scholarly journals Transcriptome profiling of cells exposed to particular and intense electromagnetic radiation emitted by the "SG-III" prototype laser facility

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Jiangbin Wei ◽  
Qiwu Shi ◽  
Lidan Xiong ◽  
Guang Xin ◽  
Tao Yi ◽  
...  
Keyword(s):  
Dna Damage ◽  
Pc12 Cells ◽  
Inertial Confinement Fusion ◽  
Biological Effects ◽  
Harmful Effect ◽  
Transcriptome Profiling ◽  
Target Chamber ◽  
Target Range ◽  
Inertial Confinement ◽  
Laser Facility

AbstractThe experiment of inertial confinement fusion by the “ShengGuang (SG)-III” prototype laser facility is a transient and extreme reaction process within several nanoseconds, which could form a very complicated and intense electromagnetic field around the target chamber of the facility and may lead to harmful effect on people around. In particular, the biological effects arising from such specific environment field could hardly be ignored and have never been investigated yet, and thus, we reported on the investigation of the biological effects of radiation on HaCat cells and PC12 cells to preliminarily assess the biological safety of the target range of the "SG-III" prototype laser facility. The viability revealed that the damage of cells was dose-dependent. Then we compared the transcriptomes of exposed and unexposed PC12 cells by RNA-Seq analysis based on Illumina Novaseq 6000 platform and found that most significantly differentially expressed genes with corresponding Gene Ontology terms and pathways were strongly involved in proliferation, transformation, necrosis, inflammation response, apoptosis and DNA damage. Furthermore, we find increase in the levels of several proteins responsible for cell-cycle regulation and tumor suppression, suggesting that pathways or mechanisms regarding DNA damage repair was are quickly activated. It was found that "SG-III" prototype radiation could induce DNA damage and promote apoptotic necrosis.

scholarly journals Target alignment in the Shen-Guang II Upgrade laser facility

2018 ◽  
Vol 6 ◽  
Author(s):  
Lei Ren ◽  
Ping Shao ◽  
Dongfeng Zhao ◽  
Yang Zhou ◽  
Zhijian Cai ◽  
...  
Keyword(s):  
Inertial Confinement Fusion ◽  
Short Pulse ◽  
Three Dimensional ◽  
Nanosecond Laser ◽  
Alignment Error ◽  
Inertial Confinement ◽  
Pulse Beam ◽  
Rotation Sensor ◽  
Confinement Fusion ◽  
Laser Facility

The Shen-Guang II Upgrade (SG-II-U) laser facility consists of eight high-power nanosecond laser beams and one short-pulse picosecond petawatt laser. It is designed for the study of inertial confinement fusion (ICF), especially for conducting fast ignition (FI) research in China and other basic science experiments. To perform FI successfully with hohlraum targets containing a golden cone, the long-pulse beam and cylindrical hohlraum as well as the short-pulse beam and cone target alignment must satisfy tight specifications (30 and $20~\unicode[STIX]{x03BC}\text{m}$ rms for each case). To explore new ICF ignition targets with six laser entrance holes (LEHs), a rotation sensor was adapted to meet the requirements of a three-dimensional target and correct beam alignment. In this paper, the strategy for aligning the nanosecond beam based on target alignment sensor (TAS) is introduced and improved to meet requirements of the picosecond lasers and the new six LEHs hohlraum targets in the SG-II-U facility. The expected performance of the alignment system is presented, and the alignment error is also discussed.

Autonomous pulse shaping method for inertial confinement fusion high power laser facility

2020 ◽  
Vol 161 ◽  
pp. 111983
Author(s):  
Xiaoxia Huang ◽  
Xuewei Deng ◽  
Wei Zhou ◽  
Huaiwen Guo ◽  
Bowang Zhao ◽  
...  
Keyword(s):  
High Power ◽  
Inertial Confinement Fusion ◽  
Pulse Shaping ◽  
Inertial Confinement ◽  
High Power Laser ◽  
Power Laser ◽  
Confinement Fusion ◽  
Laser Facility

scholarly journals Computer modeling of ICF target chamber phenomena

1994 ◽  
Vol 12 (2) ◽  
pp. 125-162 ◽  
Author(s):  
Gregory A. Moses ◽  
Robert R. Peterson
Keyword(s):  
Computer Modeling ◽  
Inertial Confinement Fusion ◽  
High Repetition Rate ◽  
Phase Changes ◽  
Physical Models ◽  
Test Facility ◽  
High Yield ◽  
Target Chamber ◽  
Inertial Confinement ◽  
Design Strategies

The target chamber of an inertial confinement fusion (ICF) power plant or high-yield test facility must be designed to absorb the target produced Xrays and ions and survive the resulting effects. The target chamber conditions must be restored in fractions of a second for high repetition rate power applications. Computer modeling of these phenomena is essential because equivalent conditions cannot be produced in laboratory experiments prior to the first ignition of high-yield ICF targets. Choices of models are dictated by specific reactor design strategies. The two major strategies, gas protection and sacrificial first surfaces, are used as a guide to our discussion. Physical models for ion, electron, and X-ray deposition are discussed, along with physical and numerical modeling of the resulting phase changes intarget chamber structures. The hydrodynamics and radiative transfer in the target chamber vapors and plasmas are central topics.

scholarly journals Surface Contaminant Control Technologies to Improve Laser Damage Resistance of Optics

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Xiaofeng Cheng ◽  
Xinxiang Miao ◽  
Hongbin Wang ◽  
Lang Qin ◽  
Yayun Ye ◽  
...  
Keyword(s):  
High Power ◽  
Inertial Confinement Fusion ◽  
High Energy ◽  
Intense Laser ◽  
Metallic Surface ◽  
Inertial Confinement ◽  
Contamination Control ◽  
Laser Driver ◽  
Laser Facility ◽  
Laser Induced Damage

The large high-power solid lasers, such as the National Ignition Facility (NIF) of America and the Shenguang-III (SG-III) laser facility of China, can output over 2.1 MJ laser pulse for the inertial confinement fusion (ICF) experiments. Because of the enhancement of operating flux and the expansion of laser driver scale, the problem of contamination seriously influences their construction period and operation life. During irradiation by intense laser beams, the contaminants on the metallic surface of beam tubes can be transmitted to the optical surfaces and lead to damage of optical components. For the high-power solid-state laser facilities, contamination control focuses on the slab amplifiers, spatial filters, and final-optical assemblies. In this paper, an effective solution to control contaminations including the whole process of the laser driver is put forward to provide the safe operation of laser facilities, and the detailed technical methods of contamination control such as washing, cleanliness metrology, and cleanliness protecting are also introduced to reduce the probability of laser-induced damage of optics. The experimental results show that the cleanliness level of SG-III laser facility is much better to ensure that the laser facility can safely operate at high energy flux.

General Structure Layout and Design of Target Area of SGIII Facility

2013 ◽  
Vol 765-767 ◽  
pp. 286-290
Author(s):  
Ming Zhi Zhu ◽  
Xiao Juan Chen ◽  
Mei Cong Wang ◽  
Wen Kai Wu ◽  
Gang Chen ◽  
...  
Keyword(s):  
Structural Design ◽  
Inertial Confinement Fusion ◽  
General Structure ◽  
Target Chamber ◽  
Target Area ◽  
Inertial Confinement ◽  
Optical Elements ◽  
Confinement Fusion ◽  
Mechanical Elements ◽  
Structure Layout

ShenGuang III (SGIII) facility will be constructed for research in Inertial Confinement Fusion. In this paper, general structure layout and design of target area of SGIII facility are described. Target area structure support system must provide a stable and precisely platform for optical elements before and during a shot. General structure layout must satisfy the mul-function consideration and logistic priority. The modularity and hardware commonality, cleanliness, and low neutron activation should be considered in the structural design of target area. The general structure layout of target area is rectangle. The target bay and the switchyard have the multi-layered layout to satisfy the demand of transporting beam lasers unidirectionally from south to north and supporting the optics modules and physical diagnostic instruments with different height. The passageways of population & goods flow of target area are designed to include the vertical channels between the different layers and the horizontal channels on the same layer. The opto-mechanical elements (OM) are classified as OM1, OM2, and OM3. The OM1 are the infrastructures. The OM2 include target chamber, the shell of final optics assemblies, the mirror frames, and the beam enclosures. The OM3 is line replaceable units that are attached to the OM2 on kinematic equivalent three-vee mounts.

scholarly journals Laser performance of the SG-III laser facility

2016 ◽  
Vol 4 ◽  
Author(s):  
Wanguo Zheng ◽  
Xiaofeng Wei ◽  
Qihua Zhu ◽  
Feng Jing ◽  
Dongxia Hu ◽  
...  
Keyword(s):  
Inertial Confinement Fusion ◽  
Laser System ◽  
Power Balance ◽  
Inertial Confinement ◽  
Fusion Research ◽  
Laser Performance ◽  
Laser Driver ◽  
Confinement Fusion ◽  
Laser Facility ◽  
Better Than

SG-III laser facility is now the largest laser driver for inertial confinement fusion research in China. The whole laser facility can deliver 180 kJ energy and 60 TW power ultraviolet laser onto target, with power balance better than 10%. We review the laser system and introduce the SG-III laser performance here.

scholarly journals New high-power laser facility PALS—prospects for laser–plasma research

1999 ◽  
Vol 17 (2) ◽  
pp. 179-194 ◽  
Author(s):  
B. RUS ◽  
K. ROHLENA ◽  
J. SKÁLA ◽  
B. KRÁLIKOVÁ ◽  
K. JUNGWIRTH ◽  
...  
Keyword(s):  
High Power ◽  
Inertial Confinement Fusion ◽  
Radiation Transport ◽  
Laser System ◽  
Main Beam ◽  
Inertial Confinement ◽  
X Ray ◽  
Multiple Pulse ◽  
Laser Facility ◽  
Under Construction

In this paper, we report on a new laser facility called PALS (Prague Asterix Laser System), which is currently under construction, and which will house the high-power iodine laser Asterix IV. Upon its completion in late 1999, the PALS facility will be capable of providing single- or multiple-pulse irradiation with a variable pulse duration ranging from 100 to 500 ps. Wavelengths available will be 1.315 μm, 658 nm, and 438 nm. The system will provide one main beam with energy up to 1200 J and two smaller auxiliary beams with a combined energy of up to 100 J. A wide variety of geometries and variable pulse timings is available. We assess PALS' potential for investigating the physics of laser plasmas in inertial confinement fusion, the development and applications of X-ray lasers, X-ray spectroscopy, and radiation transport, using multiple-pulse and extended beam capability.

Decontamination of Phebus Experimental Target Chamber Using Sprayed Foam

2002 ◽  
Author(s):  
B. Fournel ◽  
S. Angot ◽  
P. Joyer
Keyword(s):  
Aluminum Alloy ◽  
Inertial Confinement Fusion ◽  
Target Chamber ◽  
Inertial Confinement ◽  
Confinement Fusion ◽  
Fusion Experiments

Phebus facility was designed in the eighties to lead inertial confinement fusion experiments on deuterium/ tritium targets. It has been decommissioned in 1999. Phebus chamber is an aluminum alloy (5086) sphere of 2,3 m diameter with an inner volume of about 8 m3. The thickness of the chamber is about 12 cm. A large number of openings (around 230) were designed on its surface, for diagnostics implementation during experiments (figure 1).

scholarly journals Demonstration of symcaps to measure implosion symmetry in the foot of the NIF scale 0.7 hohlraums

2009 ◽  
Vol 27 (1) ◽  
pp. 123-127 ◽  
Author(s):  
A. Seifter ◽  
G.A. Kyrala ◽  
S.R. Goldman ◽  
N.M. Hoffman ◽  
J.L. Kline ◽  
...  
Keyword(s):  
Inertial Confinement Fusion ◽  
Inertial Confinement ◽  
X Rays ◽  
X Ray ◽  
Precise Control ◽  
Confinement Fusion ◽  
Laser Facility ◽  
Drive Pulse ◽  
Indirect Drive ◽  
Omega Laser

AbstractImplosions using inertial confinement fusion must be highly symmetric to achieve ignition on the National Ignition Facility. This requires precise control of the drive symmetry from the radiation incident on the ignition capsule. For indirect drive implosions, low mode residual perturbations in the drive are generated by the laser-heated hohlraum geometry. To diagnose the drive symmetry, previous experiments used simulated capsules by which the self-emission X-rays from gas in the center of the capsule during the implosion are used to infer the shape of the drive. However, those experiments used hohlraum radiation temperatures higher than 200 eV (Hauer et al., 1995; Murphy et al., 1998a, 1998b) with small NOVA scale hohlraums under which conditions the symcaps produced large X-ray signals. At the foot of the NIF ignition pulse, where controlling the symmetry has been shown to be crucial for obtaining a symmetric implosion (Clark et al., 2008), the radiation drive is much smaller, reducing the X-ray emission from the imploded capsule. For the first time, the feasibility of using symcaps to diagnose the radiation drive for low radiation temperatures, <120 eV and large 0.7 linear scales NIF Rev3.1 (Haan et al., 2008) vacuum hohlraums is demonstrated. Here we used experiments at the Omega laser facility to demonstrate and develop the symcap technique for tuning the symmetry of the NIF ignition capsule in the foot of the drive pulse.

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