scholarly journals On the possibility of using temperature to aid in thyroid nodule investigation

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
C. P. Damião ◽  
J. R. G. Montero ◽  
M. B. H. Moran ◽  
R. A. da Cruz Filho ◽  
C. A. P. Fontes ◽  
...  
Keyword(s):  
Thyroid Nodule ◽  
Infrared Thermography ◽  
Thyroid Nodules ◽  
Subcutaneous Fat ◽  
Skin Surface ◽  
Malignant Tumours ◽  
Training Process ◽  
Artificial Intelligence Technique ◽  
Additional Information ◽  
Fat Thickness

AbstractThyroid nodules are common, and their investigation is very important to exclude the possibility of cancer. The increase in blood vessels of malignant tumours may be related to local temperature augmentation detectable on the skin surface. The objective of this paper is to evaluate the feasibility of Infrared Thermography for cancer identification. For this purpose, two studies were performed. One used numerical modelling to simulate regional metabolic temperature propagation to evaluate whether a nodule is perceptible on the skin surface. A second study considered thyroid nodule identification by using convolutional neural networks (CNNs). First, variations in nodular size and fat thickness were investigated, showing that the fat layer has an important role in regional heat transfer. In the second study, the training process achieved accuracy of 96% for in-sample and 95% for validation. In the testing phase, 92% accuracy, 100% precision and 80% recall were achieved. Thus, the presented studies suggest the feasibility of using Infrared Thermography with the CNN Artificial Intelligence technique as additional information in the investigation of thyroid nodules for patients without a very thick subcutaneous fat layer.

High-resolution thyroid nodule clinic: analysis of 1674 thyroid nodules

2014 ◽  
Author(s):  
Jose Carlos Fernandez-Garcia ◽  
Carmen Maria Cortes-Salazar ◽  
Isabel Mancha-Doblas ◽  
Francisco Tinahones
Keyword(s):  
High Resolution ◽  
Thyroid Nodule ◽  
Thyroid Nodules

Correlates of visceral and subcutaneous fat thickness in non-diabetic obese and morbidly obese patients

2014 ◽  
Author(s):  
Ozen Oz Gul ◽  
Murat Pekgoz ◽  
Sumeyye Gullulu ◽  
Soner Cander ◽  
Ahmet Tutuncu ◽  
...  
Keyword(s):  
Subcutaneous Fat ◽  
Morbidly Obese ◽  
Obese Patients ◽  
Subcutaneous Fat Thickness ◽  
Fat Thickness

The Use of Ultrasonic Measurements on Subcutaneous Fat Thickness in Breeding of Japanese Shorthorn Cattle

1988 ◽  
Vol 59 (4) ◽  
pp. 335-343
Author(s):  
Yoshitaka NAGAMINE ◽  
Takashi HAYASHI ◽  
Hiroshi SATO ◽  
Akira NISHIDA ◽  
Shigeki KOMATSU
Keyword(s):  
Subcutaneous Fat ◽  
Ultrasonic Measurements ◽  
Subcutaneous Fat Thickness ◽  
Fat Thickness

scholarly journals Choosing the best algorithm among five thyroid nodule ultrasound scores: from performance to cytology sparing—a single-center retrospective study in a large cohort

2021 ◽  
Author(s):  
Clotilde Sparano ◽  
Valentina Verdiani ◽  
Cinzia Pupilli ◽  
Giuliano Perigli ◽  
Benedetta Badii ◽  
...  
Keyword(s):  
Thyroid Nodule ◽  
Thyroid Nodules ◽  
Real Life ◽  
Scoring Systems ◽  
Diagnostic Procedures ◽  
Needle Aspiration ◽  
Common Disease ◽  
Single Center ◽  
Thyroid Microcarcinoma ◽  
Thyroid Malignancies

Abstract Objective Incidental diagnosis of thyroid nodules, and therefore of thyroid cancer, has definitely increased in recent years, but the mortality rate for thyroid malignancies remains very low. Within this landscape of overdiagnosis, several nodule ultrasound scores (NUS) have been proposed to reduce unnecessary diagnostic procedures. Our aim was to verify the suitability of five main NUS. Methods This single-center, retrospective, observational study analyzed a total number of 6474 valid cytologies. A full clinical and US description of the thyroid gland and nodules was performed. We retrospectively applied five available NUS: KTIRADS, ATA, AACE/ACE-AME, EUTIRADS, and ACRTIRADS. Thereafter, we calculated the sensitivity, specificity, PPV, and NPV, along with the number of possible fine-needle aspiration (FNA) sparing, according to each NUS algorithm and to clustering risk classes within three macro-groups (low, intermediate, and high risk). Results In a real-life setting of thyroid nodule management, available NUS scoring systems show good accuracy at ROC analysis (AUC up to 0.647) and higher NPV (up to 96%). The ability in FNA sparing ranges from 10 to 38% and reaches 44.2% of potential FNA economization in the low-risk macro-group. Considering our cohort, ACRTIRADS and AACE/ACE-AME scores provide the best compromise in terms of accuracy and spared cytology. Conclusions Despite several limitations, available NUS do appear to assist physicians in clinical practice. In the context of a common disease, such as thyroid nodules, higher accuracy and NPV are desirable NUS features. Further improvements in NUS sensitivity and specificity are attainable future goals to optimize nodule management. Key Points • Thyroid nodule ultrasound scores do assist clinicians in real practice. • Ultrasound scores reduce unnecessary diagnostic procedures, containing indolent thyroid microcarcinoma overdiagnosis. • The variable malignancy risk of the “indeterminate” category negatively influences score’s performance in real-life management of thyroid lesions.

scholarly journals Can sonographic features of microcalcification predict thyroid nodule malignancy? a prospective observational study

2021 ◽  
Vol 52 (1) ◽  
Author(s):  
Mehrdad Nabahati ◽  
Rahele Mehraeen ◽  
Zoleika Moazezi ◽  
Naser Ghaemian
Keyword(s):  
Thyroid Nodule ◽  
Roc Analysis ◽  
Thyroid Nodules ◽  
Area Under The Curve ◽  
Positive Association ◽  
Needle Aspiration ◽  
Northern Iran ◽  
Significant Positive Association ◽  
Irregular Margin ◽  
Benign Nodules

Abstract Background The aim of this study was to investigate the diagnostic accuracy of microcalcification, as well as its associated sonographic features, for prediction of thyroid nodule malignancy. We prospectively assessed the patients with thyroid nodule, who underwent ultrasound-guided fine-needle aspiration during 2017–2020 in Babol, northern Iran. The ultrasonographic characteristics of the nodules, as well as their cytological results, were recorded. We used regression analysis to evaluate the relation between sonographic findings and nodule malignancy. A receiver operator characteristics (ROC) analysis was also used to estimate the ability of ultrasound to predict the characteristic features of malignancy, as estimated by the area under the curve (AUC). Results Overall, 1129 thyroid nodules were finally included in the study, of which 452 (40%) had microcalcification. A significant positive association was found between nodule malignancy and microcalcification in both univariate (OR=3.626, 95% CI 2.258–5.822) and multivariable regression analyses (OR=1.878, 95% CI 1.095–3.219). In the nodules with microcalcification, significant positive relations were seen between malignancy and hypoechogenicity (OR=3.833, 95% CI 1.032–14.238), >5 microcalcification number (OR=3.045, 95% CI 1.328–6.982), irregular margin (OR=3.341, 95% CI 1.078–10.352), and lobulated margin (OR=5.727, 95% CI 1.934–16.959). The ROC analysis indicated that AUC for hypoechogenicity, >5 microcalcification number, irregular margin, and lobulated margin were 60%, 62%, 55%, and 60%, respectively, in predicting malignant thyroid nodules. Conclusion The findings indicated that microcalcification can be a potential predictor of thyroid nodule malignancy. Also, the presence of irregular or lobulated margins, multiple intranodular microcalcification (>5 microcalcifications), and/or hypoechogenicity can improve the ability of microcalcification in distinguishing malignant from benign nodules.

Estimation of the carcass composition of different cattle breeds and crosses from fatness measurements and visual assessments

1986 ◽  
Vol 106 (2) ◽  
pp. 223-237 ◽  
Author(s):  
A. J. Kempster ◽  
J. P. Chadwick ◽  
D. D. Charles
Keyword(s):  
Subcutaneous Fat ◽  
Visual Assessment ◽  
Carcass Composition ◽  
Beef Breed ◽  
Percentage Unit ◽  
Wide Range ◽  
Fat Thickness ◽  
Substantial Bias ◽  
Visual Assessments ◽  
Thickness Measurements

SUMMARYCarcass data for 1053 steers from the Meat and Livestock Commission's beef breed evaluation programme were used to examine the relative precision of alternative fatness assessments for predicting carcass lean percentage. The data were from four trials and comprised both dairy-bred and suckler-bred cattle by a wide range of sire breeds.A visual assessment of carcass subcutaneous fat content to the nearest percentage unit (SFe) was the single most precise predictor both overall (residual S.d. = 2·28) and within breed (residual S.d. = 2·05). Precision was improved by the addition in multiple regression of the percentage perinephric and retroperitoneal fat (KKCF) in carcass, a visual score of the degree of marbling in the m. longissimus and selected fat thickness measurements taken by calipers on cut surfaces (residual S.d. = 2·11 (overall) and 1·90 (within breed)).When the best overall equation was applied to the breed means, there was substantial bias (predicted – actual carcass lean percentage). Biases ranged from +2·5 (purebred Canadian Holstein and Luing) to – 1·3 (Limousin crosses).Breeds differed significantly in carcass lean content when compared at equal levels of fatness measurements. The differences depended both on the precision with which the measurements predicted carcass lean content and the observed differences in carcass composition that existed before adjustments to equal fatness were made.The robustness of prediction equations was examined by applying them to independent sets of data (a total of 334 carcasses) from four other trials involving steers, heifers, cows and young bulls. Equations were stable for cattle of the same breed, sex and similar levels of fatness but important bias was found between more extreme types of cattle.

Subcutaneous fat thickness at slaughter in castrated and non-castrated Santa Inês and Dorper lambs and its influence on meat and carcass quality

2021 ◽  
pp. 104694
Author(s):  
Francisco Fernandes Junior ◽  
Amanda de Freitas Pena ◽  
Fernando Augusto Grandis ◽  
Natalia Albieri Koritiaki ◽  
Fabíola Cristine de Almeida Rego ◽  
...  
Keyword(s):  
Subcutaneous Fat ◽  
Carcass Quality ◽  
Subcutaneous Fat Thickness ◽  
Fat Thickness ◽  
Santa Inês

Abdominal Laser Lipolysis Using a Microprocessor-Controlled Robotic Arm with Non-Contact Heating and Cooling

2021 ◽  
Author(s):  
Thomas Fiala
Keyword(s):  
Cooling System ◽  
Subcutaneous Fat ◽  
Treatment Protocol ◽  
Abdominal Fat ◽  
Abdominal Circumference ◽  
Ordinal Scale ◽  
Robotic Arm ◽  
Ultrasound Measurement ◽  
Fat Thickness ◽  
The Mean

Abstract Background A novel FDA-cleared device uses a 1064 nm laser to non-invasively induce apoptosis for lipolysis of subcutaneous abdominal fat while maintaining comfortable skin temperatures with a proprietary jet cooling system (eon ®, Dominion Aesthetic Technologies, Inc.; San Antonio, TX). A programmable articulated robotic arm moves the treatment head without any subject contact, maintaining an appropriate three-dimensional treatment path, compensating for patient movement. Objectives The goal of this prospective, single center, open-label study was to demonstrate the safety and effectiveness of this device for reducing subcutaneous abdominal fat using an updated power delivery curve. Methods Male and female subjects with Fitzpatrick skin types I-VI (N=26) were treated. Four abdominal zones up to 150 cm 2 each, customized in size and location for body habitus were treated. Each zone underwent a single 20-minute treatment session. Follow-up visits occurred after 6 and 12 weeks. Using a standardized protocol, ultrasound measurement of subcutaneous abdominal fat thickness, abdominal circumference, reported patient satisfaction and digital images were obtained. Results The mean treatment area was 378.5 cm 2. At Week 12, there was a 21.6% mean reduction in abdominal subcutaneous fat thickness and a 4.1-cm (1.6-inch) mean reduction in abdominal circumference. Most subjects (84.6%) were satisfied or very satisfied with their results. The mean pain score was 2.5 on an 11-point ordinal scale. There were no non-responders. Only two adverse events were noted: mild transient erythema (n=1, 3.8%) and localized subcutaneous firmness (n=1, 3.8%) which resolved without intervention within 12 weeks. Conclusions This contact-free device is safe and effective for reducing subcutaneous abdominal fat and represents an improvement on the prior treatment protocol.

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