scholarly journals Transcriptional landscape of epithelial and immune cell populations revealed through FACS-seq of healthy human skin

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Richard S. Ahn ◽  
Keyon Taravati ◽  
Kevin Lai ◽  
Kristina M. Lee ◽  
Joanne Nititham ◽  
...  
Biomolecules ◽  
2021 ◽  
Vol 12 (1) ◽  
pp. 11
Author(s):  
Alexa Corker ◽  
Lily S. Neff ◽  
Philip Broughton ◽  
Amy D. Bradshaw ◽  
Kristine Y. DeLeon-Pennell

During homeostasis, immune cells perform daily housekeeping functions to maintain heart health by acting as sentinels for tissue damage and foreign particles. Resident immune cells compose 5% of the cellular population in healthy human ventricular tissue. In response to injury, there is an increase in inflammation within the heart due to the influx of immune cells. Some of the most common immune cells recruited to the heart are macrophages, dendritic cells, neutrophils, and T-cells. In this review, we will discuss what is known about cardiac immune cell heterogeneity during homeostasis, how these cell populations change in response to a pathology such as myocardial infarction or pressure overload, and what stimuli are regulating these processes. In addition, we will summarize technologies used to evaluate cell heterogeneity in models of cardiovascular disease.


2013 ◽  
Vol 71 (2) ◽  
pp. 109-119 ◽  
Author(s):  
Catharina Bartmann ◽  
Sabine E. Segerer ◽  
Lorenz Rieger ◽  
Michaela Kapp ◽  
Marc Sütterlin ◽  
...  

Physiology ◽  
2001 ◽  
Vol 16 (1) ◽  
pp. 33-37 ◽  
Author(s):  
M. Schmelz ◽  
L. J. Petersen

The combination of vasodilation and protein extravasation following activation of nociceptors has been termed “neurogenic inflammation.” In contrast to rodents, no neurogenic protein extravasation can be elicited in healthy human skin. Dermal microdialysis has considerably increased our knowledge about neurogenic inflammation in human skin, including the involvement of mast cells.


2008 ◽  
Vol 38 (9) ◽  
pp. 2419-2425 ◽  
Author(s):  
Patrizia Castellani ◽  
Giovanna Angelini ◽  
Laura Delfino ◽  
Andrea Matucci ◽  
Anna Rubartelli

MethodsX ◽  
2018 ◽  
Vol 5 ◽  
pp. 1473-1483 ◽  
Author(s):  
Alex J. Wadley ◽  
Rhys G. Morgan ◽  
Kate J. Heesom ◽  
Paul S. Hole ◽  
Steven J. Coles

1992 ◽  
Vol 122 (6) ◽  
pp. 1219-1231 ◽  
Author(s):  
Shu-Cai Huang ◽  
Michael L. Misfeldt ◽  
Kevin L. Fritsche

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