scholarly journals Radiographic and clinical assessment of unidirectional porous hydroxyapatite to treat benign bone tumors

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Toshiyuki Kunisada ◽  
Joe Hasei ◽  
Tomohiro Fujiwara ◽  
Eiji Nakata ◽  
Suguru Yokoo ◽  
...  
Keyword(s):  
Bone Formation ◽  
Bone Tumors ◽  
Young Patients ◽  
Radiographic Findings ◽  
Porous Hydroxyapatite ◽  
Marrow Cavity ◽  
Benign Bone Tumors ◽  
Bone Marrow Cavity ◽  
Radiographic Changes

AbstractUnidirectional porous hydroxyapatite (UDPHAp) was developed as an excellent scaffold with unidirectional pores oriented in the horizontal direction with interpore connections. The purpose of this study was to assess radiographic changes and clinical outcomes and complications following UDPHAp implantation to treat benign bone tumors. We retrospectively analyzed 44 patients treated with intralesional resection and UDPHAp implantation for benign bone tumors between 2010 and 2015. Clinical and radiographic findings were evaluated postoperatively at regular follow-up visits. The mean follow-up was 49 months. Radiographic changes were classified into five stages based on bone formation in the implanted UDPHAp according to Tamai’s classification. All patients showed excellent bone formation inside and around implanted UDPHAp. Absorption of UDPHAp and bone marrow cavity remodeling was identified in 20 patients at a mean of 17 months postoperatively, and was significantly more common in young patients. Preoperative cortical thinning was completely regenerated in 26 of 31 patients on average 10 months after surgery. There were no cases of delayed wound healing, postoperative infection, or allergic reaction related to implanted UDPHAp. UDPHAp is a useful bone-filling substitute for treating benign bone tumor, and the use of this material has a low complication rate.

scholarly journals Complications of Computer Tomography Assisted Radiofrequency Ablation in the Treatment of Osteoid Osteoma

2019 ◽  
Vol 2019 ◽  
pp. 1-6 ◽  
Author(s):  
Yunus Oc ◽  
Bekir Eray Kilinc ◽  
Sahin Cennet ◽  
Mehmet Metin Boyacioglu ◽  
Rodi Ertugrul ◽  
...  
Keyword(s):  
Radiofrequency Ablation ◽  
Osteoid Osteoma ◽  
Bone Tumors ◽  
Skin Infection ◽  
Primary Bone Tumors ◽  
Benign Bone Tumors ◽  
Superficial Skin ◽  
Primary Bone ◽  
A Prospective Study

Background. Osteoid osteoma (OO) is one of the most commonly occurring benign bone tumors. It constitutes 10-12% of benign bone tumors and 2-3% of primary bone tumors. In radiofrequency ablation (RFA) treatment, the cells of the tumor are thermally inactivated by the help of electrodes shaped like needles. In our study, we aimed to show the major and minor complications in patients undergoing RFA and to show what should be done to prevent these complications. Methods. The study was carried out as a prospective study on the follow-up of 87 osteoid osteoma patients treated between 2015 and 2017. The youngest of the patients was 1 year old and the oldest was 42 years old. The RFA procedure lasted 10 min on average, excluding anesthesia and preparation. All lesions were ablated at 90 degrees for 7 minutes with the heat increased gradually. All patients were followed up for 1 day in the orthopedics clinic. Results. Complications were observed in 7 patients. The lesions with the most complications were observed to be in the tibia, second-degree burns were seen in 2 patients, and superficial skin infection was observed in 2 patients. In 1 patient, the probe tip was broken and remained within the bone. Intramuscular hematoma was detected in 1 lesion located in the proximal femur. A complaint of numbness in the fingers developed in a lesion located in the metacarpus. Conclusion. Preventive measures should be taken before the procedure in order to prevent minor complications, and, for major complications, close follow-up should be done after the procedure and patients should be kept away from heavy physical activities for the first 3 months.

scholarly journals Renal adenocarcinoma associated with hypertrophic osteopathy in a cat

2020 ◽  
Vol 6 (2) ◽  
pp. 205511692096243
Author(s):  
Sarah Elhamiani Khatat ◽  
Rosario Vallefuoco ◽  
Meryem El Mrini ◽  
Morgane Canonne-Guibert ◽  
Dan Rosenberg
Keyword(s):  
Abdominal Mass ◽  
New Bone Formation ◽  
Abdominal Ultrasonography ◽  
Radiographic Findings ◽  
Renal Adenocarcinoma ◽  
First Case ◽  
Primary Neoplasm ◽  
The Right ◽  
Radiographic Changes

Case summary A 10-year-old neutered male domestic shorthair cat was diagnosed with renal adenocarcinoma associated with hypertrophic osteopathy. The cat was referred for chronic ambulation difficulties. The physical examination showed a painful thickening of all four limbs, a right cranial abdominal mass and a conjunctival hyperaemia. Radiographic findings were consistent with extensive periosteal new bone formation involving not only the diaphyses of the fore- and hindlimbs, but also of the pelvis, tarsus and carpus. Abdominal ultrasonography and CT revealed a mass within the right kidney and a primary neoplasm was suspected. A ureteronephrectomy of the right kidney was performed and histopathology confirmed the diagnosis of renal adenocarcinoma. Although clinical improvement of the lameness occurred after surgery, no radiographic changes of hypertrophic osteopathy lesions were observed at the 9-month follow-up. Relevance and novel information Feline cases of hypertrophic osteopathy are rarely reported in the literature and only a few of them were associated with abdominal neoplastic diseases. To our knowledge, this is the first case of renal adenocarcinoma associated with hypertrophic osteopathy in a cat.

Novel Unidirectional Porous β-Tricalcium Phosphate Used as a Bone Substitute after Excision of Benign Bone Tumors of the Hand: A Case Series

2018 ◽  
Vol 23 (03) ◽  
pp. 424-429 ◽  
Author(s):  
Akira Ikumi ◽  
Toru Funayama ◽  
Toshinori Tsukanishi ◽  
Hiroshi Noguchi ◽  
Masashi Yamazaki
Keyword(s):  
Bone Formation ◽  
Tricalcium Phosphate ◽  
Bone Substitute ◽  
Bone Tumors ◽  
Animal Studies ◽  
Case Series ◽  
Clinical Results ◽  
Benign Bone Tumors ◽  
Tumors Of The Hand ◽  
Satisfactory Clinical Result

Unidirectional porous β-tricalcium phosphate (UDPTCP; Affinos®, Kuraray, Tokyo, Japan) has been in clinical use since 2015. Animal studies have confirmed the excellent potential of UDPTCP with regard to bone formation and material absorption. We present the first three clinical cases using UDPTCP as a bone substitute after curettage of benign bone tumors of the hand. All three patients were males, 29-, 30- and 81-years-old, two having a diagnosis of enchondroma and the other, a bone ganglion, with a pathological fracture identified in one case. Over a mean follow-up of 10 months, all patients achieved satisfactory clinical result, with no adverse events of UDPTCP noted. Radiographic evidence of good bone formation and material absorption was observable over the postoperative course. UDPTCP provided satisfactory clinical results, with good biocompatibility and fast resorption characteristics. Therefore, UDPTCP could provide a safe and reliable filling substitute for bone defects following curettage of small bone tumors.

Expression of bone sialoprotein mRNA during bone formation and resorption induced by colchicine in rat tibial bone marrow cavity

2009 ◽  
Vol 10 (8) ◽  
pp. 1209-1217 ◽  
Author(s):  
N. Arai ◽  
K. Ohya ◽  
S. Kasugai ◽  
H. Shimokawa ◽  
S. Ohida ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Bone Formation ◽  
Bone Sialoprotein ◽  
Marrow Cavity ◽  
Tibial Bone ◽  
Bone Marrow Cavity

scholarly journals Rare Osteochondroma of the Posterior Talar Process: A Case Report

2020 ◽  
Author(s):  
Luan Pham ◽  
Daniel Wu
Keyword(s):  
Case Report ◽  
Bone Tumors ◽  
Surgical Excision ◽  
Current Understanding ◽  
Pathology Report ◽  
Cartilage Formation ◽  
Benign Bone Tumors ◽  
Healthy Female

Osteochondromas are benign bone tumors that arise from divergent cartilage formation most commonly in childhood versus adulthood. We report the case of a 42-year-old healthy female who presented with a unusual solitary posterolateral ankle mass with associated pain and ankle impingement with 6 weeks follow up. The patient was successfully treated with open surgical excision with bone with pathology diagnosis of benign osteochondroma. The patient returned to normal baseline function with no pain at 6 weeks follow up. Open posterior ankle incision approach performed to remove suspicious enlarged bony growth from posterior talar process sent to pathology. Pathology report returned benign osteochondroma of the posterior talar process and patient subsequently had routine healing of post op incision site and return to full function without pain or disability at 6 weeks follow up. This case study adds to the current understanding, incidence, occurrence, and treatment of rare osteochondromas occurring in the posterior talar process.

Talar Osteochondroma Fracture Presenting as Posterior Ankle Impingement

2016 ◽  
Vol 106 (3) ◽  
pp. 225-228 ◽  
Author(s):  
Ersin Ercin ◽  
Mustafa Gokhan Bilgili ◽  
Mehmet Gamsizkan ◽  
Serdar Avsar
Keyword(s):  
Differential Diagnosis ◽  
Bone Tumors ◽  
Surgical Intervention ◽  
Rare Condition ◽  
Histologic Examination ◽  
Posterior Aspect ◽  
Benign Bone Tumors ◽  
Ankle Impingement ◽  
Posterior Ankle Impingement

Osteochondromas are the most common benign bone tumors. They are usually asymptomatic and found incidentally. When symptomatic, the symptoms are usually due to its location and size. Fracture of an osteochondroma presenting as posterior ankle impingement is a rare condition. We describe a 22-year-old man with solitary exostosis who presented with a posterior ankle mass and posterior ankle impingement with 2 years of follow-up. Surgical intervention was the treatment of choice in this patient, and histologic examination revealed a benign osteochondroma. Osteochondromas found in the posterior aspect of the talus can be complicated by fracture due to persistent motion of the ankle. Talar osteochondroma should be included in the differential diagnosis of posterior ankle impingement causes. Posterior talar osteochondromas, especially when a stalk is present, should be treated surgically before it is more complicated by a fracture and posterior ankle impingement.

scholarly journals Spinal Osteoid Osteoma and scoliosis: who is the painful?

2019 ◽  
pp. 18-19
Keyword(s):  
Computed Tomography ◽  
Back Pain ◽  
Surgical Resection ◽  
Osteoid Osteoma ◽  
Bone Tumors ◽  
Young Patients ◽  
Lumbar Vertebra ◽  
Pathological Examination ◽  
X Ray ◽  
Benign Bone Tumors

Ten-year-old girl was referred to our clinic for back pain and stiffness of the spine. X-ray of the spine showed a dorsal scoliosis with no other abnormality (figure 1a). Computed Tomography (CT) showed the nidus in right pedicle of the 3rd lumbar vertebra (figure 1b). The diagnosis of Osteoid osteoma was retained and confirmed after surgical resection and pathological examination. Osteoid osteoma (O.O) accounts for 10 % to 20 % of benign bone tumors [1]. Up to 25% of all O.O are found in the spine. Two thirds of spinal O.O manifest as painful scoliosis [2]. The diagnosis of the tumor is usually delayed because easily missed on standard X-ray investigation. Systematic CT or MRI with dynamic contrast would be recommended for young patients presenting with painful scoliosis [3].

A Case Control Study of Cemented Acetabular Total Hip Arthroplasty Components in Patients Less than 50 with 5-Year Minimum Follow-up

2017 ◽  
Vol 27 (2) ◽  
pp. 122-127
Author(s):  
Thomas F.M. Yeoman ◽  
William Smy ◽  
Paul Gaston
Keyword(s):  
Patient Outcomes ◽  
Older Patients ◽  
Current Trend ◽  
Young Patients ◽  
Consecutive Series ◽  
Worst Case ◽  
Radiographic Findings ◽  
Total Hip ◽  
Significant Difference

Background This study investigates the outcomes of cemented sockets in young patients (<50 years) requiring a total hip replacement (THR) compared to older patients (>50 years) having the same procedure, under the same surgeon between June 2005 and May 2009. Methods Prosthesis survivorship rates, patient outcomes and radiological findings were compared between a consecutive series of 56 young patients (mean 42, range 25-49) and 56 older patients (mean 69, range 53-81) that underwent a primary THR using a cemented Stryker® Exeter™ Contemporary™ flanged cup. The minimum follow-up was 5 years. Results No significant difference was observed between the groups’ Oxford Hip Scores (p = 0.078) or satisfaction scores (p = 0.67). Worst case scenario analysis for revision, failure or lost to follow-up showed 94.6% survival in the <50 year olds and 92.9% survival in the >50 year olds at 5 years. This study demonstrates no significant difference in patient outcomes, survivorship or radiographic findings at a minimum of 5 years between patients <50 years old and those >50 years old undergoing THR with a cemented socket. Conclusions We believe the current trend towards uncemented cups may be driven by marketing rather than by evidence of improved outcomes. Cemented sockets provide very good outcomes for patients of all ages.

scholarly journals Chondromas and multiple enchondromatosis

2021 ◽  
Vol 27 (4) ◽  
pp. 441-445
Author(s):  
P. Lascombes ◽  
◽  
L. Mainard-Simard ◽  
◽  
Keyword(s):  
Surgical Treatment ◽  
Bone Tumors ◽  
Benign Tumor ◽  
Clinical Presentation ◽  
Radiological Findings ◽  
Benign Bone Tumors ◽  
Multiple Enchondromatosis ◽  
Pathologic Fractures ◽  
Bone Deformities

Introduction The chondromas are a cartilaginous proliferation of mature appearance and moderate size, reason why these tumors are regarded more like hamartomas than real benign tumor. Chondromas represent 10 to 12 % of benign bone tumors. Any bone of an enchondral ossification may be involved. Several bones can be involved, and the disease is called “chondromatosis”. In the review we describe clinical and radiological findings of this pathology as well as indications for reconstructive surgery. Material and methods The review is dedicated to isolated chondromas, periosteal and extraskeletal chondromas, chondromatosis. Results The aspects of epidemiology, clinical presentation, radiology, MRI, prognosis, indications and methods of surgical treatment have been described in the article for each types of chondroma and enchondromatosis. Conclusion Chondromas are benign bone tumors which may be responsible of pathologic fractures. Their surgical treatment consists in curettage and bone grafting or bone-cement filling with or without osteosynthesis. Multiple enchondromatosis should be considered as an osteochondrodysplasia. Its treatment is not the treatment of the multiple chondromas themselves, but of the bone deformities and length discrepancy induced by the disorder. The transformation of some tumors in chondrosarcomas in adolescence or adulthood needs a strict follow up of these patients.

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