scholarly journals MultiVERSE: a multiplex and multiplex-heterogeneous network embedding approach

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Léo Pio-Lopez ◽  
Alberto Valdeolivas ◽  
Laurent Tichit ◽  
Élisabeth Remy ◽  
Anaïs Baudot

AbstractNetwork embedding approaches are gaining momentum to analyse a large variety of networks. Indeed, these approaches have demonstrated their effectiveness in tasks such as community detection, node classification, and link prediction. However, very few network embedding methods have been specifically designed to handle multiplex networks, i.e. networks composed of different layers sharing the same set of nodes but having different types of edges. Moreover, to our knowledge, existing approaches cannot embed multiple nodes from multiplex-heterogeneous networks, i.e. networks composed of several multiplex networks containing both different types of nodes and edges. In this study, we propose MultiVERSE, an extension of the VERSE framework using Random Walks with Restart on Multiplex (RWR-M) and Multiplex-Heterogeneous (RWR-MH) networks. MultiVERSE is a fast and scalable method to learn node embeddings from multiplex and multiplex-heterogeneous networks. We evaluate MultiVERSE on several biological and social networks and demonstrate its performance. MultiVERSE indeed outperforms most of the other methods in the tasks of link prediction and network reconstruction for multiplex network embedding, and is also efficient in link prediction for multiplex-heterogeneous network embedding. Finally, we apply MultiVERSE to study rare disease-gene associations using link prediction and clustering. MultiVERSE is freely available on github at https://github.com/Lpiol/MultiVERSE.

Author(s):  
Hongming Zhang ◽  
Liwei Qiu ◽  
Lingling Yi ◽  
Yangqiu Song

Network embedding has been proven to be helpful for many real-world problems. In this paper, we present a scalable multiplex network embedding model to represent information of multi-type relations into a unified embedding space. To combine information of different types of relations while maintaining their distinctive properties, for each node, we propose one high-dimensional common embedding and a lower-dimensional additional embedding for each type of relation. Then multiple relations can be learned jointly based on a unified network embedding model. We conduct experiments on two tasks: link prediction and node classification using six different multiplex networks. On both tasks, our model achieved better or comparable performance compared to current state-of-the-art models with less memory use.


2020 ◽  
Vol 34 (04) ◽  
pp. 5371-5378
Author(s):  
Chanyoung Park ◽  
Donghyun Kim ◽  
Jiawei Han ◽  
Hwanjo Yu

Nodes in a multiplex network are connected by multiple types of relations. However, most existing network embedding methods assume that only a single type of relation exists between nodes. Even for those that consider the multiplexity of a network, they overlook node attributes, resort to node labels for training, and fail to model the global properties of a graph. We present a simple yet effective unsupervised network embedding method for attributed multiplex network called DMGI, inspired by Deep Graph Infomax (DGI) that maximizes the mutual information between local patches of a graph, and the global representation of the entire graph. We devise a systematic way to jointly integrate the node embeddings from multiple graphs by introducing 1) the consensus regularization framework that minimizes the disagreements among the relation-type specific node embeddings, and 2) the universal discriminator that discriminates true samples regardless of the relation types. We also show that the attention mechanism infers the importance of each relation type, and thus can be useful for filtering unnecessary relation types as a preprocessing step. Extensive experiments on various downstream tasks demonstrate that DMGI outperforms the state-of-the-art methods, even though DMGI is fully unsupervised.


Author(s):  
Léo Pio-Lopez

Drug repositioning (also called drug repurposing) is a strategy for identifying new therapeutic targets for existing drugs. This approach is of great importance in pharmacology as it is a faster and cheaper way to develop new medical treatments. In this paper, we present, to our knowledge, the first application of multiplex-heterogeneous network embedding to drug repositioning. Network embedding learns the vector representations of nodes, opening the whole machine learning toolbox for a wide variety of applications including link prediction, node labelling or clustering. So far, the application of network embedding for drug repositioning focused on heterogeneous networks. Our approach for drug repositioning is based on multiplex-heterogeneous network embedding. Such method allows the richness and complexity of multiplex and heterogeneous networks to be projected in the same vector space. In other words, multiplex-heterogeneous networks aggregate different multi-omics data in the same network representation. We validate the approach on a task of link prediction and on a case study for SARS-CoV2 drug repositioning. Experimental results show that our approach is highly robust and effective for finding new drug-target associations.


Author(s):  
Liang Yang ◽  
Yuexue Wang ◽  
Junhua Gu ◽  
Chuan Wang ◽  
Xiaochun Cao ◽  
...  

Motivated by the capability of Generative Adversarial Network on exploring the latent semantic space and capturing semantic variations in the data distribution, adversarial learning has been adopted in network embedding to improve the robustness. However, this important ability is lost in existing adversarially regularized network embedding methods, because their embedding results are directly compared to the samples drawn from perturbation (Gaussian) distribution without any rectification from real data. To overcome this vital issue, a novel Joint Adversarial Network Embedding (JANE) framework is proposed to jointly distinguish the real and fake combinations of the embeddings, topology information and node features. JANE contains three pluggable components, Embedding module, Generator module and Discriminator module. The overall objective function of JANE is defined in a min-max form, which can be optimized via alternating stochastic gradient. Extensive experiments demonstrate the remarkable superiority of the proposed JANE on link prediction (3% gains in both AUC and AP) and node clustering (5% gain in F1 score).


2017 ◽  
Vol 28 (08) ◽  
pp. 1750101 ◽  
Author(s):  
Yabing Yao ◽  
Ruisheng Zhang ◽  
Fan Yang ◽  
Yongna Yuan ◽  
Qingshuang Sun ◽  
...  

In complex networks, the existing link prediction methods primarily focus on the internal structural information derived from single-layer networks. However, the role of interlayer information is hardly recognized in multiplex networks, which provide more diverse structural features than single-layer networks. Actually, the structural properties and functions of one layer can affect that of other layers in multiplex networks. In this paper, the effect of interlayer structural properties on the link prediction performance is investigated in multiplex networks. By utilizing the intralayer and interlayer information, we propose a novel “Node Similarity Index” based on “Layer Relevance” (NSILR) of multiplex network for link prediction. The performance of NSILR index is validated on each layer of seven multiplex networks in real-world systems. Experimental results show that the NSILR index can significantly improve the prediction performance compared with the traditional methods, which only consider the intralayer information. Furthermore, the more relevant the layers are, the higher the performance is enhanced.


Author(s):  
Sarbendu Rakshit ◽  
Bidesh K. Bera ◽  
Jürgen Kurths ◽  
Dibakar Ghosh

Most of the previous studies on synchrony in multiplex networks have been investigated using different types of intralayer network architectures which are either static or temporal. Effect of a temporal layer on intralayer synchrony in a multilayered network still remains elusive. In this paper, we discuss intralayer synchrony in a multiplex network consisting of static and temporal layers and how a temporal layer influences other static layers to enhance synchrony simultaneously. We analytically derive local stability conditions for intralayer synchrony based on the master stability function approach. The analytically derived results are illustrated by numerical simulations on up to five-layers multiplex networks with the paradigmatic Lorenz system as the node dynamics in each individual layer.


Complexity ◽  
2017 ◽  
Vol 2017 ◽  
pp. 1-13 ◽  
Author(s):  
Nicolò Musmeci ◽  
Vincenzo Nicosia ◽  
Tomaso Aste ◽  
Tiziana Di Matteo ◽  
Vito Latora

We propose here a multiplex network approach to investigate simultaneously different types of dependency in complex datasets. In particular, we consider multiplex networks made of four layers corresponding, respectively, to linear, nonlinear, tail, and partial correlations among a set of financial time series. We construct the sparse graph on each layer using a standard network filtering procedure, and we then analyse the structural properties of the obtained multiplex networks. The study of the time evolution of the multiplex constructed from financial data uncovers important changes in intrinsically multiplex properties of the network, and such changes are associated with periods of financial stress. We observe that some features are unique to the multiplex structure and would not be visible otherwise by the separate analysis of the single-layer networks corresponding to each dependency measure.


Complexity ◽  
2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
Ruili Lu ◽  
Pengfei Jiao ◽  
Yinghui Wang ◽  
Huaming Wu ◽  
Xue Chen

Great achievements have been made in network embedding based on single-layer networks. However, there are a variety of scenarios and systems that can be presented as multiplex networks, which can reveal more interesting patterns hidden in the data compared to single-layer networks. In the field of network embedding, in order to project the multiplex network into the latent space, it is necessary to consider richer structural information among network layers. However, current methods for multiplex network embedding mostly focus on the similarity of nodes in each layer of the network, while ignoring the similarity between different layers. In this paper, for multiplex network embedding, we propose a Layer Information Similarity Concerned Network Embedding (LISCNE) model considering the similarities between layers. Firstly, we introduce the common vector for each node shared by all layers and layer vectors for each layer where common vectors obtain the overall structure of the multiplex network and layer vectors learn semantics for each layer. We get the node embeddings in each layer by concatenating the common vectors and layer vectors with the consideration that the node embedding is related not only to the surrounding neighbors but also to the overall semantics. Furthermore, we define an index to formalize the similarity between different layers and the cross-network association. Constrained by layer similarity, the layer vectors with greater similarity are closer to each other and the aligned node embedding in these layers is also closer. To evaluate our proposed model, we conduct node classification and link prediction tasks to verify the effectiveness of our model, and the results show that LISCNE can achieve better or comparable performance compared to existing baseline methods.


Author(s):  
Xiaofang Zhao ◽  
Yuhong Liu ◽  
Zhigang Jin

AbstractAs one of the hot research directions in natural language processing, sentiment analysis has received continuous and extensive attention. Different from explicit sentiment words indicating sentiment polarity, implicit sentiment analysis is a more challenging problem due to the lack of sentiment words, which makes it inadequate to use traditional sentiment analysis method to judge the polarity of implicit sentiment. This paper takes sentiment analysis as a special sign link prediction problem, which is different from traditional text-based method. In particular, by performing the word graph-based text level information embedding and heterogeneous social network information embedding (i.e. user social relationship network embedding, and user-entity sentiment network embedding), the proposed scheme learns the highly nonlinear representations of network nodes, explores early fusion method to combine the strength of these two types of embedding modeling, optimizes all parameters simultaneously and creates enhanced context representations, leading to better capture of implicit sentiment polarity. The proposed method has been examined on real-world dataset, for implicit sentiment link prediction task. The experimental results demonstrate that the proposed method outperforms state-of-the-art schemes, including LINE, node2vec, and SDNE, by 20.2%, 19.8%, and 14.0%, respectively, on accuracy, and achieves at least 14% gains on AUROC. For sentiment analysis accuracy, the proposed method achieves AUROC of 80.6% and accuracy of 78.3%, which is at least 31% better than other models. This work can provide useful guidance on the implicit sentiment analysis.


2020 ◽  
Vol 7 (7) ◽  
pp. 191928
Author(s):  
Amir Mahdi Abdolhosseini-Qomi ◽  
Seyed Hossein Jafari ◽  
Amirheckmat Taghizadeh ◽  
Naser Yazdani ◽  
Masoud Asadpour ◽  
...  

Networks are invaluable tools to study real biological, social and technological complex systems in which connected elements form a purposeful phenomenon. A higher resolution image of these systems shows that the connection types do not confine to one but to a variety of types. Multiplex networks encode this complexity with a set of nodes which are connected in different layers via different types of links. A large body of research on link prediction problem is devoted to finding missing links in single-layer (simplex) networks. In recent years, the problem of link prediction in multiplex networks has gained the attention of researchers from different scientific communities. Although most of these studies suggest that prediction performance can be enhanced by using the information contained in different layers of the network, the exact source of this enhancement remains obscure. Here, it is shown that similarity w.r.t. structural features (eigenvectors) is a major source of enhancements for link prediction task in multiplex networks using the proposed layer reconstruction method and experiments on real-world multiplex networks from different disciplines. Moreover, we characterize how low values of similarity w.r.t. structural features result in cases where improving prediction performance is substantially hard.


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