scholarly journals Spatial distribution and determinants of thyroid cancer incidence from 1999 to 2013 in Korea

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Jieun Jang ◽  
Dae-Sung Yoo ◽  
Byung Chul Chun
Keyword(s):  
Thyroid Cancer ◽  
Cancer Screening ◽  
Cancer Incidence ◽  
Thyroid Dysfunction ◽  
Scan Statistics ◽  
Cancer Center ◽  
Spatial Clusters ◽  
Heavy Smoking ◽  
Thyroid Cancer Screening ◽  
Thyroid Cancer Incidence

AbstractWe evaluated the spatial variation in thyroid cancer incidence and its determinants in Korea considering its importance in cancer prevention and control. This study was based on the ecological design with cancer incidence data by administrative district from the National Cancer Center and regional characteristics generated from the Korea Community Health Survey Data. We identified spatial clusters of thyroid cancer incidences based on spatial scan statistics. Determinants of regional variation in thyroid cancer incidence were assessed using the Besag-York-Mollie model with integrated nested Laplace approximations. Spatial clusters for low and high thyroid cancer incidences were detected in the northeastern and southwestern regions, respectively. Regional variations in thyroid cancer incidence can be attributed to the prevalence of recipients of basic livelihood security (coefficient, − 1.59; 95% credible interval [CI], − 2.51 to − 0.67), high household income (coefficient, 0.53; 95% CI, 0.31 to 0.76), heavy smoking (coefficient, − 0.91; 95% CI, − 1.59 to − 0.23), thyroid dysfunction (coefficient, 3.24; 95% CI, 1.47 to 5.00), and thyroid cancer screening (coefficient, 0.38; 95% CI, 0.09 to 0.67). This study presented the spatial variations in thyroid cancer incidence, which can be explained by the prevalence of socioeconomic factors, thyroid cancer screening, thyroid dysfunction, and smoking.

scholarly journals Randomization to Screening for Prostate, Lung, Colorectal and Ovarian Cancers and Thyroid Cancer Incidence in Two Large Cancer Screening Trials

PLoS ONE ◽  
2014 ◽  
Vol 9 (9) ◽  
pp. e106880 ◽  
Author(s):  
Thomas J. O'Grady ◽  
Cari M. Kitahara ◽  
A. Gregory DiRienzo ◽  
Francis P. Boscoe ◽  
Margaret A. Gates
Keyword(s):  
Thyroid Cancer ◽  
Cancer Screening ◽  
Cancer Incidence ◽  
Ovarian Cancers ◽  
Thyroid Cancer Incidence ◽  
Screening Trials

scholarly journals Ambient air pollution exposure and thyroid cancer incidence in Iran

2021 ◽  
Author(s):  
Samaneh Dehghani ◽  
Arefe Abedinzade ◽  
Mohebat Vali
Keyword(s):  
Air Pollution ◽  
Thyroid Cancer ◽  
Cancer Incidence ◽  
Ambient Air ◽  
Ambient Air Pollution ◽  
Ozone Pollution ◽  
Annual Percent Change ◽  
Female Population ◽  
Percent Change ◽  
Thyroid Cancer Incidence

Introduction: Thyroid cancer is the most common endocrine malignant that is three times more prevalent in women than men. Fine particulate matter (PM2.5) has been indicated to affect Thyroid Hormone (TH) homeostasis. We sought to estimate the association between long-term exposure to ambient air pollution and the incidence of thyroid cancer in the Iranian female population. Materials and methods: We extracted thyroid cancer incidence and ambient air pollution data from Iran from 2000 to 2019 for males and females for all age groups from the Global Burden of Disease (GBD) dataset. We entered the data into Joinpoint to present Annual Percent Change (APC) and Average Annual Percent Change (AAPC) and its confidence intervals. We entered the information into R3.5.0. Results: Thyroid cancer in females had an upward trend [AAPC=4.9% (4.2-5.6)]. There was a correlation between ambient PM pollution (p≤0.001, r=0.84) and ambient ozone pollution (p≤0.001, r=0.94), and the incidence of thyroid cancer in females. The results of the analysis also showed a significant relationship between thyroid cancer incidence in females and secondhand  smoke (p≤0.001, r=0.74). Conclusion: This study indicated increasing trends in thyroid cancer incidence with exposure to ambient air pollution. Our novel findings provide additional insight into the potential associations between risk factors and thyroid cancer and warrant further investigation, specifically in areas with high levels of air pollution both nationally and internationally. However, causal relationships cannot be fully supported via ecological studies, and this article only focuses on Iran.

scholarly journals An Ethical Issue After the Nuclear Accident in Fukushima: Young People’S Perspectives of Thyroid Cancer Screening and its Harms

2021 ◽  
Author(s):  
Sanae Midorikawa ◽  
Akira Ohtsuru
Keyword(s):  
Thyroid Cancer ◽  
Cancer Screening ◽  
Young People ◽  
Ethical Issue ◽  
Screening Program ◽  
Nuclear Accident ◽  
School Based ◽  
Cancer Screening Program ◽  
Opt Out ◽  
Thyroid Cancer Screening

Abstract Background Overdiagnosis of thyroid cancer has become a major global medical issue. Ultrasound-based thyroid cancer screening has promoted overdiagnosis, and recently international recommendations indicate that such screening should not be conducted, even after a nuclear accident. The Fukushima thyroid cancer screening program was initiated in 2011 as a health policy after the nuclear accident, although the risk for radiation-induced thyroid cancer was unlikely given the low radiation levels. However, the thyroid cancer screening program has continued at 2-year intervals with a relatively high participation rate and is now in its fifth round. Therefore, it is crucial to clarify whether those targeted for screening understand the disadvantages of screening and identify factors that influenced their decision to participate. Methods We conducted an anonymous mail-based questionnaire that included young people from Fukushima (subjects) and a neighboring prefecture that was not targeted for screening (non-subjects). We asked them about the significance of the thyroid cancer screening in Fukushima, the reasons for taking or not taking a screening, their perception of the harms of screening, and their opinions on thyroid examination at school. Then we compared the results of the questionnaire between subjects and non-subjects and examinees (who accepted screening) and non-examinees (who declined screening). Results Only 16.5% of respondents were aware of the harms associated with thyroid cancer screening, with most perceiving that the benefits outweighed the harms. Comparison of subjects’ and non-subjects’ responses showed there were no significant differences between subjects and non-subjects. In addition, among subjects, there were no differences of responses between examinees and non-examinees. The most common reason for participation in screening was that the screening was conducted in schools and perceived as obligatory. Conclusions These results highlighted a serious ethical issue in that school-based screening leads to making young people think that it is mandatory screening in an opt-out and default setting manner, with a lack of knowledge about the disadvantages of screening. Based on the autonomy of the subjects and the ethical principle of the post-disaster, surveys after a nuclear disaster should be conducted in an opt-in style without an opt-out style such as school-based screening.

Sign in / Sign up

Export Citation Format

Share Document