scholarly journals High neutrophil to lymphocytes ratio is associated with nutritional risk in hospitalised, unselected cancer patients: a cross-sectional study

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Jéssika M Siqueira ◽  
Jéssika D P Soares ◽  
Thaís C Borges ◽  
Tatyanne L N Gomes ◽  
Gustavo D Pimentel
Keyword(s):  
Logistic Regression ◽  
Cancer Patients ◽  
Systemic Inflammation ◽  
Roc Curve ◽  
Cross Sectional Study ◽  
Nutritional Risk ◽  
Sectional Study ◽  
Cross Sectional ◽  
Cut Point ◽  
Nrs 2002

AbstractCancer patients possess metabolic and pathophysiological changes and an inflammatory environment that leads to malnutrition. This study aimed to (i) determine whether there is an association between neutrophil-to-lymphocyte ratio (NLR) and nutritional risk, and (ii) identify the cut-off value of NLR that best predicts malnutrition by screening for nutritional risk (NRS 2002). This cross-sectional study included 119 patients with unselected cancer undergoing chemotherapy and/or surgery. The NRS 2002 was applied within 24 h of hospitalisation to determine the nutritional risk. Systemic inflammation was assessed by blood collection, and data on C-reactive protein (CRP), neutrophils, and lymphocytes were collected for later calculation of NLR. A receiver operating characteristic (ROC) curve was used to identify the best cut-point for NLR value that predicted nutritional risk. Differences between the groups were tested using the Student’s t-, Mann–Whitney U and Chi-Square tests. Logistic regression analyses were performed to assess the association between NLR and nutritional risk. The ROC curve showed the best cut-point for predicting nutritional risk was NLR > 5.0 (sensitivity, 60.9%; specificity, 76.4%). The NLR ≥ 5.0 group had a higher prevalence of nutritional risk than the NLR < 5.0 group (NLR ≥ 5.0: 73.6% vs. NLR < 5.0: 37.9%, p = 0.001). The NLR group ≥ 5.0 showed higher values of CRP and NLR than the NLR < 5.0 group. In addition, patients with NLR ≥ 5.0 also had higher NRS 2002 values when compared to the NLR < 5.0 group (NLR ≥ 5.0: 3.0 ± 1.1 vs. NLR < 5.0: 2.3 ± 1.2, p = 0.0004). Logistic regression revealed an association between NRS and NLR values. In hospitalised unselected cancer patients, systemic inflammation measured by NLR was associated with nutritional risk. Therefore, we highlight the importance of measuring the NLR in clinical practice, with the aim to detect nutritional risk.

scholarly journals Standardized Phase Angle as a Prognostic and Nutritional Status Tool for Pancreatic Cancer Patients Undergoing Pancreaticoduodenectomy: A Cross-sectional Study (P12-025-19)

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Wei Chen ◽  
Shengnan Zhou
Keyword(s):  
Pancreatic Cancer ◽  
Postoperative Complications ◽  
Nutritional Status ◽  
Cancer Patients ◽  
Phase Angle ◽  
Cross Sectional Study ◽  
Nutritional Risk ◽  
Sectional Study ◽  
Cross Sectional ◽  
Nrs 2002

Abstract Objectives This study investigated the use of standardized phase angle (SPA), determined by bioelectrical impedance analysis (BIA), as a nutrition status tool and prognostic factor for complications associated with pancreaticoduodenectomy (PD) in pancreatic cancer patients. Methods A cross-sectional study was conducted with 49 participants. All participants were assessed for nutritional risk and nutritional status using Nutritional Risk Screening 2002 (NRS-2002), Subjective Global Assessment (SGA) tools, Global Leadership Initiative on Malnutrition (GLIM) tool and BIA. The Clavien-Dindo classification method for surgical complications was used to identify and classify postoperative complications. Independent-samples T-tests, chi-square tests and Spearman correlation analyses were used to evaluate the association between SPA, nutrition and postoperative complications. Results A total of 49 patients were enrolled, and 20 patients (40%) had postoperative complications. The SPA value for the nourished group was significantly higher than the SPA value for the malnourished group (P = 0.021, 0.019, 0.023). Patients who were below the SPA cut-off values (−1.015, −1.065, and −0.69) were more likely to have postoperative complications (P = 0.009), whereas NRS-2002, SGA, and GLIM scores were not associated with postoperative complications. The SPA value of the group with complications was significantly lower than that of the group without complications (P = 0.004). The SPA threshold value for predicting postoperative complications in pancreatic cancer was −1.095 (AUC 0.737; 95% CI, 0.59, 0.88; P = 0.005). Conclusions The SPA is a prognostic indicator of postoperative complications in pancreatic cancer patients undergoing PD and is an effective tool for assessing nutritional status in pancreatic cancer patients. Funding Sources none. Supporting Tables, Images and/or Graphs

scholarly journals Evaluation of Nutritional Risk and Prevalence of Obesity in Patients with Covid-19 in A Reference Hospital in Salvador, Bahia, Brazil: A Cross-Sectional Study

2021 ◽  
Vol 14 (01) ◽  
pp. 011-015
Author(s):  
Rodrigo Fernandes Weyll Pimentel ◽  
Gilson Cruz de Moraes ◽  
Shalla Gomes Cavalcanti Barcelos ◽  
Pedro Carlos Muniz de Figueiredo ◽  
Magno Conceição Das Merces
Keyword(s):  
Cross Sectional Study ◽  
Nutritional Risk ◽  
Sectional Study ◽  
Cross Sectional ◽  
High Prevalence ◽  
Reference Hospital ◽  
Prevalence Of Obesity ◽  
Nrs 2002 ◽  
Study Type ◽  
Nutritional Risk Screening

Abstract Introduction The Coronavirus has spread to almost every country in the world, causing the coronavirus disease (COVID-19). The coronavirus stands out among the other infections especially by it's high contagious power and important effects on the respiratory system. The COVID-19 has differents ways of presentation and these are influenced by the patient's previous nutricional status, correlated with the patient's lifestyle and comorbities. Objective this survey seeks to analyze the nutritional status and the prevalence of obesity in patients hospitalized with SARS-CoV-2. Methods: this is a descriptive, prospective and cross-sectional study type, which 41 patients affected by COVID-19 were interviewed. Patient's weight and height were used to assess the BMI, and nutritional risk assessment was performed using the Nutritional Risk Screening tool (NRS 2002). For the analysis, Absolute (AF) and Relative Frequency (RF), the mean and the standard deviation were calculated. Results It was observerd that 78% of the participants had a high nutritional risk, while only 22% had a low nutritional risk. Besides that, 34% showed overweight and 41.4% showed obesity. Conclusion the existence of a high prevalence of increased nutritional risk was evidenced, in addition to the high frequency of overweight in patients affected by SARS-CoV-2.

scholarly journals A cross-sectional study on associations of physical symptoms, health self-efficacy and suicidal ideation among Chinese hospitalized cancer patients following diagnosis.

2020 ◽  
Author(s):  
Qingyi Xu ◽  
Shuhua Jia ◽  
Maiko Fukasawa ◽  
Lin Lin ◽  
Jun Na ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Suicidal Ideation ◽  
Cancer Patients ◽  
Self Efficacy ◽  
Epidemiological Studies ◽  
Cross Sectional Study ◽  
Physical Symptoms ◽  
Sectional Study ◽  
Cross Sectional ◽  
The Impact

Abstract Background: Epidemiological studies have shown elevated suicide risk in cancer patients compare with the general population. This study was performed to examine the association between physical symptoms and suicidal ideation among Chinese hospitalized cancer patients and test the modifying effect of health self-efficacy on this association. Methods: A cross-sectional study was conducted among 544 cancer patients from oncology settings in two general hospitals in northeast China via face-to-face interviews. Suicidal ideation was measured by using four items from the Yale Evaluation of Suicidality scale, dichotomized into a positive and negative score. Multivariable logistic regression was applied to examine the impact of physical symptoms, health self-efficacy and their interactions on suicidal ideation.Results: We found a suicidal ideation rate of 26.3% in patients following cancer diagnosis. Logistic regression showed that insomnia (aOR=1.84, 95% CI 1.13 to 3.00, p =0.015), lack of appetite (aOR=2.14, 95% CI 1.26 to 3.64, p =0.005) were positively associated with suicidal ideation, low health self-efficacy showed a marginally significant exaggerating effect on the association between pain and suicidal ideation (aOR = 2.77, 95% CI 0.99 to 7.74, p =0.053), even after controlling for significant socio-demographic, clinical characteristics and depression. Conclusions: These findings demonstrate the associations between insomnia、lack of appetite and suicidal ideation and highlight the potential moderating role of health self-efficacy in the identification and prevention of suicide among cancer patients.

scholarly journals A cross-sectional study on associations of physical symptoms, health self-efficacy, and suicidal ideation among Chinese hospitalized cancer patients

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Qingyi Xu ◽  
Shuhua Jia ◽  
Maiko Fukasawa ◽  
Lin Lin ◽  
Jun Na ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Suicidal Ideation ◽  
Cancer Patients ◽  
Self Efficacy ◽  
Epidemiological Studies ◽  
Cross Sectional Study ◽  
Physical Symptoms ◽  
Sectional Study ◽  
Cross Sectional ◽  
Increased Risk

Abstract Background Epidemiological studies have shown increased risk of suicide in cancer patients compared with the general population. The present study aimed to examine the association between physical symptoms and suicidal ideation in Chinese hospitalized cancer patients and test the modifying effect of health self-efficacy on the association. Methods A cross-sectional study was conducted with 544 hospitalized cancer patients in two general hospitals in northeast China via face-to-face interviews. Suicidal ideation was measured by using the first four items on the Yale Evaluation of Suicidality scale and then dichotomized into a positive and negative score. Multivariate logistic regression analyses were conducted to examine the impacts of physical symptoms, health self-efficacy, and their interactions on suicidal ideation. Results The suicidal ideation rate was 26.3% in the enrolled cancer patients. Logistic regression showed that insomnia (aOR = 1.84, 95% CI 1.13 to 3.00, p = 0.015) and lack of appetite (aOR = 2.14, 95% CI 1.26 to 3.64, p = 0.005) were significantly associated with suicidal ideation. Low health self-efficacy had a marginally significant exaggerating effect on the association between pain and suicidal ideation (aOR = 2.77, 95% CI 0.99 to 7.74, p = 0.053), after adjusting for significant socio-demographics, clinical characteristics, and depression. Conclusions These findings demonstrate significant associations between physical symptoms (insomnia and/or lack of appetite) and suicidal ideation and highlight the potential modifying role of health self-efficacy in the identification and prevention of suicide among cancer patients.

scholarly journals A cross-sectional study on associations of physical symptoms, health self-efficacy, and suicidal ideation among Chinese hospitalized cancer patients

2020 ◽  
Author(s):  
Qingyi Xu ◽  
Shuhua Jia ◽  
Maiko Fukasawa ◽  
Lin Lin ◽  
Jun Na ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Suicidal Ideation ◽  
Cancer Patients ◽  
Self Efficacy ◽  
Epidemiological Studies ◽  
Cross Sectional Study ◽  
Physical Symptoms ◽  
Sectional Study ◽  
Cross Sectional ◽  
Increased Risk

Abstract Background: Epidemiological studies have shown increased risk of suicide in cancer patients compared with the general population. The present study aimed to examine the association between physical symptoms and suicidal ideation in Chinese hospitalized cancer patients and test the modifying effect of health self-efficacy on the association. Methods: A cross-sectional study was conducted with 544 hospitalized cancer patients in two general hospitals in northeast China via face-to-face interviews. Suicidal ideation was measured by using the first four items on the Yale Evaluation of Suicidality scale and then dichotomized into a positive and negative score. Multivariate logistic regression analyses were conducted to examine the impacts of physical symptoms, health self-efficacy, and their interactions on suicidal ideation.Results: The suicidal ideation rate was 26.3% in the enrolled cancer patients. Logistic regression showed that insomnia (aOR=1.84, 95% CI 1.13 to 3.00, p =0.015) and lack of appetite (aOR=2.14, 95% CI 1.26 to 3.64, p =0.005) were significantly associated with suicidal ideation. Low health self-efficacy had a marginally significant exaggerating effect on the association between pain and suicidal ideation (aOR = 2.77, 95% CI 0.99 to 7.74, p =0.053), after adjusting for significant socio-demographics, clinical characteristics, and depression. Conclusions: These findings demonstrate significant associations between physical symptoms (insomnia and/or lack of appetite) and suicidal ideation and highlight the potential modifying role of health self-efficacy in the identification and prevention of suicide among cancer patients.

scholarly journals ANALISIS TERJADINYA KARIES GIGI BERDASARKAN PEMERIKSAAN KADAR MUC7 DAN ENZIM GLUKOSILTRANSFERASE (GTF) SALIVA PADA ANAK-ANAKKARYAWAN PTPN VIII YANG BERUMUR 12-13 TAHUN - Dental Caries Analysis Based On Salivary Examination Of Muc7 Levels and Enzyme Glucosyltransferase (gtf) In 12-13 Years Old Children PTPN VIII Employees

2015 ◽  
Vol 5 (1) ◽  
Author(s):  
Sjazili S. Muhibat
Keyword(s):  
At Risk ◽  
Logistic Regression ◽  
Dental Caries ◽  
Roc Curve ◽  
Soft Tissues ◽  
Bacterial Pathogen ◽  
Cross Sectional Study ◽  
Rank Test ◽  
Sectional Study ◽  
Cross Sectional

AbstrakKaries gigi merupakan penyakit infeksi multifaktorial, faktor etiologi tersebut saling berkaitan satu sama lainnya dan digambarkan sebagai empat lingkaran yang saling berimpitan satu sama lainnya. Protein saliva MUC7 yang terdapat dalam saliva berperan penting dalam melindungi jaringan lunak dan keras rongga mulut dari infeksi bakteri patogen. Tujuan penelitian ini untuk mengetahui kaitan antara MUC7 dan glukosiltransferase dengan karies gigi, yang dapat menimbulkan dugaan bahwa MUC7 dan glukosiltransferase berperan penting terjadi karies gigi. Motode penelitian ini bersifat cross sectional study di lapangan dan laboratorium. Sampel penelitian ini adalah 138 orang anak karyawan PTPN VIII Pengalengan usia 12-13 tahun. Pada penelitian ini digunakan analisis chi kuadrat, korelasi rank Spearman, analisis regresi logistik ganda dan kurva ROC.  Hasil penelitian terdapat korelasi yang signifikan antara MUC7 dengan karies gigi, nilai koeffisien korelasi 0,209* dengan p 0,014, dan tidak terdapat korelasi yang signifikan antara glukosiltransferase dengan karies gigi. Hasil perhitungan dengan regresi logistic ganda diperoleh hubungan yang signifikan antara MUC7, glukosiltransferase (GTF) dengan karies gigi. Hasil kurva ROC diperoleh bahwa kadar MUC7  ≤604,02 ng/ml akan berrisiko terjadinya karies gigi 2,085 kali bila dibandingkan dengan kadar MUC7 >604,02.ng/ml. Sedangkan kadar Gtf ≤5,247 ng/ml juga berrisiko terjadi karies gigi sebesar 2,273 kali dibandingkan dengan kadar Gtf >5,247 ng/ml. Simpulan penelitian ini adanya korelasi yang signifikan antara MUC7, GTF dengan karies gigi. Menunjukkan pula bahwa rendahnya kadar MUC7 dan glukosiltrans ferase (GTF) lebih berrisiko terhadap terjadinya karies gigi. Kata kunci; MUC7, glukosiltransferase (GTF), karies gigiAbstractDental caries is a multifactorial infectious disease, which the etiologic factors are related each other and are shown as four interlocking circles coincide with each other. MUC7 salivary proteins plays an important role in protecting the hard and soft tissues of the oral cavity from bacterial pathogen infection. The aim of this research was to each other between MUC7 and glucosyltransferase to dental caries, which can give rise to allegations that the MUC7 and glucosyltransferase plays an important role occur of dental caries. Method of this study is a cross sectional in the field and laboratory. The samples were 138 the children of employees of PTPN VIII Pengalengan 12-13 years old. Analyses of this study are χ2, Spearman's rank test, multiple regression, logistic regression, and ROC curve. The results there was a significant correlation between MUC7 with dental caries, the value of the correlation coefficient 0.209* and p= 0.014, and there was no significant correlation between the glucosyltransferase to dental caries. Calculation of logistic regression obtained significant relationship between MUC7, glucosyltransferase (GTF) with dental caries. The result of ROC curve was obtained that MUC7 levels ≤ 604.02 ng/ml will be at risk 2,085 times dental caries levels when compared with MUC7> 604.02 ng/ml. While the GTF levels ≤ 5,247 ng/ml are also at risk of dental caries occurs 2,273 times compared to the GTF levels> 5,247 ng / ml. The conclusions of this study are significant correlation between MUC7, GTF to dental caries. Also showed that low level of MUC7 and glucosyltransferase (GTF) is more at risk for dental caries.Key word: MUC7, glucosyltransferase, dental caries.

scholarly journals Omitting the First Step of GLIM Framework Yielded Better Accordance With PG-SGA in Chinese Ambulatory Cancer Patients: a Prospective Cross-sectional Study

2021 ◽  
Author(s):  
Yanfei Wang ◽  
Ziqi Liu ◽  
yunyi Wang ◽  
Xiaoyan Chen ◽  
Zhongfen Liu ◽  
...  
Keyword(s):  
Cancer Patients ◽  
Screening Tool ◽  
Cross Sectional Study ◽  
Screening Tools ◽  
Nutritional Risk ◽  
Severe Malnutrition ◽  
Sectional Study ◽  
Cross Sectional ◽  
Nutrition Screening ◽  
Predictive Values

Abstract Background and Aims: The Global Leadership Initiative on Malnutrition (GLIM) criteria is a new framework for diagnosing malnutrition in combination of phenotypic and etiologic criteria after nutrition screening using validated screening tools. The aim of this study was to evaluate the efficacy of malnutrition screening tool (MST), malnutrition universal screening tool (MUST) and nutritional risk screening 2002 (NRS2002) as the first step of GLIM framework in comparison to Patients-Generated Subjective Global Assessment (PG-SGA) in Chinese ambulatory cancer patients.Methods: A single-center prospective cross-sectional study was conducted. Nutritional screening and assessment were performed within 4h after admission to the hospital using a structured questionnaire including MST, MUST, NRS2002, PG-SGA and GLIM, with supplement information of calf circumference (CC) measurement and body composition measurement using bioelectrical impedance analysis (BIA). Malnutrition diagnosis made by GLIM framework using MST, MUST or NRS2002 as the first step or without screening step were compared to PG-SGA separately. Sensitivity, specificity, positive (PPV) and negative (NPV) predictive values and κ values were used to evaluate performance of the screening tools.Results: Of the 562 included patients, Of the participants 62.8% (355/562) were male and 37.2% (210/562) were female, with a male to female radio of 1.69:1. The median age of the patients was 59.0 years (range, 21-82y; interquels range 52.0-65.0y). From the 562 patients included in the study, 41.8% of patients were evaluated as malnutrition (PG-SGA≥4) and 11.9% were diagnosed as severe malnutrition (PG-SGA D). For GLIM criteria, omitting the screening step yielded fair accordance with PG-SGA in diagnosing malnutrition (κ=0.623) and severe malnutrition (κ=0.515). Using MUST as the first step of GLIM framework has better performance (κ=0.614; κ=0.515) than using MST (κ=0.504, κ=0.496) or NRS2002 (κ=0.363, κ=0.503) as the screening tool regardless of severity gradings.Conclusions: Using PG-SGA as the standard, GLIM framework omitting first step has better performance compared with using MST, MUST or NRS2002 as the screening tool. Among the screening tools validated to be used in the first step of GLIM framework, MUST may be the better choice for ambulatory cancer patients.

scholarly journals A cross-sectional study on associations of physical symptoms, health self-efficacy and suicidal ideation among Chinese hospitalized cancer patients following diagnosis.

2020 ◽  
Author(s):  
Qingyi Xu ◽  
Shuhua Jia ◽  
Maiko Fukasawa ◽  
Lin Lin ◽  
Jun Na ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Suicidal Ideation ◽  
Cancer Patients ◽  
Self Efficacy ◽  
Cross Sectional Study ◽  
Physical Symptoms ◽  
Life Questionnaire ◽  
Sectional Study ◽  
Cross Sectional ◽  
The Impact

Abstract Background: To examine the association between physical symptoms and suicidal ideation among Chinese hospitalized cancer patients post-diagnosis, and test the modifying effect of health self-efficacy on this association. Methods: A cross-sectional study was conducted among 544 cancer patients from oncology setting in two general hospitals in northeastern China. Suicidal ideation data was collected by face-to-face interview using the Yale Evaluation of Suicidality scale (YES). Patients also rated on the McGill Quality of Life Questionnaire (MQOL), the Hamilton Depression Rating scale (HAMD-17) and the Strategies Used by People to Promote Health scale (SUPPH). Multivariable logistic regression was applied to examine the impact of physical symptoms, health self-efficacy and their interactions on suicidal ideation. Results: We found a suicidal ideation rate of 26.3% in patients following cancer diagnosis. Logistic regression showed that insomnia (aOR=1.84, 95% CI 1.13 to 3.00, p =0.015), lack of appetite (aOR=2.14, 95% CI 1.26 to 3.64, p =0.005) were significantly associated with suicidal ideation, low health self-efficacy showed a marginally significant exaggerating effect on the association between pain and suicidal ideation (aOR = 2.77, 95% CI 0.99 to 7.74, p =0.053), even after controlling socio-demographic, clinical characteristics and depression. Conclusions: Insomnia, loss of appetite, even after adjusting depression, are associated with suicidal ideation, health self-efficacy play a moderating role on pain and suicidal ideation among Chinese cancer patients. Paying attention to these physical symptoms and promoting the sense of health self-efficacy could be useful for suicide intervention.

scholarly journals A cross-sectional study on associations of physical symptoms, health self-efficacy, and suicidal ideation among Chinese hospitalized cancer patients.

2020 ◽  
Author(s):  
Qingyi Xu ◽  
Shuhua Jia ◽  
Maiko Fukasawa ◽  
Lin Lin ◽  
Jun Na ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Suicidal Ideation ◽  
Cancer Patients ◽  
Self Efficacy ◽  
Epidemiological Studies ◽  
Cross Sectional Study ◽  
Physical Symptoms ◽  
Sectional Study ◽  
Cross Sectional ◽  
Increased Risk

Abstract Background: Epidemiological studies have shown increased risk of suicide in cancer patients compared with the general population. The present study aimed to examine the association between physical symptoms and suicidal ideation in Chinese hospitalized cancer patients and test the modifying effect of health self-efficacy on the association. Methods: A cross-sectional study was conducted with 544 hospitalized cancer patients in two general hospitals in northeast China via face-to-face interviews. Suicidal ideation was measured by using the first four items on the Yale Evaluation of Suicidality scale and then dichotomized into a positive and negative score. Multivariate logistic regression analyses were conducted to examine the impacts of physical symptoms, health self-efficacy, and their interactions on suicidal ideation. Results: The suicidal ideation rate was 26.3% in the enrolled cancer patients. Logistic regression showed that insomnia (aOR=1.84, 95% CI 1.13 to 3.00, p =0.015) and lack of appetite (aOR=2.14, 95% CI 1.26 to 3.64, p =0.005) were significantly associated with suicidal ideation. Low health self-efficacy had a marginally significant exaggerating effect on the association between pain and suicidal ideation (aOR = 2.77, 95% CI 0.99 to 7.74, p =0.053), after adjusting for significant socio-demographics, clinical characteristics, and depression. Conclusions: These findings demonstrate significant associations between physical symptoms (insomnia and/or lack of appetite) and suicidal ideation and highlight the potential modifying role of health self-efficacy in the identification and prevention of suicide among cancer patients.

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