scholarly journals A qualitative investigation of the allergic rhinitis network from the perspective of the patient

2019 ◽  
Vol 29 (1) ◽  
Author(s):  
Biljana Cvetkovski ◽  
Vicky Kritikos ◽  
Rachel Tan ◽  
Kwok Yan ◽  
Elizabeth Azzi ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Health Care Professionals ◽  
Self Management ◽  
Over The Counter ◽  
Medication Prescription ◽  
Qualitative Exploration ◽  
Term Management ◽  
Selection Of

Abstract Patient self-selection of over-the-counter medicines for the management of allergic rhinitis is suboptimal. The mapping of the allergic rhinitis network demonstrates that patients’ decisions with regards to their allergic rhinitis management can be influenced by up to 11 individuals/resources (alters). This study aimed to identify the role of alters within the allergic rhinitis network and identify the factors that determined their degree of influence as perceived by the patient. This research was a qualitative exploration embedded in an empirical framework and social network theory. People with allergic rhinitis were interviewed about their network and transcripts were analysed deductively and inductively. Transcripts were coded by researchers independently and then discussed until agreement was reached. Forty-one participants described the roles of 17 alters on their allergic rhinitis management. The roles of alters fell within five categories: diagnosis, medication prescription/supply/administration, medication recommendation, information about allergic rhinitis and emotional support. Participant interactions with these alters were often acute and had a long standing effect, with the participants often navigating the long-term management on their own. The significance of the influence of each alter on their allergic rhinitis management was dependent on the level of trust in their relationship, impact of the role made to the participants’ day-to-day management of allergic rhinitis and/or the participant’s beliefs. Allergic rhinitis management was fragmented and had opportunity to be improved by developing strategies, resources and policies to support self-management in collaboration with patients and health-care professionals.

scholarly journals A Nonaligned Business World: The Global Socialist Enterprise between Self-Management and Transnational Capitalism

2020 ◽  
pp. 1-15
Author(s):  
Ljubica Spaskovska ◽  
Anna Calori
Keyword(s):  
Global Economy ◽  
Western Europe ◽  
Public Enterprise ◽  
Self Management ◽  
Soviet Bloc ◽  
Business World ◽  
Socialist Enterprise ◽  
Leading Role

Abstract This article explores the role of Yugoslav self-managed corporations in the global economy, with a particular attention to the late socialist period (1976–1991). Guided by a vision of a long-term integration of the Yugoslav economy into the international division of labor on the basis of equality and mutual interest, by the late 1970s the country’s foreign trade and hard currency revenue was boosted by a number of globally oriented corporate entities, some of which survived the demise of socialism and the dissolution of the country. These enterprises had a leading role as the country’s principal exporters and as the fulcrum of a web of economic contacts and exchanges between the Global South, Western Europe, and the Soviet Bloc. The article seeks to fill a historiographic gap by focusing on two major Yugoslav enterprises (Energoinvest and Pelagonija) that were based in the less-developed federal republics—Bosnia-Herzegovina and Macedonia. The article also investigates the transnational flow of ideas around the so-called “public enterprise,” its embeddedness in an interdependent global economy, and its visions for equitable development. Finally, the article explores these enterprises as enablers of social mobility and welfare, as well as spaces where issues of efficiency, planning, self-reliance, and self-management were negotiated.

Cytokines and Adhesion Molecules in Allergic Rhinitis

1998 ◽  
Vol 12 (1) ◽  
pp. 3-8 ◽  
Author(s):  
Claus Bachert ◽  
Martin Wagenmann ◽  
Gabriele Holtappels
Keyword(s):  
T Cells ◽  
Allergic Rhinitis ◽  
Adhesion Molecules ◽  
Current Knowledge ◽  
Allergic Inflammation ◽  
Allergen Challenge ◽  
Activated T Cells ◽  
Viral Rhinitis

This review summarizes our current knowledge of nasal allergic inflammation based on studies of cytokines, chemokines, and adhesion molecules in allergic rhinitis. The article also includes some aspects of viral rhinitis. Due to artificial or natural allergen exposure, an increase in the number of eosinophils and basophils, mast cells, IgE-positive cells, macrophages, monocyte-like cells, Langerhans cells, and activated T-cells can be observed within the mucosa and on the mucosal surface. Mediators are known to be released in response to allergens, but do not seem to be adequate to initiate the cell recruitment. After antigen challenge, the release of proinflammatory and regulatory cytokines could be demonstrated, and TH2-type cytokine mRNA upregulation in allergic mucosa has been shown. Proinflammatory cytokines initiate an adhesion cascade and activate T-cells that create an “atopic” cytokine environment within the tissue, which also may be linked to the long-term selective recruitment of eosinophils. However, the acute selective migration of eosinophils after allergen challenge is not fully understood, nor is the role of chemokines in allergic and viral rhinitis. Allergic rhinitis clearly represents an inflammatory reaction.

The role of clay, organic carbon and long-term management on mouldboard plough draught measured on the Broadbalk wheat experiment at Rothamsted

2006 ◽  
Vol 22 (4) ◽  
pp. 334-341 ◽  
Author(s):  
C. W. Watts ◽  
L. J. Clark ◽  
P. R. Poulton ◽  
D. S. Powlson ◽  
A. P. Whitmore
Keyword(s):  
Organic Carbon ◽  
Mouldboard Plough ◽  
Term Management

scholarly journals Understanding the role of the healthcare professional in patient self-management of allergic rhinitis

2015 ◽  
Vol 3 ◽  
pp. 205031211559582 ◽  
Author(s):  
Bonnie L Kuehl ◽  
Shahad Abdulnour ◽  
Michael O’Dell ◽  
Theodore K Kyle
Keyword(s):  
Allergic Rhinitis ◽  
Healthcare Professional ◽  
Self Management

The interrelation of the angiotensin and endothelin systems on the modulation of NAD(P)H oxidaseThis paper is one of a selection of papers published in this Special issue, entitled Young Investigator's Forum.

2006 ◽  
Vol 84 (1) ◽  
pp. 21-28 ◽  
Author(s):  
Marc-André Laplante ◽  
Jacques de Champlain
Keyword(s):  
Superoxide Anion ◽  
Nicotinamide Adenine Dinucleotide Phosphate ◽  
Cellular Membrane ◽  
Kinase C ◽  
Therapeutic Tools ◽  
Produce Superoxide Anion ◽  
Selection Of

The NAD(P)H oxidase is an enzyme assembled at the cellular membrane able to produce superoxide anion from NADH or NAD(P)H (nicotinamide adenine dinucleotide phosphate). It is one of the main sources of superoxide anion in cardiovascular tissues and its role in a variety of cardiovascular disorders such as atherosclerosis, cardiac hypertrophy, and endothelial dysfunction was recently proposed. Although, many factors and receptors were shown to lead to the activation of the enzyme, particulary the type 1 angiotensin receptor, the pathways involved are still widely unknown. Despite the identification of factors such as c-Src and protein kinase C implicated in the acute activation of NAD(P)H oxidase, the signalling involved in the sustained activation of the enzyme is probably far more complex than was previously envisioned. In this review, we describe the role of endothelin-1 in NAD(P)H oxidase signalling after a sustained stimulation by angiotensin II. Since most pathologies caused by an NAD(P)H oxidase overactivation develop over a relatively long period of time, it is necessary to better understand the long-term signalling of the enzyme for the development or use of more specific therapeutic tools.

scholarly journals Evolving ‘self’-management: exploring the role of social network typologies on individual long-term condition management

2015 ◽  
Vol 19 (5) ◽  
pp. 1044-1061 ◽  
Author(s):  
Rebecca L. Morris ◽  
Anne Kennedy ◽  
Caroline Sanders
Keyword(s):  
Social Network ◽  
Self Management ◽  
Term Condition

scholarly journals Painkillers among people aged 20-30 according to questionnaires

E-methodology ◽  
2021 ◽  
Vol 7 (7) ◽  
pp. 93-99
Author(s):  
KATARZYNA CIECIORA ◽  
ROKSANA PAPIERKOWSKA
Keyword(s):  
Real Problem ◽  
Age Group ◽  
Over The Counter ◽  
Know How ◽  
Wide Availability ◽  
Level Of Knowledge ◽  
Wide Access ◽  
Very High ◽  
Selection Of

Aim. Painkillers are one of the most widespread drugs on the pharmaceutical market, individual analgesics belong to the OTC (over-the-counter drug) group, which are also available outside pharmacies. The universality and wide availability of painkillers posea real problem of medication errors. The aim of the study was to examine the attitude of people aged 20-30 to taking painkillers and to examine the level of knowledge of the respondents about them.Method. The study involved 70 people aged 20-30 who voluntarily fi lled in an original electronic questionnaire, which included the attitude of people of this age to taking  medications and questions assessing their knowledge about the medications they take. It included questions about the type of drugs taken, frequency, intensity of pain at which the respondents took analgesics and knowledge about possible adverse effects in the case of long-term use of analgesics or their overdose. The most numerous age group were people aged 20-30, they constituted 55.7% of the respondents. People aged 24-27 accounted for 24.3%, while 20% were people aged 28-30. Most respondents showed that their current place of residence is a city with over 500,000 inhabitants. Most of the respondents had secondary education and it amounted to 51.4%.Results and conclusion. As many as 85.7% of people take painkillers. 35.7% of the respondents take medication once a month, while 34.3% take medication less frequently than once a month. 60.9% of people know the effects of chronic overuse of painkillers, butas many as 39.1% of respondents have a knowledge defi cit in this regard. The study found that 89.9% of people aged 20-30 know how to safely use painkillers, only 10.1% do not know in this regard. Most people in this age group use drugs when the intensity of pain is 4, which means that the most numerous group of people takes drugs when the intensity of pain is very high. This indicates that drugs are not taken without necessity, which results in their chronic non-use, as a result of which the risk of side effectscaused by overuse of painkillers is minimised. The study showed that 35.7% take painkillers once a month and 34.3% less than oncea month. Mostly women take medication once a month, this could possibly be associated with menstrual pain. The survey shows that 60.9% of people know the effects of chronic overuse of painkillers. It follows that most of the respondents know the consequences ofoverusing painkillers, but a large proportion of people in this age group show a defi cit of knowledge about what is dangerous to their health, therefore it is necessary to educate people aged 20-30 years in this regard.Cognitive value. The conducted research shows the attitude of young people toward painkillers. The cognitive value is the selection of a specifi c research group which from an early age, has the possibility to observe easy and wide access to analgesics.

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