scholarly journals Residential radon exposure and brain cancer: an ecological study in a radon prone area (Galicia, Spain)

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Alberto Ruano-Ravina ◽  
Nuria Aragonés ◽  
Karl T. Kelsey ◽  
Mónica Pérez-Ríos ◽  
María Piñeiro-Lamas ◽  
...  
2014 ◽  
Vol 90 (4) ◽  
pp. 299-305 ◽  
Author(s):  
Alberto Ruano-Ravina ◽  
Nuria Aragonés ◽  
Mónica Pérez-Ríos ◽  
Gonzalo López-Abente ◽  
Juan M. Barros-Dios

2014 ◽  
Vol 44 (4) ◽  
pp. 994-1001 ◽  
Author(s):  
María Torres-Durán ◽  
Alberto Ruano-Ravina ◽  
Isaura Parente-Lamelas ◽  
Virginia Leiro-Fernández ◽  
José Abal-Arca ◽  
...  

The aim of the study was to assess the effect of residential radon exposure on the risk of lung cancer in never-smokers and to ascertain if environmental tobacco smoke modifies the effect of residential radon.We designed a multicentre hospital-based case–control study in a radon-prone area (Galicia, Spain). All participants were never-smokers. Cases had an anatomopathologically confirmed primary lung cancer and controls were recruited from individuals undergoing minor, non-oncological surgery. Residential radon was measured using alpha track detectors.We included 521 individuals, 192 cases and 329 controls, 21% were males. We observed an odds ratio of 2.42 (95% CI 1.45–4.06) for individuals exposed to ≥200 Bq·m−3 compared with those exposed to <100 Bq·m−3. Environmental tobacco smoke exposure at home increased lung cancer risk in individuals with radon exposure >200 Bq·m−3. Individuals exposed to environmental tobacco smoke and to radon concentrations >200 Bq·m−3 had higher lung cancer risk than those exposed to lower radon concentrations and exposed to environmental tobacco smoke.Residential radon increases lung cancer risk in never-smokers. An association between residential radon exposure and environmental tobacco smoke on the risk of lung cancer might exist.


2021 ◽  
pp. 111372
Author(s):  
Alberto Ruano-Ravina ◽  
Leonor Varela Lema ◽  
Marta García Talavera ◽  
Montserrat García Gómez ◽  
Santiago González Muñoz ◽  
...  

2016 ◽  
Vol 93 (2) ◽  
pp. 222-230 ◽  
Author(s):  
Raquel Barbosa-Lorenzo ◽  
Alberto Ruano-Ravina ◽  
Rebeca Ramis ◽  
Nuria Aragonés ◽  
Karl T. Kelsey ◽  
...  

2017 ◽  
Vol 37 (3) ◽  
pp. 728-741 ◽  
Author(s):  
María Lorenzo-González ◽  
Alberto Ruano-Ravina ◽  
Joaquín Peón ◽  
María Piñeiro ◽  
Juan Miguel Barros-Dios

2008 ◽  
Vol 94 (3) ◽  
pp. 228-241 ◽  
Author(s):  
Richard E. Thompson ◽  
Donald F. Nelson ◽  
Joel H. Popkin ◽  
Zenaida Popkin

2001 ◽  
Vol 272 (1-3) ◽  
pp. 43-51 ◽  
Author(s):  
L Tomášek ◽  
E Kunz ◽  
T Müller ◽  
J Hůlka ◽  
A Heribanová ◽  
...  

2021 ◽  
Vol 39 (15_suppl) ◽  
pp. e20566-e20566
Author(s):  
Angeles Rodriguez Martinez ◽  
Alberto Ruano

e20566 Background: Residential radon is the second most important risk factor for lung cancer. We aim to asses the effect of residential radon exposure on the risk of SCLC in general population. Methods: A multicentric hospital-based case-control study was designed including 10 hospitals from Spain and Portugal. Incident cases with pathological diagnosis of SCLC were prospectively recruited. Controls consisted in patients undergoing non-complex surgery unrelated to tobacco consumption. All study participants were sent a radon detector. Results: A total of 375 cases and 902 controls were recruited. 24.5% of cases were women. The median age at diagnosis was 66 for cases. 6.4% of the cases were younger than 50 years. Tobacco consumption was higher in cases compared to controls. Residential radon concentrations were higher than 147 Bq/m3 in 161 SCLC cases (42.9%). Median residential radon concentration was also higher in SCLC cases compared to controls (152.5 Bq/m3 vs 142 Bq/m3). Those people exposed to more than 147 Bq/m3 and heavy smokers showed an OR of 72,62 (95%CI 17.95 - 499.41) compared to never-smokers with less than 50 Bq/m3. Conclusions: radon exposure seems to increase the risk of small cell lung cancer. There is a significant lung cancer risk departing from 148 Bq/m3 and there is also a linear dose-response pattern. Tobacco consumption may also produce an important effect modification for radon exposure. Those individuals exposed to high radon concentrations and heavy smokers can have a very high risk of this cancer type compared with their low exposed and never-smoking counterparts. It is necessary to increase radon awareness among citizens and administrations in order they can establish the necessary protective and mitigation measures against residential radon. Effect modification between residential radon exposure and tobacco consumption on the risk of small cell lung cancer.[Table: see text]


Sign in / Sign up

Export Citation Format

Share Document