Nonsense mutation in PMEL is associated with yellowish plumage colour phenotype in Japanese quail

The existence of a neurofilament-deficient mutant of Japanese quail was recently documented (Yamasaki, H., C. Itakura, and M. Mizutani. 1991. Acta Neuropathol. 82:427-434), but the genetic events leading to the neurofilament deficiency have yet to be determined. Our molecular biological analyses revealed that the expression of neurofilament-L (NF-L) gene was specifically repressed in neurons of this mutant. To search for mutation(s) responsible for the shutdown of this gene expression, we cloned and sequenced the NF-L genes in the wild-type and mutant quails. It is eventually found that the NF-L gene in the mutant includes a nonsense mutation at the deduced amino acid residue 114, indicating that the mutant is incapable of producing even a trace amount of polymerization-competent NF-L protein at any situation. The identification of this nonsense mutation provides us with a solid basis on which molecular mechanisms underlying the alteration in the neuronal cytoskeletal architecture in the mutant should be interpreted.

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GENETIC AND PHENOTYPIC CORRELATIONS OF BODY WEIGHT AND SHANK LENGTH WITH SOME EGG PRODUCTION-RELATED TRAITS IN TWO JAPANESE QUAIL GENOTYPES DIFFERING IN PLUMAGE COLOUR

Egyptian Poultry Science Journal ◽

10.21608/epsj.2014.5309 ◽

2014 ◽

Vol 34 (1) ◽

pp. 133-149 ◽

Cited By ~ 2

Author(s):

Bothaina Mahmoud ◽

Gihan Farahat ◽

Ensaf El-Full

Keyword(s):

Body Weight ◽

Japanese Quail ◽

Egg Production ◽

Plumage Colour ◽

Phenotypic Correlations ◽

Genetic And Phenotypic Correlations

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Mapping of plumage colour and blood protein loci on the microsatellite linkage map of the Japanese quail

Animal Genetics ◽

10.1111/j.1365-2052.2005.01335.x ◽

2005 ◽

Vol 36 (5) ◽

pp. 396-400 ◽

Cited By ~ 17

Author(s):

M. Miwa ◽

M. Inoue-Murayama ◽

B. B. Kayang ◽

A. Vignal ◽

F. Minvielle ◽

...

Keyword(s):

Linkage Map ◽

Japanese Quail ◽

Blood Protein ◽

Plumage Colour ◽

Microsatellite Linkage

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Inheritance of plumage colour in the F1 and test cross progeny of Japanese quail

Nigerian Journal of Animal Production ◽

10.51791/njap.v47i3.158 ◽

2020 ◽

Vol 47 (3) ◽

pp. 212-224

Author(s):

T. I. Adedoyin ◽

T. R. Fayeye ◽

O. J. Amao

Keyword(s):

Japanese Quail ◽

Plumage Colour ◽

Wild Type ◽

Phenotypic Effect ◽

Chi Square ◽

Type Allele ◽

Test Cross ◽

Dominant Phenotype ◽

Recessive Genes ◽

Test Cross Progeny

Recessive genes produced its phenotypic effect only when its allele is identical while the dominant ones produced its effect either with identical or dissimilar alleles. This study was conducted to determine the mode of inheritance of plumage colour in Japanese quail flock in Nigeria, using the Manchurian Gold (MG), Pharaoh (PH) and Panda White (PW) plumage types. All possible crosses were made among the three colour variants making a total of nine mating groups. A total number of 2,348 F1 chicks and 1,563 test cross progeny obtained from the incubated eggs were classified and counted by their down colour into observable plumage colour groups. The expected phenotypic ratios of the F1 and test cross progeny were computed based on the assumption that parents that were homozygous for a particular plumage colour breed true. The results revealed that the Pharaoh plumage quails carry the wild-type allele (Wb) in homozygous form or in heterozygous with the Panda White (wb) allele. The Manchurian gold plumage quails carry the Manchurian Gold-type allele (Wb+) in heterozygous with either Wb or wb. All the Panda White chicks were homozygous for the wb allele, which was recessive to both Wb and Wb+ alleles. The Chi-square results confirm the heterozygousity of the dominant phenotype in the test crosses. It can be concluded that inheritance of plumage colour is controlled by autosomal genes with dominant hierarchy of MG> PH> PW (Wb+ >Wb>wb).

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Endothelin receptor B2 (EDNRB2) is associated with the panda plumage colour mutation in Japanese quail

Animal Genetics ◽

10.1111/j.1365-2052.2007.01568.x ◽

2007 ◽

Vol 38 (2) ◽

pp. 103-108 ◽

Cited By ~ 33

Author(s):

M. Miwa ◽

M. Inoue-Murayama ◽

H. Aoki ◽

T. Kunisada ◽

T. Hiragaki ◽

...

Keyword(s):

Japanese Quail ◽

Plumage Colour ◽

Endothelin Receptor ◽

Colour Mutation

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The Quantitative Ultrastructure of the Heart Muscle of Japanese Quail by Hypergravitation, Hypodynamy and Combination

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100158480 ◽

1990 ◽

Vol 48 (3) ◽

pp. 188-189

Author(s):

Anton Bózner ◽

Mikuláš Gažo ◽

Jozef Dostál

Keyword(s):

Japanese Quail ◽

Heart Muscle ◽

Relative Size ◽

Combination Group ◽

Control Group ◽

Group V ◽

Group Iii ◽

Space Flights ◽

Group I ◽

Quantitative Ultrastructure

It is anticipated that Japanese quail /Coturnix coturnix japonica/ will provide animal proteins in long term space flights. Consequently this species of birds is of research interest of international space program INTERCOSMOS. In the year 1987 we reported on an experiment /2/ in which the effect of chronic acceleration of 2 G hypergravitation, the hypodynamy and the simultaneous effect of chronic acceleration and the location in the centre of the turntable of the centrifuge on the protein fractions in skeletal muscles was studied. The ultrastructure of the heart muscle was now in this experiments examined as well.Japanese quail cockerels, aged 48 days were exposed to 2 G hypergravitation /group IV/ in a 6,4 m diameter centrifuge, to hypodynamy /group III/ and their combination /group V/, respectively for 6 days / Fig.1/. The hypodynamy in group III was achieved by suspending the birds in jackets without contact the floor. The group II was located in the centre ofthe turntable of the centrifuge. The control group I. was kept under normal conditions. The quantitative ultrastructure of myocard was evaluated by the methods of Weibel/3/ - this enables to determine the number, relative size and volume of mitochondria volume of single mitochondria, defficiency of mitochondrial cristae and volume of myofibrils.

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