scholarly journals A convolutional neural-network framework for modelling auditory sensory cells and synapses

2021 ◽  
Vol 4 (1) ◽  
Author(s):  
Fotios Drakopoulos ◽  
Deepak Baby ◽  
Sarah Verhulst

AbstractIn classical computational neuroscience, analytical model descriptions are derived from neuronal recordings to mimic the underlying biological system. These neuronal models are typically slow to compute and cannot be integrated within large-scale neuronal simulation frameworks. We present a hybrid, machine-learning and computational-neuroscience approach that transforms analytical models of sensory neurons and synapses into deep-neural-network (DNN) neuronal units with the same biophysical properties. Our DNN-model architecture comprises parallel and differentiable equations that can be used for backpropagation in neuro-engineering applications, and offers a simulation run-time improvement factor of 70 and 280 on CPU or GPU systems respectively. We focussed our development on auditory neurons and synapses, and show that our DNN-model architecture can be extended to a variety of existing analytical models. We describe how our approach for auditory models can be applied to other neuron and synapse types to help accelerate the development of large-scale brain networks and DNN-based treatments of the pathological system.

2020 ◽  
Author(s):  
Fotios Drakopoulos ◽  
Deepak Baby ◽  
Sarah Verhulst

AbstractIn classical computational neuroscience, transfer functions are derived from neuronal recordings to derive analytical model descriptions of neuronal processes. This approach has resulted in a variety of Hodgkin-Huxley-type neuronal models, or multi-compartment synapse models, that accurately mimic neuronal recordings and have transformed the neuroscience field. However, these analytical models are typically slow to compute due to their inclusion of dynamic and nonlinear properties of the underlying biological system. This drawback limits the extent to which these models can be integrated within large-scale neuronal simulation frameworks and hinders an uptake by the neuro-engineering field which requires fast and efficient model descriptions. To bridge this translational gap, we present a hybrid, machine-learning and computational-neuroscience approach that transforms analytical sensory neuron and synapse models into artificial-neural-network (ANN) neuronal units with the same biophysical properties. Our ANN-model architecture comprises parallel and differentiable equations that can be used for backpropagation in neuro-engineering applications, and offers a simulation run-time improvement factor of 70 and 280 on CPU or GPU systems respectively. We focussed our development on auditory sensory neurons and synapses, and show that our ANN-model architecture generalizes well to a variety of existing analytical models of different complexity. The model training and development approach we present can easily be modified for other neuron and synapse types to accelerate the development of large-scale brain networks and to open up avenues for ANN-based treatments of the pathological system.


2020 ◽  
Vol 39 (6) ◽  
pp. 8823-8830
Author(s):  
Jiafeng Li ◽  
Hui Hu ◽  
Xiang Li ◽  
Qian Jin ◽  
Tianhao Huang

Under the influence of COVID-19, the economic benefits of shale gas development are greatly affected. With the large-scale development and utilization of shale gas in China, it is increasingly important to assess the economic impact of shale gas development. Therefore, this paper proposes a method for predicting the production of shale gas reservoirs, and uses back propagation (BP) neural network to nonlinearly fit reservoir reconstruction data to obtain shale gas well production forecasting models. Experiments show that compared with the traditional BP neural network, the proposed method can effectively improve the accuracy and stability of the prediction. There is a nonlinear correlation between reservoir reconstruction data and gas well production, which does not apply to traditional linear prediction methods


2020 ◽  
Vol 2020 (10) ◽  
pp. 181-1-181-7
Author(s):  
Takahiro Kudo ◽  
Takanori Fujisawa ◽  
Takuro Yamaguchi ◽  
Masaaki Ikehara

Image deconvolution has been an important issue recently. It has two kinds of approaches: non-blind and blind. Non-blind deconvolution is a classic problem of image deblurring, which assumes that the PSF is known and does not change universally in space. Recently, Convolutional Neural Network (CNN) has been used for non-blind deconvolution. Though CNNs can deal with complex changes for unknown images, some CNN-based conventional methods can only handle small PSFs and does not consider the use of large PSFs in the real world. In this paper we propose a non-blind deconvolution framework based on a CNN that can remove large scale ringing in a deblurred image. Our method has three key points. The first is that our network architecture is able to preserve both large and small features in the image. The second is that the training dataset is created to preserve the details. The third is that we extend the images to minimize the effects of large ringing on the image borders. In our experiments, we used three kinds of large PSFs and were able to observe high-precision results from our method both quantitatively and qualitatively.


2019 ◽  
Author(s):  
Ryther Anderson ◽  
Achay Biong ◽  
Diego Gómez-Gualdrón

<div>Tailoring the structure and chemistry of metal-organic frameworks (MOFs) enables the manipulation of their adsorption properties to suit specific energy and environmental applications. As there are millions of possible MOFs (with tens of thousands already synthesized), molecular simulation, such as grand canonical Monte Carlo (GCMC), has frequently been used to rapidly evaluate the adsorption performance of a large set of MOFs. This allows subsequent experiments to focus only on a small subset of the most promising MOFs. In many instances, however, even molecular simulation becomes prohibitively time consuming, underscoring the need for alternative screening methods, such as machine learning, to precede molecular simulation efforts. In this study, as a proof of concept, we trained a neural network as the first example of a machine learning model capable of predicting full adsorption isotherms of different molecules not included in the training of the model. To achieve this, we trained our neural network only on alchemical species, represented only by their geometry and force field parameters, and used this neural network to predict the loadings of real adsorbates. We focused on predicting room temperature adsorption of small (one- and two-atom) molecules relevant to chemical separations. Namely, argon, krypton, xenon, methane, ethane, and nitrogen. However, we also observed surprisingly promising predictions for more complex molecules, whose properties are outside the range spanned by the alchemical adsorbates. Prediction accuracies suitable for large-scale screening were achieved using simple MOF (e.g. geometric properties and chemical moieties), and adsorbate (e.g. forcefield parameters and geometry) descriptors. Our results illustrate a new philosophy of training that opens the path towards development of machine learning models that can predict the adsorption loading of any new adsorbate at any new operating conditions in any new MOF.</div>


Author(s):  
Xiaochuan Tang ◽  
Mingzhe Liu ◽  
Hao Zhong ◽  
Yuanzhen Ju ◽  
Weile Li ◽  
...  

Landslide recognition is widely used in natural disaster risk management. Traditional landslide recognition is mainly conducted by geologists, which is accurate but inefficient. This article introduces multiple instance learning (MIL) to perform automatic landslide recognition. An end-to-end deep convolutional neural network is proposed, referred to as Multiple Instance Learning–based Landslide classification (MILL). First, MILL uses a large-scale remote sensing image classification dataset to build pre-train networks for landslide feature extraction. Second, MILL extracts instances and assign instance labels without pixel-level annotations. Third, MILL uses a new channel attention–based MIL pooling function to map instance-level labels to bag-level label. We apply MIL to detect landslides in a loess area. Experimental results demonstrate that MILL is effective in identifying landslides in remote sensing images.


2021 ◽  
Vol 40 (3) ◽  
pp. 1-13
Author(s):  
Lumin Yang ◽  
Jiajie Zhuang ◽  
Hongbo Fu ◽  
Xiangzhi Wei ◽  
Kun Zhou ◽  
...  

We introduce SketchGNN , a convolutional graph neural network for semantic segmentation and labeling of freehand vector sketches. We treat an input stroke-based sketch as a graph with nodes representing the sampled points along input strokes and edges encoding the stroke structure information. To predict the per-node labels, our SketchGNN uses graph convolution and a static-dynamic branching network architecture to extract the features at three levels, i.e., point-level, stroke-level, and sketch-level. SketchGNN significantly improves the accuracy of the state-of-the-art methods for semantic sketch segmentation (by 11.2% in the pixel-based metric and 18.2% in the component-based metric over a large-scale challenging SPG dataset) and has magnitudes fewer parameters than both image-based and sequence-based methods.


Sign in / Sign up

Export Citation Format

Share Document