scholarly journals Ambient air pollution exposure and thyroid cancer incidence in Iran

Author(s):  
Samaneh Dehghani ◽  
Arefe Abedinzade ◽  
Mohebat Vali

Introduction: Thyroid cancer is the most common endocrine malignant that is three times more prevalent in women than men. Fine particulate matter (PM2.5) has been indicated to affect Thyroid Hormone (TH) homeostasis. We sought to estimate the association between long-term exposure to ambient air pollution and the incidence of thyroid cancer in the Iranian female population. Materials and methods: We extracted thyroid cancer incidence and ambient air pollution data from Iran from 2000 to 2019 for males and females for all age groups from the Global Burden of Disease (GBD) dataset. We entered the data into Joinpoint to present Annual Percent Change (APC) and Average Annual Percent Change (AAPC) and its confidence intervals. We entered the information into R3.5.0. Results: Thyroid cancer in females had an upward trend [AAPC=4.9% (4.2-5.6)]. There was a correlation between ambient PM pollution (p≤0.001, r=0.84) and ambient ozone pollution (p≤0.001, r=0.94), and the incidence of thyroid cancer in females. The results of the analysis also showed a significant relationship between thyroid cancer incidence in females and secondhand  smoke (p≤0.001, r=0.74). Conclusion: This study indicated increasing trends in thyroid cancer incidence with exposure to ambient air pollution. Our novel findings provide additional insight into the potential associations between risk factors and thyroid cancer and warrant further investigation, specifically in areas with high levels of air pollution both nationally and internationally. However, causal relationships cannot be fully supported via ecological studies, and this article only focuses on Iran.

2016 ◽  
Vol 2016 (1) ◽  
Author(s):  
Marie Pedersen* ◽  
Massimo Stafoggia ◽  
Johan Sommar ◽  
Bente Oftedal ◽  
Andrei Pyko ◽  
...  

The Lancet ◽  
2015 ◽  
Vol 386 ◽  
pp. S5 ◽  
Author(s):  
Yuming Guo ◽  
Hongmei Zeng ◽  
Rongshou Zheng ◽  
Shanshan Li ◽  
Adrian G Barnett ◽  
...  

Author(s):  
Evanthia Giannoula ◽  
Christos Melidis ◽  
Savvas Frangos ◽  
Nikitas Papadopoulos ◽  
Georgia Koutsouki ◽  
...  

Over the last few decades, thyroid cancer incidence has had a significant increase. Despite well-known genetic and epigenetic factors (radiation, overdiagnosis, already existing benign thyroid tumors), the effect of air pollution on its incidence and mortality has not yet been fully elucidated. In this study, air pollution data from 27 EU member states is used in order to analyze its association with thyroid cancer incidence, and mortality and socioeconomic factors are examined as confounders. This ecological study used age standardized thyroid cancer incidence and mortality rates per 100,000 people for the year 2012 from 27 EU member states, collected from the International Agency for Research on Cancer, World Health Organization and European Cancer. Data regarding mean air pollutant mass concentrations for 1992, 2002 and 2012 was collected from the European Environment Agency. Data analysis was carried out using Prism 5.0 and SPSS v.20. Multiple regression analysis showed a statistically significant positive association between thyroid cancer incidence in men and the environmental 2012 masse of Benzo (k) Fluoranthene (r2 = 0.2142, p = 0.042) and HexaChlorocycloHexane (r2 = 0.9993, p = 0.0166). Additionally, a statistically significant positive association was observed between the thyroid cancer mortality rate in men and the 1992 environmental concentrations of Hg (r2 = 0.1704, p = 0.043). Data indicates that some air pollutants may have an effect on increased thyroid cancer incidence and mortality, at least in men. However, causal relationships cannot be fully supported via ecological studies, and this article only focuses on the EU and uses only three distinct time periods.


2016 ◽  
Vol 2016 (1) ◽  
Author(s):  
Marie Pedersen* ◽  
Zorana J Andersen ◽  
Mette Sørensen ◽  
Andrea Jaensch ◽  
Fulvio Ricceri ◽  
...  

2017 ◽  
Vol 154 ◽  
pp. 226-233 ◽  
Author(s):  
Marie Pedersen ◽  
Zorana J. Andersen ◽  
Massimo Stafoggia ◽  
Gudrun Weinmayr ◽  
Claudia Galassi ◽  
...  

2016 ◽  
Vol 144 ◽  
pp. 60-65 ◽  
Author(s):  
Yuming Guo ◽  
Hongmei Zeng ◽  
Rongshou Zheng ◽  
Shanshan Li ◽  
Adrian G. Barnett ◽  
...  

2021 ◽  
Vol 2021 (1) ◽  
Author(s):  
Jie Chen ◽  
Maciej Strak ◽  
Sophia Rodopoulou ◽  
Kees De Hoogh ◽  
Zorana J. Andersen ◽  
...  

2018 ◽  
Vol 4 (1) ◽  
pp. 113-120 ◽  
Author(s):  
Marie Pedersen ◽  
Massimo Stafoggia ◽  
Gudrun Weinmayr ◽  
Zorana J. Andersen ◽  
Claudia Galassi ◽  
...  

2018 ◽  
Vol 24 (1) ◽  
Author(s):  
V. S. CHAUHAN ◽  
BHANUMATI SINGH ◽  
SHREE GANESH ◽  
JAMSHED ZAIDI

Studies on air pollution in large cities of India showed that ambient air pollution concentrations are at such levels where serious health effects are possible. This paper presents overview on the status of air quality index (AQI) of Jhansi city by using multivariate statistical techniques. This base line data can help governmental and non-governmental organizations for the management of air pollution.


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