5/dL). The 8th day IRF was 0.06–0.39(median 0.15). Ten patients had the low IRF (IRF ≤ 0.15). Four of them (40%) had their hemoglobin level increased by more than 3g/dL. On the other side, 11 patients had high IRF (IRF &gt; 0.15) and 10 of them (91%) had their hemoglobin level increased by more than 3 g/dL. This difference was significant (P=0.024). However, the 8th day IRF was not correlated with the change of hemoglobin as strongly as the 8th day corrected reticulocyte count (Pearson coefficient 0.420 vs 0.693). Conclusion: For the patients with iron deficiency anemia, the 8th day of treatment IRF correlates with the response of iron treatment, but the 8th day of treatment corrected reticulocyte count has a stronger correlation.

Beneficiary effect of nanosizing ferric pyrophosphate as food fortificant in iron deficiency anemia: evaluation of bioavailability, toxicity and plasma biomarker

RSC Advances ◽  
2015 ◽  
Vol 5 (76) ◽  
pp. 61678-61687 ◽  
Author(s):  
Bindu Y. Srinivasu ◽  
Gopa Mitra ◽  
Monita Muralidharan ◽  
Deepsikha Srivastava ◽  
Jennifer Pinto ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Biological Response ◽  
Hemoglobin Level ◽  
Deficiency Anemia ◽  
Plasma Biomarker ◽  
Ferric Pyrophosphate ◽  
Iron Deficient ◽  
Plasma Proteomics

NP-Fe4(P2O7)3significantly improved hemoglobin level in iron-deficient rats and Fetuin-B showed differential biological response across NP doses through plasma proteomics.

scholarly journals Role of vitamin A supplementation in management of iron deficiency anemia in children

2018 ◽  
Vol 5 (4) ◽  
pp. 1477
Author(s):  
Arnab Biswas
Keyword(s):  
Iron Deficiency ◽  
Vitamin A ◽  
Iron Deficiency Anemia ◽  
Standard Dose ◽  
Ferrous Sulphate ◽  
Hemoglobin Concentration ◽  
Deficiency Anemia ◽  
Chi Square ◽  
Group I ◽  
Group Ii

Background: The objective of the study were to study the effect of the supplementation of vitamin A along with standard dose of iron on hematopoiesis in children with documented iron deficiency anemia, a hospital based prospective study is carried out for 6 months on children with documented iron deficiency anemia in OPD and indoor patients of the department of paediatric medicine, Medical College Kolkata..Methods: Thirty children (1-12 years age) presenting with iron deficiency anemia (hemoglobin less than 10 g/dl, mean corpuscular volume (MCV) <75 fl, and serum iron <55 mcg/dl) were studied in two groups of 15 each. Group I was supplemented with iron (ferrous sulphate 3 mg/kg/d) while group II in addition to iron was also supplemented with vitamin A (5000 IU/d).Collected data were expressed as mean±SE. Comparison of variables was done by using student t test or chi square test as applicable. P<0.0001 was taken as statistically significant.Results: Hemoglobin concentration was found to be significantly increased after 4 weeks of iron supplementation. Rise in hemoglobin was comparatively more in group II, as compared to group I, after 4 and 8 weeks.Conclusions: The result of this study suggests that supplementation of vitamin A improves hematopoiesis.

scholarly journals Does Normal Reticulocyte Hemoglobin Rule out Iron Deficiency As a Cause of Normocytic Normochromic Anemia?

Blood ◽  
2016 ◽  
Vol 128 (22) ◽  
pp. 4826-4826
Author(s):  
Zhou Yu ◽  
Leann Michelle Blankenship ◽  
Mohammed Ibrahim ◽  
Bolanle Gbadamosi ◽  
Michael Stender ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Conflicts Of Interest ◽  
Hemoglobin Level ◽  
Deficiency Anemia ◽  
Normocytic Anemia ◽  
Iron Store ◽  
Normocytic Normochromic Anemia ◽  
Normochromic Anemia ◽  
Rule Out

Abstract Background: Normochromic, normocytic anemia is the most frequently encountered type of anemia with a wide differential diagnosis. Iron studies are frequently ordered as part of the anemia work up as iron deficiency anemia could be potentially normocytic and normochromic. Recently reticulocyte hemoglobin has emerged as a marker to help identify early stages of iron deficiency at a time that other traditional biochemical studies for iron deficiency are non-informative. We hypothesize that normal reticulocyte hemoglobin level is a sensitive negative predictor of iron deficiency. Aim:To evaluate whether a normal reticulocyte hemoglobin level can be used to exclude iron deficiency anemia in patients with normocytic normochromic anemia. Methods:We reviewed the results of all hematological tests obtained as a part of hematopathology consults which were requested between January to April of 2016. Electronic medical records were screened for inclusion criteria. We included patient with hemoglobin less than 12g/dl, normal MCV (80-100) and normal reticulocyte hemoglobin level (>31 pg). We calculated the percentage of patients who had normal iron store suggested by ferritin, total iron binding capacity and iron saturation studies. Results:We included 41 patients who has normocytic normochromic anemia with normal reticulocyte hemoglobin level. 39 out of 41 patients have normal iron studies indicating iron deficiency anemia was not the cause of anemia. The overall negative predictive value is 95.1%. Among the two patients whose ferritin levels are mildly decreased, suggesting possible iron deficiency, one patient had a blood transfusion prior to checking reticulocyte hemoglobin level. The other patient donates blood frequently and was started on oral iron supplementation trial without any hemoglobin improvement after two weeks. It appeared that these two patients might not have true iron deficiency. Conclusion: Measurement reticulocyte hemoglobin level can serve as a useful marker to rule out iron deficiency as a cause of normocytic normochromic anemia. Serum Iron and ferritin studies are not indicated in patients with normocytic normochromic anemia with normal reticulocyte hemoglobin. Disclosures No relevant conflicts of interest to declare.

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